Physiodermie

What Physiodermie does

Physiodermie is a Swiss cosmeceutical skincare brand founded in 1974, operated under the parent entity LABORATOIRE SINTYL SA, headquartered at 23 Route des Jeunes in Geneva, Switzerland. The company develops and manufactures skincare formulations built around its proprietary Multi-Active Micro-Encapsulation (MEIMA) delivery technology, which enables targeted release of active ingredients into the skin, and a proprietary vitamin A derivative called Retinyl Retinoate. Its product range is organized into four collections: Clinical Swiss Organics (COSMOS ORGANIC certified by ECOCERT Greenlife), Equilibre Essentiel (essential-oil serums using MEIMA), Chrono Repair (anti-aging featuring Retinyl Retinoate), and Time Protect (suncare). The portfolio spans cleansers, toners, boosters, serums, emulsions, eye care, masks, exfoliators, sun care, and gift sets at premium price points ranging from €41 to €200.

The company operates a multi-channel go-to-market model. Direct-to-consumer e-commerce via physiodermie.com serves Europe and Switzerland (free shipping over 200 CHF, with international delivery to 25+ European countries plus Singapore). A professional channel serves a network of 1000+ dermo-therapists in 20 countries who provide skincare consultations and recommend products; registered dermo-therapists access a B2B portal for cabin products, marketing materials, and samples, supplemented by a Premium Partners program and Physiodermie Academy training. A spa and wellness establishment channel offers branded treatment protocols. Manufacturing is handled by the wholly owned subsidiary NBC COSMETICS at a facility in Prevessin-Moëns, France, with regional operations run from LABORATOIRE SINTYL SINGAPORE PTE LTD.

Physiodermie is a privately held company with no evidence of venture capital or private equity backing, suggesting stable independent ownership since 1974. Revenue is not publicly disclosed. Recent strategic activity has focused on expanding the product portfolio (Time Protect suncare, Prebiotic Mist, body care line in 2024) and extending geographic reach into the Asia-Pacific region via the Singapore subsidiary, while deepening the professional dermo-therapist channel through the Premium Partners program.

Name

Physiodermie

Legal name

LABORATOIRE SINTYL SA

Website

https://physiodermie.com

Company type

Private

Founded year

1974

Operating status

Operating

Headcount range

11–50 employees

Short description

Physiodermie is a Swiss cosmeceutical skincare brand founded in 1974, operating under LABORATOIRE SINTYL SA in Geneva. It sells premium anti-aging, organic, and suncare products (€41–€200) through DTC e-commerce and a network of 1000+ dermo-therapists across 20 countries.

Ownership category

akta.pro rank

Product category

Professional Cosmeceutical Skincare

NAICS

Soap and Cleaning Compound Manufacturing (32561), Health and Personal Care Retailers (456)

SIC

Perfumes, Cosmetics & Other Toilet Preparations (2844)

akta.pro primary industry

Dermocosmetics & Medical-Grade Skincare (CRABAAAF)

akta.pro secondary industries

Natural/Organic & Clean Skincare (CRABAAAH), Sensitive Skin & Barrier Repair (CRABAAAG), Professional Skincare & Facial Treatments (CRABALAF)

Keywords

• Professional skincare products
• Anti-aging cosmeceuticals
• Organic facial care
• Swiss dermatological formulations
• Skincare treatment serums

Headquarters

HQ city

Genève

HQ country

Switzerland

HQ region

Europe

Offices3 records

Markets served

GTM type

B2B and B2C

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Personnel, Technology or R&D, Marketing or Sales

Revenue model

1. Direct Product Sales (B2C): Consumer e-commerce sales through physiodermie.com website. Products sold at various price points from €41 to €200+. Free shipping to Europe and Switzerland on orders over 200 CHF. Accepts Visa, Mastercard, Postfinance, American Express, and PayPal.
2. Professional/ B2B Sales: Sales to registered dermo-therapists and Premium Partners through B2B portal, offering cabin products, marketing materials, and samples
3. Spa Treatment Services: Revenue from spa treatment protocols and services offered through partner establishments

Pricing tiers

Go-to-market motion2 records

Distribution channels4 records

Marketing channels5 records

Core offering

Physiodermie develops, manufactures and sells Swiss-made cosmeceutical skincare products across four collections (Clinical Swiss Organics, Equilibre Essentiel, Chrono Repair, Time Protect), encompassing cleansers, serums, emulsions, masks, eye care, suncare and curated kits. The products are formulated in the Geneva laboratory using the proprietary MEIMA micro-encapsulation technology and Retinyl Retinoate active, and are sold directly to consumers via physiodermie.com and through a network of 1,000+ Dermo-Therapists and spa partners in 20 countries.

Product overview

Physiodermie is a Swiss cosmeceutical skincare brand founded in 1974, with laboratories located in Geneva, Switzerland. The company operates through LABORATOIRE SINTYL SA and serves consumers via a network of over 1000 Dermo-Therapists in 20 countries, as well as direct-to-consumer e-commerce. Physiodermie's product portfolio consists of four main collections: Clinical Swiss Organics (COSMOS ORGANIC certified products like Glow Booster Set, Lipid Restore Mask, High Purity Serum, Shot C15); Equilibre Essentiel (essential oil-based products including various Bioarome serums like Bioarome RC Revitalizing, Bioarome DS Anti-Impurities, Bioarome DEP Purifying); Chrono Repair (anti-aging solutions featuring Retinoate Program, Ultra Intensive Eye Cream); and Time Protect (suncare including Suncare Water SPF50+). The company also offers a comprehensive range of face care products including cleansers (Deep Cleansing Balm, Stabilizing Lotion), serums (Bi-Molecular Hyaluronic Acid, Prebiotic Mist, Revit(a) Oil), emulsions (Hydraceramides Emulsion, Sensitive Skin Emulsion, All Time3 Emulsion), masks (Recovery Night Mask), and specialized treatments. All formulations utilize the proprietary MEIMA (Multi-Active Micro-Encapsulation) technology for enhanced ingredient delivery and efficacy.

Differentiator

Problem solved

Functional benefit

Brands

• Clinical Swiss Organics: Certified organic skincare collection with COSMOS ORGANIC certification by ECOCERT.
• Equilibre Essentiel
• Chrono Repair
• Time Protect

Products and services

• Clinical Swiss Organics Collection
• Equilibre Essentiel Collection
• Chrono Repair Collection
• Time Protect Collection
• Bi-Molecular Hyaluronic Acid
• Shot C15
• Hydraceramides Emulsion
• Micropeeling AHA
• Sublimating Cream
• Recovery Night Mask
• Eye Contour Gel
• Ultra Intensive Eye Cream
• Suncare Water SPF50+
• High Purity Purifying Serum
• Prebiotic Mist
• Retinoate Program
• Revit(a) Oil
• Bioarome RC Revitalizing
• Bioarome DS Anti-Impurities
• Bioarome DEP Purifying
• Sensitive Skin Emulsion
• Deep Cleansing Balm
• Stabilizing Lotion
• Redness Rescue
• All Time³ Emulsion
• Glow Booster Set
• Lipid Restore Mask Set
• Spa Treatment Protocols

Quantifiable outcome

• 1000+ Dermo-Therapists in 20 countries trust Physiodermie
• +1 more outcomes

Named customers3 records

Segments2 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

Four partnerships are on record, tiered core.

• LABORATOIRE SINTYL SAcoreOthersParent company and primary seller of Physiodermie products. Based in Geneva, Switzerland. Responsible for product development, manufacturing, and quality control. Also operates NBC COSMETICS manufacturing facility in France and LABORATOIRE SINTYL SINGAPORE for regional operations.
• ECOCERT GreenlifecoreOthersIndependent certification body that certifies Physiodermie's Clinical Swiss Organics Collection according to COSMOS organic standards. Verification process ensures compliance with organic label specifications.
• Premium PartnerscoreStrategic or Co-development PartnerSelect professional skincare providers who have an enhanced partnership with Physiodermie. These partners receive specialized training, marketing support, and priority access to new products and formulations.
• Dermo-Therapists (1000+)coreChannel Partner/ Reseller/ DistributorLicensed skincare professionals in 20 countries who provide professional consultations and recommend Physiodermie products to their clients. Registered through B2B portal for ordering cabin products, marketing materials, and samples.

Scale indicators3 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Dermalogica: Dermalogica is a leading professional skincare brand built around licensed skin therapists and a network of concept-skin centers. Like Physiodermie, it sells through a professional channel and direct-to-consumer channels, with positioning in cosmeceutical-grade facial care.
• SkinCeuticals: SkinCeuticals (L'Oréal) is a benchmark cosmeceutical brand that formulates science-backed skincare (Vitamin C, retinol, AHAs) sold through dermatologists, medi-spas, and its own DTC site — directly comparable to Physiodermie's physician/professional-channel-plus-DTC approach.
• Biologique Recherche: French-origin professional skincare brand selling high-concentration serums and protocols through estheticians and Ambassadeurs (their equivalent of Physiodermie's dermo-therapists). Closely aligned business model and premium positioning.
• Institut Esthederm: Institut Esthederm is a French dermo-cosmetic brand owned by NAOS that markets through esthetician networks and spas with cosmeceutical positioning in cellular water and suncare — overlapping Physiodermie's core categories.
• PCA Skin: PCA Skin is a professional-grade peel and corrective skincare brand sold through licensed estheticians, dermatologists, and spas with its own e-commerce site — structurally identical to Physiodermie's professional-plus-DTC model.
• iS Clinical: iS Clinical is a cosmeceutical skincare brand sold through physicians, spas, and its own DTC channels with pharmaceutical-grade actives — a closely comparable professional skincare brand with premium price points.
• Swissline: Swissline is a Swiss professional skincare brand with cellular-therapy heritage sold through spas, estheticians, and its own DTC site — directly comparable to Physiodermie's Swiss-made cosmeceutical positioning.
• Cellcosmet: Cellcosmet is a Swiss cellular-cosmetics brand sold through spas and DTC channels in Europe and internationally — sharing Swiss premium positioning, professional distribution, and luxury price points with Physiodermie.

Emerging players

• Dr. Dennis Gross Skincare: Dr. Dennis Gross is a dermatologist-founded cosmeceutical brand with premium pricing and DTC focus, overlapping with Physiodermie's anti-aging and peel portfolio (e.g., Micropeeling AHA), though more DTC-led than professional-channel-led.

Broad incumbents

• L'Oréal Dermatological Beauty Division: L'Oréal's dermatological beauty division (La Roche-Posay, Vichy, SkinCeuticals, CeraVe) competes across the cosmeceutical and pharmacy-dermo category and serves as the dominant incumbent reference for any professional/dermo-cosmetic peer like Physiodermie.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks5 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/channel/UCEr-oIfRZFSIDZdeP5oSyWg/featured
• Facebookfacebook.com/physiodermie
• LinkedInlinkedin.com/company/laboratoire-sintyl/mycompany
• Instagraminstagram.com/physiodermie

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Subsidiaries2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Physiodermie