Pizeta Pharma S.p.A.

What Pizeta Pharma S.p.A. does

Pizeta Pharma S.p.A. is an Italian privately held pharmaceutical company (Società per Azioni) founded in 2010 and headquartered in Ponte San Giovanni (Perugia), Italy. The company develops and commercializes food supplements, CE-certified medical devices, and cosmetics across four defined therapeutic areas: women's health (gynecology, obstetrics, endocrinology with focus on PCOS, menopause, pregnancy), vascular and microcirculation, dermatology (skin barrier and atopic dermatitis), and ophthalmology. Its branded portfolio includes Endokirogen and Dikirogen Zero (PCOS/hyperandrogenism), Flavoxelle (menopause), Iside HPV and Iside Femme (vaginal medical devices), StaminFlux (chronic venous insufficiency), PizetaTopic and Pizetalen (skin barrier repair), Pi-Vit and Zeta-Mac (ocular health), and Sferafer (iron deficiency). The company employs between 11 and 50 people and operates ISO 9001-certified quality management, plus an Organization Model per Italian Legislative Decree 231/2001.

The company's technology approach combines its own patented Sferafer gastro-resistant, slow-release microencapsulation technology for iron with proprietary branded ingredients licensed from third-party innovators — including µsmin Plus (micronized diosmin with claimed 9x bioavailability), KSM-66 Ashwagandha, Quatrefolic folate, WellPEA, Moodreal saffron, BioCell Collagen, MAGSHAPE magnesium, and Bioecolians prebiotic. Several products are supported by clinical studies (e.g., Endokirogen PCOS study, µsmin Plus CVD study), which provide the scientific evidence underpinning specialist recommendations.

Commercially, Pizeta operates a hybrid go-to-market model. In Italy, it sells directly to consumers via its own e-commerce storefront and through medical specialist recommendations (gynecologists, endocrinologists, cardiologists, dermatologists, ophthalmologists). Internationally, products are distributed in more than 20 countries through partner networks where Pizeta provides scientific, regulatory, and marketing planning support. Revenue is generated through one-time product sales across food supplements, medical devices (CE 0425), and cosmetics. The company has raised only one disclosed external funding round — €539,700 from INGENIUM Umbria Fund in February 2011 — and appears to have funded subsequent growth primarily through operating cash flow.

Name

Pizeta Pharma S.p.A.

Legal name

PIZETA PHARMA S.p.A.

Website

https://pizetapharma.com

Company type

Private

Founded year

2010

Operating status

Operating

Headcount range

11–50 employees

Short description

Pizeta Pharma S.p.A. is an Italian pharmaceutical company founded in 2010 that develops and commercializes food supplements, CE-certified medical devices, and cosmetics across women's health, vascular, dermatology, and ophthalmology therapeutic areas, distributing in over 20 countries via specialist recommendations and partner networks.

Ownership category

akta.pro rank

Product category

Nutraceuticals and Pharmaceutical Consumer Health

NAICS

Medicinal and Botanical Manufacturing (325411), Pharmaceutical and Medicine Manufacturing (3254), Food (Health) Supplement Retailers (456191), Health and Personal Care Retailers (456)

SIC

Medicinal Chemicals & Botanical Products (2833)

akta.pro industry

PRIMARYCRADAGAK

Women’s Health Supplements (Prenatal, Menopause, Hormonal)

Consumer Products & Retail/Consumer Packaged Goods (CPG) Manufacturing & Brands/Vitamins, Supplements & Sports Nutrition

SECONDARYCRADAGAD

Herbal & Botanical Supplements

Consumer Products & Retail/Consumer Packaged Goods (CPG) Manufacturing & Brands/Vitamins, Supplements & Sports Nutrition

SECONDARYCRADAGAB

Vitamins & Minerals (Single Nutrients)

Consumer Products & Retail/Consumer Packaged Goods (CPG) Manufacturing & Brands/Vitamins, Supplements & Sports Nutrition

SECONDARYAFAJAKAK

Condition-Specific Bioactives (Glucosamine/Chondroitin, Plant Sterols, Melatonin, Lutein/Zeaxanthin)

Agriculture & Food Production/Food Ingredients & Additives/Nutraceutical & Functional Ingredients (Vitamins, Minerals, Omega-3s, Botanicals)

SECONDARYHLAIAAAJ

Endocrinology & Reproductive Health Pharmaceuticals (incl. Women’s Health)

Healthcare & Life Sciences/Pharmaceuticals/Branded (Innovator) Pharmaceuticals

SECONDARYEUAAAIAK

Bio-based Pharmaceuticals, Nutraceuticals & Specialty Bioactives

Energy, Utilities & Environment/Bioenergy, Natural Gas & Biomass/Biorefining & Bio-based Chemicals (Co-products, Bioproducts)

Keywords

• Nutraceutical formulations
• Pharmaceutical food supplements
• Medical device manufacturing
• Women's health therapeutics
• Dermatological cosmetic products

Headquarters

HQ city

Ponte San Giovanni

HQ country

Italy

HQ region

Europe

Offices3 records

Markets served

GTM type

B2C

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Personnel, Marketing or Sales, Technology or R&D, Others

Revenue model

1. Food Supplements: Sale of nutraceutical products for women's health, vascular support, ophthalmology, and dermatology applications. Includes products like Endokirogen, Flavoxelle, Endomox 600, StaminFlux, Iside 4R Plus, and others targeting specific therapeutic areas.
2. Medical Devices: CE 0425 certified medical devices for vaginal use including Iside HPV and Iside Femme for treatment of uro-vaginal bacterial and fungal infections.
3. Cosmetics: Cosmetic products including Pizetatopic cream for atopic dermatitis, Pizetalen anhydrous ointment, StaminFlux Fast gel cream, and AlivYo Plus intimate hygiene detergent.

Go-to-market motion1 record

Distribution channels3 records

Marketing channels5 records

Core offering

Pizeta Pharma S.p.A. develops, manufactures, and commercializes therapeutic food supplements, CE-certified medical devices, and dermatological/cosmetic products across four core therapeutic areas: gynaecology and obstetrics (PCOS/PMOS, menopause, pregnancy support, vaginal health), vascular and microcirculation (chronic venous insufficiency, leg heaviness), dermatology (atopic dermatitis, skin barrier repair), and ophthalmology (vitreous body, macular health). The company leverages patented delivery technologies and proprietary ingredient partnerships (e.g., Sferafer slow-release iron, µsmin Plus micronized diosmin, Quatrefolic folate, KSM-66 Ashwagandha) to differentiate its formulations from standard supplements.

Product overview

Pizeta Pharma S.p.A. is a pharmaceutical company founded in 2010 specializing in food supplements, medical devices, and cosmetics for human well-being. The product portfolio is organized into four therapeutic areas: Gynecological (covering obstetrics, endocrinology, PCOS/PMOS, menopause), Vascular (microcirculation, chronic venous insufficiency), Ophthalmological (vitreous body, macular health), and Dermatological (skin barrier, atopic dermatitis). Products include VIVADIE and ERITRIL PRO (recent 2026 launches), Dikirogen Zero for PCOS/PMOS, Endokirogen for hyperandrogenism, Flavoxelle for menopause, Iside probiotic line for vaginal health, StaminFlux for venous insufficiency, Endomox 600 for homocysteine control, Pizetalen and PizetaTopic for skin barrier repair, and medical devices like Iside HPV and Iside Femme. The company operates internationally with products present in more than 20 countries.

Differentiator

Problem solved

Functional benefit

Brands

• PizetaTopic: Cream with repairing action against atopic dermatitis and skin changes
• Naxend
• Pi-Vit
• Endomox 600
• Iside HPV
• Iside 4R PLUS
• Iside Femme
• Flavoxelle
• StaminFlux Fast
• Dosìl Act
• Endokirogen
• Pizetalen
• PROBENAT GZ
• RIGENUR
• Dikirogen Zero
• VIVADIE
• ERITRIL PRO
• Sferafer
• AlivYo Plus
• Zeta-Mac

Products and services

• VIVADIE Food supplement designed to manage pelvic pain and psycho-behavioral symptoms during the menstrual cycle, including Premenstrual Syndrome (PMS) and Dysmenorrhea. Contains WellPEA, Magnesium (MAGSHAPE), Saffron (Moodreal), Bromelain, Vitamin D3 and Vitamin B6.
• ERITRIL PRO Food supplement based on liposomal iron, Vitamin C, Vitamin D3, active form of folic acid (Quatrefolic), Vitamin B12 and Vitamin B6 for iron deficiency.
• Dikirogen Zero (Bustine) Food supplement sachet format based on Myo-inositol, D-chiro-inositol, Manganese, Folic acid and Vitamin D for women with PCOS/PMOS.
• Dikirogen Zero Compresse Food supplement tablet format based on Myo-inositol, D-chiro-inositol, Manganese, Folic acid and Vitamin D for women with PCOS/PMOS.
• RIGENUR Food supplement containing D-Mannose, Lactoferrin, Collagen peptides and Hyaluronic acid for urinary tract support.
• Iside Femme Medical device for vaginal use indicated in the treatment of uro-vaginal bacterial and fungal infections.
• PROBENAT GZ Food supplement designed for pregnancy with L-Arginine, L-Citrulline, Willow Extract, Magnesium (MAGSHAPE), Iodine, Vitamins C, D, B12 and Folate (QUATREFOLIC) to support maternal and fetal vascular system.
• Pizetalen Anhydrous ointment with emollient, soothing and restorative properties for skin and mucous membranes (genital and perianal). Contains rice bran oil, shea butter, sweet almond oil, beeswax, sunflower seed oil, cocoa butter, olive oil, vitamin E, and extracts of chamomile, calendula, mallow and St. John's wort.
• Endokirogen Food supplement designed for women with hyperandrogenism. Based on myo-inositol, D-chiro-inositol, folic acid and manganese. Clinically studied in PCOS patients.
• StaminFlux Fast Compresse Food supplement based on micronized Diosmin and flavonoids (µsmin Plus), Hesperidin, Bromelain from Ananas comosus, Proanthocyanidins from Vitis vinifera and Sweet Clover for chronic venous insufficiency and microcirculation.
• StaminFlux Fast Crema Gel Cosmetic gel cream for immediate relief and well-being of legs with natural active ingredients including diosmin, troxerutin, aescin, horse chestnut, rusco, arnica, sweet clover, eucalyptus and centella asiatica.
• Dosìl Act Food supplement based on Ginger extract, Inulin and Vitamins B1, B2, B6 for naturally countering pregnancy-related nausea.
• Flavoxelle Food supplement for menopausal symptoms without phytoestrogens. Contains lemon extract (Flavox), Ashwagandha (KSM-66) and Magnesium. Reduces hot flashes, insomnia, irritability, mood swings, fatigue and improves cognitive and sexual function.
• Iside 4R PLUS Food supplement based on 10 billion probiotics (Bifidobacterium animalis ssp. Lactis, L. Rhamnosus, L. Plantarum, L. Crispatus), prebiotics (Bioecolians), folic acid, vitamin D and vitamins B for intestinal and uro-vaginal microbiota balance.
• AlivYo Plus Detergent for daily intimate hygiene with emollient and decongestant action. Contains Deoplex, lactic acid, calendula and lichen extract, allantoin, oat proteins. Suitable for pregnancy, postpartum and vaginal infections.
• Endomox 600 Food supplement based on N-acetyl-L-cysteine, betaine, vitamin B6, vitamin B2, vitamin B12 and folic acid (Quatrefolic) for effective plasma homocysteine control.
• Iside HPV Medical device for vaginal use (14 ovules) indicated for HPV support. CE 0425 certified.
• PizetaTopic Repairing cream specifically formulated to restore the balance of the skin barrier. Contains black currant oil, urea, aloe juice, olive oil, ceramide 3 and cholesterol. Ideal for atopic dermatitis and other skin changes.
• Naxend Food supplement based on Alpha-Lipoic Acid controlled-release, N-Acetylcysteine and Bromelain for neurological and antioxidant support.
• Pi-Vit Food supplement contributing to the physiological maintenance of the vitreous body. Contains BioCell Collagen, glucosamine, magnesium, grape seeds from Vitis Vinifera, hyaluronic acid, vitamin E and vitamin B6.
• Sferafer Food supplement based on divalent iron (ferrous fumarate), copper and vitamin C microencapsulated in a patented gastro-resistant and slow-release formulation for iron deficiency anemia.
• Zeta-Mac Food supplement for vision well-being and protection of ocular neurosensory layers. Contains DHA, Selenium, Vitamin E, Lutein and Zeaxanthin from Tagetes Erecta L.

Quantifiable outcome

• μsmin Plus demonstrated 9x superior bioavailability compared to standard micronized diosmin in clinical study on healthy volunteers
• +2 more outcomes

Segments4 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature10 records

Scale indicators2 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Giellepi S.p.A. Italian nutraceutical ingredient company and brand owner of µsmin Plus and WellPEA — both used in Pizeta formulations. Operates in the same women's-health and vascular nutraceutical segments with similar Italian/European distribution.
• Uriach (Laboratorios Uriach): Spanish specialty nutraceutical and consumer-health company with strong women's-health, digestive, and OTC franchises. Comparable product mix and physician-channel distribution across Southern Europe.
• Aboca S.p.A. Italian natural-health company selling botanical-based supplements, medical devices, and cosmetics for women's health, gastrointestinal, and respiratory care. Closest domestic peer in product mix and Italian market positioning.
• Scharper S.p.A. Italian nutraceutical and consumer-health firm with focus on gynaecology, dermatology, and cardiovascular supplements. Overlaps with Pizeta's therapeutic-area portfolio and physician-channel distribution model.
• Named Sport / Named Group: Italian nutraceutical company specializing in food supplements and medical devices across women's health, dermatology, and metabolic conditions. Direct overlap with Pizeta's product portfolio and Italian distribution.
• ESI S.p.A. Italian nutraceutical and natural-cosmetic company with broad women's-health, vascular, and dermatology product lines and international distribution — comparable scope, size, and channel strategy.
• Italfarmacia / Italfarmaco Group: Italian specialty pharma and women's-health company with supplements, OTC and prescription lines across gynaecology, obstetrics, and dermatology. Closely comparable therapeutic focus, size class, and physician-channel go-to-market.

Broad incumbents

• Perrigo Company plc: Global leader in consumer self-care products including OTC and women's-health supplements. Operates broadly across multiple categories and geographies; not specialty-focused but directly competes for retailer shelf space and physician recommendations.
• Bayer Consumer Health: Global consumer-health division of Bayer with brands in women's health, cardiovascular, and dermatology (e.g., Elevit, Bepanthen). Competes for physician recommendation and pharmacy shelf space across the same therapeutic areas as Pizeta.
• Sanofi Consumer Healthcare: Global consumer-healthcare business with supplements, vitamins (e.g., Nature's Own), and women's-health offerings. Significant scale advantage and broader portfolio; competes for the same Italian pharmacy channel.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Pizeta Pharma S.p.A.