Krishgen BioSystems
Krishgen BioSystems is an India-based ISO 13485 manufacturer of ELISA immunoassay kits for the global life sciences industry, serving pharmaceutical, biotech, CRO, clinical, and research customers in 100+ countries with proprietary biotherapeutic and bioprocess contamination assays.
- Company typePrivate
- Founded2003
- HeadquartersMumbai, India
- Headcount101–250
- GTM typeB2B
- OfferingHardware or Manufacturing
What Krishgen BioSystems does
Krishgen BioSystems is a Mumbai-headquartered manufacturer of ELISA-based immunoassay kits serving the global life sciences industry. Founded in 2003 by Kalpesh and Neelam Jain, the company transitioned from a proprietorship to Krishgen Biosystems Private Limited in July 2024 and operates a 10,000+ square foot ISO 13485 certified manufacturing facility in Bhiwandi, India, with US offices in Cerritos, CA and Lewes, DE. The product portfolio is organized around three core sub-brands — GENLISA (research-grade ELISA), KRIBIOLISA (premium bioprocess and biotherapeutic ELISA), and KRISHZYME (chromogenic coagulation enzyme assays) — spanning therapeutic drug monitoring, immunogenicity (anti-drug antibody) testing, host cell protein/DNA contamination, ADC/bispecific/fusion/peptide/transmembrane protein quantification, cytokine biomarkers, food safety, and recombinant enzymes.
The company's technology is built on classical enzyme-linked immunosorbent assay chemistry but is differentiated by proprietary formats: TELESCOPIC HCP ELISA using double-antibody coverage, anti-idiotypic monoclonal antibody dual-capture formats for bispecific antibody drugs, and J2-based dsRNA detection. Krishgen holds the world's first bispecific antibody drug ELISA range (40+ assays), the world's largest mAb-based TDM ELISA range (350+ targets), 25+ ADC ELISA kits, and a complete coagulation enzyme assay lineup. Validations follow US FDA/EMA ICH M10 bioassay guidelines with NIBSC/WHO calibration where available, and the facility carries CE IVD, ISO 9001, FDA India License, JAS-ANZ, AEO, and LTU certifications.
Krishgen generates revenue primarily through one-time sales of ELISA kits priced between approximately $310 and $5,770 per unit, distributed through a hybrid model of direct e-commerce (krishgen.com), regional distributors in Italy, Japan, Iberia, the USA, and Venezuela, marketplace channels (Labscoop, Fisher Scientific, SelectScience, Scientist.com), and an India-specific distribution site (krishgenbio.com). The company also offers custom assay development services and an Indian distribution franchise for international life sciences brands. Customers span pharmaceutical/biopharmaceutical firms, CROs, biologics manufacturers, clinical companies, food safety labs, academia, cosmetics, agriculture, and medical diagnostics firms in 100+ countries.
Krishgen BioSystems firmographics
Firmographics- Name
- Krishgen BioSystems
- Legal name
- Krishgen Biosystems Private Limited
- Website
- https://krishgen.com
- Company type
- Private
- Founded year
- 2003
- Operating status
- Operating
- Headcount range
- 101–250 employees
- Short description
- Krishgen BioSystems is an India-based ISO 13485 manufacturer of ELISA immunoassay kits for the global life sciences industry, serving pharmaceutical, biotech, CRO, clinical, and research customers in 100+ countries with proprietary biotherapeutic and bioprocess contamination assays.
- Ownership category
- akta.pro rank
Krishgen BioSystems industry classification
Industry- Product category
- ELISA Immunoassay Kits
- NAICS
- In-Vitro Diagnostic Substance Manufacturing (325413), Research and Development in Biotechnology (except Nanobiotechnology) (541714)
- SIC
- In Vitro & In Vivo Diagnostic Substances (2835)
- akta.pro primary industry
- Reagents, Chemicals & Assay Kits (Buffers, Antibodies, ELISA, Enzymes) (HLAGAIAI)
- akta.pro secondary industries
- Antibody Discovery & Engineering Platforms (display tech, bispecifics, Fc engineering) (HLAAAIAB), Therapeutic Peptides & Protein/Peptide Biologics (HLAAAAAH), Biomarker Assay & Reagent Development (LDT/IVD assay design, antibodies/standards/controls) (HLAAAMAL), Specialty & Biomarker Laboratory Services (Immunoassays/Flow/Cytometry) (HLAGAEAB), Cell-Based & Potency Assays (Bioassays) (HLAGADAH)
Keywords
Where Krishgen BioSystems is headquartered
LocationHeadquarters
- HQ city
- Mumbai
- HQ country
- India
- HQ region
- Asia
Offices3 records
Markets served
Krishgen BioSystems business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Personnel, Supply Chain, Operations, Technology or R&D, Infrastructure, Marketing or Sales
Revenue model
- ELISA Kit Sales: Sale of manufactured ELISA kits including GENLISA, KRIBIOLISA, and specialized product lines. Products sold directly through website and through distribution partners globally. Pricing ranges from approximately $310 to over $5,000 per kit depending on product type and complexity.
- Custom Assay Development Services: Custom ELISA assay development services for specific therapeutic targets not commercially available. Krishgen offers collaborative workflow with 20+ years expertise and fast turnaround time.
- Distribution of International Products: Distribution of life sciences reagents and tools from leading US and European companies for Indian market through distribution agreements. Started in 2004.
- Molecular Biology Reagents: Sale of molecular biology reagents including PCR kits, electrophoresis reagents, nucleic acid extraction kits, and enzymes.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Unit Pricing | Pay-as-you-go | Standard ELISA Kits - GENLISA Product Line |
| Unit Pricing | Pay-as-you-go | Premium ELISA Kits - KRIBIOLISA Product Line |
| Unit Pricing | Pay-as-you-go | Host Cell Protein ELISA Kits |
| Unit Pricing | Pay-as-you-go | Anti-Drug Antibody (Immunogenicity) ELISA |
| Unit Pricing | Pay-as-you-go | Specialty Assays - Coagulation Enzyme Kits |
| Unit Pricing | Pay-as-you-go | Viral/COVID-19 ELISA |
Go-to-market motion4 records
Distribution channels6 records
Marketing channels8 records
Krishgen BioSystems product offering
Product offeringCore offering
Krishgen BioSystems manufactures ELISA-based immunoassays, biochemical detection tools, molecular biology reagents, and recombinant enzymes for life-science research, biologics development, and bioprocess quality control. It also distributes third-party life-science products in India and provides custom assay development services for specialized therapeutic targets and sample types.
Product overview
Krishgen BioSystems is a manufacturer of ELISA-based immunoassays and biochemical detection tools for the life sciences industry. The product portfolio is organized around three core sub-brands: GENLISA (standard research-grade ELISA kits), KRIBIOLISA (premium bioprocess-grade assays with enhanced validation), and KRISHZYME (chromogenic coagulation enzyme assays). The offering spans therapeutic drug monitoring and pharmacokinetics (TDM/mAb ELISA, ADC ELISA, Bispecific Antibody Drug ELISA, Fusion Protein ELISA, Peptide Drug ELISA), immunogenicity testing (Anti-Drug Antibody/ADA ELISA, Neutralizing Antibody ELISA), biosafety and process contamination testing (Host Cell Protein HCP ELISA, Host Cell DNA ELISA, dsRNA ELISA, Antibiotic Residue ELISA), biomarker quantification (Human/Animal ELISA, Multiplex ELISA, Cytokine ELISA), specialty coagulation enzyme assays (Heparin Factor Xa/IIa assays), and molecular biology products (recombinant enzymes, PCR reagents). The company also provides custom assay development services. Products are manufactured in ISO 13485 certified facilities and validated according to FDA/EMA ICH M10 bioassay guidelines.
Differentiator
Problem solved
Functional benefit
Brands
- GENLISA: ELISA product brand line including GENLISA Gold Ring Cytokine ELISA range
- KRIBIOLISA
- KRISHZYME
- KRISHPLEX
- DHARMAPLEX
- GENBULK
- PrecisionBind
- TITANIUM
- FastNuclease
Products and services
- GENLISA Research-use ELISA kits covering cytokines, biomarkers, and general immunoassays across species including human, rat, mouse, and animal models.
- KRIBIOLISA Premium-grade ELISA kits with enhanced validation for biotherapeutics research, including pharmacokinetic and immunogenicity assays.
- KRISHZYME Chromogenic assays including Factor IIa and Factor Xa assays for heparin potency testing, validated as per IP, EP, and USP monographs.
- KRIBIOLISA Anti-Drug Antibody (ADA) ELISA Quantitative ELISA for detecting anti-drug antibodies in clinical and preclinical studies, with 30+ available targets.
- KRIBIOLISA Bispecific Antibody Drug ELISA ELISA range for quantifying bispecific antibody drugs, including BiTE and DART formats, in serum and plasma for pharmacokinetic analysis and therapeutic drug monitoring.
- KRIBIOLISA Antibody Drug Conjugate (ADC) ELISA ELISA kits for detecting and quantifying antibody-drug conjugates in biological matrices for pharmacokinetic analysis of ADC-based therapies.
- KRIBIOLISA Therapeutic Drug Monitoring (TDM) ELISA Pharmacokinetic ELISA kits for quantifying serum and plasma protein-drug levels across 350+ mAb targets for biosimilar and biologics research.
- KRIBIOLISA Host Cell Protein (HCP) ELISA TELESCOPIC HCP ELISA using two capture antibodies for broader detection of host cell proteins from CHO, E. coli, Vero, and HEK expression systems.
- Wide Coverage CHO HCP ELISA ELISA for comprehensive detection of host cell proteins across diverse CHO expression systems.
- KRIBIOLISA High Five (H5) HCP ELISA Direct sandwich assay for quantitatively measuring host cell proteins in products manufactured using High Five cell expression systems.
- KRIBIOLISA Host Cell DNA ELISA Sensitive ELISA for detecting and quantifying host cell DNA contaminants from CHO, E. coli, and insect-cell expression systems.
- KRIBIOLISA dsRNA (J2-based) ELISA Pre-coated ELISA for qualitative and semi-quantitative screening of double-stranded RNA in mRNA preparations, with a stated limit of detection of 1.5 ng/ml.
- KRIBIOLISA Bioprocess Antibiotic Residue ELISA ELISA kits for detecting process-related antibiotic impurities including colistin, erythromycin, neomycin, and tylosin in bioprocess workflows.
- KRIBIOLISA Fusion Protein ELISA ELISA kits for quantifying Fc-fusion therapeutics and other therapeutic fusion proteins in serum and plasma.
- KRIBIOLISA Peptide Drug ELISA ELISA range for quantitative estimation of peptide therapeutics, including GLP-1 agonists and insulin analogs.
- KRIBIOLISA Transmembrane Protein ELISA ELISA kits for measuring transmembrane proteins including Claudin 18.1, Claudin 18.2, Claudin 6, and GPCR5D using humanized capture antibodies.
- KRIBIOLISA Neutralizing Antibody ELISA ELISA for qualitative detection of neutralizing antibodies to monoclonal drugs that bind and neutralize therapeutic effects.
- GENLISA Viral Antigen and Antibody ELISA ELISA kits for viral antigen and host-antibody detection in diagnostic and vaccine research, including SARS-CoV-2, Dengue, Zika, Chikungunya, Hepatitis, and Influenza.
- Food Safety ELISA and Rapid Tests ELISA and rapid tests for food-safety analysis covering mycotoxins, allergens, bacteria, hormones, drug residues, and species identification.
- PrecisionBind Cytokine ELISA Kits High-performance cytokine assays for quantitative cytokine analysis in therapeutic antibody and cell-and-gene-therapy research.
- Biochemical Assays Validated biochemical assays for detecting analytes in metabolic pathways and for cell-viability studies.
- Recombinant Enzymes Recombinant enzymes spanning mRNA enzymes, glycobiology enzymes, and protein-modifying enzymes for research applications.
- Molecular Biology Products DNA and RNA ladders, PCR reagents, electrophoresis reagents, and extraction kits for molecular-biology research.
- Multiplex ELISA Multiplex immunoassays for simultaneous detection of multiple analytes, including pre-built and customized panels.
- International Life-Science Product Distribution Distribution in India of life-sciences reagents and tools from leading US and European companies.
- Custom Assay Development Services Collaborative custom ELISA development for specific therapeutic targets, animal samples, and specialized assay requirements.
Quantifiable outcome
- Lot-to-lot consistency with intra- and inter-assay precision <15%, typically <10% CV
- +4 more outcomes
Companies that use Krishgen BioSystems
Customer profileNamed customers8 records
Segments6 records
Ideal customer profiles5 records
Krishgen BioSystems technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature8 records
Krishgen BioSystems partnerships and signals
Strategic signalPartnerships
Eight partnerships are on record, tiered core, regional and minor.
- WHO/NIBSCcoreKrishgen participates in WHO and National Institute for Biological Standards and Control (NIBSC) collaborative study focused on standardization of anti-Adalimumab antibodies. Krishgen ELISA contributed to standardization efforts.
- DBA ItaliaregionalDistribution partnership for Italy. DBA Italia serves as regional distributor for Krishgen ELISA products in Italy, expanding Krishgen's European market presence.
- Alfa Quantum LabsregionalDistribution partnership for Venezuela. Alfa Quantum Labs distributes Krishgen ELISA products in the Venezuelan market.
- Labscoop.comminorMarketplace listing partnership. All ELISA manufactured by Krishgen are available for purchase through Labscoop.com online marketplace.
- Denis Pharma KKregionalDistribution partnership for Japan. Denis Pharma handles distribution of Krishgen ELISA products in Japan, supporting Krishgen's expansion in the Japanese market.
- Labclinics SAregionalDistribution partnership for Spain and Portugal. Labclinics SA serves as distributor for Krishgen ELISA products in the Iberian Peninsula.
- American Research Products (ARP)regionalDistribution partnership for USA. American Research Products is Krishgen's second US distribution partnership, complementing existing US sales operations.
- National Biomedical Resources Indigenization Consortium (NBRIC)coreKrishgen invited by Indian Government to join NBRIC as part of Make-In-India initiative for indigenization of biomedical resources. Krishgen develops assays for COVID-19 research as consortium member.
Scale indicators14 records
Recent moves6 records
Expansion highlights6 records
Krishgen BioSystems competitors and assessment
Company assessmentDirect peers
- Cayman Chemical: Cayman Chemical is a US-based manufacturer of ELISAs, antibodies, and biochemical reagents for inflammation, immunology, and metabolism research. Directly comparable on research-grade ELISA kits for cytokines, biomarkers, and specialty assays, with overlap to Krishgen's GENLISA portfolio for academic and pharma customers.
- RayBiotech: RayBiotech specializes in antibody arrays and ELISA kits for biomarker discovery and validation across cytokines, growth factors, and disease biomarkers. Directly comparable on biomarker ELISA offerings and overlap on multiplex/array formats that complement single-plex ELISA similar to Krishgen's catalog.
- Abcam (Danaher): Abcam, acquired by Danaher in 2023, is a global leader in antibodies and ELISA kits serving academic and biopharma researchers with a catalog of >20,000 targets including cytokine, biomarker, and biotherapeutic ELISA kits. Directly competes with Krishgen in research-grade and validation-grade ELISA kits across virtually the same customer segments.
- Bio-Techne: Bio-Techne (NASDAQ: TECH), through its R&D Systems brand, is one of the world's largest manufacturers of ELISA kits, antibody arrays, and Luminex multiplex assays for cytokines, biomarkers, and biotherapeutic drug development. Directly comparable on catalog breadth, validation standards, and biopharma customer base to Krishgen's GENLISA/KRIBIOLISA lines.
- Boster Bio: Boster Bio is a US-based manufacturer of ELISA kits and antibodies focused on cytokines, immunology, and neuroscience research, with direct-to-customer web sales in academia and biotech. Directly competes with Krishgen's GENLISA line on research-grade ELISA kits with comparable pricing and similar Asia-manufactured value proposition.
- Enzo Life Sciences: Enzo Life Sciences manufactures ELISA kits and immunoassays for cytokine, biomarker, and signaling research, with strength in neurobiology and immunology. Directly competes in ELISA kit sales to academic and biotech customers with comparable product specifications and validated quality.
- Cell Signaling Technology (CST): CST is a US-based manufacturer of high-validation antibodies, ELISA kits, and immunoassay reagents for cell signaling, cancer biology, and biotherapeutic research. Directly competes on premium-grade ELISA kits with strong validation, similar to Krishgen's KRIBIOLISA line, with comparable ICH/regulatory documentation standards.
Emerging players
- Elabscience: Elabscience is a China-based manufacturer with a 3,000+ SKU catalog of ELISA kits and reagents covering cytokines, biomarkers, and biotherapeutics at highly competitive price points. Overlaps heavily with Krishgen on catalog breadth and value-priced positioning, particularly for global biopharma buyers in cost-sensitive markets — a competitive head-to-head on price/turnaround.
Broad incumbents
- Thermo Fisher Scientific: Thermo Fisher, through Invitrogen and Thermo Scientific brands, offers Novex and Pierce ELISA kits for bioprocess QC (HCP, HCDNA), biotherapeutics PK/ADA, and cytokine biomarker research. As a broad-incumbent life sciences platform, it competes with Krishgen across most ELISA categories while also distributing competing products via Fisher Scientific channel.
- Merck Millipore Sigma: Merck KGaA / MilliporeSigma manufactures and sells ELISA kits (e.g., HCP, BioReliance) for bioprocess impurity testing and bioanalytical method development. Its BioReliance bioprocess testing services and HCP ELISA kits directly compete with Krishgen's KRIBIOLISA bioprocess portfolio, particularly for CHO and E. coli systems.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat6 records
Key risks6 records
Key highlights7 records
Customer concentration
Krishgen BioSystems social profiles
Digital presenceKrishgen BioSystems compliance and trust
Trust signalCompliance8 records
Krishgen BioSystems financial estimates
Financial estimateRevenue estimate
Valuation estimate
Krishgen BioSystems leadership team
Management profileNumber of profiles
Profiles6 records
Krishgen BioSystems funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Krishgen BioSystems M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Krishgen BioSystems
What does Krishgen BioSystems do?
Krishgen BioSystems manufactures ELISA-based immunoassays, biochemical detection tools, molecular biology reagents, and recombinant enzymes for life-science research, biologics development, and bioprocess quality control. It also distributes third-party life-science products in India and provides custom assay development services for specialized therapeutic targets and sample types.
Is Krishgen BioSystems a public or private company?
Krishgen BioSystems is a private company. It is classified as family owned and is currently operating.
When was Krishgen BioSystems founded?
Krishgen BioSystems was founded in 2003. It employs 101 to 250 people.
Where is Krishgen BioSystems based?
Krishgen BioSystems is headquartered in Mumbai, India, in the Asia region.
How does Krishgen BioSystems make money?
Four revenue lines are on record. ELISA Kit Sales are the primary driver. The others are custom Assay Development Services, distribution of International Products and molecular Biology Reagents.
Who are Krishgen BioSystems's main competitors?
Direct peers on record are Cayman Chemical, RayBiotech, Abcam (Danaher), Bio-Techne, Boster Bio, Enzo Life Sciences and Cell Signaling Technology (CST). Elabscience is listed as an emerging player. Broad incumbents are Thermo Fisher Scientific and Merck Millipore Sigma.
Does Krishgen BioSystems have an API?
No public API is recorded for Krishgen BioSystems.
What industry is Krishgen BioSystems in?
Krishgen BioSystems's product category is ELISA Immunoassay Kits. Its primary akta.pro industry code is HLAGAIAI, Reagents, Chemicals & Assay Kits (Buffers, Antibodies, ELISA, Enzymes), with a secondary code of HLAAAIAB, Antibody Discovery & Engineering Platforms (display tech, bispecifics, Fc engineering). Its NAICS code is 325413 and its SIC code is 2835.