All of Us Research

What All of Us Research does

The All of Us Research Program is a national research initiative of the U.S. National Institutes of Health (NIH), within the U.S. Department of Health and Human Services, aimed at building a longitudinal health dataset from more than one million participants across the United States to advance precision medicine. Volunteers enroll through a self-service online portal (participant.joinallofus.org) or in-person at partner healthcare facilities operated by a national consortium of academic medical centers and community health providers, including Banner Health, Mass General Brigham, UC Irvine, Yale University, Loma Linda University Health, MemorialCare, and VCU, among others. Participants contribute survey data on health and lifestyle, electronic health record data, and biological samples (blood, urine, saliva) housed in a central biobank, and can opt to receive DNA results and access their own health information at no cost.

The platform's core technology is a secure participant data collection system with a participant portal, electronic health record integration, a national biobank for biological samples, and Certificates of Confidentiality issued by the U.S. government to protect against compelled legal disclosure. Direct identifiers are removed and replaced with codes; a master code-to-name list is stored separately and securely. Longitudinal survey design allows the same questions to be re-asked over time, enabling researchers to study health trajectories rather than single snapshots. De-identified data is made available to approved researchers through a separate platform at ResearchAllofUs.org.

All of Us does not generate commercial revenue. It is funded through federal research appropriations to NIH, and participation is free for volunteers with no insurance required. Go-to-market is hybrid: direct-to-consumer recruitment via the website and participant portal, plus community-led enrollment through regional Enrollment and Engagement Partners (academic medical centers, community health centers, and healthcare provider organizations). Special enrollment pathways exist for Veterans (in coordination with the U.S. Department of Veterans Affairs) and for American Indians and Alaska Natives, with tribal consultation requirements and additional privacy protections. The 'All of Us' name and logo are registered service marks of the U.S. Department of Health and Human Services.

Name

All of Us Research

Legal name

All of Us Research Program

Website

https://joinallofus.org

Company type

Private

Operating status

Operating

Headcount range

1–10 employees

Short description

The All of Us Research Program is an NIH-funded national initiative that collects longitudinal health, electronic health record, and biospecimen data from one million-plus U.S. participants to enable precision medicine research, enrolling volunteers free of charge through academic medical center and community health partners.

Ownership category

akta.pro rank

Product category

Government Health Research Program

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714), Scientific Research and Development Services (5417), Medical Laboratories (621511)

SIC

In Vitro & In Vivo Diagnostic Substances (2835), Services-Commercial Physical & Biological Research (8731), Services-Medical Laboratories (8071)

akta.pro primary industry

Health Research Funding Agencies (Public/Quasi-Public) (HLAJALAB)

Keywords

• Precision medicine research
• Longitudinal health data
• Genomics research program
• Participant biobanking
• Federally funded cohort study

Headquarters

HQ city

Little Rock

HQ country

United States

HQ region

North America

Offices20 records

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales

Revenue model

1. Government Research Funding: As a National Institutes of Health (NIH) program, All of Us is funded through federal research appropriations rather than commercial revenue. The program does not charge participants to join.

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels5 records

Core offering

The All of Us Research Program is a U.S. National Institutes of Health (NIH) initiative that recruits more than one million volunteer participants across the United States to share health, lifestyle, and biological data (including blood, urine, and saliva samples) for longitudinal research. Participants enroll free of charge through an online portal or at partner healthcare facilities and may receive their own DNA results, while approved researchers access de-identified datasets through ResearchAllofUs.org to advance precision medicine.

Product overview

The All of Us Research Program is a large-scale health research initiative by the National Institutes of Health (NIH) that collects health data from participants to advance precision medicine. The program offers a participant enrollment portal where volunteers can sign up, share health information, habits, and lifestyle data, and optionally receive DNA/genomics results. Research data is made available to approved researchers through ResearchAllofUs.org. The program partners with healthcare provider organizations and enrollment centers across the United States to facilitate participant recruitment and data collection.

Differentiator

Problem solved

Functional benefit

Products and services

• Participant Enrollment Portal Free online self-registration portal where individual volunteers across the U.S. sign up to share health data, lifestyle habits, and location data with the program, optionally provide biological samples at partner sites, and access their own health information and DNA results.
• Researcher Data Access Platform (ResearchAllofUs.org) Controlled-access research platform that provides approved investigators with de-identified longitudinal health, survey, electronic health record, and genomic data collected from enrolled participants to support precision medicine studies.
• Biobank and DNA Results Service Storage and processing of biological samples (blood, urine, saliva) collected from participants, with return of individual DNA results to participants who opt in to receive them.

Quantifiable outcome

• More than one million people expected to join

Segments4 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

20 partnerships are on record, tiered core, flagship and regional.

• University of ArizonacoreStrategic or Co-development PartnerUniversity of Arizona is a member of the All of Us University of Arizona-Banner Health consortium, calling on Arizona volunteers to help speed up health research. Works with NIH and the All of Us Research Program to collect health data from participants.
• Banner HealthcoreStrategic or Co-development PartnerBanner Health operates multiple enrollment locations in Arizona and Colorado as part of the University of Arizona-Banner Health consortium. Provides facilities for participant health measurements and sample collection.
• Mass General BrighamcoreStrategic or Co-development PartnerAll of Us New England is based at Massachusetts General Hospital (part of Mass General Brigham). Mass General Brigham has been a trusted part of the greater Boston medical community for more than 200 years.
• University of California Irvine (UCI)coreStrategic or Co-development PartnerUCI is a member of the All of Us Southern California Consortium. UCI Health provides enrollment locations for the program in Orange County, California.
• Loma Linda University Health (LLUH)coreStrategic or Co-development PartnerLoma Linda University Health is a member of the All of Us Southern California Consortium working with the NIH to help speed up health research.
• MemorialCarecoreStrategic or Co-development PartnerMemorialCare is a member of the All of Us Southern California Consortium working to accelerate health research in Southern California.
• Yale UniversitycoreStrategic or Co-development PartnerYale University collaborates with All of Us California and PRCCI to enroll participants in Connecticut. Yale Center for Clinical Investigation (YCCI) manages enrollment operations.
• National Institutes of Health (NIH)flagshipOthersThe All of Us Research Program is a national research initiative funded and overseen by the National Institutes of Health (NIH). NIH provides the primary funding and programmatic direction for the program.
• Trans-American Consortium for HealthregionalStrategic or Co-development PartnerRegional enrollment and engagement partner for the All of Us Research Program.
• Cherokee Health SystemsregionalStrategic or Co-development PartnerRegional enrollment and engagement partner providing healthcare services and participant enrollment for the program.
• Community Health Center, Inc.regionalStrategic or Co-development PartnerRegional enrollment and engagement partner providing community health services and participant enrollment.
• Cooperative HealthregionalStrategic or Co-development PartnerRegional enrollment and engagement partner for the All of Us Research Program.
• All of Us Puerto RicoregionalStrategic or Co-development PartnerRegional enrollment center serving Puerto Rico, operating through PRCCI and University of Puerto Rico Comprehensive Cancer Center.
• All of Us WisconsinregionalStrategic or Co-development PartnerRegional enrollment and engagement partner serving Wisconsin.
• Illinois Precision Medicine ConsortiumregionalStrategic or Co-development PartnerRegional enrollment and engagement partner serving Illinois.
• All of Us HeartlandregionalStrategic or Co-development PartnerRegional enrollment and engagement partner serving the Heartland region.
• All of Us SouthEast Enrollment CenterregionalStrategic or Co-development PartnerRegional enrollment and engagement partner serving the southeastern United States.
• The University of Texas at TylerregionalStrategic or Co-development PartnerRegional enrollment and engagement partner serving Texas.
• VA (Department of Veterans Affairs)regionalStrategic or Co-development PartnerSpecial enrollment pathway for veterans, with dedicated participant portal registration and login options.
• VCU Wright Center for Clinical and Translational ResearchregionalStrategic or Co-development PartnerRegional enrollment and engagement partner serving Virginia.

Scale indicators2 records

Recent moves6 records

Expansion highlights5 records

Emerging players

• 23andMe: Consumer genomics company with a research database built from consented customers that it has monetized through pharma partnerships. Comparable in combining direct-to-consumer genetic data with research use, but operating commercially.
• Human Longevity Inc. Health intelligence company building a large database of genomic and clinical data for preventive and personalized medicine. Comparable in mission to enable precision medicine through integrated genomic and clinical datasets.

Direct peers

• deCODE Genetics (Amgen): Iceland-based human genetics company conducting large-scale population genomic studies linked to health records. Highly comparable in leveraging national-scale genetic and health data for research, though operated commercially under Amgen.
• UK Biobank: Large-scale prospective cohort study of ~500,000 UK participants with deep genomic, lifestyle, and health record data made available to researchers. Most direct peer in mission, scale, and operating model.
• Our Future Health: UK-based research program aiming to recruit 5 million participants and link genetic and health data for disease prevention research. Closely comparable in mission and large-cohort genomics design.

Regional players

• FinnGen: Public-private Finnish research project combining genome data with digital health records from a national biobank program. Comparable cohort-genomics design though focused on Finland.

Broad incumbents

• National Cancer Institute (NCI) Cohort Programs: Federally funded cancer-focused cohort studies (e.g., CONNECT, PLCO) that prospectively collect biospecimens and health data from large populations. Comparable as publicly funded, longitudinal health research cohorts under NIH, though disease-specific rather than population-wide.
• Mayo Clinic Biobank: Large institutional biobank at Mayo Clinic linking biological samples with electronic health record data for research. Comparable as a clinical-grade biobank supporting precision medicine research, though smaller in scale and academic in focus.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks4 records

Key highlights7 records

Customer concentration

• Xtwitter.com/AllofUsResearch
• YouTubeyoutube.com/channel/UCQId1TfpwPaYiDIGlxEhlkA/feed
• Facebookfacebook.com/AllofUsResearch
• Instagraminstagram.com/allofusresearch
• LinkedInlinkedin.com/company/allofusseec

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

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M&A

Investments

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Frequently asked questions about All of Us Research