Hycult Biotech

Name

Hycult Biotech

Legal name

Hycult Biotechnology B.V.

Website

https://hycultbiotech.com

Company type

Private

Founded year

1994

Operating status

Operating

Headcount range

11–50 employees

Ownership category

akta.pro rank

Product category

Life Sciences Research Reagents

NAICS

In-Vitro Diagnostic Substance Manufacturing (325413)

SIC

In Vitro & In Vivo Diagnostic Substances (2835)

akta.pro primary industry

Reagents, Chemicals & Assay Kits (Buffers, Antibodies, ELISA, Enzymes) (HLAGAIAI)

akta.pro secondary industry

Specialty & Biomarker Laboratory Services (Immunoassays/Flow/Cytometry) (HLAGAEAB)

Keywords

• Complement system reagents
• Innate immunity research
• ELISA assay kits
• Monoclonal antibodies research
• Complement proteins peptides

Headquarters

HQ city

's-hertogenbosch

HQ country

Netherlands

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Operations, Technology or R&D, Supply Chain, Marketing or Sales

Revenue model

1. Product Sales: Direct sales of research products including antibodies, assays (ELISA kits), and proteins/peptides to research institutions and life sciences companies worldwide through e-commerce platform and distributor network.

Pricing tiers

Go-to-market motion1 record

Distribution channels2 records

Marketing channels4 records

Core offering

Hycult Biotech manufactures and sells research-use-only antibodies, ELISA assays, and purified proteins/peptides focused on the complement system and innate immunity. It operates a direct e-commerce storefront complemented by a global distributor network, and provides contract research and manufacturing services under the Biocult sub-brand. Its portfolio serves life sciences researchers across kidney disease, neurology, infectious disease, and gastroenterology applications.

Product overview

Hycult Biotech is a biotech company specializing in antibodies, assays, and proteins for complement and innate immunity research since 1994. The company operates as a manufacturer offering a portfolio of products organized into three core categories: Antibodies (specialized antibodies for complement proteins), Assays (ELISA kits and pathway-specific assays including classical, alternative, lectin, and terminal pathway assays), and Proteins and Peptides (purified complement proteins). Key products include the C3NeF Detection ELISA Kit (HK3051), C3 Human ELISA Kit, C3bBbP ELISA Kit, and pathway-specific assays. The company also offers contract research and manufacturing services under the Biocult sub-brand, including assay development and IVDR-compliant workflows. An ELISA calculation tool is provided for data analysis.

Differentiator

Problem solved

Functional benefit

Brands

• Biocult: Contract research and contract manufacturing brand operating under Hycult Biotechnology B.V.

Products and services

• Antibodies (product line) Specialized monoclonal and polyclonal antibodies for complement and innate immunity research, targeting complement system proteins for use in immunological studies.
• Assays (product line) ELISA kits and assay solutions for detecting and measuring complement system components, including pathway-specific assays for classical, lectin, alternative, and terminal complement pathways.
• Proteins and Peptides (product line) Purified complement proteins and peptides for research applications, including Complement Factor H, Complement C3, and related proteins for innate immunity studies.
• C3NeF Detection Human ELISA Kit (HK3051) In vitro qualitative determination of C3 nephritic factor (C3NeF) autoantibodies in heat-inactivated human serum or plasma. Uses a C3b-coated plate with Factor B and Factor D to enable C3bBb convertase formation, used in complement-mediated kidney disease research.
• C3bBbP Human ELISA Kit ELISA kit for detection of the C3bBbP complex in human samples, with cross-reactivity to Cynomolgus monkey and Mouse, used in complement activation research.
• Classical Complement Pathway Human Assay Assay for measuring classical complement pathway activation in human samples, with cross-reactivity to Monkey and Pig, for innate immunity and complement research.
• Alternative Complement Pathway Human Assay Assay for measuring alternative complement pathway activation in human samples, used in complement biology and disease research.
• C3 Human ELISA Kit ELISA kit for detection of Complement C3 in human samples, with cross-reactivity to Cynomolgus monkey, supporting complement activation and quantification studies.
• Alternative Complement Pathway Mouse Assay (HIT422) Assay for measuring alternative complement pathway activation in mouse samples, used in preclinical complement research.
• C3b/iC3b Human Monoclonal Antibody 3E7 Monoclonal antibody targeting C3b/iC3b, used for research applications in complement inhibition studies.
• Biocult Services (contract research and contract manufacturing) Contract research and contract manufacturing services operated under the Biocult sub-brand, offering IVDR-compliant workflows and, as of 2026, assay development alongside established manufacturing services for life sciences partners.

Segments2 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

Nine partnerships are on record, tiered core and minor.

• Health HollandcoreStrategic or Co-development PartnerFunding partner for COMPASS project focused on developing standardized immunoassays for kidney disease care through standardized immune blood tests, in collaboration with academic medical centers.
• Horizon 2020coreStrategic or Co-development PartnerEU research and innovation program funding multiple projects: HDM-FUN (Host-Directed Medicine in invasive fungal infections), DISCOvERIE (diagnostics for IBS), and RELENT (relapse prevention in autoimmune disease).
• European Joint Programme Rare Diseases (EJP RD)coreStrategic or Co-development PartnerCOMPRare project: Towards the most accurate diagnosis and monitoring of complement-mediated rare kidney diseases, including development of C3NeF detection assay.
• MSC-ITN (Marie Skłodowska-Curie ITN)minorStrategic or Co-development PartnerCORVOS project: COmplement Regulation and Variations in Opportunistic infectionS - development of antibodies and assays for measuring complement activation in infectious diseases.
• LSH-TKI (Top Sector Life Sciences & Health)minorStrategic or Co-development PartnerFunding partner for STRIDE-COM project (kidney transplantation risk stratification) and Dual biomarker project (intestinal ischemia diagnosis).
• NWO-TTW (Netherlands Organisation for Scientific Research)minorStrategic or Co-development PartnerNACTAR project: Novel Antibacterial Compounds and Therapies antagonizing resistance via therapeutic antibodies - research tools and functional assays for assessing complement activation.
• TKI Agri & FoodminorStrategic or Co-development PartnerImmune Fitness project: Identification and validation of biomarkers for immune fitness during aging.
• INTERREGminorStrategic or Co-development PartnerHealth-i-care project: Innovations for safer healthcare, including EcHECk assay for detection of EHEC O157 infections.
• SCIFIMED ConsortiumminorStrategic or Co-development PartnerScreening of Inflammation to enable personalized Medicine: Multiplex detection system to quantify functional activity of all seven FH-protein family members.

Scale indicators2 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Bio-Techne: Bio-Techne's R&D Systems brand offers complement pathway ELISA kits, antibodies, and recombinant proteins covering classical, alternative, and lectin pathways — directly competing with Hycult's core catalog for academic immunology researchers globally.
• Abcam: Abcam is one of the largest research antibody catalogs globally, with a meaningful complement-system antibody and recombinant protein offering that competes for the same academic and translational immunology buyers as Hycult.
• Cell Signaling Technology: CST manufactures highly validated antibodies and ELISA/pathway assays for immunology research, competing head-to-head with Hycult in the immunology and innate immunity research reagent segment.
• Bethyl Laboratories: Bethyl specializes in polyclonal antibody development with a strong complement and innate-immunity antibody catalog, offering highly validated reagents similar to Hycult's specialized antibody line.
• Svar Life Sciences: Svar (formerly Euro Diagnostica) through its Wieslab brand is the historic specialist in complement pathway functional assays, directly overlapping with Hycult's alternative, classical, and lectin pathway assay products.

Broad incumbents

• Thermo Fisher Scientific: Through Invitrogen, Thermo Fisher offers broad research antibody and ELISA catalogs that overlap with Hycult's complement portfolio, leveraging larger scale, OEM relationships, and global logistics to win institutional procurement.
• Merck KGaA (MilliporeSigma): MilliporeSigma sells Calbiochem-branded complement pathway reagents, antibodies, and ELISA kits, providing a broad-line alternative that competes with Hycult across research and small-scale manufacturing markets.
• QuidelOrtho: QuidelOrtho markets complement diagnostics (e.g., CH50, AH50, C3/C4) into clinical labs, representing both an adjacent incumbent and a potential M&A or partnership candidate for translating Hycult's research reagents into IVD applications.

Emerging players

• Sino Biological: Sino Biological develops recombinant proteins and antibodies including complement-related targets, competing on breadth and price for research customers, though with less specialized innate-immunity validation than Hycult.
• GenScript: GenScript provides custom antibody and recombinant protein services plus catalog reagents for immunology research, overlapping with Hycult on contract services through GenScript's ProBio and assay development offerings.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks5 records

Key highlights6 records

Customer concentration

• Xx.com/hycultbiotech
• LinkedInlinkedin.com/company/hycult-biotech

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Subsidiaries2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Hycult Biotech