Olympic Protein Technologies

What Olympic Protein Technologies does

Olympic Protein Technologies (OPT) is a Seattle-based contract research organization that provides custom protein science services to biotechnology and pharmaceutical drug discovery teams. Its service portfolio spans the full protein production workflow: molecular biology (gene design, subcloning, antibody panel construction, and hybridoma variable domain sequencing); recombinant expression across three platforms — baculovirus-infected insect cells, E. coli (soluble and refolded from inclusion bodies), and transient mammalian HEK293/CHO; purification using affinity, ion exchange, size exclusion, and other chromatographies with fluorescent labeling and biotinylation; analytical characterization including SDS-PAGE, Western blot, analytical SEC, SEC-MALS, endotoxin measurement, and mass spectrometry (via partners); structure-based protein engineering with library design, mutant screening, and epitope mapping; and Biacore surface plasmon resonance (SPR) services for affinity/kinetics determination, epitope binning, custom reagent generation, and assays suitable for regulatory submissions. The company complements its fee-for-service work with a small catalog of Biacore-quality-tested SPR reagents, beginning with His-Avi tagged human Fc gamma Receptor III (158V and 158F) and human FcRn complexed with beta-2-microglobulin.

OPT generates revenue through project-based fee-for-service engagements priced by scope and complexity. Customers engage directly via phone (206-849-9811), email ([email protected]), or the website contact form, and OPT is also listed on the Science Exchange and Scientist.com marketplaces used by pharma and biotech procurement teams. The company positions itself on personalized technical engagement — named team members, including CEO Derek Piper and CSO Michael Wittekind, work directly on client projects rather than via account managers — and on secure on-site execution in a single Seattle laboratory at 454 N 34th Street. Its primary customer segment is biotech and pharma drug discovery teams working on antibodies, antibody-drug conjugates, bispecifics, and protein fusions, with academic research labs as a secondary segment.

The leadership carries significant pedigree from major biopharmaceutical companies: Piper was previously Senior Director at Exelixis and Principal Scientist at Amgen, and holds 70+ patents/applications; Wittekind was CSO at ContraFect and Executive Director of Research at Amgen, where he led 11 programs from discovery into preclinical/clinical stages; their work supported approved therapeutics including Repatha, Siliq, Cialis, and Reyataz/Evotaz. OPT is privately held with no disclosed funding rounds, parent company, or ownership structure.

Name

Olympic Protein Technologies

Legal name

Olympic Protein Technologies

Website

https://opt.bio

Company type

Private

Founded year

2017

Operating status

Operating

Headcount range

11–50 employees

Short description

Olympic Protein Technologies is a Seattle-based contract research organization providing custom protein science services — molecular biology, multi-system expression, purification, engineering, and Biacore SPR analysis — to biotech and pharmaceutical drug discovery teams, supplemented by a catalog of Biacore-qualified reagents.

Ownership category

akta.pro rank

Product category

Contract Research Services (Protein Sciences)

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714)

SIC

Services-Commercial Physical & Biological Research (8731), Services-Testing Laboratories (8734)

akta.pro primary industry

Proteomics & Mass Spectrometry Services (HLAGANAB)

akta.pro secondary industry

Proteomics & Biomarker Analytical Testing (HLAGADAG)

Keywords

• Protein expression services
• Protein purification services
• Surface plasmon resonance
• Contract research organization
• Recombinant protein production

Headquarters

HQ city

Seattle

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Infrastructure, Technology or R&D, Marketing or Sales

Revenue model

1. Contract Research Services (Fee-for-Service): Project-based fee-for-service model where OPT provides custom protein science services including construct design, expression, purification, characterization, biomolecular interaction analysis, and protein engineering. Services are priced per project based on scope, expression systems used, and analysis requirements. As a CRO, revenue is generated through service contracts with biotech and pharma clients.

Pricing tiers

Go-to-market motion1 record

Distribution channels3 records

Marketing channels4 records

Core offering

Olympic Protein Technologies is a contract research organization providing custom protein science services to biotech and pharmaceutical clients. Services span molecular biology, protein expression (insect, E. coli, mammalian systems), purification, analysis, engineering, and surface plasmon resonance (SPR) interaction analysis, all executed at an on-site laboratory in Seattle, Washington. OPT also sells a catalog of Biacore-qualified SPR reagents.

Product overview

Olympic Protein Technologies (OPT) is a contract research organization (CRO) providing a comprehensive suite of custom recombinant protein science services. The core offering consists of integrated molecular biology, protein expression (mammalian, insect, and bacterial systems), protein purification, protein analysis, protein engineering, and surface plasmon resonance (SPR) services, all executed at their Seattle, WA laboratory. OPT complements their service offerings with a catalog of Biacore SPR reagents (Fc gamma Receptor III variants and FcRn complexes) that have passed Biacore quality testing. The company also distributes their services through marketplace platforms including Science Exchange and Scientist.com.

Differentiator

Problem solved

Functional benefit

Products and services

• Molecular Biology Services DNA construction and cloning services including new gene design and synthesis, subcloning into expression vectors, antibody panel construction, and hybridoma variable domain sequencing, intended for biotech and pharmaceutical researchers needing custom expression-ready DNA constructs.
• Protein Expression Services Recombinant protein expression in mammalian cells (HEK293 and CHO), baculovirus-infected insect cells, and bacterial cells (E. coli), including small-scale testing, scale-up production, and stable pool generation for biotech and pharmaceutical clients.
• Protein Purification Services Protein purification from various expression systems using affinity, ion exchange, size exclusion, and other chromatography methods, including protein refolding from E. coli inclusion bodies and fluorescent labeling and biotinylation modifications.
• Protein Analysis Services In-house protein characterization including SDS-PAGE, Western blot, analytical SEC, SEC-MALS, endotoxin level measurement, and spectrometric measurements, with additional mass spectrometry and N-terminal sequencing available through partners.
• Protein Engineering Services Structure-based protein design analysis, single or multiple point mutants and screening, library design and screening, and epitope mapping for antibody programs.
• Surface Plasmon Resonance (SPR) Services Biacore SPR-based biomolecular interaction analysis including affinity and kinetic constant determinations, epitope binning, custom Biacore reagent generation, and assay development for small molecules, mAbs, ADCs, bispecifics, and peptides.
• Biacore SPR Reagents Catalog Pre-qualified SPR reagents including human Fc gamma Receptor III (158V and 158F variants) and human FcRn complexed with human beta-microglobulin (all as His-Avi tagged constructs), quality-tested for Biacore SPR performance.

Quantifiable outcome

• 11 programs transitioned from discovery to preclinical/clinical stages under CSO Michael Wittekind's leadership at Amgen
• +2 more outcomes

Segments2 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Two partnerships are on record, tiered core.

• Science ExchangecoreChannel Partner/ Reseller/ DistributorOPT is listed on the Science Exchange marketplace, an online platform connecting researchers with contract research service providers. This partnership provides access to Science Exchange's customer base of researchers seeking protein science services.
• Scientist.comcoreChannel Partner/ Reseller/ DistributorOPT is listed on Scientist.com marketplace, a platform serving pharma and biotech companies with research service providers. This marketplace listing enables OPT to reach institutional buyers using the platform for vendor management and procurement.

Scale indicators2 records

Expansion highlights3 records

Broad incumbents

• Eurofins Scientific: Eurofins runs a global network of testing and contract research laboratories including protein, biopharmaceutical, and bioanalytical services. It competes with specialty protein CROs through scale, multi-site capacity, and broad analytical menus.
• Charles River Laboratories: Charles River is a large CRO offering discovery, safety assessment, and manufacturing services including biologics support. Its broad portfolio and global footprint make it a higher-end incumbent competing with specialty protein CROs on larger integrated programs.
• WuXi Biologics: WuXi Biologics is a global biologics CRO/CDMO offering discovery, cell line development, and GMP manufacturing. As a broad incumbent it competes with specialty protein CROs on discovery-stage work where it can bundle upstream and downstream services.

Direct peers

• Bio-Techne: Bio-Techne provides proteins, antibodies, and assays for life science research, including custom protein services and GMP-grade reagents. While larger and more catalog-oriented than OPT, it serves the same biotech/protein-reagent buyer with overlapping custom offerings.
• Proteros biostructures: Proteros offers custom protein production, protein crystallography, and biophysical analysis (including SPR) for structure-based drug design. Its protein science service portfolio and target customer base (drug discovery teams) overlap closely with OPT.
• Absolute Antibody: Absolute Antibody provides recombinant antibody expression, antibody engineering, and SPR-based characterization services with a focus on sequencing and recombinant formats. It targets the same antibody engineering and biophysical characterization niche as OPT.
• Sino Biological: Sino Biological offers custom recombinant protein production (multi-system), antibody development, and protein reagents for research and therapeutic discovery. It overlaps with OPT on custom protein services and reagent catalog.
• GenScript: GenScript is a global CRO that provides gene synthesis, protein expression and purification, antibody production, and peptide services to biotech and pharma. It directly competes with OPT across the custom protein production workflow, with broader catalog scale.
• ProteoGenix: ProteoGenix specializes in recombinant protein expression, antibody production (including bispecifics and ADCs), and protein engineering services for biotech clients. It competes head-to-head with OPT on custom protein and antibody projects.

Others

• Cytiva (formerly GE Life Sciences): Cytiva supplies the Biacore SPR instruments and reagents that OPT's SPR service line is built around. It is an enabling technology vendor rather than a direct CRO competitor, but its product roadmap and service-partner relationships directly affect OPT's SPR delivery model.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/olympicproteintechnologies/about/?viewAsMember=true

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Olympic Protein Technologies