Clever Sys

Name

Clever Sys

Legal name

CleverSys, Inc.

Website

https://cleversysinc.com

Company type

Private

Founded year

2010

Operating status

Operating

Headcount range

1–10 employees

Ownership category

akta.pro rank

Product category

Pre-Clinical Animal Behavior Analysis Software

NAICS

Computer Systems Design and Related Services (5415), Custom Computer Programming Services (541511)

SIC

Services-Prepackaged Software (7372), Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Clinical Decision Support & Workflow Automation (Protocols, Templates, AI Scribing) (HLAMAGAH)

Keywords

• Animal behavior analysis
• Pre-clinical research software
• Video behavior recognition
• Neuroscience research tools
• Gait analysis systems

Headquarters

HQ city

Reston

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Software

Cost components

Technology or R&D, Personnel, Marketing or Sales, Operations, Supply Chain

Revenue model

1. Software Licenses: Sale of software licenses for automated behavior analysis including HomeCageScan, TopScan Suite, GaitScan, SocialScan, and over 26 other programs. Software provides automated tracking and behavior recognition for various animal models.
2. Hardware Systems: Sale and integration of specialized hardware including mazes (Barnes, T-Maze, Y-Maze, Water Maze), operant chambers, home cage environments, treadmills, and custom equipment designed for video analysis.
3. CRO Analytical Services: Contract research organization services providing video behavior scoring and analysis for cognitive tasks, circadian rhythm studies, social observation, and forced swim tests using company’s proprietary technology.
4. Customized Research: Behavioral research consultation services including research consultation, study design, video acquisition and analysis, and complex battery of tasks tailored to individual research needs.

Pricing tiers

Go-to-market motion1 record

Distribution channels2 records

Marketing channels7 records

Core offering

Clever Sys develops and sells video-based Behavior Recognition software (26+ specialized programs spanning locomotion, gait, social interaction, depression, cognition, seizure, ultrasonic vocalization, and zebrafish paradigms), complementary hardware apparatus (mazes, operant chambers, treadmills, home cage environments), and contract research/CRO services for pre-clinical animal behavior analysis. The flagship offering is patented Behavior Recognition technology that detects animal body parts from video and automatically classifies complex behaviors without artificial markers, validated to be more than 90% accurate versus human scoring.

Product overview

Clever Sys is a bioinformatics company specializing in automated animal behavior analysis through patented video-based Behavior Recognition technology. The product portfolio is organized as software, hardware, and research services. The software suite includes the PhenoScan Suite (with flagship HomeCageScan), TopScan Suite (general-purpose top-view analysis), NeurodegenScan Suite (gait/motor function), DepressionScan Suite (forced swim/tail suspension), and SocialScan Suite (social behavior). Over 26 specialized software programs cover behaviors from locomotion and gait to seizures, social interactions, ultrasonic vocalizations, and zebrafish analysis. Hardware products include mazes (Barnes, T, Y, Zero, E-P, Radial Arm, Water, Automated T), chambers (Operant, Empathy, Forced Swim, Social Behavior), gait apparatus (Treadmill, Runway, Free Walk Box, Parallel Rod), and home cage monitoring environments (Home Cage Env, Home Cage Rack, IVC-RackScan). CRO services offer behavioral research outsourcing including cognitive tasks, circadian rhythm analysis, social observation, and customized research design. The company also offers optogenetics/fiber photometry integration and RFID-assisted tracking capabilities.

Differentiator

Problem solved

Functional benefit

Brands

• PhenoScan Suite: Software suite for automated animal behavior analysis including HomeCageScan, TopScan Suite, and other specialized programs
• DepressionScan Suite
• SocialScan Suite
• NeurodegenScan Suite
• TopScan Suite
• HomeCageScan
• AnnoStar

Products and services

• Behavior Recognition Technology Clever Sys's patented next-generation video-based Behavior Recognition technology provides automated analysis of animal behaviors by detecting body parts (nose, forelimbs, body center, tail base) and classifying complex, naturalistic behaviors from video in real-time or offline, without artificial markers or animal coloring. Validated to be more than 90% accurate versus human scoring in locomotor activity analysis.
• HomeCageScan Flagship product in the PhenoScan Suite. Automatically studies unconstrained rodent behaviors in a home cage for extended periods (24/7), detecting behaviors when rodents are not manipulated by experimenters. Used in academic and pharma pre-clinical neuroscience research.
• TopScan Suite General-purpose top-view based behavior analysis system that was the first to use animal body parts (since 2002) for accurate behavior analysis. Applicable from basic animal tracking to complex tasks such as Novel Object Recognition.
• TopScan LITE Modified version of TopScan providing high quality at the lowest price in the market. Applications include Open Field, Novel Object Recognition, Maze Analysis, Morris Water Maze, Barnes Maze, and Place Preference.
• GaitScan Component of NeurodegenScan Suite for gait analysis of animals. Enables highly sensitive, non-invasive detection and evaluation of pathophysiological conditions in spinal cord injury, Parkinson's disease, Alzheimer's disease, ALS, arthritis, pain, and neuromuscular diseases.
• FreezeScan Automated freezing behavior detection for learning and memory studies in molecular biology, genetics, and cognitive science. Eliminates tedium, subjective bias, and inconsistency of manual observation.
• SeizureScan Specialized software for automated seizure behavior detection of rodents in a home cage. Analyzes side-view video and outputs seizure occurrences based on the Racine scale, in real-time or offline.
• TreadScan Component of NeurodegenScan Suite for gait analysis on a treadmill. Uses video of an animal walking on a transparent-belt treadmill with gait parameters analyzed from ventral-view footprints.
• KinemaScan Multi-dimensional analysis system combining ventral-view (TreadScan-based) and side-view joint-motion kinematic analysis from synchronized high-speed cameras up to 175 fps at 656x480. Provides comprehensive gait measures including stride time, stance/swing, paw pressure, print area, joint angles, and body rotation. Described as a complete GLP-compliant system under U.S. FDA 21CFR Part 58 spirit.
• AquaScan Highly versatile software for zebrafish (Danio rerio) behavior analysis in adults and larvae. Supports single/multiple organism tracking, TTL stimulus control, and paradigms including Open field, CPP, T-maze, Y-Maze, Fear Conditioning, Seizure, Locomotion, Photoaxis, Optokinetic, Shoaling, and Social Behavior.
• LadderScan Fully automated test for detecting motor performance, associative motor learning deficits, and cognitive phenotypes in mouse models. Uses touch-sensitive rungs on a horizontal ladder to measure step time, length, missteps, back steps, and jumps. Includes automated doors, tones, fans, shockers, and air puffs as cues.
• Frictionless TreadScan Fully automated test for detecting coordinated neuro-activities in head-fixed animals walking on a frictionless treadmill with a transparent belt. Enables simultaneous measurement of gait and neuro-function, and supports optogenetics, fiber photometry, and neuron firing studies during active walking.
• RFID-Assisted SocialScan Combines RFID tracking with video-based behavior recognition for high-accuracy animal ID over extended periods. Uses implanted RFID tags with an array of detectors under the cage to localize animals, combined with video analysis for reliable long-term multi-animal tracking in social behavior studies.
• SocialScan Quantitatively and qualitatively measures social behaviors of up to 4 animals in a single arena. Automatically determines approaching, avoiding, following, contact, and sniffing at head, mid-body, or genital areas, and includes Social Distance tracking, Active/Passive Contact, and Mount detection. Part of the SocialScan Suite.
• AggressionScan Quantitative and qualitative measurement of aggressive social behaviors of up to 2 animals in a single arena. Detects aggressive approaching, withdrawing, chasing, fighting, stare, immobile, and exploration events. Part of the SocialScan Suite.
• GroupHousedScan Automatically analyzes behaviors of each animal when more than one animal is in a home cage and animals are not engaged in social interactions. Enables long-term monitoring of group-housed animals in their natural environment.
• GroupScan Behavioral assay software for analyzing behavior of groups of animals rather than single animals, addressing limitations of single-animal assays in learning, memory, fear conditioning, anxiety, and depression experiments.
• Circling Module Independent module that automatically detects repetitive circling behaviors in animal models of neurodegenerative disease (Parkinson's, Alzheimer's). Works in large arenas (animal appears small) or small cylinders (animal appears large) and detects left/right/multi-directional circling with speed and radius constraints.
• LocoScan Automated analysis of locomotor activity in rodents. Outputs total distance traveled, average speed, turning angle, elongation, zone-specific statistics, and differentiates between InPlaceMovement and Locomotion. Supports high-throughput capability up to 32 arenas simultaneously with multiple cameras.
• RunwayScan Component of NeurodegenScan Suite for gait analysis using a runway apparatus. Enables non-invasive detection of gait parameters for spinal cord injury, Parkinson's, Alzheimer's, ALS, arthritis, and pain studies.
• FreeWalkScan Latest addition to NeurodegenScan Suite integrating gait analysis and bottom-view behavior analysis. Non-invasive detection for spinal cord injury, Parkinson's, Alzheimer's, ALS, arthritis, pain, neuromuscular, and skeletal muscle diseases.
• WatermazeScan Automates analysis of Morris Water Maze experiments. Detects all traditional measures (latency, swimming path length, mean velocity, quadrant time) plus novel parameters including turning ratio, proximity score, heading error, and turn-around detection.
• ForcedSwimScan Component of DepressionScan Suite. Automates the forced swim test (Porsolt et al.) for pharmacological assessment of antidepressant activity, providing more comprehensive data than manual observation.
• TailSuspScan Component of DepressionScan Suite. Automates the tail suspension test for assessing depressive-like behavior in rodents by detecting struggling and immobility actions.
• MazeScan Automates analysis of experiments on all maze types including Elevated Plus Maze, Zero Maze, Radial Arm Maze, Y-Maze, and T-Maze. Detects 4 distinct body parts (Nose, Forelimbs, Center, Tail base) for zone-based event detection, and includes Stretch-Attend, Protected SAP, Head-Dipping, and Supported Rearing detection.
• ObjectScan Novel Object Recognition (NOR) behavioral test of episodic memory for rodents. Automatically detects and records sniffing behavior on familiar and unfamiliar objects using reliable nose detection.
• FootFaultScan Formerly Parallel Rod apparatus and software. Measures foot faults via touch sensor, locomotor activity via top-view video, and partial foot faults via side camera. Used for vestibular/proprioceptive system assessment and ataxia measurement in research on gait, balance, multiple sclerosis, stroke, and drug intoxication.
• StereoScan Comprehensive dual-view (top and side) behavior analysis system integrating both views for overall information on activities and life patterns. Combines top-view locomotion accuracy with detailed side-view behaviors (eating, drinking, sleeping, grooming, rearing). Supports up to 2 arenas.
• TubeScan Software for scoring social dominance in laboratory rodents. Uses a narrow transparent tube where two animals meet from opposite ends; the one that forces the opponent to retreat is scored as more dominant. Complements RFID-Assisted SocialScan for social hierarchy analysis.
• IVC-RackScan First-of-its-kind IVC (Individually Ventilated Cage) Rack-based 24-hour home cage Behavior Recognition system. Turn-key solution for animal husbandry where animals are simultaneously required to be analyzed.
• SonoPhenoScan Specialized product for ultrasonic applications in lab animal phenotyping and social activity. Records and analyzes ultrasonic signals, detects spikes and chirps in pup communications. Works with various ultrasonic acquisition hardware (mini-3, U30 bat detectors; B&K, AviSoft, and DK microphone systems) and synchronizes with video-based behavior analysis.
• PrimateScan Software for automated detection of primate behaviors in transparent cages, similar to HomeCageScan. Behavioral measures are collected when test subjects are unconstrained, for more viable data in primate research.
• DrugEffectScan Optional module for TopScan detecting drug-induced behaviors including head waving and darting. Provides measures for head turn counts left and right.
• AnnoStar User-friendly, rapid manual behavior annotation software. Allows users to view video and manually annotate behaviors using keyboard key controls. Fully integrable with Clever Sys products allowing simultaneous automated and manual scoring. Works in real-time or offline with variable speed playback.
• PhenoScan Suite Software suite family including HomeCageScan as the flagship product for unconstrained behavioral phenotyping, plus multiple specialized detection modules for various behavioral paradigms.
• DepressionScan Suite Software suite including ForcedSwimScan, TailSuspScan, and Forced Swim Cabinet hardware for automated depression-related behavioral testing in rodents.
• NeurodegenScan Suite Gait and motor function analysis suite including GaitScan, TreadScan, RunwayScan, FreeWalkScan, and Runway hardware for neurodegenerative disease research.
• SocialScan Suite Social behavior analysis suite including SocialScan, AggressionScan, RFID-Assisted SocialScan, and SocialScan-related hardware for comprehensive social interaction studies.
• Optogenetics and Fiber Photometry Integration Integration capability allowing any Clever Sys software program to synchronize with optogenetic actuators, sensors, and fiber photometry devices using TTL signals and a specially developed software interface, enabling synchronized acquisition of behavioral and neural data.
• Barnes Maze Hardware apparatus for spatial learning and memory testing in rodents. Ideal for assessing drug effects or cognitive ability in CNS disorders such as Alzheimer's. Works with TopScan, MazeScan, or LocoScan. Available for rat or mouse.
• Operant Chambers CSI-CHM-FRM operant chamber systems for fear conditioning, self-administration, or any operant/classical conditioning behavioral paradigm. Includes shock floors for rats and mice and open-top design for self-administration.
• Forced Swim Cabinet CSI-FSW forced swim and tail suspension cabinet designed for depression-related behavioral testing. Color specifically chosen to maximize animal detection for video analysis, with separation walls for high-throughput screening.
• Water Maze CSI-MZ-WM Morris Water Maze for spatial learning and memory testing. Originally developed for rats, now widely used for hippocampal deficit assessment in transgenic and knock-out mice. Available for rats and mice.
• Empathy Chamber CSI-CHM-EMP Empathy (Social Learning) Test apparatus for assessment of social learning behavior and social fear conditioning in rodents, based on Chen et al., 2009.
• Social Behavior Environment CSI-SO-PP Social Behavior Environment with 3-compartment social preference apparatus and isolation cages for diverse social paradigm observation. Works with SocialScan software.
• Treadmill CSI-G-TRD treadmill for forced walking gait analysis of rats and mice, manufactured by Columbus Instruments, combined with specially designed light box and camera setup for TreadScan software.
• Runway CSI-G-RWY multi-modal lighting runway for free walking gait analysis. Features light through glass for viewing reflections of foot contact area and light from underneath via light panels for traditional foot modeling.
• Home Cage Environment CSI-EVN-HC customized environment with specialized white and IR lighting, camera enclosure, and TTL control for 24-hour home cage monitoring. Available in single or double stacked configurations for mouse and rat.
• Automated T-Maze (T-Li Maze) CSI-MZ-ATL rotating T-Maze for original discrimination learning and reversal learning via visual discrimination. Automates maze arms to eliminate experimenter interference.
• CRO Analytical Services Broad range of contract research organization services backed by Clever Sys's proven behavior analysis tools at industry best price with quick turnaround. Services include cognitive tasks (Morris Water Maze, Open field, Elevated Plus Maze, etc.), circadian rhythm, social observation tasks, and forced swim/tail suspension testing.
• Customized Research Behavioral research consultation leveraging Clever Sys's patented Behavior Recognition Technology and expert staff. Services include research consultation, video acquisition and analysis, study design, and complex task batteries across Neurotoxicology, CNS disorders, Social/Affective Disorders, Genetic Disorders, Pain, and Motor Disorders.

Quantifiable outcome

• LadderScan detected impaired motor learning in autism study when other approaches failed to show such sensitivity
• +2 more outcomes

Named customers5 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration7 records

AI capability3 records

Feature5 records

Partnerships

Two partnerships are on record, tiered core.

• Triangle BioSystems, Inc.coreStrategic or Co-development Partner · 5 October 2009Teaming agreement between Yiqing Liang, Ph.D. of Clever Sys and James Morizio, Ph.D. of Triangle BioSystems for collaborative product development and market partnership.
• Vanderbilt Medical CentercoreTechnology or IntegrationInstallation of Clever Sys behavioral recognition software at Vanderbilt Laboratory for Neurobehavior, a 9,000 sq ft facility for brain disease research including autism, ADHD, and Alzheimer’s.

Scale indicators4 records

Recent moves5 records

Expansion highlights5 records

Direct peers

• Maze Engineers: Maze Engineers designs and sells behavioral apparatus (mazes, open fields, elevated plus mazes) for neuroscience research. Direct peer in the hardware side of pre-clinical behavioral testing, overlapping with Clever Sys's maze and chamber product lines.
• TSE Systems: TSE Systems provides behavioral phenotyping hardware and software (PhenoMaster, IntelliCage) for pre-clinical neuroscience and metabolic research. Direct peer offering integrated hardware-plus-software solutions to the same academic and pharma pre-clinical research market.
• Noldus Information Technology: Direct competitor offering video tracking and automated behavior analysis software (EthoVision XT) for animal research across academia and pharma. Closest direct peer to Clever Sys in computer-vision-based behavioral phenotyping, serving the same neuroscience and pre-clinical research market with overlapping product suites.
• Columbus Instruments: Columbus Instruments manufactures behavioral and metabolic instrumentation including treadmills (ExerGait) referenced by Clever Sys's TreadScan. Direct peer in the pre-clinical instrumentation space serving overlapping neuroscience and drug discovery customers.
• ViewPoint Behavior Technology: ViewPoint offers video tracking systems (VideoTrack, ZebraLab) for rodents and zebrafish behavior analysis. Direct peer in automated behavioral phenotyping with similar academic and pharma customer base.
• Stoelting Co. (ANY-maze): Stoelting's ANY-maze is a leading video tracking system for animal behavior analysis used widely in academic and pharmaceutical research. Direct peer competing head-to-head on top-view behavior tracking with similar target customers and pricing tier structure.
• Biobserve GmbH: Biobserve offers automated video tracking and behavior analysis software (Viewer, Motior) for rodents and zebrafish in pre-clinical research. Direct peer with comparable computer-vision behavior analysis offerings, particularly strong in social and home-cage paradigms overlapping with Clever Sys's SocialScan and HomeCageScan suites.

Broad incumbents

• Harvard Apparatus: Harvard Apparatus is a long-established distributor and manufacturer of life-science research equipment including pumps, stereotaxic frames, and behavior apparatus. Broad incumbent serving the same academic and pharma pre-clinical market with a much broader catalog than Clever Sys's focused behavior-analysis offering.
• Med Associates Inc. Med Associates provides a broad portfolio of behavioral research instruments (operant chambers, startle systems, activity monitors). Broader incumbent in pre-clinical behavioral instrumentation with overlapping customer base but a wider portfolio beyond automated video analysis.
• Danaher Corporation (Life Sciences segment): Danaher operates Beckman Coulter, Molecular Devices, and other life-sciences instrumentation brands used in pharma research. Broad incumbent with overlapping end customers in pre-clinical drug discovery; significant R&D and distribution scale relative to Clever Sys's niche focus.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

• Xx.com/cleversysinc
• Facebookfacebook.com/behaviorscientist
• LinkedInlinkedin.com/groups?home=&gid=4619690&trk=anet_ug_hm

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Clever Sys