C8 Sciences

What C8 Sciences does

C8 Sciences is a privately held, New Haven-based cognitive training company that commercializes 20+ years of neuroscience research conducted at Yale University by founder Bruce E. Wexler, M.D. Its two flagship products, ACTIVATE™ for children and REJUVENATE™ for adults, deliver neuroscience-based cognitive training that combines six adaptive computer games with a physical exercise program (100+ activities) to strengthen the brain's eight core cognitive capacities, including sustained attention, working memory, response inhibition, and cognitive flexibility. The platform incorporates NIH Toolbox-aligned assessments (Flanker, Working Memory, Go/No-Go, and Balloon Analog Risk Task) and collects real-time interaction data to generate progress reporting for parents, teachers, and clinicians.

The company operates a hybrid go-to-market model. Direct-to-consumer subscriptions are sold self-serve through the website at $19.99 per month to $169.99 per year for ACTIVATE and $22.99 per month to $169.99 per year for REJUVENATE, with a 30-day money-back guarantee and a free mini-trial funnel. A separate school and district channel sells volume licensing through a quote-based portal that includes teacher dashboards, professional development, and administrative reporting. The company also pursues healthcare provider channels for clinical deployment. COPPA, FERPA, and CIPA-aligned compliance certifications support procurement by K-12 institutions, and an NIH-funded clinical study reporting that 53% of children with ADD/ADHD significantly improved self-management provides third-party validation for sales conversations.

C8 Sciences is a small organization with 1–10 employees, no disclosed venture capital beyond a 2012 seed round of $320,000 from Connecticut Innovations and LaunchCapital, and no disclosed revenue. Products are not FDA-cleared and are positioned as complements to, not substitutes for, ADHD and depression medications. Customer evidence is anchored by named deployments such as PS316 (an NYC Public School) and a Brooklyn, NY principal who reported a one-grade-level reading improvement after eight weeks of use, alongside extensive testimonials from parents, teachers, and administrators.

Name

C8 Sciences

Legal name

C8 Sciences

Website

https://c8sciences.com

Company type

Private

Founded year

2011

Operating status

Operating

Headcount range

1–10 employees

Short description

C8 Sciences commercializes Yale neuroscience research into ACTIVATE™ and REJUVENATE™, subscription-based cognitive training platforms for children and adults that combine adaptive computer games with physical exercises to improve attention, memory, and executive function.

Ownership category

akta.pro rank

Product category

Educational / Cognitive Training Software

NAICS

Software Publishers (5132), Educational Support Services (611710)

SIC

Services-Prepackaged Software (7372), Services-Educational Services (8200)

akta.pro primary industry

Executive Functioning & Behavioral Support Tools (ADHD, SEL/Behavior Tracking, Routines) (EDAFAKAG)

akta.pro secondary industries

Virtual Special Education & Related Services (IEP Delivery Online) (EDAJADAG), Cognitive Stimulation & Reminiscence Therapy (Non-Clinical) (HSABAEAH), Adaptive Learning & Personalized Instruction Software (EDAJAMAE)

Keywords

• Cognitive training software
• Child brain development
• ADHD learning program
• Adult brain health
• Neuroscience education platform

Headquarters

HQ city

New Haven

HQ country

United States

HQ region

North America

Markets served

GTM type

B2B and B2C

Offering type

Software

Cost components

Technology or R&D, Marketing or Sales, Personnel, Operations, Infrastructure

Revenue model

1. ACTIVATE Home Subscription: Direct-to-consumer subscription model for parents to access cognitive training for children. Monthly, quarterly, and annual subscription tiers provide full access to the computerized games, physical exercise program, and cognitive assessments with real-time reporting.
2. REJUVENATE Subscription: Subscription-based cognitive training for adults targeting brain health, mood improvement, and anxiety reduction. Offers 1-month, 3-month, and annual subscription plans with comprehensive cognitive assessments and personalized training.
3. ACTIVATE School/Education Licensing: Volume licensing model for schools and educational institutions. Schools purchase licenses for multiple students with additional teacher dashboard features, professional development resources, and administrative reporting tools. Pricing based on number of licenses.

Pricing tiers

Go-to-market motion2 records

Distribution channels4 records

Marketing channels5 records

Core offering

C8 Sciences develops and sells neuroscience-based cognitive training software products—ACTIVATE™ for children and REJUVENATE™ for adults—delivered as subscription-based online programs that combine adaptive computerized cognitive exercises (targeting 8 Core Cognitive Capacities such as attention, working memory, and cognitive flexibility) with built-in NIH Toolbox-aligned assessments and a complementary physical exercise program. The company sells both direct-to-consumer home subscriptions and quote-based volume licenses to K-12 schools.

Product overview

C8 Sciences offers two primary cognitive training products: ACTIVATE™ for children and REJUVENATE™ for adults. ACTIVATE™ is a comprehensive cognitive cross-training program that combines neuroscience-based computer games (6 games with hundreds of difficulty levels) with a physical exercise program to strengthen the brain's 8 Core Cognitive Capacities. REJUVENATE™ is an adult brain health program using the same cognitive exercise methodology to address geriatric depression and age-related cognitive decline. Both products include built-in cognitive assessments, real-time data reporting, and adaptive difficulty adjustment based on user performance.

Differentiator

Problem solved

Functional benefit

Brands

• ACTIVATE: Cognitive training software and physical exercise program for children designed to improve cognitive function, focus, self-control, and memory. Clinically proven to reduce effects of ADHD and improve learning outcomes.
• REJUVENATE

Products and services

• ACTIVATE™ A cognitive cross-training program for children that combines neuroscience-based adaptive computer games and structured physical exercises to strengthen the brain's 8 Core Cognitive Capacities. Targets children with ADHD and learning difficulties, with documented improvements in focus, self-control, working memory, and academic outcomes; sold via home subscription and K-12 site licensing.
• REJUVENATE™ A brain health improvement program for older adults designed to reduce stress, anxiety, and depressed feelings and to improve cognitive function. Uses the same adaptive cognitive exercise methodology as ACTIVATE, with built-in cognitive assessments and real-time progress reporting; sold as a direct-to-consumer subscription.

Quantifiable outcome

• 53% of children with ADD/ADHD showed significant improvement in self-management abilities
• +5 more outcomes

Named customers2 records

Segments6 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Scale indicators9 records

Recent moves6 records

Expansion highlights5 records

Broad incumbents

• DreamBox Learning: DreamBox provides adaptive K-12 math instruction with real-time data dashboards, comparable to C8's adaptive cognitive engine and school-channel data reporting. While DreamBox is math-focused, its adaptive-personalization and school-licensing model mirrors ACTIVATE's K-12 enterprise approach.
• Lexia Learning (Cambium Learning): Lexia provides evidence-based literacy and reading intervention technology for K-12 schools, overlapping with C8's school-channel GTM and reading-outcome claims (e.g., 'one full grade level in 8 weeks'). As a much larger EdTech incumbent, Lexia competes for the same supplemental-instruction budget dollars.

Direct peers

• NeuroNation: NeuroNation offers brain-training exercises in a subscription DTC and enterprise format for cognitive performance, overlapping with REJUVENATE's adult cognitive enhancement use case. It is comparable in business model (subscription, B2C and B2B) and product modality (adaptive cognitive exercises) to C8.
• LearningRx: LearningRx delivers cognitive training programs both in-center and online for children and adults with ADHD, dyslexia, and other learning challenges — directly comparable to ACTIVATE's target segments. Both companies emphasize measurable cognitive outcomes over generic tutoring.
• CogniFit: CogniFit provides a cognitive assessment and personalized training platform for both children and adults, overlapping with C8's ACTIVATE and REJUVENATE across age segments. It also offers a school/institutional channel and a subscription DTC product similar to C8's tiered pricing model.
• Akili Interactive: Akili developed EndeavorRx, an FDA-cleared digital therapeutic for pediatric ADHD using cognitive-game mechanics — the closest direct competitor to ACTIVATE in the neuroscience-based, game-driven ADHD cognitive training category. Like C8, it targets attention/executive function through adaptive digital exercises, but Akili pursued FDA clearance and prescription channels.
• Scientific Learning (FastForWord): Scientific Learning's FastForWord is a neuroscience-based reading and cognitive intervention product for K-12 schools, directly comparable to ACTIVATE's school-channel positioning. Both target struggling learners, use brain-plasticity research foundations, and sell into school districts as supplemental intervention.
• Posit Science (BrainHQ): Posit Science offers BrainHQ, a cognitive training platform with clinically validated exercises for older adults and clinical populations, directly comparable to C8's REJUVENATE product. Both companies emphasize neuroscience research pedigree and published clinical evidence rather than generic 'brain games' marketing.
• Lumosity: Lumosity is the largest consumer brain-training subscription platform, overlapping directly with REJUVENATE's DTC adult cognitive-enhancement positioning. C8 differentiates through clinical/research depth, but Lumosity represents the consumer incumbent that has shaped buyer expectations and the regulatory environment for the category.

Emerging players

• Pear Therapeutics: Pear Therapeutics pioneered prescription digital therapeutics (PDTs) including cognitive targets, representing the FDA-cleared clinical channel that C8 has chosen not to pursue. Pear illustrates the higher-value, payer-reimbursed path that C8 has deliberately avoided — a strategic choice that defines its current positioning.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/C8Sciences
• Facebookfacebook.com/201979106516400
• LinkedInlinkedin.com/company/c8-sciences

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds1 record

Investors2 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about C8 Sciences