Avidity
Avidity LLC is a privately held Colorado-based molecular biology reagents company that develops the patented AviTag site-specific biotinylation platform, selling BirA enzyme kits, engineered E. coli strains, expression vectors, and pre-biotinylated reporter proteins to life-science researchers and pharmaceutical companies worldwide.
- Company typePrivate
- Founded1996
- HeadquartersAurora, United States
- Headcount1–10
- GTM typeB2B
- OfferingHardware or Manufacturing
What Avidity does
Avidity LLC is a privately held molecular biology reagents company founded in 1996 in Aurora, Colorado, that develops, manufactures, and distributes the AviTag biotinylation technology platform. AviTag is a patented 15-amino-acid peptide tag (GLNDIFEAQKIEWHE) that, when fused to a target protein, is recognized by the E. coli biotin ligase BirA for site-specific enzymatic biotinylation. The company sells a complete workflow including BirA enzyme kits (standard, bulk, and lyophilized formats), supporting biotin solutions, engineered E. coli strains for in vivo biotinylation, AviTag expression vectors (pAN/pAC and ATUM p3A series), a C-terminal AviTag monoclonal antibody, control plasmids and proteins, and a growing catalog of pre-biotinylated reporter proteins such as Gaussia luciferase and CFP variants. The technology underpins protein purification, biosensors, proximity assays, drug screening, and diagnostic workflows.
The business operates a product-led, e-commerce-centric model with unit-priced reagents sold directly through avidity.com and through regional distributors in Japan, China, India, Korea, and the US, supplemented by technology sublicensing of AviTag rights originally obtained from Affymax. Pricing spans $45 to $980 per unit, with lyophilized kit formats specifically designed for geographies where frozen cold-chain delivery is unreliable. Customer concentration is split between a long tail of academic and industrial life-science researchers (in 30+ countries) and a deeper enterprise engagement channel, with AviTag reportedly in use by eight of the world's top ten pharmaceutical companies.
The company is founder-led (Millard Cull, Larry Lansing, Dr. Ron Gill, Dr. Mark Seville) and has operated as an independent, self-funded LLC for nearly three decades, with no disclosed institutional investment, M&A, or leadership transitions in the available record. Documented external engagements include a long-running co-development partnership with Prolume, Ltd. (bioluminescent proteins), an integration partnership with ATUM (Electra Vector cloning system), and a portfolio of distributor relationships that together constitute Avidity's primary growth and reach mechanisms.
Avidity firmographics
Firmographics- Name
- Avidity
- Legal name
- Avidity LLC
- Website
- https://avidity.com
- Company type
- Private
- Founded year
- 1996
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Short description
- Avidity LLC is a privately held Colorado-based molecular biology reagents company that develops the patented AviTag site-specific biotinylation platform, selling BirA enzyme kits, engineered E. coli strains, expression vectors, and pre-biotinylated reporter proteins to life-science researchers and pharmaceutical companies worldwide.
- Ownership category
- akta.pro rank
Avidity industry classification
Industry- Product category
- Molecular Biology Reagents
- NAICS
- Research and Development in Biotechnology (except Nanobiotechnology) (541714)
- SIC
- In Vitro & In Vivo Diagnostic Substances (2835)
- akta.pro primary industry
- Reagents, Chemicals & Assay Kits (Buffers, Antibodies, ELISA, Enzymes) (HLAGAIAI)
- akta.pro secondary industry
- Biomarker Assay & Reagent Development (LDT/IVD assay design, antibodies/standards/controls) (HLAAAMAL)
Keywords
Where Avidity is headquartered
LocationHeadquarters
- HQ city
- Aurora
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Avidity business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Personnel, Operations, Supply Chain, Technology or R&D, Marketing or Sales, Infrastructure
Revenue model
- Product Sales: Direct sales of molecular biology reagents including BirA enzyme kits, biotin solutions, E. coli strains, AviTag vectors, antibodies, and biotinylated proteins via e-commerce platform. One-time product purchases with standard pricing for individual items.
- Technology Licensing: Sublicenses rights to use the AviTag technology to other companies. Original exclusive rights obtained from Affymax by founder Millard Cull.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Unit Pricing | Pay-as-you-go | AbC Monoclonal Antibody - $200.00 |
| Unit Pricing | Pay-as-you-go | BirA500 Standard Reaction Kit - $250.00 |
| Unit Pricing | Pay-as-you-go | Bulk BirA Reaction Kit - $980.00 |
| Unit Pricing | Pay-as-you-go | BirA500-RT Lyophilized Kit - Standard pricing |
| Unit Pricing | Pay-as-you-go | BIO-200 Biotin Solution - $45.00 |
| Unit Pricing | Pay-as-you-go | BIO-500 Biotin Solution - $90.00 |
| Unit Pricing | Pay-as-you-go | BIS-300 Control Protein Kit - $150.00 |
| Unit Pricing | Pay-as-you-go | AVB100 Glycerol Stock - $250.00 |
| Unit Pricing | Pay-as-you-go | EVB100 Electro-competent Cells - $195.00 |
| Unit Pricing | Pay-as-you-go | AVB101 E. coli B Strain - $250.00 |
| Unit Pricing | Pay-as-you-go | p3A-Rha-C-Avtg-RE Vector - $225.00 |
| Unit Pricing | Pay-as-you-go | Electra Cloning Kit - $200.00 |
| Unit Pricing | Pay-as-you-go | PANs Plasmid Set - $450.00 |
| Unit Pricing | Pay-as-you-go | PACs Plasmid Set - $450.00 |
| Unit Pricing | Pay-as-you-go | BIP-300 Positive Control Plasmid - $150.00 |
Go-to-market motion1 record
Distribution channels2 records
Marketing channels4 records
Avidity product offering
Product offeringCore offering
Avidity develops and sells molecular biology reagents built around its proprietary AviTag technology, a 15 amino acid peptide tag that enables site-specific enzymatic biotinylation of proteins using the E. coli BirA biotin ligase. The product line includes BirA enzyme reaction kits, E. coli cell strains for in vivo biotinylation, AviTag expression vectors, the AbC monoclonal antibody, biotin solutions, and biotinylated fluorescent and luciferase reporter proteins, sold primarily to life science researchers and pharmaceutical companies.
Product overview
Avidity is a molecular biology reagents company offering the AviTag biotinylation technology platform. The core product line consists of BirA biotin-protein ligase enzymes (in standard, bulk, and lyophilized formats) for in vitro biotinylation, E. coli cell strains (AVB100, AVB101, AVB99) for in vivo biotinylation, and expression vectors (pAN/pAC series and ATUM p3A vectors) for cloning AviTag fusion proteins. Supporting products include control reagents (BIP-300 plasmid, BIS-300 protein kit), the AbC monoclonal antibody for AviTag detection/purification, biotin solutions (BIO-200, BIO-500), and the Electra Cloning Kit for use with p3A vectors. Additionally, the company offers biotinylated fluorescent proteins (Twinkle, Holly, Dasher CFP variants) and Streptavidin-fusion proteins combining bioluminescence with biotin interaction capabilities.
Differentiator
Problem solved
Functional benefit
Products and services
- BirA Biotin-Protein Ligase Reaction Kits
- E. coli Strains for In Vivo Biotinylation
- AviTag Expression Vector Sets
- AbC Monoclonal Antibody Against AviTag
- Biotin Solutions (BIO-200 and BIO-500)
- BIS-300 Control Protein Kit
- BIP-300 Positive Control Plasmid
- Electra Cloning Kit
- Biotinylated Recombinant Proteins
- AviTag Technology Sublicensing
Quantifiable outcome
- Biotinylation rate is 2x faster than natural E. coli BCCP substrate
- +1 more outcomes
Companies that use Avidity
Customer profileNamed customers1 record
Segments2 records
Ideal customer profiles2 records
Avidity technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature6 records
Avidity partnerships and signals
Strategic signalPartnerships
Eight partnerships are on record, tiered core and minor.
- Atum (formerly DNA 2.0)coreAvidity partnered with Atum to offer the Atum Electra Vector System for easy cloning from PCR products into AviTag vectors. The p3A vector series utilizes this technology, allowing researchers to clone target genes into linearized AviTag plasmids using SapI restriction enzyme.
- Prolume, Ltd.minorAvidity collaborated with Prolume, Ltd. beginning in 2004 to use AviTag technology in conjunction with Prolume's Gaussia luciferase and Green Fluorescent Proteins (GFP). The first Gaussia-AviTag product was released in November 2007, combining bioluminescence technology with site-specific biotinylation.
- Cosmo Bio Co., Ltd.minorJapanese distributor for Avidity products, serving customers in Japan.
- Biohub International Trade Co. Ltd.minorChinese distributor for Avidity products, serving customers in China.
- DAKEWE BIOTECH Co.minorChinese distributor for Avidity products based in Shenzhen.
- Labex CorporationminorIndian distributor for Avidity products, serving customers in India.
- Kim & Friends, Inc.minorKorean distributor for Avidity products, serving customers in Korea.
- SR TechnologiesminorUS-based distributor for Avidity products, located in Corona, California.
Scale indicators3 records
Recent moves5 records
Expansion highlights4 records
Avidity competitors and assessment
Company assessmentPeers
Direct peers
- New England Biolabs (NEB): Major specialty reagent company selling enzymes, tagging tools (including the SNAP-tag alternative), and protein biotinylation reagents to life science researchers. Directly comparable as a specialist provider of molecular biology enzymes and protein-tagging workflow tools.
- Promega Corporation: Specialty reagent company with a competing HaloTag protein-tagging platform and broad biotin/streptavidin product lines serving pharma and academic protein research. Highly comparable as a competitor for protein labeling and affinity purification workflows.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat4 records
Key risks6 records
Key highlights7 records
Customer concentration
Avidity social profiles
Digital presenceAvidity financial estimates
Financial estimateRevenue estimate
Valuation estimate
Avidity leadership team
Management profileNumber of profiles
Profiles4 records
Avidity funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Avidity M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Avidity
What does Avidity do?
Avidity develops and sells molecular biology reagents built around its proprietary AviTag technology, a 15 amino acid peptide tag that enables site-specific enzymatic biotinylation of proteins using the E. coli BirA biotin ligase. The product line includes BirA enzyme reaction kits, E. coli cell strains for in vivo biotinylation, AviTag expression vectors, the AbC monoclonal antibody, biotin solutions, and biotinylated fluorescent and luciferase reporter proteins, sold primarily to life science researchers and pharmaceutical companies.
Is Avidity a public or private company?
Avidity is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was Avidity founded?
Avidity was founded in 1996. It employs 1 to 10 people.
Where is Avidity based?
Avidity is headquartered in Aurora, United States, in the North America region.
How does Avidity make money?
Two revenue lines are on record. Product Sales are the primary driver. The others are technology Licensing.
Who are Avidity's main competitors?
Thermo Fisher Scientific is listed as a peer. Direct peers are New England Biolabs (NEB) and Promega Corporation.
Does Avidity have an API?
No public API is recorded for Avidity.
What industry is Avidity in?
Avidity's product category is Molecular Biology Reagents. Its primary akta.pro industry code is HLAGAIAI, Reagents, Chemicals & Assay Kits (Buffers, Antibodies, ELISA, Enzymes), with a secondary code of HLAAAMAL, Biomarker Assay & Reagent Development (LDT/IVD assay design, antibodies/standards/controls). Its NAICS code is 541714 and its SIC code is 2835.