Giellepi

What Giellepi does

Giellepi S.p.A. is a privately held, family-owned (Terruzzi family) Italian B2B ingredient developer and supplier founded in 1998 in Milan. The company sells science-backed proprietary branded ingredients for the nutraceutical, dietary supplement, sports nutrition, and cosmeceutical markets, alongside exclusive Italian-market distribution of branded ingredients from international manufacturers. Its proprietary portfolio includes μsmin® Plus (diosmin-based vascular health ingredient with 9.4x bioavailability vs micronized diosmin), Kalita® (Citrus bergamia phytocomplex for cardiometabolic health, produced via patent-pending clean water extraction), Axtragyl® (Astragalus membranaceus extract for joint and muscle health), Wellpea® (water-dispersible PEA + Acmella oleracea), the Poolzyme® family of fungal fermentation enzyme blends, Bromeyal® (pineapple-stem proteolytic enzyme), Betteral® (food-grade alpha lipoic acid), and Weizy® (Heyndrickxia coagulans probiotic). The technology base combines proprietary extraction, purification, and controlled fermentation methods validated through 63+ peer-reviewed publications and approximately 3 clinical studies per year, with ~7% of revenue reinvested in R&D and ongoing collaborations with the University of Milan DeFENS department.

Giellepi operates a dual revenue model: (1) proprietary branded ingredient sales to nutraceutical, dietary supplement, sports nutrition, and cosmeceutical manufacturers and brand owners, and (2) distribution of international branded ingredients (e.g., from IFF, Morinaga, Gnosis by Lesaffre, Algatech, Natural Remedies, Arjuna, Milei, and others) into the Italian and select global markets under long-term commercial partnerships. Go-to-market is enterprise field sales-led, with presence at major international trade events (Vitafoods Europe, SupplySide West), technical-documentation-driven content marketing, and direct quotation-based pricing. Primary customers are third-party contract manufacturers and brand owners seeking differentiated, clinically supported ingredients for finished formulations; a secondary segment is Italian nutraceutical distributors handling international branded ingredients. The company is ISO 9001 certified (RINA) and operates from a registered office in Milan (Via A. Saffi, 21) and an operational office in Seregno (Via G. Verdi, 41/Q). A 2010 spin-off created Giellepi Pharmaceuticals Srl to house the legacy API distribution business, and a 2021 divestiture of the finished products division sharpened the firm's focus on high-value-added proprietary ingredients.

Name

Giellepi

Legal name

Giellepi S.p.A.

Website

https://giellepi.com

Company type

Private

Founded year

1998

Operating status

Operating

Headcount range

11–50 employees

Short description

Giellepi S.p.A. is a family-owned Italian B2B ingredient developer and supplier, founded in 1998, that produces science-backed proprietary branded nutraceutical ingredients (μsmin® Plus, Kalita®, Axtragyl®, Wellpea®, Poolzyme®, Bromeyal®, Betteral®, Weizy®) and distributes international branded ingredients to contract manufacturers and brand owners.

Ownership category

akta.pro rank

Product category

Nutraceutical Ingredients

NAICS

Drugs and Druggists' Sundries Merchant Wholesalers (424210)

SIC

Medicinal Chemicals & Botanical Products (2833)

akta.pro industry

PRIMARYCRADAGAD

Herbal & Botanical Supplements

Consumer Products & Retail/Consumer Packaged Goods (CPG) Manufacturing & Brands/Vitamins, Supplements & Sports Nutrition

SECONDARYCRADAOAO

Ingredient Blends & Systems / Custom Formulation (Seasoning Systems, Functional Blends)

Consumer Products & Retail/Consumer Packaged Goods (CPG) Manufacturing & Brands/CPG Ingredients, Flavorings & Additives Brands

SECONDARYAFAJAKAK

Condition-Specific Bioactives (Glucosamine/Chondroitin, Plant Sterols, Melatonin, Lutein/Zeaxanthin)

Agriculture & Food Production/Food Ingredients & Additives/Nutraceutical & Functional Ingredients (Vitamins, Minerals, Omega-3s, Botanicals)

Keywords

• Nutraceutical ingredients
• Dietary supplements
• Sports nutrition ingredients
• Cosmeceutical ingredients
• Branded ingredient supplier

Headquarters

HQ city

Seregno

HQ country

Italy

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Supply Chain, Operations, Personnel, Marketing or Sales

Revenue model

1. Proprietary Branded Ingredient Sales: Sale of proprietary nutraceutical branded ingredients developed and owned by Giellepi, including μsmin® Plus, Kalita®, Axtragyl®, Poolzyme®, Bromeyal®, Betteral®, Weizy®, and Wellpea®.
2. International Branded Ingredient Distribution: Distribution of industry-leading branded ingredients from innovative international manufacturers to the Italian and global nutraceutical markets through long-term commercial partnerships.
3. Premium Functional Ingredient Supply: Supply of selected premium functional ingredients with highest quality and purity standards to supplement manufacturers.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels5 records

Core offering

Giellepi develops, manufactures and supplies science-based proprietary branded nutraceutical ingredients—μsmin® Plus, Kalita®, Axtragyl®, Wellpea®/ROSSOPURO® Forte, Poolzyme® (MULTI/DAIRY/VEG/KETO), Bromeyal®, Betteral® and Weizy®—for nutraceutical, dietary supplement, sports nutrition and cosmeceutical manufacturers and brand owners. The company also distributes industry-leading branded ingredients from international partners (IFF, Morinaga, Gnosis, Algatech, etc.) into the Italian and global markets. All offerings are sold B2B on a quote basis with technical documentation, samples and clinical evidence provided to support customer formulation and marketing claims.

Product overview

Giellepi is a developer and supplier of science-based ingredient solutions for the nutraceutical, dietary supplement, sports nutrition, and cosmeceutical markets. The company offers a portfolio of proprietary branded ingredients (μsmin® Plus, Kalita®, Axtragyl®, Wellpea®, Poolzyme® line, Bromeyal®, Betteral®, Weizy®) alongside industry-leading brands from global manufacturers. Giellepi's proprietary ingredients are validated through scientific research including preclinical studies and clinical trials, with a focus on charactering phytochemicals, demonstrating bioactivity, and publishing results in international journals. The portfolio spans vascular health (μsmin® Plus), cardiometabolic health (Kalita®), joint/muscle health (Axtragyl®), pain management (Wellpea®), digestive health (Poolzyme® line, Bromeyal®, Weizy®), and nerve health (Betteral®).

Differentiator

Problem solved

Functional benefit

Brands

• μsmin® Plus: Breakthrough diosmin-based ingredient specifically validated to support tired and heavy legs
• Kalita®
• Axtragyl®
• Wellpea®
• Poolzyme®
• Bromeyal®
• Betteral®
• Weizy®

Products and services

• μsmin® Plus Breakthrough proprietary diosmin-based branded ingredient specifically validated to support tired and heavy legs, promote leg vein health and vascular circulation in aging and everyday conditions. Sold to nutraceutical and dietary supplement manufacturers and brand owners.
• μsmin® Plus SG Finer-particle-size formulation of the μsmin® Plus diosmin ingredient engineered for softgel and gummy dosage forms, offering enhanced bioavailability for innovative finished supplement formats. Intended for dietary supplement manufacturers.
• Kalita® Clinically researched natural phytocomplex derived from Citrus bergamia Risso grown along Southern Italy's coast for cardiometabolic health support. Sold as a proprietary branded ingredient to nutraceutical and supplement manufacturers.
• Axtragyl® Natural standardized extract from Astragalus membranaceus root designed to support everyday joint and muscle health, mobility and flexibility for dietary supplement manufacturers and brand owners. Validated for gut-friendly properties.
• Axtragyl® WD Water-dispersible stick-pack variant of the Axtragyl® Astragalus extract ingredient, providing enhanced formulation flexibility for supplement manufacturers.
• Wellpea® / ROSSOPURO® Forte Advanced water-dispersible ingredient combining Palmitoylethanolamide (PEA) with Acmella oleracea extract, designed to alleviate daily physical discomfort and support nerve/nervous system health in finished supplement formulations. Sold to nutraceutical manufacturers and brand owners.
• Poolzyme® MULTI Powerful digestive enzyme formula with five key fungal-origin enzymes (cellulase, amylase, protease, lactase, lipase) supporting digestion of proteins, carbohydrates, fats, lactose and fibers. Sold to digestive-health supplement manufacturers.
• Poolzyme® DAIRY Triple-action enzyme complex combining lactase, protease and lipase, designed for people with minor discomfort after consuming dairy products. Sold to digestive-health supplement manufacturers.
• Poolzyme® VEG Comprehensive blend of five fungal digestive enzymes tailored for plant-based diets, including alpha-galactosidase, cellulase, hemicellulase, pectinase and amylase. Sold to plant-nutrition supplement manufacturers and brand owners.
• Poolzyme® KETO High-strength fungal lipase and protease enzyme blend designed for low-carb and ketogenic diets to digest fats and proteins in finished supplement formulations.
• Bromeyal® Natural bromelain enzymatic complex isolated from pineapple stem that retains bioactivity after gastrointestinal transit without requiring enteric coating. Sold to anti-inflammatory and digestive supplement manufacturers, validated as part of the Gut-Friendly® portfolio.
• Betteral® Branded, food-grade (solvent-free) premium quality alpha lipoic acid ingredient supporting peripheral nerve health, with 14+ years of scientific research. Sold to nerve-health supplement manufacturers.
• Weizy® Resilient probiotic strain of Heyndrickxia coagulans (formerly Bacillus coagulans) featuring a thermostable spore coating, 94% GI transit survival and 36-month unrefrigerated shelf life. Sold to gut-health and sports-nutrition supplement manufacturers.
• International Branded Ingredient Distribution Long-term distribution of industry-leading branded nutraceutical ingredients sourced from leading international manufacturers into the Italian (and selected global) nutraceutical market, providing customers single-source access to globally innovative ingredients with local supply chain and regulatory support.

Segments3 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Six partnerships are on record, tiered minor and core.

• CK IngredientsminorGTM or Marketing Partner · 25 October 2023Joint marketing partnership for SupplySide West 2023 trade show, with CK Ingredients partnering to showcase μsmin® Plus SG ingredient solutions at booth #3618.
• IFF (International Flavors & Fragrances)coreTechnology or IntegrationLong-term commercial partnership for distribution of IFF's innovative ingredient portfolio in the Italian nutraceutical market.
• MorinagacoreTechnology or IntegrationPartnership for distribution of Morinaga's probiotic and ingredient solutions in the Italian market.
• Gnosis by LesaffrecoreTechnology or IntegrationCommercial partnership for distribution of Gnosis probiotic and ingredient products in Italy.
• Natural RemediescoreTechnology or IntegrationLong-term commercial partnership for distribution of Natural Remedies' botanical ingredient portfolio in Italian market.
• University of Milan - DeFENScoreStrategic or Co-development PartnerAcademic research partnership with the Department of Food, Environmental and Nutritional Sciences (DeFENS) for ongoing research on gut-friendly properties of botanical ingredients including Axtragyl®, Kalita®, and Bromeyal®.

Scale indicators6 records

Recent moves8 records

Expansion highlights5 records

Direct peers

• Sabinsa Corporation: US-based specialty ingredient company that develops, manufactures, and licenses clinically supported branded nutraceutical ingredients (e.g., BioPerine, Curcumin C3 Complex). Mirrors Giellepi's branded-ingredient strategy with proprietary science backed by published clinical studies.
• Gnosis by Lesaffre: Lesaffre business unit developing yeast- and fermentation-derived nutraceutical ingredients including probiotics and vitamins. Already a Giellepi partner, Gnosis directly competes in the enzyme/probiotic ingredient segment with comparable proprietary branded offerings.
• Indena S.p.A. Italian-headquartered developer and manufacturer of proprietary botanical extracts for the nutraceutical, dietary supplement, and cosmeceutical markets. Operates the same B2B branded-ingredient model with deep clinical documentation and a similar mix of proprietary science plus country partnerships, making it the closest comparable to Giellepi.
• Bio-Botanica: US-based botanical extract and nutraceutical ingredient manufacturer serving dietary supplement, food, beverage, and cosmeceutical brand owners. Closely comparable B2B specialty botanical ingredient model with similar customer profile and ingredient portfolio breadth.
• OmniActive Health Technologies: Specialty nutraceutical ingredient developer with proprietary branded products (e.g., Lutemax, Capsimax) backed by clinical research. Comparable size and B2B branded-ingredient model across vision, joint, metabolic, and metabolic health categories.

Broad incumbents

• Naturex (Givaudan): Major botanical extract and nutraceutical ingredient business now integrated into Givaudan's Taste & Wellbeing division. Operates a much broader portfolio across colors, antioxidants, and botanical extracts but competes in the same branded-ingredient space as Giellepi.
• IFF Health & Biosciences: Global ingredient giant with a substantial health and biosciences portfolio spanning probiotics, enzymes, and nutraceutical ingredients. Both a partner of Giellepi (for distribution in Italy) and a broader incumbent competitor serving multinational brand owners.
• Lonza Capsules & Health Ingredients: Major supplier of capsules and ingredient solutions to the global nutraceutical and dietary supplement industry. Competes broadly with Giellepi in serving brand owners and contract manufacturers, with much greater scale and CDMO capabilities.
• DSM Nutritional Products (dsm-firmenich): Leading global nutrition and health ingredient supplier with broad vitamins, nutraceutical, and functional ingredient offerings. Material incumbent competitor to Giellepi with significantly larger R&D and global commercial infrastructure.

Emerging players

• Morinaga Milk Industry Co., Ltd. Japanese dairy and functional ingredient company with proprietary probiotic strains (e.g., Bifidobacterium longum BB536) supplied globally. A Giellepi distribution partner and a comparable proprietary probiotic ingredient developer, though regionally concentrated in Asia.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks7 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/giellepi-spa

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Subsidiaries1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A1 record

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Giellepi