Guna

What Guna does

Guna S.p.a. is a privately held Italian pharmaceutical company founded in 1983 in Milan by Alessandro Pizzoccaro and Adriana Carluccio, specializing in low-dose homeopathic medicines and class III injectable collagen medical devices. Its core technology is SKA (Sequential Kinetic Activation), a proprietary platform that standardizes the dilution and dynamization process per European Pharmacopoeia standards to produce nano-concentration formulations containing cytokines, hormones, neuropeptides, and growth factors grounded in Psycho-Neuro-Endocrine-Immunology (PNEI) principles. Manufacturing is concentrated in a 64,500+ sq ft GMP-certified facility in Milan (opened 2008) that produces oral medicines (granules, globules, drops, oral sprays, syrups), nasal sprays, and injectable collagen medical devices across seven product categories: Low Dose Medicines, Medical Devices (13 CE-marked class III collagen injectables), Food Supplements/Nutraceuticals, Bach Flowers (with proprietary WHITE Holographic Bioresonance processing), Dermocosmetics, Guna4Pets (animal feed supplements), and Publications (Guna Editore).

The business model is a hybrid B2B/B2C distribution system: in Italy, products flow through the pharmacy network and a field force of pharmaceutical representatives and pharmacy consultants conducting medical detailing to doctors and pharmacists, supplemented by hundreds of educational events annually; internationally, Guna distributes through exclusive local distributors in 50+ countries and operates a wholly-owned US subsidiary (Guna Inc.). Guna also acts as the exclusive Italian distributor for Heel (homotoxicology), Labo'Life (micro-immunotherapy), and Enterosgel. Revenue streams span the seven product categories plus exclusive third-party distribution; pricing is not publicly disclosed but operates on B2B terms through pharmacy and professional channels. The company holds 35% share of the Italian homeopathy market, is self-funded without external equity, and operates under an explicit 'No Patent' policy with copyleft-licensed publications, distinguishing it from typical pharmaceutical IP strategies.

Name

Guna

Legal name

Guna S.p.a.

Website

https://guna.com

Company type

Private

Founded year

1983

Operating status

Operating

Headcount range

251–500 employees

Short description

Guna is a privately held Italian pharmaceutical company founded in 1983 in Milan, producing low-dose homeopathic medicines and class III injectable collagen medical devices via proprietary SKA technology, distributed through pharmacies, physicians, and exclusive partners in 50+ countries.

Ownership category

akta.pro rank

Product category

Homeopathic Pharmaceutical Manufacturing

NAICS

Pharmaceutical Preparation Manufacturing (325412), Surgical and Medical Instrument Manufacturing (339112)

SIC

Pharmaceutical Preparations (2834), Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Primary Care & General Medicine Pharmaceuticals (HLAIAAAA)

akta.pro secondary industries

Dermatology & Aesthetics Pharmaceuticals (HLAIAAAK), Dermatology Specialty Pharmaceuticals (HLAIACAL)

Keywords

• Low-dose medicines
• Homeopathic pharmaceuticals
• Collagen medical devices
• Physiological nutraceuticals
• Pharmaceutical manufacturing

Headquarters

HQ city

Milan

HQ country

Italy

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Operations, Personnel, Technology or R&D, Marketing or Sales, Supply Chain, Infrastructure

Revenue model

1. Low Dose Medicines: Production and distribution of homeopathic and low-dose pharmacological medicines including granules, globules, drops, oral sprays, syrups, and nasal sprays. Core business segment with over 40 years of market presence.
2. Medical Devices: CE certified injectable collagen medical devices (class III) for musculoskeletal and aesthetic medicine applications. Includes MD-Knee, MD-Tissue, GUNA Collagen MDs product lines.
3. Food Supplements (Nutraceuticals): Physiological nutraceuticals including vitamins, minerals, probiotics, botanical extracts, and specialized formulations for various health needs including digestive health, immune support, and metabolic function.
4. Bach Flowers: 38 Bach Flower remedies prepared according to Dr. Bach's Original Method, certified B.A.F.E.P., with WHITE Holographic Bioresonance processing.
5. Dermocosmetics: High-quality natural ingredient-based dermocosmetics with derma-restorative, regenerative, and rebalancing properties for sensitive and irritated skin.
6. Pet Products (Feed Supplements): Guna4Pets line of complementary feeds for dogs and cats supporting daily nutritional needs and maintenance of normal physiological conditions.
7. Publishing: Guna Editore publishes 'La Medicina Biologica' journal and over 50 original texts on complementary medicine topics since 1983.

Pricing tiers

Go-to-market motion3 records

Distribution channels6 records

Marketing channels8 records

Core offering

Guna manufactures and distributes low-dose homeopathic medicines, injectable collagen medical devices (Class III), food supplements, Bach flowers, dermocosmetics, and pet nutritional supplements from its pharmaceutical factory in Milan, Italy. The company uses its proprietary SKA (Sequential Kinetic Activation) technology to produce physiological formulations based on Psycho-Neuro-Endocrine-Immunology (PNEI) principles, and distributes its own products plus third-party brands (Heel, Labo'Life, Enterosgel) to over 50 countries through pharmacies and exclusive distributors.

Product overview

Guna is an Italian pharmaceutical company founded in 1983 specializing in low-dose medicine and physiological health products. Its portfolio includes Low Dose Medicine (homeopathic formulations using SKA technology with cytokines, hormones, and neuropeptides), Guna Collagen Medical Devices (13 injectable class III medical devices for pain treatment), Food Supplements (nutraceuticals including probiotics, iron supplements, and botanical formulations), Dermocosmetics (natural skincare), Bach Flowers (emotional therapy preparations), Guna4Pets (animal health supplements), and Publications. The company also distributes third-party brands including Heel (homotoxicology), Labo'Life (micro-immunotherapy), and Enterosgel in Italy. Products are available in over 50 countries through exclusive distributors, with operations in the US under Guna Inc.

Differentiator

Problem solved

Functional benefit

Brands

• Guna4Pets: Complementary feeds (pet food supplements) for dogs and cats of all ages contributing to daily nutritional needs and maintenance of normal physiological conditions of animal friends.
• Guna Collagen Medical Device
• Guna Editore

Products and services

• Low Dose Medicine Homeopathic medicines utilizing low doses of active ingredients derived from plant, mineral, and animal origins, produced via proprietary SKA (Sequential Kinetic Activation) technology. Products include cytokines, hormones, neuropeptides, and growth factors in physiological concentrations for restoring body equilibrium, prescribed by healthcare practitioners for chronic conditions and preventive medicine.
• Guna Collagen Medical Devices Range of 13 Class III CE-marked injectable medical devices containing porcine collagen, indicated for osteo-arthro-myofascial pain treatment and aesthetic medicine applications. Includes MD-Knee, MD-Tissue, MD-Lumbar, MD-Muscle, MD-Neural, and other device variants sold through medical professionals.
• Food Supplements (Nutraceuticals) Physiological nutraceuticals including Proflora (probiotic), Ferroguna (iron supplement), Colostrononi (bovine colostrum), Omega-formula, Epadoguna (liver supplement), and various vitamin and mineral formulations. Sold through pharmacies for consumer health and wellbeing.
• Bach Flowers 38 Bach Flower essence preparations based on Dr. Edward Bach's original method, processed using WHITE Holographic Bioresonance technology for emotional state rebalancing. Includes single remedies and compound formulations distributed through pharmacies for consumer emotional wellness.
• Dermocosmetics Skincare products formulated with natural ingredients including Arnica, Bisabolol, Geranium, Lavender, Neem oil, Peppermint, Tamanu, Tea Tree Oil, and White waterlily for sensitive and irritated skin of face and body. Distributed through pharmacies as part of Guna's product portfolio.
• Guna4Pets (Petformula) Complementary feed supplements for dogs and cats including pastes supporting daily nutritional needs, relaxation, joints, cognitive function, and renal function. Sold through veterinary channels and pharmacies for pet owners seeking natural health support.
• Publications (Guna Editore) Editorial division publishing 'La Medicina Biologica' journal and over 50 original texts on complementary medicine topics including homeopathy, homotoxicology, flower therapy, and biological medicine. Publications carry copyleft license for free distribution.
• Enterosgel (Distributed Product) Intestinal adsorbent medical device distributed in Italy on behalf of Asure Pharma under Bioline license. CE0123 certified product indicated for symptomatic treatment of diarrhea, sold through Italian pharmacy channel.
• Heel Products (Distributed) Homotoxicology medicines distributed exclusively in Italy from Heel, the largest German homotoxicology pharmaceutical company founded by H. H. Reckeweg. Products follow Reckeweg's pathophysiological approach to medicine.
• Labo'Life Products (Distributed) Micro-immunotherapy products developed by Labo'Life (founded in France 1992 by Christian Foissey), distributed exclusively in Italy by Guna. Products focus on optimizing natural immune processes and promoting regulation and self-healing mechanisms.

Quantifiable outcome

• 35% market share in Italian homeopathy sector
• +4 more outcomes

Named customers6 records

Segments4 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

Eleven partnerships are on record, tiered minor and core.

• Zero Impact / LifeGateminorOthers · 1 January 2008Since 2008, Guna participates in Zero Impact LifeGate project that calculates, reduces, and offsets CO2 emissions from activities, products, services and events. Partnership helps create and protect forests in Costa Rica as part of Guna's environmental sustainability commitment.
• HeelcoreChannel Partner/ Reseller/ DistributorHeel is the largest German homotoxicology pharmaceutical company, founded by H. H. Reckeweg who developed the discipline. Guna is the exclusive distributor of Heel products in Italy. Heel produces homotoxicological medicines following Reckeweg's pathophysiological approach.
• Labo'LifecoreChannel Partner/ Reseller/ DistributorFounded in France in 1992 by Christian Foissey, Labo'Life specializes in micro-immunotherapy. Guna is the exclusive distributor of Labo'Life products in Italy. The company focuses on optimizing natural immune processes and promoting regulation and self-healing mechanisms.
• Asure Pharma (Enterosgel)minorChannel Partner/ Reseller/ DistributorAsure Pharma distributes Enterosgel in Europe under Bioline license. Guna distributes Enterosgel in Italy as a CE0123 medical device for gastrointestinal applications, backed by extensive scientific documentation.
• Italian National Health Institute (Istituto Superiore di Sanita)coreStrategic or Co-development PartnerCollaborative research partner conducting basic and clinical research together with Italian and international universities and public entities. Research focus includes low-dose medicines and physiological regulating medicine.
• Fatebenefratelli Hospital, RomecoreStrategic or Co-development PartnerCollaborative research partner in clinical studies on low-dose medicine applications and physiological regulating medicine approaches.
• La Sapienza University, RomecoreStrategic or Co-development PartnerAcademic research collaboration partner conducting basic and clinical research in low-dose pharmacology and physiological medicine.
• International Academy of Physiological Regulating MedicinecoreStrategic or Co-development PartnerProfessional medical academy with which Guna collaborates on research and education in physiological regulating medicine. Part of the permanent scientific committee coordinated by Guna's medical-scientific direction.
• Medical AssociationscoreStrategic or Co-development PartnerPartnerships with medical associations for organizing educational events, seminars, courses, and multi-year schools for doctors. Guna collaborates with associations dedicated to teaching complementary medicine disciplines.
• Pharmacy AssociationscoreStrategic or Co-development PartnerPartnerships with pharmacy associations for organizing educational programs and training for pharmacists on low-dose medicines and nutraceuticals.
• International Distributors NetworkcoreChannel Partner/ Reseller/ DistributorExclusive distributors in over 50 countries including: Africa (Egypt, South Africa), Asia/Middle East (Azerbaijan, Georgia, Israel, Jordan, Palestine, Thailand, Vietnam), Europe (Albania, Bulgaria, Croatia, Cyprus, Czech Republic, Greece, Hungary, Ireland, Latvia, Lithuania, Macedonia, Malta, Moldova, Montenegro, Poland, Portugal, Romania, Russia, Slovakia, Slovenia, Spain, Switzerland, Turkey, Ukraine, UK), North America (USA via Guna Inc), Latin America (Bolivia, Chile, Colombia, Ecuador, Guatemala, Peru).

Scale indicators6 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Boiron: Boiron is the global leader in homeopathic medicines, headquartered in France. Directly competes with Guna in low-dose and homeopathic product categories across overlapping European and international pharmacy channels, serving the same doctors and pharmacists.
• Biologische Heilmittel Heel: Heel is Germany's leading homotoxicology pharmaceutical company and the originator of Reckeweg's homotoxicology approach. Heel is both a direct competitor in low-dose medicines and a distribution partner whose products Guna distributes exclusively in Italy, making it a close comparable on product, manufacturing, and channel.
• Labo'Life: Labo'Life is a French pharmaceutical company specializing in micro-immunotherapy, founded in 1992. It is both a direct peer in low-dose immunological preparations and a distribution partner distributed exclusively by Guna in Italy, sharing overlapping physician-customer segments and a similar low-dose regulatory pathway.
• Weleda: Weleda is a Swiss-founded manufacturer of anthroposophic and natural medicines, dermocosmetics, and food supplements. Directly comparable to Guna across low-dose medicines, natural skincare, and homeopathic-style formulations, with global pharmacy and practitioner distribution.
• WALA Heilmittel: WALA is a German manufacturer of anthroposophic medicines, natural cosmetics, and holistic remedies. Comparable to Guna in low-dose / potentized pharmaceutical preparations, GMP manufacturing, and practitioner-channel distribution in Europe and select international markets.
• Deutsche Homöopathie-Union (DHU): DHU is the largest German manufacturer of homeopathic medicines, producing a broad range of single remedies and complex preparations. Directly competes with Guna in pharmacy-distributed homeopathic formulations and shares similar European regulatory pathway and practitioner-customer base.
• Schwabe Group: Schwabe is one of the world's largest producers of plant-based and homeopathic pharmaceuticals, headquartered in Germany. Comparable to Guna in low-dose and phytopharmaceutical manufacturing, global pharmacy distribution, and clinical research in botanical medicine.
• A. Vogel (Bioforce): A. Vogel is a Swiss herbal medicine manufacturer producing plant-based pharmaceutical preparations, tinctures, and food supplements. Overlaps with Guna's nutraceutical and natural-medicine lines and shares the European pharmacy distribution model targeting health-conscious consumers.
• Hyland's: Hyland's is a leading US-based homeopathic medicines manufacturer. Directly comparable to Guna in homeopathic product formats, OTC pharmacy distribution, and category leadership, particularly relevant as Guna's US subsidiary (Guna Inc.) competes in the same channel.

Emerging players

• Genexa: Genexa is a US-based homeopathic and clean-label OTC medicines company targeting modern health-conscious consumers. An emerging peer to Guna's homeopathic franchise, sharing the pharmacy/retail channel and increasingly overlapping in clean-label positioning of OTC homeopathic remedies.

Market position

Competitive moat6 records

Key risks5 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/user/GUNATV
• Facebookfacebook.com/guna.spa
• LinkedInlinkedin.com/company/gunaspa
• Instagraminstagram.com/guna_it

Compliance6 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Subsidiaries1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Guna