Trial Management Associates

What Trial Management Associates does

Trial Management Associates (TMA) is a fully integrated clinical research management company that manages and coordinates Phase II-IV industry-sponsored clinical drug trials and research studies on behalf of pharmaceutical sponsors and Contract Research Organizations (CROs). Founded around 2010 in Wilmington, NC, TMA operates an Integrated Site Network (ISN) based at private physician practices, staffed with qualified Principal Investigators, Site Managers, and Clinical Research Coordinators who execute trials from initial screening through close-out. The company holds two dedicated research facilities — one in Wilmington, NC (3806 Peachtree Ave. Suite 100 / 1221 Floral Parkway Suite 101) and one in Myrtle Beach, SC (945 82nd Parkway) — and partners with private practices across gastroenterology, dermatology, infectious disease, and family medicine to broaden therapeutic area coverage. Operations are ICH-GCP and HIPAA compliant, and TMA conducts trials across 50+ therapeutic areas including vaccines, COVID-19, RSV, influenza, diabetes, hypertension, dermatology, gastroenterology, nephrology, pulmonology, endocrinology, and cardiology.

TMA serves three customer segments: (1) pharmaceutical sponsors and CROs seeking reliable sites with strong enrollment performance, (2) private physician practices that want to participate in research without building standalone infrastructure, and (3) study volunteers who receive study-related care at no cost plus compensation for time. The company generates revenue through professional-services fees paid by sponsors and CROs per trial managed, with go-to-market executed through enterprise-level direct sales relationships with sponsors on one side and a community-led recruitment funnel (website forms, referrals, healthcare-provider outreach, $100 referral bonuses) on the other. TMA is operationally integrated into Headlands Research's ISN, a Lake Worth, FL-based platform backed by KKR, which extends TMA's access to broader sponsor relationships and capital. Notable milestones include selection in 2020 as one of only ten US sites for Moderna's Phase II mRNA-1273 SARS-CoV-2 vaccine trial and the subsequent addition of two further COVID-19 vaccine trials at the Wilmington site in November 2020.

Name

Trial Management Associates

Legal name

Trial Management Associates, LLC

Website

https://trialmgt.com

Company type

Private

Founded year

2010

Operating status

Operating

Headcount range

11–50 employees

Short description

Trial Management Associates is a clinical research site management company that runs Phase II-IV industry-sponsored drug trials from private physician practice locations in Wilmington, NC and Myrtle Beach, SC, serving pharmaceutical sponsors, CROs, and study volunteers across 50+ therapeutic areas.

Ownership category

akta.pro rank

Product category

Clinical Research Services

NAICS

Scientific Research and Development Services (5417)

SIC

Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Clinical Trial Site Operations & Study Coordination (HLAGACAE)

akta.pro secondary industry

Clinical Trial Monitoring Support (On-site/Remote) (HLAGACAG)

Keywords

• Clinical trial management
• Phase II-IV trials
• Clinical research site network
• Investigator site services
• Sponsor and CRO services

Headquarters

HQ city

Wilmington

HQ country

United States

HQ region

North America

Offices3 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Infrastructure, Marketing or Sales, Technology or R&D

Revenue model

1. Clinical Trial Management Services: TMA generates revenue by managing Phase II-IV industry-sponsored clinical trials for pharmaceutical sponsors and CROs. Services include site management, participant recruitment, data management, budget negotiations, regulatory documentation, and quality assurance. The company receives compensation per trial conducted.

Go-to-market motion2 records

Distribution channels2 records

Marketing channels4 records

Core offering

Trial Management Associates (TMA) is a fully integrated clinical research management company that partners with private physician practices to manage and execute Phase II-IV industry-sponsored clinical drug trials and research studies. Services span from initial volunteer screening through close-out visit, including dedicated Clinical Research Coordinators, regulatory documentation, participant recruitment, quality data management, and budget negotiations on behalf of pharmaceutical sponsors and Contract Research Organizations.

Product overview

Trial Management Associates (TMA) is a fully integrated clinical research management company that operates as a single unified service offering rather than a modular platform. The core offering combines clinical trial management services with an Integrated Site Network (ISN) of private physician practice locations. TMA provides end-to-end services including volunteer recruitment through its Current Clinical Trials Platform, physician/investigator partnership programs, and dedicated sponsor/CRO trial coordination. The company specializes across nine therapeutic areas (Vaccines, Family Medicine, Nephrology, Gastroenterology, Infectious Disease, Endocrinology, Dermatology, Pulmonology, and Cardiology) and conducts Phase II-IV clinical trials. All services are delivered through qualified investigators, site managers, and research coordinators working from initial screening through close-out visit.

Differentiator

Problem solved

Functional benefit

Products and services

• Clinical Trial Management Services A fully integrated clinical research management service for pharmaceutical sponsors and CROs, partnering with private physician practices to plan and execute Phase II-IV industry-sponsored clinical drug trials and research studies from initial screening through close-out visit. Includes dedicated Investigators, Site Managers, and Clinical Research Coordinators.
• Current Clinical Trials Platform An online volunteer registration and clinical trial listing platform where prospective study volunteers can review current studies and submit volunteer forms for consideration. Available to individuals interested in participating in clinical research.
• Physician/Investigator Partnership Program A partnership program that staffs private practice physicians with experienced Clinical Research Coordinators and Site Managers to enable the physicians to conduct clinical trials at their practices, offering supplemental income, enhanced CV, and access to cutting-edge therapies for their patients.
• Sponsor/CRO Trial Management Comprehensive trial coordination services delivered directly to pharmaceutical sponsors and Contract Research Organizations, including dedicated Clinical Research Coordinators, regulatory documentation, quality data management, budget negotiation, and participant recruitment against enrollment targets.
• Integrated Site Network (ISN) A network of investigative sites staffed with qualified Investigators, Site Managers, and Research Coordinators operating at private physician practices and dedicated research facilities, providing sponsors with access to diverse patient populations across multiple therapeutic areas.

Quantifiable outcome

• Successful enrollment in Moderna COVID vaccine Phase II trial as one of only 10 sites nationwide
• +1 more outcomes

Named customers1 record

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Partnerships

Six partnerships are on record, tiered core and minor.

• Elite Research NetworkcoreStrategic or Co-development Partner · 1 January 2019Mount Pleasant, South Carolina-based Elite Research Network partnered with TMA to expand clinical trial opportunities. The partnership provides TMA access to a North American research network of approximately 50 strategically aligned sites, enabling geographic expansion and additional therapeutic area coverage. TMA brings access to patient populations in gastroenterology, dermatology, and family practice.
• Headlands ResearchcoreOthersHeadlands Research is TMA's parent company. Based in Lake Worth, FL and backed by KKR, Headlands Research operates as a platform of best-in-class research facilities. TMA operates as part of the Headlands Research Integrated Site Network.
• Wrightsville Family PracticecoreStrategic or Co-development PartnerWrightsville Family Practice, led by Drs. Bart Williams and Will Jones, serves as a key investigator site for TMA. Dr. Bart Williams serves as Principal Investigator for multiple trials including Moderna's COVID vaccine trial.
• Wilmington Gastroenterology AssociatesminorStrategic or Co-development PartnerPartner physician practice providing investigative site capabilities, particularly for gastroenterology-related clinical trials.
• Dermatology AssociatesminorStrategic or Co-development PartnerPartner physician practice providing investigative site capabilities for dermatology clinical trials.
• Coastal Infectious Disease ConsultantsminorStrategic or Co-development PartnerPartner physician practice providing investigative site capabilities for infectious disease clinical trials.

Scale indicators3 records

Recent moves6 records

Expansion highlights5 records

Market position

Competitive moat4 records

Key highlights6 records

Customer concentration

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Trial Management Associates