What SeqCoast Genomics does

SeqCoast Genomics is a Portsmouth, New Hampshire-based sequencing services provider founded in 2022 that specializes in microbial and small-genome genomics. The company operates a sequencing-as-a-service platform combining Illumina short-read, Oxford Nanopore long-read, and bundled hybrid sequencing with bead-beating DNA extraction and a cloud-native bioinformatics stack built on Seqera's NextFlow Tower running on AWS. It holds Oxford Nanopore Service Certified laboratory status, enabling tier-one long-read services including native strand sequencing and methylation detection.

The product catalog spans 16S/ITS amplicon sequencing, poly-A and ribodepletion RNAseq, whole-genome sequencing for phages through ~40Mbp genomes, and add-on bioinformatics covering assembly, annotation, variant calling, AMR profiling, MLST strain typing, and outbreak detection. Pricing is per-sample, ranging from $69 to $445 for sequencing and $15 to $53 for bioinformatics add-ons, with volume discounts kicking in at 24+ samples or >50Gbp. No sample minimums are required, and customers order through either a self-serve e-commerce interface or contact-based quotes for custom and enterprise projects, with sample logistics via FedEx and data delivery via SFTP, Box, or AWS S3.

SeqCoast serves academic and applied microbiology researchers, public-health and infectious-disease labs, and biopharmaceutical developers working on microbial therapeutics and vaccines. The go-to-market blends product-led growth (transparent pricing, instant online quoting, customer portal) with sales-assisted handling of large and custom projects. The company is privately held, has 1–10 employees with Ph.D.-led technical leadership and a seven-member Board of Advisors, and operates as a bootstrapped LLC with no disclosed external institutional funding.

Name

SeqCoast Genomics

Legal name

SeqCoast Genomics LLC

Website

https://seqcoast.com

Company type

Private

Founded year

2022

Operating status

Operating

Headcount range

1–10 employees

Short description

SeqCoast Genomics is a Portsmouth, NH-based provider of microbial and small-genome sequencing and bioinformatics services founded in 2022. The company serves academic, applied research, and biopharmaceutical laboratories with Illumina short-read, Oxford Nanopore long-read, and hybrid sequencing workflows.

Ownership category

akta.pro rank

Product category

Genomic Sequencing Services

NAICS

Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services (518210)

SIC

Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Genomics & Next-Generation Sequencing (NGS) Services (HLAGANAA)

akta.pro secondary industries

Bioinformatics, Multi-Omics Data Analysis & Interpretation Services (HLAGANAI), Transcriptomics & Gene Expression Profiling Services (HLAGANAE), Laboratory-Based Surveillance & Genomic Epidemiology (WGS/NGS) (HLAJABAC)

Keywords

• Microbial genomics sequencing
• Next-generation sequencing services
• Bioinformatics analysis services
• Whole genome sequencing
• Oxford Nanopore sequencing

Headquarters

HQ city

Portsmouth

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales, Supply Chain

Revenue model

1. Sequencing Services: Per-sample pricing for Illumina short-read, Oxford Nanopore long-read, and hybrid sequencing. Prices range from $69-445 for Illumina, $150-250 for Nanopore, and $245-371 for hybrid services. Volume discounts available for 24+ samples.
2. Bioinformatics Analysis Services: Add-on bioinformatics services including assembly/annotation ($28), variant calling ($15), amplicon analysis ($25), bacterial profiling ($40), differential expression ($53), and metagenomics analysis ($40) on per-sample basis.
3. DNA Extraction and Sample Preparation: DNA extraction service using bead-beating lysis ($15 add-on or standalone). SPRI bead clean and concentrate service ($10).
4. Custom Services: Custom bioinformatics projects (differential expression, metagenomics, transcriptome assembly, pangenomic analysis) and large-scale projects priced through consultation.

Pricing tiers

Go-to-market motion3 records

Distribution channels3 records

Marketing channels5 records

Core offering

SeqCoast Genomics is an expert-guided genomics core facility that sells microbial and small-genome sequencing services on Illumina short-read, Oxford Nanopore long-read, and hybrid sequencing instruments, combined with DNA extraction, sample cleanup, and bioinformatic analyses (assembly, annotation, variant calling, amplicon analysis, bacterial profiling, custom workflows). Customers order separate units of service or bundled packages, ship samples to Portsmouth, NH, and receive sequencing data and analysis deliverables via SFTP, Box, or AWS S3, typically within 14 business days.

Product overview

SeqCoast Genomics offers a comprehensive microbial and small genome sequencing service platform with multiple technology approaches (Illumina short-read, Oxford Nanopore long-read, and hybrid sequencing), sample preparation services (DNA extraction, clean & concentrate), and extensive bioinformatics analyses (assembly, annotation, variant calling, amplicon analysis, bacterial profiling). The core offering centers on sequencing services that can be ordered individually or bundled with extraction and analysis add-ons. Customers order through a streamlined online interface with flexible data delivery options (SFTP, Box, AWS S3) and receive results typically within 14 business days.

Differentiator

Problem solved

Functional benefit

Products and services

• Short Read Whole Genome Sequencing (Illumina) Illumina short-read sequencing service providing 150bp paired-end reads with Q30+ read accuracy, suitable for genotyping clones, whole population sequencing, phage sequencing, metagenomics, and amplicon/microbiome profiling. Optional PCR-free library prep is available for sensitive applications; data delivered as FASTQ via SFTP, Box, or AWS S3.
• Long Read Whole Genome Sequencing (Oxford Nanopore) Oxford Nanopore long-read sequencing service producing reads up to 100kbp for longer amplicons, repetitive plasmids or viruses, difficult-to-map regions, linked mutations in mixed populations, complex metagenomes, and base modification detection (e.g., methylation). Data delivered as FASTQ and POD5 via SFTP, Box, or AWS S3.
• 16S/ITS Amplicon Sequencing (Illumina) Illumina 16S/ITS amplicon sequencing with 300bp paired-end reads using standard 341F and 806R primers targeting the V3/V4 hypervariable regions; used for assessing species diversity and abundance in microbial communities.
• 16S/ITS Amplicon Sequencing (Nanopore) Full-length Oxford Nanopore 16S sequencing producing approximately 1500bp reads for species- and strain-level resolution; supports custom primers for ITS and other amplicons. Bulk pricing starts at 24 samples.
• Hybrid Illumina and Nanopore Sequencing Bundled service that combines Illumina short reads (greater than 50X coverage, 2x150bp) with Oxford Nanopore long reads (greater than 30X coverage) plus high molecular weight gDNA extraction, designed for building robust reference genomes across a range of genome sizes.
• Poly-A Enrichment RNAseq (Illumina) Poly-A enrichment RNA sequencing for eukaryotic mRNA, providing 150bp paired-end reads with stranded protocols for gene expression analysis and metatranscriptomics.
• Ribodepletion RNAseq (Illumina) Ribodepletion-based RNA sequencing for bacterial samples (which lack poly-A tails) or eukaryotic samples, providing 150bp paired-end reads with stranded protocols.
• Strain Typing Service Bundled service combining bead-beating extraction, short-read sequencing, and bioinformatics analysis to produce MLST (Multi-Locus Sequence Typing) reports for epidemiological surveillance and outbreak detection.
• DNA Extraction Bead-beating lysis DNA extraction service for efficient processing of tough microbes, accepting BSL2 and below organisms from frozen cell pellets or pre-grown agar plates. Available as a standalone service or add-on to sequencing.
• Clean and Concentrate (SPRI bead) SPRI bead clean and concentrate service for diluting samples or removing contaminants such as excessive EDTA, salts, phenol, and ethanol/isopropanol; typical sample recovery is greater than 80%.
• Prokaryote Assembly and Annotation Comprehensive prokaryote genome assembly and annotation service using SPAdes, Unicycler, Pilon, Racon, Medaka, and Bakta; delivers QC, assembly, polishing, and annotation with GFF3, FASTA, and TXT output files.
• Bacterial Variant Calling Bacterial variant calling using Breseq to identify mutations, structural variations, and copy number variations (CNVs) in clonal or diverse bacterial populations, with mutation summaries and CNV reports.
• Short Read Amplicon Analysis Short-read amplicon analysis pipeline using DADA2 for ASV inference with taxonomic classification against Silva, Pr2, and Unite databases, including diversity metrics and Phyloseq R objects.
• Long Read Amplicon Analysis Long-read 16S amplicon analysis for Oxford Nanopore data, using Minimap2 against the NCBI Targeted Loci database to provide species- and strain-level taxonomic assignments with higher resolution than short-read approaches.
• Bacterial Profiling and Characterization Comprehensive bacterial profiling service that bundles strain typing, antimicrobial resistance studies, virulence factor analysis, contamination monitoring, and outbreak detection with iterative longitudinal analysis capabilities.
• Custom Bioinformatics Tailored bioinformatics services including differential expression analysis using Kallisto and DESeq2, phylogenomics, metagenome assembly and binning, construct validation, and consultation sessions for non-standard experimental designs.
• Sample Shipping Services Return shipping service for customer DNA samples via FedEx, with a 2-business-day standard option in insulated rigid packaging on ice packs and an overnight expedited option for urgent projects.

Quantifiable outcome

• Sequencing data available in 14 business days or fewer
• +2 more outcomes

Named customers1 record

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration2 records

Feature6 records

Partnerships

Three partnerships are on record, tiered core.

• Oxford Nanopore TechnologiescoreTechnology or IntegrationSeqCoast is an Oxford Nanopore Service Certified laboratory, enabling them to offer highest quality long-read sequencing services. This certification ensures standardized quality protocols for Nanopore sequencing workflows.
• Seqera (NextFlow Tower)coreTechnology or IntegrationCore bioinformatics analyses are developed and processed on the secure AWS cloud-based platform using Seqera's NextFlow Tower, with version control maintained using GitHub.
• Amazon Web Services (AWS)coreTechnology or IntegrationBioinformatics pipelines operate on AWS cloud infrastructure. Data delivery options include AWS S3 bucket transfer with customer-provided 12-digit AWS Account ID for CLI access.

Scale indicators3 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• MR DNA (Molecular Research LP): MR DNA is a Texas-based research sequencing lab specializing in 16S, ITS, and shotgun metagenomics for microbiome research. Closely comparable niche, similar customer base, and overlapping amplicon/microbial WGS service offerings.
• CD Genomics: CD Genomics is a sequencing services provider focused on next-generation sequencing for microbiome, microbial, and translational research. Closely comparable to SeqCoast on microbial WGS, 16S amplicon, metagenomics, and bioinformatics services.
• SeqCenter (formerly MIGS): SeqCenter is a microbial-focused Illumina service provider (Pittsburgh, PA) offering 16S, WGS, and shotgun metagenomics for the research community. Very directly comparable to SeqCoast as a boutique microbial sequencing CRO with a similar customer profile.

Broad incumbents

• Novogene Corporation: Novogene is a major global NGS service provider serving academic, agricultural, and clinical customers with WGS, RNAseq, amplicon, and single-cell services. Directly comparable on microbial WGS, RNAseq, and metagenomics, but at a much larger scale and price-competitive at high volumes.
• Eurofins Genomics: Eurofins operates a global sequencing services business covering Sanger, NGS, oligonucleotide synthesis, and bioinformatics. Directly competes with SeqCoast on microbial and amplicon sequencing but with substantially larger scale, broader menu, and pharma GLP workflows.
• Azenta Life Sciences (formerly Genewiz): Azenta owns Genewiz, the largest direct competitor in research-grade Sanger and NGS sequencing services globally. Overlaps with SeqCoast on Illumina WGS, amplicon, and bacterial sequencing, but at vastly greater scale and with a much broader service menu.

Regional players

• Psomagen: Psomagen (formerly Macrogen USA) provides NGS, microarray, and bioinformatics services to North American researchers. Comparable on microbial WGS, amplicon, and RNAseq services, with stronger presence in the US East Coast and federal research markets.
• Microsynth: Microsynth is a European sequencing services provider (Switzerland/Austria) offering Sanger, NGS, qPCR, and microbial sequencing. Overlaps with SeqCoast on microbial WGS and amplicon services but operates primarily in the European market.

Emerging players

• Theiagen Genomics: Theiagen Genomics, founded by SeqCoast advisor Joel Sevinsky, provides public-health bioinformatics and genomic epidemiology services to state health departments. Comparable in microbial/public-health bioinformatics focus, but positioned upstream as a software/services platform rather than a wet-lab CRO.
• Day Zero Diagnostics: Day Zero Diagnostics develops sequencing-based infectious disease diagnostics and previously employed SeqCoast's Senior Director Nicole Billings to lead its CLIA-compliant lab. Relevant adjacent peer in clinical pathogen genomics, though more diagnostic-product oriented than services oriented.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/seqcoast-genomics
• Xx.com/seqcoast

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles5 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about SeqCoast Genomics