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BIA Separations

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Namestring
BIA Separations
Legal namestring
BIA Separations
Company typeenum
Private
Founded yearint
1998
Descriptiontext

BIA Separations is a Slovenia-based developer and manufacturer of monolithic chromatography technology used in downstream purification of complex biological products. Founded in 1998 and headquartered in Ajdovščina with a second facility in Bled, the company operates under the Sartorius BIA Separations brand as part of the Sartorius Group, and employs 101–250 people. Its core product line is the CIMmultus family of Convective Interaction Media (CIM) monolithic chromatography columns, with CIMmultus QA HR positioned for scalable AAV capsid enrichment in gene therapy manufacturing, delivering documented performance of 88% ± 9% full capsid purity and 77% ± 3% genome recovery across scales from 1 mL to 8000 mL.

The company's technology is built on a proprietary monolithic stationary phase architecture that supports both bind-elute and flow-through operating modes, with an optimized step elution method that reduces process time relative to traditional linear-gradient approaches. Revenue is generated through direct enterprise sales of chromatography columns and consumables to gene therapy manufacturers (primary segment) and broader biopharmaceutical manufacturers producing proteins, vaccines, and viral vectors (secondary segment). Distribution is direct and global, leveraging Sartorius' bioprocessing sales infrastructure.

Complementing its product business, BIA Separations invests in scientific community-building activities, most notably the MSS (Monolith Summer School / bioprocessing symposium) series — with MSS2026 scheduled as a three-day event in Bled, Slovenia on September 14–16, 2026, combined with wet lab workshops at the Ajdovščina facility — functioning as both a customer-engagement and thought-leadership mechanism targeting the AAV/gene therapy and biologics manufacturing communities.

Short descriptiontext

BIA Separations, a Sartorius company, develops and manufactures monolithic chromatography columns (CIMmultus) for downstream purification of AAV vectors, proteins, and viral vectors, serving gene therapy and biopharmaceutical manufacturers globally through direct enterprise sales.

Operating statusenum
Operating
Ownership categoryenum
Headcount rangeband
101–250
akta.pro rankint
HeadquartersAjdovscina, Slovenia
HQ citystring
Ajdovscina
HQ countrystring
Slovenia
HQ regionstring
Europe
Markets served

Serves global market

Offices2 records

Each record includes

City, Country, Type, Description, Source

Keyword5 values
monolithic chromatography columns, biopharmaceutical purification, gene therapy manufacturing, downstream bioprocessing, AAV vector purification
Industry3 codes
1Downstream Processing & Purification Technologies (chromatography, filtration, centrifugation)
CodeHLAAAJABPrimaryYes
2Bioprocess Consumables & Reagents (resins, membranes, media components, buffers)
CodeHLAAAJAIPrimaryNo
3Analytical Instruments & Chromatography Systems
CodeHLAGAIAAPrimaryNo
NAICS code1 code
  • Analytical Laboratory Instrument Manufacturing334516
SIC code1 code
  • Laboratory Analytical Instruments3826
Product category
Bioprocessing Chromatography Consumables
GTM motion2 records

Each record includes

Type, Description, Source

Revenue model1 record
1Chromatography Products and Consumables
TypeHardware Sales
Description

Sale of CIMmultus monolithic chromatography columns and related consumables for biopharmaceutical purification applications

nature.com
Marketing channels1 record

Each record includes

Title, Type, Stage, Description, Source

Distribution channels1 record

Each record includes

Title, Type, Scope, Target buyer, Description, Source

Cost components4 values
Personnel, Operations, Technology or R&D, Marketing or Sales
GTM typeB2B
B2B
Offering typeHardware or Manufacturing
Hardware or Manufacturing
Brand1 record
1CIMmultus
Description

Monolithic chromatography columns for biopharmaceutical purification including AAV vectors, proteins, and viral vectors.

nature.com
Core offering1 text field

BIA Separations develops, manufactures, and supplies CIMmultus monolithic chromatography columns, with the CIMmultus QA HR (high-resolution) line as a flagship product, for downstream purification of biological products including AAV vectors, viral vectors, and proteins. The columns are used by gene therapy manufacturers and biopharmaceutical manufacturers to capture, purify, and polish large biomolecules in industrial and clinical-scale bioprocessing workflows.

Differentiator
Functional benefit
Problem solved
Quantifiable outcome1 of 3 values shown
  • 88% ± 9% full capsid purity achieved across scales from 1 mL to 8000 mL
+2 more records
Product overview1 text field

BIA Separations, a Sartorius company, provides monolithic chromatography products for biopharmaceutical purification. The core product offering includes the CIMmultus QA HR line of monolithic chromatography columns designed for scalable AAV vector manufacturing and gene therapy production. The company also offers bioprocessing symposiums (MSS) and wet lab workshops as part of their customer engagement and training services.

Scale indicator1 record

Each record includes

Type, Value, Description, Source

Partnership1 partner
Strategic tierCoreTypeOthers
Description

BIA Separations operates under the Sartorius brand as Sartorius BIA Separations, indicating a subsidiary or integrated business unit relationship within the larger Sartorius Group, a global life science and bioprocessing company.

Recent move4 records

Each record includes

Date, Type, Title, Description, Source

Expansion highlight4 records

Each record includes

Type, Description

Peers10 records
TypeEmerging player
Description

Supplies bioprocessing consumables including chromatography resins, buffers, and single-use solutions to gene therapy and biologics manufacturers, with increasing focus on the viral vector purification workflow.

TypeBroad incumbent
Description

Parent/affiliated bioprocessing platform offering a broad portfolio of filtration, fermentation, and purification solutions. BIA operates within this portfolio, so Sartorius is both parent and broader incumbent competitor in adjacent bioprocessing categories.

TypeDirect peer
Description

Specializes in bioprocessing solutions including OPUS pre-packed chromatography columns and filtration products used in gene therapy and biologics manufacturing — competing directly in downstream purification consumables.

TypeDirect peer
Description

Provides a broad portfolio of chromatography resins, membrane adsorbers, and bioprocessing consumables for biologics and viral vector purification, directly competing in downstream processing.

TypeDirect peer
Description

Supplies chromatography media, NGC systems, and process-scale columns for biopharmaceutical purification, overlapping with BIA's downstream purification offering for biologics and viral vectors.

TypeDirect peer
Description

Through its Patheon and bioproduction units, offers POROS chromatography resins widely used for AAV and viral vector purification, positioning it as a primary alternative to BIA's monolithic columns.

TypeDirect peer
Description

Manufactures chromatography resins (TOYOPEARL and TSKgel) used in biologics purification, including applications in gene therapy and vaccine manufacturing — a direct competitor in resin-based downstream processing.

TypeDirect peer
Description

Global bioprocessing leader offering ÄKTA chromatography systems and resin-based columns for downstream purification of biologics, viral vectors, and AAV — directly competing with BIA's monolithic offering in gene therapy and vaccine workflows.

TypeEmerging player
Description

Provides virus filtration and select purification technologies used in biopharmaceutical manufacturing, overlapping with BIA's downstream processing solutions for viral vectors and biologics.

TypeDirect peer
Description

Manufactures chromatography resins including Praesto agarose-based resins targeted at AAV and biologics purification, positioning it as a direct competitor in process-scale downstream purification.

Market position
Strengths4 records

Each record includes

Headline, Details, Source

Weaknesses4 records

Each record includes

Headline, Details, Source

Competitive moat4 records

Each record includes

Type, Details

Key risks6 records

Each record includes

Headline, Details, Source

Key highlights6 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Segment2 records

Each record includes

Title, Type, Primary, Description, Pain point addressed, Use case, Source

Ideal customer profile2 records

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
Yes
API detail
Has APIbool
No

Docs URL, Description

AI maturity
App detail

Has app

Feature2 records

Each record includes

Title, Differentiator, Description, Source

Core technology
Revenue estimate
Valuation estimate
Number of profiles
Profiles2 records

Each record includes

Name, Designation, Designation category, Overview, Profile commentary, Source

No data
No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds1 record

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors1 record

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

BIA Separations

Bioprocessing Chromatography Consumablesbiaseparations.com

BIA Separations, a Sartorius company, develops and manufactures monolithic chromatography columns (CIMmultus) for downstream purification of AAV vectors, proteins, and viral vectors, serving gene therapy and biopharmaceutical manufacturers globally through direct enterprise sales.

What BIA Separations does

BIA Separations is a Slovenia-based developer and manufacturer of monolithic chromatography technology used in downstream purification of complex biological products. Founded in 1998 and headquartered in Ajdovščina with a second facility in Bled, the company operates under the Sartorius BIA Separations brand as part of the Sartorius Group, and employs 101–250 people. Its core product line is the CIMmultus family of Convective Interaction Media (CIM) monolithic chromatography columns, with CIMmultus QA HR positioned for scalable AAV capsid enrichment in gene therapy manufacturing, delivering documented performance of 88% ± 9% full capsid purity and 77% ± 3% genome recovery across scales from 1 mL to 8000 mL.

The company's technology is built on a proprietary monolithic stationary phase architecture that supports both bind-elute and flow-through operating modes, with an optimized step elution method that reduces process time relative to traditional linear-gradient approaches. Revenue is generated through direct enterprise sales of chromatography columns and consumables to gene therapy manufacturers (primary segment) and broader biopharmaceutical manufacturers producing proteins, vaccines, and viral vectors (secondary segment). Distribution is direct and global, leveraging Sartorius' bioprocessing sales infrastructure.

Complementing its product business, BIA Separations invests in scientific community-building activities, most notably the MSS (Monolith Summer School / bioprocessing symposium) series — with MSS2026 scheduled as a three-day event in Bled, Slovenia on September 14–16, 2026, combined with wet lab workshops at the Ajdovščina facility — functioning as both a customer-engagement and thought-leadership mechanism targeting the AAV/gene therapy and biologics manufacturing communities.

BIA Separations firmographics

Firmographics
Name
BIA Separations
Legal name
BIA Separations
Website
https://biaseparations.com
Company type
Private
Founded year
1998
Operating status
Operating
Headcount range
101–250 employees
Short description
BIA Separations, a Sartorius company, develops and manufactures monolithic chromatography columns (CIMmultus) for downstream purification of AAV vectors, proteins, and viral vectors, serving gene therapy and biopharmaceutical manufacturers globally through direct enterprise sales.
Ownership category
akta.pro rank

BIA Separations industry classification

Industry
Product category
Bioprocessing Chromatography Consumables
NAICS
Analytical Laboratory Instrument Manufacturing (334516)
SIC
Laboratory Analytical Instruments (3826)
akta.pro primary industry
Downstream Processing & Purification Technologies (chromatography, filtration, centrifugation) (HLAAAJAB)
akta.pro secondary industries
Bioprocess Consumables & Reagents (resins, membranes, media components, buffers) (HLAAAJAI), Analytical Instruments & Chromatography Systems (HLAGAIAA)

Keywords

  • Monolithic chromatography columns
  • Biopharmaceutical purification
  • Gene therapy manufacturing
  • Downstream bioprocessing
  • AAV vector purification

Where BIA Separations is headquartered

Location

Headquarters

HQ city
Ajdovscina
HQ country
Slovenia
HQ region
Europe

Offices2 records

Markets served

BIA Separations business model

Business model
GTM type
B2B
Offering type
Hardware or Manufacturing
Cost components
Personnel, Operations, Technology or R&D, Marketing or Sales

Revenue model

  1. Chromatography Products and Consumables: Sale of CIMmultus monolithic chromatography columns and related consumables for biopharmaceutical purification applications

Go-to-market motion2 records

Distribution channels1 record

Marketing channels1 record

BIA Separations product offering

Product offering

Core offering

BIA Separations develops, manufactures, and supplies CIMmultus monolithic chromatography columns, with the CIMmultus QA HR (high-resolution) line as a flagship product, for downstream purification of biological products including AAV vectors, viral vectors, and proteins. The columns are used by gene therapy manufacturers and biopharmaceutical manufacturers to capture, purify, and polish large biomolecules in industrial and clinical-scale bioprocessing workflows.

Product overview

BIA Separations, a Sartorius company, provides monolithic chromatography products for biopharmaceutical purification. The core product offering includes the CIMmultus QA HR line of monolithic chromatography columns designed for scalable AAV vector manufacturing and gene therapy production. The company also offers bioprocessing symposiums (MSS) and wet lab workshops as part of their customer engagement and training services.

Differentiator

Problem solved

Functional benefit

Brands

  • CIMmultus: Monolithic chromatography columns for biopharmaceutical purification including AAV vectors, proteins, and viral vectors.

Quantifiable outcome

  • 88% ± 9% full capsid purity achieved across scales from 1 mL to 8000 mL
  • +2 more outcomes

Companies that use BIA Separations

Customer profile

Segments2 records

Ideal customer profiles2 records

BIA Separations technology and API

Technology

Technology focussed Yes

API detail

Has API
No
API docs
API detail

Core technology

AI maturity

App detail

Feature2 records

BIA Separations partnerships and signals

Strategic signal

Partnerships

One partnership is on record.

  • Sartorius (as part of Sartorius BIA Separations)coreOthersBIA Separations operates under the Sartorius brand as Sartorius BIA Separations, indicating a subsidiary or integrated business unit relationship within the larger Sartorius Group, a global life science and bioprocessing company.

Scale indicators1 record

Recent moves4 records

Expansion highlights4 records

BIA Separations competitors and assessment

Company assessment

Emerging players

  • Avantor: Supplies bioprocessing consumables including chromatography resins, buffers, and single-use solutions to gene therapy and biologics manufacturers, with increasing focus on the viral vector purification workflow.
  • Asahi Kasei Medical (Planova): Provides virus filtration and select purification technologies used in biopharmaceutical manufacturing, overlapping with BIA's downstream processing solutions for viral vectors and biologics.

Broad incumbents

  • Sartorius AG: Parent/affiliated bioprocessing platform offering a broad portfolio of filtration, fermentation, and purification solutions. BIA operates within this portfolio, so Sartorius is both parent and broader incumbent competitor in adjacent bioprocessing categories.

Direct peers

  • Repligen: Specializes in bioprocessing solutions including OPUS pre-packed chromatography columns and filtration products used in gene therapy and biologics manufacturing — competing directly in downstream purification consumables.
  • Merck KGaA (MilliporeSigma): Provides a broad portfolio of chromatography resins, membrane adsorbers, and bioprocessing consumables for biologics and viral vector purification, directly competing in downstream processing.
  • Bio-Rad Laboratories: Supplies chromatography media, NGC systems, and process-scale columns for biopharmaceutical purification, overlapping with BIA's downstream purification offering for biologics and viral vectors.
  • Thermo Fisher Scientific: Through its Patheon and bioproduction units, offers POROS chromatography resins widely used for AAV and viral vector purification, positioning it as a primary alternative to BIA's monolithic columns.
  • Tosoh Bioscience: Manufactures chromatography resins (TOYOPEARL and TSKgel) used in biologics purification, including applications in gene therapy and vaccine manufacturing — a direct competitor in resin-based downstream processing.
  • Cytiva: Global bioprocessing leader offering ÄKTA chromatography systems and resin-based columns for downstream purification of biologics, viral vectors, and AAV — directly competing with BIA's monolithic offering in gene therapy and vaccine workflows.
  • Purolite (Ecolab Life Sciences): Manufactures chromatography resins including Praesto agarose-based resins targeted at AAV and biologics purification, positioning it as a direct competitor in process-scale downstream purification.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

BIA Separations social profiles

Digital presence

BIA Separations financial estimates

Financial estimate

Revenue estimate

Valuation estimate

BIA Separations leadership team

Management profile

Number of profiles

Profiles2 records

BIA Separations funding detail

Funding detail

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

BIA Separations M&A and investment

M&A and investment

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about BIA Separations

What does BIA Separations do?

BIA Separations develops, manufactures, and supplies CIMmultus monolithic chromatography columns, with the CIMmultus QA HR (high-resolution) line as a flagship product, for downstream purification of biological products including AAV vectors, viral vectors, and proteins. The columns are used by gene therapy manufacturers and biopharmaceutical manufacturers to capture, purify, and polish large biomolecules in industrial and clinical-scale bioprocessing workflows.

Is BIA Separations a public or private company?

BIA Separations is a private company. It is classified as corporate owned and is currently operating.

When was BIA Separations founded?

BIA Separations was founded in 1998. It employs 101 to 250 people.

Where is BIA Separations based?

BIA Separations is headquartered in Ajdovscina, Slovenia, in the Europe region.

How does BIA Separations make money?

One revenue line is on record: chromatography Products and Consumables.

Who are BIA Separations's main competitors?

Emerging players on record are Avantor and Asahi Kasei Medical (Planova). Sartorius AG is listed as a broad incumbent. Direct peers are Repligen, Merck KGaA (MilliporeSigma), Bio-Rad Laboratories, Thermo Fisher Scientific, Tosoh Bioscience, Cytiva and Purolite (Ecolab Life Sciences).

Does BIA Separations have an API?

No public API is recorded for BIA Separations.

What industry is BIA Separations in?

BIA Separations's product category is Bioprocessing Chromatography Consumables. Its primary akta.pro industry code is HLAAAJAB, Downstream Processing & Purification Technologies (chromatography, filtration, centrifugation), with a secondary code of HLAAAJAI, Bioprocess Consumables & Reagents (resins, membranes, media components, buffers). Its NAICS code is 334516 and its SIC code is 3826.

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Live signals
NatureOptimization and scale up strategies for reproducible AAV enrichment step on CIMmultus® QA HR lineResearchers demonstrated that CIMmultus QA HR monolithic chromatography columns from Sartorius BIA Separations enable reproducible AAV capsid enrichment, achieving 88% ± 9% full capsid purity with 77% ± 3% genome recovery across scales from 1 mL to 8000 mL. The optimized step elution method using bind-elute or flow-through modes provided comparable recovery and purity while improving scalability and reducing process time compared to traditional linear gradient methods. The findings offer a scalable, cost-effective solution for large-scale AAV vector manufacturing critical for gene therapy production.European Pharmaceutical ReviewBioprocessing symposium to showcase biopharma and purification innovationSartorius BIA Separations has organized a three-day bioprocessing symposium (MSS2026) scheduled for September 14-16, 2026 in Bled, Slovenia, focusing on biopharma and purification innovation for gene therapies, vaccines, and biological products. The event will feature three research streams covering nucleic acids and LNPs, proteins, and viruses/viral vectors, with additional Wet Lab Workshops on September 17-18 at the company's Ajdovščina facility. This is an industry networking and knowledge-sharing event for the biopharmaceutical sector.Business Wire BlogVector Purification Market Research, Industry Trends & Global Forecasts, 2035, Profiles of Agilent, BIA Separations, Bio-Rad, BioVision, Cytiva, Merck, Sartorius, Takara Bio, Thermo Fisher ScientificThe global vector purification market is valued at USD 155 million and is projected to grow at a CAGR of 21% from 2025 to 2035. Demand is driven by rising clinical trials for viral vector-based therapies, with adenoviruses accounting for over 40% of commercial demand. North America is the hub of development, and major players include Bio-Rad, Cytiva, and Thermo Fisher.PR NewswireEC Mergers & Acquisitions advised BIA Separations on its Sale to SartoriusEC Mergers & Acquisitions announced the completion of BIA Separations' sale to the Sartorius Group on November 2, 2020. The transaction valued at €360 million consisted of €240 million in cash and €120 million in Sartorius Stedim Biotech shares, with additional earn-out payments tied to five-year performance targets. BIA Separations, a Slovenian purification specialist developing products for large biomolecule purification used in cell and gene therapies, is forecasted to generate approximately €25 million in revenue for 2020.PR NewswireSartorius Stedim Biotech closes acquisition of BIA SeparationsSartorius Stedim Biotech successfully closed its acquisition of Slovenian purification specialist BIA Separations on November 2, 2020, for a total purchase price of 360 million euros (240 million in cash and 120 million in SSB shares), with additional earn-out payments tied to future performance over five years. BIA Separations develops and manufactures market-leading products for purification and analysis of large biomolecules used in cell and gene therapies, and is expected to generate approximately 25 million euros in sales in 2020 with profit margins accretive to SSB's EBITDA. The acquisition adds 120 employees and is expected to accelerate SSB's offering in manufacturing gene therapies and other advanced therapies.PR NewswireSartorius closes acquisition of BIA SeparationsSartorius successfully closed its acquisition of Slovenian purification specialist BIA Separations on November 2, 2020, for a total consideration of 360 million euros (240 million in cash and 120 million in Sartorius Stedim Biotech shares), plus performance-based earn-out payments over five years. BIA Separations develops market-leading products for purification of large biomolecules used in cell and gene therapies, with forecasted 2020 sales of approximately 25 million euros and 120 employees joining Sartorius. The transaction, intended to strengthen Sartorius's offering in advanced therapy manufacturing, is not expected to have a material impact on the company's 2020 results.PR NewswirePurification specialist BIA Separations to become part of SartoriusSartorius announced a definitive agreement to acquire purification specialist BIA Separations in a transaction valued at 360 million euros, with the deal expected to close in late 2020. The acquisition integrates BIA into Sartorius Stedim Biotech to create a center of excellence for cell and gene therapy purification, leveraging BIA's CIM monolith chromatography technology. Both companies anticipate significant growth, with BIA forecasted to generate approximately 25 million euros in sales revenue for 2020.PR NewswirePurification specialist BIA Separations to become part of Sartorius Stedim BiotechSartorius Stedim Biotech announced it has entered into a definitive agreement to merge with purification specialist BIA Separations in a transaction totaling 360 million euros (240 million in cash and 120 million in shares), with additional earn-out payments based on performance over five years. BIA Separations, a Slovenian company founded in 1998, develops and manufactures market-leading products for purification and analysis of large biomolecules used in cell and gene therapies, and is forecasted to earn approximately 25 million euros in sales revenue in 2020. The transaction, expected to close in late 2020 pending regulatory approval, aims to create a premium portfolio for advanced therapies with BIA serving as Sartorius Stedim Biotech's center of excellence for purification.