What BioRep does

BioRep S.r.l. is a Milan-based biobanking and life sciences services company founded in 2003 and operating as a wholly-owned subsidiary of Gruppo Sapio (parent: Sapio Life S.r.l.). The company provides a vertically integrated stack spanning cryopreservation, GMP and non-GMP biobanking, molecular biology, next-generation sequencing, transport and logistics, and Bio-Digital CRO services, serving pharmaceutical companies, clinical research organizations, hospitals, and research institutions across approximately 50 countries. Technical infrastructure is anchored by CE-IVD and FDA-approved NGS workflows on the Illumina VeriSeq NIPT Solution v2 and NextSeq 550Dx platforms, and BioRep holds ISO 21973:2020 accreditation for the transport of cellular therapy products. Operationally, the company manages approximately 9 million samples, has built 40 biobanks in Italy, performs 80,000 genetic tests cumulatively, and ships 200 collection kits daily, supported by a workforce of 11-50 employees and a deliberated capital stock of €4,000,000.

The business model combines B2B service revenue (per-sample biobanking fees, sequencing project contracts, CRO engagements, and logistics agreements) with B2C consumer revenue from the NATIVA® non-invasive prenatal testing (NIPT) line and the exclusive Italian distribution of Atlas Biomed DNA and microbiome tests. A partnership stack with Inaphaea BioLabs/ValiRx, IRCCS Ospedale San Raffaele, Advice Pharma Group, Axxam, and the HI-BAD consortium extends the platform into pharma R&D services, clinical research anchoring, digital therapeutics, and AI/ML-driven biomarker discovery in neurodevelopmental disorders and prediabetes. Management is led by CEO Michele Piovella, with Daniela Sica as Chief Commercial Officer and Simone Agrati as Sales & Marketing Manager. BioRep functions as a mid-sized, specialized node in the European biobanking and reproductive/molecular diagnostics value chain rather than a mass-market consumer genomics player, with growth driven by adjacent vertical expansion (notably cellular therapy logistics) and partnership-led service-line extension.

Name

BioRep

Legal name

BioRep S.r.l.

Website

https://biorep.it

Company type

Private

Founded year

2003

Operating status

Operating

Headcount range

11–50 employees

Short description

BioRep S.r.l., a Milan-based subsidiary of Gruppo Sapio, provides biobanking, cryopreservation, NGS sequencing, transport logistics, and Bio-Digital CRO services to pharma, hospitals, and research institutions across ~50 countries, alongside the NATIVA® NIPT consumer line and Atlas DNA/microbiome distribution in Italy.

Ownership category

akta.pro rank

Product category

Biobanking and Contract Research Services

NAICS

Medical Laboratories (621511), Scientific Research and Development Services (5417), Research and Development in Biotechnology (except Nanobiotechnology) (541714)

SIC

Services-Medical Laboratories (8071), Services-Commercial Physical & Biological Research (8731), In Vitro & In Vivo Diagnostic Substances (2835)

akta.pro primary industry

Genetic & Prenatal Testing Laboratories (HLAFAMAH)

akta.pro secondary industry

Bioanalytical Testing (PK/ADA/NAb) (HLAGADAA)

Keywords

• Biobanking services
• Cryopreservation storage
• NGS sequencing
• Non-invasive prenatal testing
• Contract research services

Headquarters

HQ city

Milan

HQ country

Italy

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Technology or R&D, Operations, Infrastructure, Marketing or Sales, Supply Chain

Revenue model

1. Biobanking & Cryopreservation Services: Recurring and long-term managed services for biological sample storage (third-party and GMP) with disaster recovery, including logistics and transport management of biological materials.
2. Bio-Digital CRO and Research Network Management: Professional services for end-to-end management of clinical research networks and contract research services for biotech and pharma, including lab services (cellular and molecular biology, NGS sequencing).
3. Genetic Testing Services (NIPT NATIVA® and Atlas Microbiome/DNA): Per-test fee revenue from prenatal screening (NATIVA® / NATIVA® NEXT) and direct-to-consumer microbiome/DNA tests distributed in Italy.
4. Turnkey Storage Centers & Hardware Products: One-time hardware and equipment sales: turnkey storage centers, cryobiological/cryogenic containers, programmable rate freezers, monitoring/control systems, oxygen sensors, cryosurgery devices, consumables, and PPE.
5. Pharmaceutical Warehouse / Deposito Farmaceutico: Specialized pharmaceutical warehousing service as a regulated logistics and storage offering.

Pricing tiers

Go-to-market motion4 records

Distribution channels4 records

Marketing channels8 records

Core offering

BioRep is a Biological Resource Centre and bio-digital CRO providing biobanking, GMP and non-GMP cryopreservation, ISO-certified transport and logistics, molecular biology and NGS sequencing services, turnkey biobank design, and contract research services to biotech, pharma, and research institutions across 50 countries. The company also distributes its own NATIVA non-invasive prenatal screening (NIPT) tests directly to consumers and resells Atlas DNA and Atlas Microbiome tests in Italy under a partnership with Atlas Biomed.

Product overview

BioRep is not a single unified SaaS product but a platform-plus-modules services company built around a Biological Resource Centre: it combines a biobanking core (collection, cryopreservation, GMP storage, transport, disaster recovery, biobank "turn-key" design) with a clinical-research laboratory (cellular biology, molecular biology, NGS sequencing), a contract research arm (International Full-Service Bio-Digital CRO serving 50 countries with ~9M samples stored), and a portfolio of branded genetic tests. On top of this platform sit branded modules including the NATIVA NIPT family (with NATIVA® NEXT powered by Illumina VeriSeq™ NIPT Solution v2 on a NextSeq™ 550Dx), the Atlas DNA and Atlas Microbiome consumer tests distributed in Italy under partnership with Atlas Biomed, and a research/AI platform — the Lombardy HI-BAD project — building AI/ML biomarker tools and a Regional Biological Resources Centre (CRRB). The offering is further extended by a Digital Therapeutics (DTx / Terapie Digitali) partnership with Advice Pharma Group, and is supported by a hardware and consumables catalog (cryogenic containers, controlled-rate freezers, monitoring systems, oxygen sensors, cryosurgery equipment, disposables, PPE) and consulting for biobank design.

Differentiator

Problem solved

Functional benefit

Brands

• NATIVA®: Non-invasive prenatal screening test (NIPT) range branded by BioRep, including the NATIVA® NEXT product using VeriSeq™ NIPT Solution v2 technology from Illumina Inc.

Products and services

• Biobanking and Biological Resource Center Services Collection, conservation, and long-term management of approximately 9 million biological samples on behalf of third parties and research networks, with operations spanning 50 countries and ~40 biobanks built in Italy. Targets biotech, pharma, CROs, hospitals, universities, and clinics.
• International Full Service Bio-Digital CRO End-to-end contract research services for clinical and translational research sponsors worldwide, covering logistics, biological sample storage, laboratory analysis, and data handling across the study lifecycle. Targets biotech, pharma, and research institutions across 50 countries.
• Transport and Logistics Management for Biological Samples End-to-end transport and cold-chain logistics for biological samples, certified under ISO 21973:2020 (DNV) for the transport of biological material intended for therapeutic use. Targets research institutions, biotech, and pharma.
• Pharmaceutical Warehouse Specialized regulated storage of pharmaceutical products, complementing BioRep's biological sample storage capabilities. Targets pharmaceutical and life sciences customers.
• Third-Party Cryopreservation (non-GMP) Cryopreservation of biological samples on behalf of third parties under standard (non-GMP) conditions, including disaster recovery planning. Targets research and clinical sample owners.
• GMP Cryopreservation Good Manufacturing Practice (GMP)-compliant cryopreservation of biological samples intended for therapeutic use, with disaster recovery planning. Targets clinical, biotech, and pharma sponsors requiring regulated storage.
• Disaster Recovery Plan for Biobanks Backup and continuity services for biological sample collections, providing secure secondary storage and chain-of-custody. Targets biobank owners and clinical research sponsors.
• Cellular Biology Laboratory Services Cell biology laboratory services supporting research and clinical applications, including cell-based assays and analysis for translational research programs. Targets biotech, pharma, and research institutions.
• Molecular Biology Laboratory Services High-quality molecular biology services including nucleic acid purification, primer selection, amplification, sequencing, genotyping, molecular oncology, pharmacogenetics, nutrigenomics, and custom method development, with participation in national and international external quality assessment programs. Targets biotech, pharma, and research institutions.
• NGS Sequencing Services Next-Generation Sequencing services using Illumina technology, including whole-genome non-invasive prenatal testing and other diagnostic panels on a CE-IVD/FDA-approved NextSeq 550Dx sequencer. Targets clinical labs, hospitals, and research sponsors.
• Turn-key Storage Centers Design and construction of "turn-key" biological sample storage centers, including facility layout, equipment, and operational setup. BioRep has built ~40 such centers in Italy. Targets hospitals, universities, and research institutions.
• NATIVA NEXT Non-Invasive Prenatal Test (NIPT) Whole-genome non-invasive prenatal screening test detecting trisomies 13/18/21, sex chromosome aneuploidies, rare autosomal aneuploidies, and CNVs ≥7 Mb, run on Illumina's CE-IVD and FDA-approved VeriSeq NIPT Solution v2 and NextSeq 550Dx. Targets expectant mothers in Italy, sold via nativaprenatale.it.
• NATIVA Prenatal Screening Range BioRep's branded range of non-invasive prenatal screening tests (NIPT) for expectant mothers; BioRep was the first company to introduce a fully CE-IVD-certified NIPT on the Italian market using Illumina's VeriSeq NIPT system. Targets Italian consumers (expectant mothers).
• Atlas DNA Test (Italy distribution) DNA screening test analyzing more than 400 characteristics (vitamin/micronutrient metabolism, food intolerances, dietary recommendations, sports injury risk, ancestry, and individual traits), based on Illumina technology, with results accessible via digital platforms and a dedicated app. Distributed in Italy by BioRep under partnership with Atlas Biomed. Targets Italian consumers.
• Atlas Microbiome Test (Italy distribution) Gut microbiome test with 22 health reports covering diversity of bacterial populations, probiotic proportions, and micronutrient production, providing personalized dietary recommendations. Distributed in Italy by BioRep under partnership with Atlas Biomed. Targets Italian consumers.
• Cryobiological and Cryogenic Containers Cryobiological and cryogenic storage containers sold as part of BioRep's hardware catalog for biobank and laboratory customers.
• Programmable Controlled-Rate Freezers Programmable controlled-rate freezers used in cryopreservation workflows, sold as part of BioRep's hardware catalog for biobank and laboratory customers.
• Monitoring and Control Systems Monitoring and control systems for biobank and storage facilities, including temperature and environmental monitoring, sold as part of BioRep's hardware catalog.
• Sub-Oxygenation Monitoring (Oxygen Sensors) Oxygen-level sensors for monitoring sub-oxygenation conditions in cryogenic and cryobiological environments, sold as part of BioRep's hardware catalog.
• Cryosurgery Equipment Cryosurgery equipment and solutions distributed within BioRep's hardware catalog. Targets clinical and surgical users.
• Biobanking Consumables Consumables for biobanking and laboratory workflows, including approximately 200 collection kits managed daily. Targets biobank and laboratory customers.
• Personal Protective Equipment (PPE) Personal protective equipment distributed by BioRep for laboratory and clinical use, sold as part of the hardware catalog.

Quantifiable outcome

• Approximately 9,000,000 biological samples conserved
• +4 more outcomes

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration1 record

AI capability7 records

Feature6 records

Partnerships

Nine partnerships are on record, tiered high - flagship clinical collaboration in nipt, flagship - flagship cross-border european expansion partnership, high - integrated dtx offering partnership, medium - research consortium partnership, medium - regional r&d consortium partnership, high - key consumer-test distribution partnership, high - core technology platform partner, low - industry association membership and flagship - parent company and governance entity.

• IRCCS Ospedale San Raffaelehigh - flagship clinical collaboration in niptStrategic or Co-development Partner · 7 April 2025BioRep and IRCCS Ospedale San Raffaele expanded their collaboration in prenatal screening in April 2025. BioRep patients who take the fetal DNA test gain access to a new second-level psychological and genetic counseling service from Ospedale San Raffaele (in addition to pre- and post-test genetic counseling already included in the NIPT service). Counseling is delivered remotely via Ospedale San Raffaele's telemedicine platform.
• Inaphaea BioLabs Limited (ValiRx Plc)flagship - flagship cross-border european expansion partnershipGTM or Marketing Partner · 14 October 2024Co-Marketing Agreement signed in October 2024. Under the agreement, Inaphaea provides its high-throughput drug screening services and patient-derived cell (PDC) services to BioRep's customer network in continental Europe, while BioRep provides backup sample storage, logistics, and molecular biology services in continental Europe. Both parties are entitled to a percentage of royalties on services or sales from contracts introduced by the other party, and both will jointly promote their respective services.
• Advice Pharma Group S.r.L.high - integrated dtx offering partnershipStrategic or Co-development Partner · 1 January 2022The Sapio Group, through its subsidiary BioRep S.r.l., and Advice Pharma Group signed a partnership agreement aimed at creating an integrated offering in the development of Digital Therapies (DTx) and research services. BioRep and Advice Pharma jointly promote the combined DTx / research services offering at industry events such as the BIO International Convention.
• Axxam (iPSLight Project Consortium)medium - research consortium partnershipStrategic or Co-development Partner · 9 December 2019BioRep is a partner in the all-Lombardy iPSLight research project, led by Axxam, with IMS, the University Vita-Salute and the CNR Institute of Neuroscience. The project aims to develop reprogrammed human stem cells for in vitro modeling of neurodegenerative diseases such as Parkinson's.
• Advice Pharma srl, Diabs Srl, and IRCCS E. Medea (HI-BAD Project Consortium)medium - regional r&d consortium partnershipStrategic or Co-development Partner · 8 October 2019BioRep is the leader of the HI-BAD project, one of the top 11 projects admitted to the Lombardy regional "Call HUB Research and Innovation" out of 78 submissions. The project, proposed in collaboration with Advice Pharma srl, Diabs Srl and IRCCS E. Medea, involves two clinical studies (neurodevelopmental disorders and pre-diabetic subjects) requiring acquisition of multimodal data and development of AI / machine learning tools, with the goal of creating a Regional Biological Resources Centre (CRRB).
• Atlas Biomedhigh - key consumer-test distribution partnershipChannel Partner/ Reseller/ Distributor · 1 January 2019Atlas DNA and Atlas Microbiome tests, based on Illumina technology, are distributed in Italy through the collaboration between BioRep and Atlas Biomed. The combined tests allow more than 400 different characteristics to be considered, providing a detailed picture of health status, with results accessible via digital platforms and a dedicated app.
• Illumina Inc.high - core technology platform partnerTechnology or Integration · 1 January 2019BioRep uses Illumina's VeriSeq™ NIPT Solution v2 and NextSeq™ 550Dx sequencer for its NATIVA® NEXT non-invasive prenatal test. The technology is CE-IVD and FDA approved for NGS analysis of diagnostic panels. BioRep was the first company to introduce a fully CE-IVD-certified NIPT to the Italian market with Illumina.
• Cluster Lombardo Life Sciences (Lombardia Life Sciences)low - industry association membershipOthers · 1 January 2019BioRep is a member ("socio") of the Lombardia Life Sciences Cluster, a regional life sciences industry association that connects research centers, biotech, pharma, and academic actors in Lombardy.
• Gruppo Sapio / Sapio Life S.r.l.flagship - parent company and governance entityOthers · 1 January 2003BioRep S.r.l. is a company of the Sapio Group, subject to the direction and coordination of Sapio Life S.r.l. The Sapio Group is a large Italian industrial group whose purpose includes advancing biotech research and life sciences; BioRep operates as its biotech arm providing biological resource center services, lab services, and DNA sequencing.

Scale indicators8 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Cryoport Systems: US-based provider of temperature-controlled cold-chain logistics and cryogenic storage for life sciences, with strong focus on cell & gene therapy and reproductive medicine. Comparable to BioRep's transport, cryopreservation, and biobanking offerings, particularly for therapeutic biological materials.
• BioIVT: Supplier of biological specimens, including biobanking and specialty sample products for research and diagnostics. Direct peer to BioRep's biological resource center and CRO research services for biotech and pharma clients.
• Hamilton Storage: Provider of automated sample management and storage systems, including ultra-low temperature and cryogenic storage solutions. Comparable to BioRep's hardware catalog (cryogenic containers, controlled-rate freezers, monitoring systems) and turnkey biobank design service.

Broad incumbents

• Azenta Life Sciences (formerly Brooks Life Sciences): Global biobanking, cryopreservation, and sample management services company (formerly Brooks Life Sciences / GENEWIZ). Directly comparable to BioRep's biobanking and cryopreservation core, but operating at much larger scale across multiple continents with broader life-sciences services.
• Eurofins Genomics: Part of Eurofins Scientific, offering genomic services, molecular biology, and NGS sequencing. Directly overlaps with BioRep's laboratory and NGS sequencing services, with much broader global scale and service catalog.
• Synlab (formerly Synlab Bondco): Europe's largest medical diagnostics services provider, with broad genetic and molecular biology testing capabilities including NIPT. Direct overlap with BioRep's laboratory services, NGS, and NIPT business, with much larger European footprint.
• Natera: US-based clinical genetic testing company with a leading NIPT (Panorama) and broader reproductive health franchise. Broad incumbent competing in the same NIPT category that BioRep's NATIVA brand addresses, though at very different scale and geographies.

Emerging players

• Genomic Vision: European molecular diagnostics and genomics company offering genetic testing and molecular combing services. Comparable to BioRep's molecular biology and NGS diagnostic offerings at a smaller, more specialized scale.
• Atlas Biomed: UK-based direct-to-consumer genetic and microbiome testing company. Both a partner (Atlas DNA and Microbiome tests distributed in Italy by BioRep) and an adjacent peer, sharing the consumer genetic test category with BioRep's NATIVA line.
• Inaphaea BioLabs (ValiRx): UK-based drug-screening and patient-derived cell services subsidiary of ValiRx, with a co-marketing agreement with BioRep. Emerging peer in the bio-digital CRO space, providing BioRep's European client network with high-throughput screening services in return for storage and logistics.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/channel/UCaBdm4S94lwzmV1-dh3d2GQ
• Facebookfacebook.com/BioRep.it
• LinkedInlinkedin.com/company/biorep

Compliance4 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about BioRep