What PendoTECH does

Mettler-Toledo Pendotech is a Princeton, New Jersey-based designer and manufacturer of single-use in-line sensors and process control systems for biopharmaceutical manufacturing. Founded in 2005 and operating as a wholly-owned business unit of Mettler Toledo (NYSE: MTD), the company sells a vertically integrated portfolio spanning single-use pressure, temperature, conductivity, pH, UV absorbance, turbidity, and flow sensors; companion transmitters and monitors including the PressureMAT family, PM2 dual-wavelength photometer, and Pendotech DAQ; and complete automation systems for normal-flow filter screening, tangential flow filtration (TFF), and virus/depth filtration. Core sensing technologies include proprietary MEMS-HAP™ high-accuracy pressure chips, electrochemical pH probes, UV LED photometry, piezoelectric ultrasonic flow measurement, and thermistor-based temperature sensing, with all fluid-contact materials meeting USP Class VI and manufacturing conducted in ISO 9001- and ISO 13485-certified clean rooms.

The company targets four primary customer segments: biopharmaceutical manufacturers producing monoclonal antibodies, recombinant proteins, vaccines, and viral vectors; process development and pilot plant teams running filter sizing and scale-up studies; contract development and manufacturing organizations (CDMOs) requiring rapid campaign changeover; and emerging cell and gene therapy manufacturers needing real-time process analytical technology. PendoTECH monetizes exclusively through hardware sales (sensors, monitors, control systems) and a complementary service revenue stream covering on-site repair, calibration, recertification, IQ/OQ documentation, and training. All sales are quote-based and consultative, conducted through direct engagement (phone, email, website forms) and an OEM portal for system integrators. Pricing is not publicly disclosed. PendoTECH's go-to-market relies on technical content marketing, industry conference participation, webinars, and a deep certified-integration footprint with pump and scale vendors including Masterflex, Watson Marlow, QuattroFlow, Levitronix, Sartorius, Ohaus, and intra-parent Mettler Toledo scale lines.

Name

PendoTECH

Legal name

Mettler-Toledo Pendotech

Website

https://pendotech.com

Company type

Private

Founded year

2005

Operating status

Operating

Headcount range

1–10 employees

Short description

PendoTECH designs and manufactures single-use in-line sensors and integrated process control systems for biopharmaceutical manufacturers, serving process development labs, GMP production facilities, CDMOs, and cell/gene therapy manufacturers globally.

Ownership category

akta.pro rank

Product category

Bioprocess Sensors and Process Control Systems

NAICS

Analytical Laboratory Instrument Manufacturing (334516), Other Measuring and Controlling Device Manufacturing (334519), Totalizing Fluid Meter and Counting Device Manufacturing (334514)

SIC

Laboratory Analytical Instruments (3826), Totalizing Fluid Meters & Counting Devices (3824)

akta.pro primary industry

Process Analytical Technology (PAT) & In-Line/At-Line Analytics (spectroscopy, sensors, monitoring) (HLAAAJAD)

akta.pro secondary industries

Bioprocess Safety, Biosafety & Contamination Control Solutions (single-use integrity, environmental monitoring) (HLAAAJAO), Automation, Controls & Manufacturing Execution for Bioprocessing (SCADA/DCS/PLC/MES) (HLAAAJAE), Viral Clearance, Sterile Filtration & Bioburden Control Technologies (HLAAAJAL)

Keywords

• Bioprocess sensors
• Single-use pressure sensors
• Pharmaceutical process monitoring
• Filtration control systems
• Biomanufacturing analytics

Headquarters

HQ city

Princeton

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Personnel, Technology or R&D, Operations, Marketing or Sales

Revenue model

1. Single-Use Sensors and Monitors: PendoTECH sells single-use and reusable in-line sensors including pressure sensors, temperature sensors, conductivity sensors, pH sensors, UV/turbidity flow cells, flow meters, and air-in-tube detectors. Sensors are sold alongside compatible transmitters, monitors, and data acquisition systems. Products serve biopharmaceutical manufacturers across process development, pilot, and GMP production scales.
2. Process Control Systems: Complete process automation and data acquisition solutions including the TFF Process Control System, Normal Flow Filter Screening System (NFF), and Virus-Depth Filtration System. These systems integrate sensors, pumps, scales, and valves under graphical user interface control for automated bioprocess monitoring and control.
3. Data Acquisition Software: Pendotech DAQ software provides real-time process trending, centralized sensor visibility, automated data collection, electronic process notes, and Excel-compatible data export. Sold as part of hardware systems or as standalone software with PMAT GUI data acquisition package.
4. Service, Calibration, and Recertification: PendoTECH offers product service, on-site repair, calibration, configuration, installation, maintenance, qualifications, and training through service care packages. The company maintains Service Repair Centers and offers on-site service requests, recertification of equipment, and IQ/OQ template documentation.

Go-to-market motion1 record

Distribution channels2 records

Marketing channels7 records

Core offering

PendoTECH designs, manufactures, and sells single-use in-line sensors (pressure, temperature, conductivity, pH, UV absorbance, turbidity, and flow) along with compatible transmitters, monitors, and integrated data acquisition systems for biopharmaceutical manufacturing. The company also offers automated process control systems for tangential flow filtration (TFF), normal flow filtration (NFF), and virus-depth filtration, complemented by calibration, recertification, installation, and training services for bioprocessing customers.

Product overview

Mettler-Toledo Pendotech offers a modular biopharmaceutical process monitoring and control platform centered on single-use in-line sensors and integrated control systems. The product portfolio spans three interconnected layers: (1) a broad suite of single-use sensors for measuring pressure (Single-Use Pressure Sensors), UV absorbance, turbidity, temperature, conductivity, and pH; (2) transmitters and monitors (PressureMAT, CMONT, PM2 Photometer, TT1, and Pendotech DAQ) that collect sensor data and provide real-time monitoring, alarming, and data acquisition; and (3) automated process control systems (Filter Screening System/NFF, Cross Flow Filtration TFF System, and Virus-Depth Filtration System) that integrate sensors, pumps, and scales for complete filtration process automation. Supporting products include flow meters (rotary, ultrasonic/LEVIFLOW, and Coriolis), an ultrasonic air-in-tube detector, tubing throttle valve for flow/pressure control, and lab scale process vessels. The system architecture is unified through Pendotech DAQ, which centralizes data from up to 14 devices, and through the PressureMAT monitor family (including PLUS and DPG handheld variants) which serves as the primary interface for single-use pressure sensor monitoring. All products are designed for the biopharmaceutical manufacturing industry and meet USP Class VI standards.

Differentiator

Problem solved

Functional benefit

Products and services

• Single-Use Pressure Sensors MEMS-based single-use pressure sensors measuring static and dynamic pressure of gases and liquids in biopharmaceutical processes, rated for use up to 75 psi, built with USP Class VI materials, and compatible with gamma and x-ray irradiation. Sold to biopharmaceutical manufacturers for filtration, chromatography, bioreactor, and fill/finish pressure monitoring.
• PressureMAT Sensor Monitor and Transmitter All-in-one monitor, alarm, and transmitter unit for real-time pressure monitoring of PendoTECH Single-Use Pressure Sensors, with LCD display, configurable alarm limits, and 4-20 mA/RS-232 output for process control integration. Aimed at biopharmaceutical and process development teams.
• Pressure Sensor Transmitter (PTR) Transmitter device connecting to PendoTECH pressure sensors to produce a 4-20 mA signal linear with pressure, with enhanced accuracy, quick response time, Modbus TCP programming support, and relay output, compliant with CE, UKCA, UL, cUL, RoHS, and REACH standards. For bioprocess control system integrators.
• In-Line UV Absorbance Sensors (UV Flow Cells) Single-use UV flow cells with PM2 photometer enabling non-invasive UV absorbance measurements at 280 nm (typical) for protein detection in filtration and chromatography applications, with unobstructed flow path and USP Class VI materials.
• PM2 Photometer Dual-wavelength UV/Vis photometer equipped with two LED light sources, configurable for wavelengths including 260nm, 280nm, 300nm, and 880nm, supporting simultaneous dual-wavelength measurements for protein/nucleic acid detection and turbidity monitoring. Sold to biopharmaceutical process development and manufacturing teams.
• Single-Use Temperature Sensors Calibration-free thermistor-based single-use temperature sensors measuring 0-70 degrees C with better than plus/minus 0.2 degrees C accuracy (typically plus/minus 0.1 degrees C), available with hose barb or luer fittings, gamma irradiation compatible. For bioreactor and chromatography temperature monitoring.
• Single-Use Conductivity Sensors Single-use conductivity sensors with pre-determined cell constant, measuring conductivity range 0.1 to 100 mS/cm with no calibration required, gamma compatible up to 50 kGy, NaOH resistant, and USP Class VI compliant. Used for buffer composition verification in bioprocessing.
• Single-Use pH Sensors Electrochemical single-use pH probes for real-time in-line pH monitoring in downstream bioprocessing, GMP-ready, gamma irradiation compatible, designed to capture rapid pH shifts during chromatography, TFF, UF/DF, and buffer preparation. Sold to biopharmaceutical manufacturers and CDMOs.
• Single-Use Ultrasonic Flow Meters (LEVIFLOW) LEVIFLOW single-use ultrasonic flow meters using DSP technology for bubble-robust flow measurement with high 1% precision, featuring no moving parts to prevent particle generation, gamma-sterilizable polypropylene fluid path, and biocompatible materials meeting FDA, USP-VI, BSE/TSE, and Animal Free standards.
• Ultrasonic Air in Tube Detector Non-invasive ultrasonic detector identifying air or liquid presence in tubes, compatible with all tube types, integrates into control systems for chromatography, depth filtration, TFF, and bioreactor applications, with digital 5V output and optional pump shut-off integration.
• Pendotech DAQ (Data Acquisition System) Centralized bioprocess monitoring platform supporting up to 14 device inputs including 4 pressure sensors, 2 flow meters, 1 pH probe, 1 conductivity electrode, 1 air detector, 2 scales, and 3 configurable analog inputs, with real-time trending, automated data logging to CSV, and alarm management. Sold to bioprocess development and manufacturing teams.
• Filter Screening System (NFF) Normal flow filtration system for filter sizing and optimization studies, monitoring up to 4 filter trains with 3 pressure sensors each (12 total) simultaneously for comparative filtration studies, with real-time trending, alarm management, and CSV data export. Sold to process development and pilot plant teams.
• Cross Flow Filtration TFF System Tangential flow filtration process control system with recipe-based automation for concentration and diafiltration processes, featuring TMP and Delta-P calculations, automated diafiltration endpoint options (weight, conductivity, pH, air detection, total flow), and integration with industry-standard pumps and scales.
• Virus-Depth Filtration System Process control and data acquisition system for virus filtration and depth filtration operations, with preprogrammed process step functions including prefilter flush, product filtration with air detector or scale endpoint, recovery, and automated pump shutdown on alarm conditions. Sold to biomanufacturers and CDMOs.

Segments4 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration21 records

Feature8 records

Partnerships

One partnership is on record.

• Mettler ToledocoreOthersPendoTECH is a business unit and brand under Mettler Toledo, operating as Mettler-Toledo Pendotech. Mettler Toledo is a global provider of precision instruments and services. The PendoTECH brand is integrated under Mettler Toledo's process analytics division, benefiting from the parent company's global sales network, R&D capabilities, and brand reputation in the life sciences instrumentation market.

Scale indicators3 records

Recent moves1 record

Expansion highlights5 records

Broad incumbents

• Sartorius AG: Sartorius is a major bioprocess equipment incumbent offering single-use bioreactors, filtration, sensors and PAT solutions. While broader in scope, Sartorius competes with PendoTECH in integrated upstream/downstream process monitoring and in OEM sensor partnerships.
• Merck KGaA / MilliporeSigma: MilliporeSigma is a leading supplier of bioprocess filtration, single-use assemblies and process monitoring solutions. Its Mobius single-use platform overlaps with PendoTECH's filtration and downstream process monitoring portfolio across biopharmaceutical manufacturers.
• Cytiva (Danaher): Cytiva (owned by Danaher) is a large incumbent bioprocess solutions provider offering single-use filtration, chromatography, sensors and integrated control systems. While much broader than PendoTECH, Cytiva competes in many of the same downstream filtration and chromatography process monitoring use cases.
• Thermo Fisher Scientific (Life Sciences / PAT): Thermo Fisher's life sciences and PAT portfolio spans laboratory analytical instruments, bioprocess sensors and integrated process analytics. As a broad life science incumbent, Thermo Fisher competes with PendoTECH in laboratory and bioprocess measurement, particularly for process development customers.

Direct peers

• Repligen Corporation: Repligen develops single-use bioprocess technologies including flow meters, sensors and filtration systems for biologics manufacturing. It is a closely comparable competitor in single-use flow measurement and process analytics, directly targeting similar biopharmaceutical process development customers.
• Hamilton Company: Hamilton is one of the closest direct competitors in single-use in-line sensors for bioprocess monitoring, with overlapping single-use pH, dissolved oxygen, conductivity and optical sensors. PendoTECH competes head-to-head with Hamilton across biopharmaceutical process analytical technology (PAT) applications.
• Levitronix: Levitronix manufactures single-use ultrasonic flow meters (PuraLev) and pump/flow control systems used in bioprocessing. Levitronix is both a supplier to PendoTECH (LEVIFLOW integration) and a direct competitor in single-use flow measurement for upstream and downstream bioprocess.
• Parker Hannifin (domnick hunter / Life Sciences): Parker's domnick hunter / Life Sciences division manufactures single-use filtration and process sensor solutions for biopharma, directly overlapping with PendoTECH's filtration-focused pressure sensors and control systems. Parker is a meaningful competitor in sterile filtration and process analytics.

Emerging players

• Broadley-James Corporation: Broadley-James manufactures single-use and re-usable pH, dissolved oxygen and other bioprocess sensors. It is a niche competitor in single-use electrochemical sensors for bioprocess applications that directly competes with PendoTECH's pH sensor line.
• ABEC (Custom Biogenic Systems): ABEC designs single-use process solutions including bioreactors and filtration systems for biopharmaceutical manufacturers. It overlaps with PendoTECH in downstream process monitoring and increasingly competes for integrated single-use workflow budgets.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks5 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/pendotech
• Xx.com/PendoTec

Compliance10 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about PendoTECH