Caress Flow

What Caress Flow does

Caress Flow S.r.l. is an Italian medical technology company founded by Dr. Leone Condemi at Urbino Hospital that develops and commercializes a patented non-invasive medical device system for treating vulvo-vaginal atrophy (VVA) and related female intimate health conditions. The core technology combines high-concentration molecular oxygen (approximately 93-96%) with low molecular weight hyaluronic acid delivered through disposable cannulas in 15-minute sessions, following a protocol of five treatments at 14-day intervals. The therapy reactivates microcirculation and promotes neoangiogenesis, with reported results lasting 12-18 months and over 70% of patients reporting concrete results after the first session. The system is particularly differentiated for patients contraindicated for hormone-based therapies, notably breast cancer survivors experiencing treatment-induced menopause.

The company sells its devices to gynecologists, obstetricians, and medical professionals who administer treatments in their clinics, generating revenue from initial hardware sales plus recurring consumable revenue from disposable cannulas. Its go-to-market relies on medical congress participation across Europe and internationally, a free 1-month trial program for physicians, and continuing medical education (ECM) courses featuring key opinion leaders such as Prof. Angelo Cagnacci and Dr. Filippo Murina. The company has a 220+ clinic footprint in Italy, 380+ trained physicians, and 5,400+ patients treated, with growing international presence in Spain, France, Japan, and the United States supported by EU regional development grants (POR-FESR and Fondo Starter, totaling approximately €468,000 in project value). Caress Flow is currently developing two home-use device variants to extend the therapy into patient self-administration under medical prescription.

Name

Caress Flow

Legal name

Caress Flow S.r.l.

Website

https://caressflow.com

Company type

Private

Founded year

2017

Operating status

Operating

Headcount range

11–50 employees

Short description

Caress Flow S.r.l. is an Italian medical technology company that develops and sells a patented device delivering molecular oxygen and hyaluronic acid to treat vulvo-vaginal atrophy. It sells to gynecologists and medical clinics across Italy, Spain, France, Japan, and the USA.

Ownership category

akta.pro rank

Headquarters

HQ city

Bologna

HQ country

Italy

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Supply Chain, Marketing or Sales, Personnel, Operations

Revenue model

1. Medical Device Sales: Sale of CARESS FLOW medical devices to clinics and medical practices for treatment of vulvo-vaginal atrophy and related conditions.
2. Consumables Revenue: Ongoing revenue from disposable cannulas and consumables required for each treatment session, generating recurring revenue from installed device base.
3. Treatment Protocol Licensing: Professional treatment protocol prescribed by physicians and performed by specialized personnel, suggesting a per-treatment or subscription model for medical practices.

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels7 records

Core offering

Caress Flow develops and sells a patented medical device system that delivers high-concentration molecular oxygen (approximately 93-96%) combined with low molecular weight hyaluronic acid through a disposable cannula to treat vulvo-vaginal atrophy and related female intimate health conditions. The treatment is administered in 15-minute outpatient sessions, typically as a 5-session protocol at 14-day intervals, and is offered to clinics and medical professionals as both a clinical-use system and a home-use device variant for patient self-treatment under medical prescription.

Product overview

CARESS FLOW is a unified medical device system consisting of the core CARESS FLOW treatment system and two home-use medical device variants. The main system delivers molecular oxygen and hyaluronic acid through a proprietary protocol (5 sessions at 14-day intervals, 15 minutes each) for treating vulvo-vaginal atrophy and related female intimate health conditions. The home-use devices extend this therapy for patient self-treatment under medical supervision.

Differentiator

Problem solved

Functional benefit

Products and services

• CARESS FLOW System A medical device system for vulvo-vaginal treatments that delivers high-concentration molecular oxygen (93-96%) combined with low molecular weight hyaluronic acid through a disposable cannula, providing non-invasive therapy for vulvo-vaginal atrophy and related conditions affecting female intimate health. Designed for use in medical clinics and practices by gynecologists and women's health professionals.
• CARESS FLOW Home Use Devices Two new medical devices engineered for home use self-treatment of vulvo-vaginal atrophy (AVV) and dermatological conditions, designed for patient self-administration under medical prescription, extending the in-clinic CARESS FLOW therapy to the home setting.

Quantifiable outcome

• Over 70% of patients reported concrete results after the first treatment session
• +2 more outcomes

Named customers6 records

Segments4 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

Five partnerships are on record, tiered core and minor.

• University of Ancona (Politecnica delle Marche)coreStrategic or Co-development PartnerInitial research collaboration with University of Ancona for first clinical studies and validation of the CARESS FLOW technology. University showed spontaneous interest in the research following initial positive results.
• FEDER.S.P.eV.minorStrategic or Co-development PartnerFederation of Health Retirees (Doctors, Veterinarians and Pharmacists - Widows and Survivors) collaborating on the Progetto Percorso Donna initiative in Brindisi to promote CARESS FLOW treatment among cancer patients.
• AISA AssociationminorStrategic or Co-development PartnerAssociation operating in social and health voluntary service, co-developing the Progetto Percorso Donna initiative with FEDER.S.P.eV. and Dr. Poddi for breast cancer patient support using CARESS FLOW protocol.
• Prof. Angelo CagnaccicoreStrategic or Co-development PartnerDirector of Obstetrics and Gynecological Clinic at IRCCS-San Martino Hospital in Genoa. Key opinion leader conducting webinars and presenting at national congresses (A.G.E.O.) on CARESS FLOW effectiveness for induced menopause in breast cancer patients.
• Dr. Filippo MurinacoreStrategic or Co-development PartnerGynecologist, expert in vulvar pathology and vulvodynia, Founder and Scientific Director of Italian Vulvodynia Onlus Association. Course speaker for ECM training and webinar presenter on vulvo-vaginal atrophy topics.

Scale indicators9 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Cynosure (Hologic) - MonaLisa Touch: Cynosure markets MonaLisa Touch, a fractional CO2 laser system specifically cleared for vulvo-vaginal atrophy and genitourinary syndrome. It is the most widely adopted clinic-based VVA device competitor to Caress Flow, targeting the same gynecologists with a similar capex-plus-recurring model.
• Viveve Medical: Viveve developed a cryogen-cooled monopolar RF system (Viveve System) for vaginal laxity and sexual function in OB/GYN practices. Direct competitor in the clinic-based device category targeting overlapping indications and physician customers.
• BTL Group - Ultra Femme 360: BTL's Ultra Femme 360 is a 360-degree RF device used in gynecology and medical-aesthetics clinics for vaginal rejuvenation and atrophy-related symptoms. Direct competitor with an established international sales footprint in the same physician channel as Caress Flow.
• InMode - EmpowerRF: InMode's EmpowerRF platform (including Morpheus8V and VTone) provides RF-based and microneedling treatments for vaginal atrophy and pelvic floor dysfunction. Direct competitor offering a multi-modality women's health device suite to gynecology and aesthetics clinics.
• Fotona - IntimaLase: Fotona's IntimaLase (Er:YAG) and similar gynecological laser protocols are sold to OB/GYN clinics for VVA and stress urinary incontinence. Direct competitor using a laser-based modality in the same physician-installed-base model as Caress Flow.
• Sciton - diVa: Sciton's diVa hybrid fractional laser is a clinic-based device for vaginal atrophy and genitourinary syndrome of menopause. Direct competitor using a different modality (laser) but the same physician channel and indication.
• Alma Lasers - FemiLift: Alma's FemiLift is a CO2 laser system marketed for vaginal atrophy, rejuvenation, and stress urinary incontinence in OB/GYN and medical-aesthetics practices. Direct competitor in the clinic-based VVA device category, sold through the same physician channel as Caress Flow.

Broad incumbents

• Hologic: Hologic is a large women's-health medical device company (owner of Cynosure) with a broad portfolio spanning mammography, NovaSure endometrial ablation, MyoSure hysteroscopic tissue removal, and the MonaLisa Touch laser. Broad incumbent offering overlapping VVA capability as part of a much wider women's-health portfolio.
• CooperSurgical: CooperSurgical is a major women's-health medical device and fertility company (part of CooperCompanies) with products spanning gynecology, IVF, and obstetrics. Broad incumbent whose physician relationships and capital base could be leveraged to enter the VVA device category competitively.

Emerging players

• Bonafide Health: Bonafide Health markets Revaree, a hyaluronic acid vaginal moisturizer, and other consumer products for menopause-related symptoms including VVA. Emerging player addressing the same patient indication through an OTC consumer channel rather than a physician-installed medical device.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat3 records

Key risks7 records

Key highlights7 records

Customer concentration

• Facebookfacebook.com/CaressFlowItalia
• LinkedInlinkedin.com/company/caress-flow

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Caress Flow