Dirinco

What Dirinco does

Dirinco is a privately held medical device company founded in 1986 and headquartered in Oss, Netherlands, with operating subsidiaries in Belgium (Strombeek-Bever) and a commercial presence in France. The company specializes in hemodialysis and intensive care products, serving hospitals, dialysis centers, and ICU departments across the Benelux region. Its portfolio spans two therapeutic pillars: Intensive Care (CRRT machines such as the Nikkiso Aquarius, hemofiltration fluids including the proprietary CitraSol HF-CIT line, hemofilters, and anticoagulants) and Hemodialysis (Nikkiso DBB-EXA and NxStage System One S machines, dialyzers, dialysate solutions, and acid/bicarbonate concentrates). A third Access product line includes proprietary catheter lock solutions (Citra-Lock™ in vial and pre-filled syringe formats, registered as Class IIb medical devices), biocompatible catheters (Citra-XS, Joline), and disinfection accessories (Citra-Cap, Citra-Valve HF).

The proprietary technology stack is anchored in citrate-based anticoagulation — Dirinco markets multiple Citra-Lock™ concentrations (4%, 30%, 46.7%) designed to prevent clotting, biofilm formation, and heparin-induced thrombocytopenia, paired with CitraSol hemofiltration fluids for regional anticoagulation in CRRT. Distribution partnerships with Nikkiso (Aquarius, DBB-EXA) and NxStage/Fresenius Medical Care (System One S for home hemodialysis) extend the equipment range without in-house manufacturing of capital equipment. The Aquarius CRRT machine integrates citrate-calcium pumps and PDMS connectivity.

Dirinco's business model combines medical device and consumables sales (hardware and proprietary products), equipment rental for temporary capacity needs, and recurring service revenue from clinical training, 24/7 technical support, and maintenance contracts. The go-to-market is enterprise direct field sales to healthcare institutions in the Netherlands, Belgium, and France, supported by regional localized websites and a network of third-party distributors for the Citra-Lock™ international brand.

Name

Dirinco

Legal name

Dirinco BVBA

Website

https://dirinco.com

Company type

Private

Founded year

1986

Operating status

Operating

Headcount range

11–50 employees

Short description

Dirinco is a privately held Benelux medical device distributor founded in 1986, specializing in hemodialysis and CRRT products — including the proprietary Citra-Lock™ catheter lock line — plus Nikkiso and NxStage equipment, sold to hospitals and dialysis centers.

Ownership category

akta.pro rank

Product category

Renal Care Medical Devices

NAICS

Drugs and Druggists' Sundries Merchant Wholesalers (42421)

SIC

Wholesale-Medical, Dental & Hospital Equipment & Supplies (5047)

akta.pro industry

PRIMARYHLAHAKAF

Continuous Renal Replacement Therapy (CRRT) & Acute Dialysis Systems

Healthcare & Life Sciences/Medical Devices & Diagnostics/Renal & Dialysis Devices

SECONDARYHLAHAKAH

Renal Replacement Therapy Consumables (Bloodlines, Filters, Cartridges)

Healthcare & Life Sciences/Medical Devices & Diagnostics/Renal & Dialysis Devices

Keywords

• Hemodialysis equipment
• CRRT medical devices
• Catheter lock solutions
• Vascular access catheters
• Renal replacement therapy

Headquarters

HQ city

Oss

HQ country

Netherlands

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Personnel, Operations, Marketing or Sales, Technology or R&D, Infrastructure

Revenue model

1. Medical Device Sales: Dirinco generates revenue primarily through the sale of medical devices, equipment, and consumables for hemodialysis and intensive care, including CRRT machines, dialyzers, catheters, dialysate solutions, and access devices. The company distributes products from manufacturers like Nikkiso (Aquarius, DBB-EXA) and NxStage (System One S), as well as proprietary products like Citra-Lock™.
2. Equipment Rental: The company offers equipment rental services for temporary capacity problems, allowing customers to rent additional machines when needed.
3. Service and Support: Revenue generated from clinical support, technical support, and training services. Includes 24/7 customer service and technical support.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels3 records

Core offering

Dirinco distributes and supports medical devices and consumables for hemodialysis, continuous renal replacement therapy (CRRT), and vascular access, serving hospitals and dialysis centers in the Benelux region. Its portfolio combines proprietary citrate-based lock and hemofiltration solutions (Citra-Lock™, CitraSol) with distributed equipment from Nikkiso (Aquarius, DBB-EXA) and NxStage (System One S), complemented by 24/7 clinical, technical, and customer-service support and equipment-rental options.

Product overview

Dirinco is a patient-driven organization offering a comprehensive portfolio of medical devices and services for hemodialysis and intensive care, with over 30 years of experience in acute and chronic kidney failure treatment. The portfolio centers on two main therapeutic areas: Intensive Care (CRRT therapy with Aquarius machines, hemofiltration fluids including CitraSol products, Natriumcitraat anticoagulant, hemofilters, and plasma filters) and Hemodialysis (Nikkiso DBB-EXA and NxStage System One S dialysis machines, Smartflux and PMMA artificial kidneys, dialysate solutions including Dia-Lac and bicarbonate cartridges, acid concentrates, and transport containers). The Access product line includes Citra-Lock catheter lock solutions (vials and pre-filled syringes), Citra-XS and Joline catheters, Citra-Cap disinfection caps, and Citra-Valve HF connectors for infection prevention. Additional products include hemostasis devices (SureSeal bandages, FistulaStop, Fistula Clamp) and safety equipment (Redsense alarm). Dirinco provides comprehensive support services including clinical training, technical support (24/7), customer service, and equipment rental. Products are primarily distributed in the Netherlands, Belgium, and internationally through dedicated distributor networks.

Differentiator

Problem solved

Functional benefit

Brands

• Citra-Lock™: Citrate lock solution, anticoagulant and antimicrobial solution for catheters, registered as a medical device (Class IIb). Available in 4%, 30%, and 46.7% concentrations.
• Citra-Lock™S
• Citra-Gen®
• CitraSol HF-CIT-PRE™
• CitraSol HF-CIT-POST™
• Citra-XS™
• Citra-Valve HF™
• Citra-Cap
• Dia-LAC
• Aquamax

Products and services

• Aquarius CRRT / Aquarius+ Worldwide-applied continuous renal replacement therapy (CRRT) machine featuring all required treatment options, integrated citrate-calcium pumps, intelligent weighing balance to prevent unnecessary alarms, integrated plate heater for substitution fluid, battery backup, and PDMS connectivity, sold to hospital ICUs in the Benelux.
• Nikkiso DBB-EXA Compact, user-friendly, cost-effective hemodialysis machine with Dialysis Fully-Automated System (D-FAS), patient card integration, continuous dialysate dose measurement (DDM), blood pressure monitoring with UF reduction, and continuous dBV monitoring, sold to dialysis centers and hospitals.
• NxStage System One S Home hemodialysis system enabling high-frequency dialysis (5-6 times per week) with ready-to-use cassettes, PureFlow SL water purification option, and portable dialysate bags for travel use, sold to home dialysis programs and chronic kidney disease patients via prescribing centers.
• Citra-Lock Vials Citrate-based anticoagulant catheter lock solution (Class IIb medical device) in 4%, 30%, and 46.7% concentrations that prevents clotting, infections, and biofilm formation, improving catheter survival and flow for dialysis and central venous catheters.
• Citra-Lock S Pre-filled Syringes Pre-filled syringe version of the citrate catheter lock solution (Class IIb medical device) in Twin-Pack format (2x 2.5ml) for easier administration and improved safety, used in dialysis and central venous catheter care.
• CitraSol HF-CIT-PRE Citrate anticoagulation hemofiltration fluid for pre-dilution CVVH providing regional anticoagulation without affecting patient coagulation (RVG 113965), used in ICU CRRT.
• CitraSol HF-CIT-POST Citrate anticoagulation hemofiltration fluid for post-dilution CVVH providing regional anticoagulation without affecting patient coagulation (RVG 121335), used in ICU CRRT.
• Natriumcitraat 13% Sterile and pyrogen-free anticoagulant (CE 0373) for hemodialysis or CRRT, containing sodium citrate dihydrate 132.1g and citric acid monohydrate 10.36g per 1000ml.
• NaCl 0.9% Dirinco Sterile saline solution for priming extracorporeal blood line systems and as infusion fluid, available in PVC-free multi-layer polypropylene (250ml, 500ml, 1000ml, 2000ml).
• HF32BIC Bicarbonate-buffered hemofiltration fluid for CVVH and CVVHDF in both pre- and post-dilution, enabling faster recovery of acid-base balance than lactate-buffered fluids (RVG 19202).
• Dia-Lac Ready-to-use dialysate in 5L bags for use with NxStage System One, using L-lactate instead of bicarbonate for extended shelf life.
• Bicarbonate Cartridges Bicarbonate cartridges in powder form for all dialysis machines, available in 750g, 850g, and 1100g sizes (CE 0123).
• Citrodes Citric Acid 50% Citric acid 50% solution for dialysis applications, packaged in 10-liter cans.
• Acid Concentrates Acid concentrates for all dialysis machines including preset concentrate settings (1:45 ratio), available in 6L and 10L cans and transport containers (300L, 800L).
• Aquamax Hemofilters Hollow fiber hemofilters with 55,000 Dalton cut-off suitable for diffusive and convective therapies, available in HF 03 (0.30m2), HF 07 (0.70m2), HF 12 (1.20m2), and HF 19 (1.90m2) surface areas.
• Plasmafilters MPS Hollow fiber membranes in polyethersulfone (PES) for plasma filtration, available in MPS 03 (0.30m2), MPS 05 (0.45m2), and MPS 07 (0.68m2).
• Smartflux LFP/HFP Artificial Kidneys Low flux (LFP) and high flux (HFP) artificial kidneys with PUREMA membranes featuring reduced membrane thickness and homogeneous pore size for selective clearance of large molecules, used in hemodialysis.
• PMMA Artificial Kidneys Polymethylmethacrylate (PMMA) dialyzers with symmetric pore structure providing excellent beta-2-microglobulin clearance and plasma protein binding, suitable for patients with hypersensitivity to standard dialyzers.
• Citra-XS Catheters Biocompatible catheters without side holes developed based on clinical evidence, available in short-term and long-term (retrograde tunneling) versions for optimal blood flow, used in hemodialysis vascular access.
• Joline Long Term Catheters Tunneled catheters made of high-quality silicone with oval design to prevent kinking, featuring no side holes for improved blood flow, available in 27, 32, and 37cm lengths for long-term vascular access.
• Joline Short Term Catheters Double-lumen catheters made from ultra-thin thermosensitive polyurethane (D-line series) with no side holes and double-D design for excellent flow rates, used for short-term vascular access.
• Citra-Cap Disinfection Cap Disinfection cap for needleless connectors containing 70% alcohol sponge, providing continuous disinfection and replacing labor-intensive scrub procedures in dialysis applications.
• Citra-Valve HF Needle-free luer-lock connector for hemodialysis and central venous catheters that automatically closes after disconnection, reducing open hubs and microbial contamination.
• SureSeal Pressure Bandages Self-activating pressure dressings with cellulose sponge that swells on blood contact, reducing direct pressure time by 44%. Available in L and XL sizes (latex-free), used for dialysis access site hemostasis.
• FistulaStop Manual compression replacement device for post-dialysis hemostasis, providing comfortable, even pressure. Reusable with monthly replacement, suitable for shunts and transplants.
• Fistula Clamp Adjustable fistula clamp suitable for all arm sizes, made of durable plastic with stainless steel spring and aluminum hinge for comfortable and reliable compression at dialysis access sites.
• Redsense Venous needle detachment alarm system with accurate blood detection, automatic machine shutdown capability (IEC PAS63023 compliant), and cost-effective disposable sensor patches.
• Clinical Support Services Over 25 years of expert training and education for dialysis and hemofiltration equipment, provided on-site or at Dirinco training facilities in Oss, for hospitals and dialysis centers.
• Technical Support Services 24/7 technical support for malfunctions and repairs, standard maintenance, technical training, equipment modifications, and machine rental for temporary capacity issues, covering dialysis and CRRT equipment.
• Equipment Rental Services Equipment rental service that allows hospitals and dialysis centers to rent additional dialysis and CRRT machines for temporary capacity problems.

Quantifiable outcome

• Reduction in catheter-related infections through citrate-based lock solutions (Citra-Lock™)
• +2 more outcomes

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration1 record

Feature4 records

Partnerships

Four partnerships are on record, tiered core and minor.

• NikkisocoreChannel Partner/ Reseller/ DistributorDirinco distributes Nikkiso-manufactured medical equipment in the Benelux region. Products include the Aquarius CRRT machine (available in standard and Plus versions) and the DBB-EXA dialysis machine. The Nikkiso DBB-EXA is described as a compact, user-friendly, and cost-effective machine for safe and adequate hemodialysis.
• NxStage (Fresenius Medical Care)coreChannel Partner/ Reseller/ DistributorDirinco distributes the NxStage System One S for home hemodialysis in the Benelux market. The portable dialysis system enables frequent home dialysis (5-6 times per week) with an easy-to-use cassette system and optional PureFlow SL water purification unit.
• Citra-Gen®coreStrategic or Co-development PartnerCitra-Gen develops, produces, and sells innovative products for central venous access in hemodialysis, hematology, and oncology. Their products, including Citra-XS catheters, are distributed through Dirinco. The partnership aims to reduce catheter-related infections to zero based on advanced clinical guidelines and evidence.
• JolineminorChannel Partner/ Reseller/ DistributorDirinco distributes Joline catheters, including long-term tunneled catheters (oval design, silicone material) and short-term catheters (D-Line series, ultra-thin thermosensitive polyurethane). Both catheter types feature no side holes for improved flow and reduced thrombosis.

Scale indicators2 records

Recent moves6 records

Expansion highlights5 records

Emerging players

• Medivators (Cantel Medical): Provider of infection prevention products including catheter disinfecting caps and connectors. Comparable to Dirinco's Citra-Cap and Citra-Valve HF disinfection/connector lines sold into the same renal access channel.
• Outset Medical: US-listed manufacturer of the Tablo home/in-center hemodialysis system. Comparable as a direct competitor to the NxStage System One S in Dirinco's home hemodialysis portfolio, targeting the same shift-to-home care opportunity.
• Quanta Dialysis Technologies: UK-based developer of the SC+ portable hemodialysis system for hospital and home use. Comparable as a newer entrant competing with Dirinco's NxStage offering in the European home and portable dialysis segment.

Broad incumbents

• Fresenius Medical Care: World's largest integrated dialysis products and services company. Comparable because it offers the full stack of hemodialysis machines, CRRT, dialyzers, catheters and access consumables that overlap directly with Dirinco's portfolio, and owns NxStage — Dirinco's home dialysis partner.
• Nikkiso: Japanese manufacturer of Aquarius CRRT and DBB-EXA hemodialysis machines — both distributed by Dirinco. Comparable as the upstream OEM whose products Dirinco resells, and competes with Dirinco's service and consumables offering in the same accounts.
• Asahi Kasei Medical: Major dialyzer (artificial kidney) manufacturer supplying European dialysis providers. Comparable because Dirinco distributes competing dialyzer brands and competes for the same dialyzer slot in hospital formularies.
• B. Braun Avitum: Division of B. Braun providing hemodialysis machines (Dialog+), CRRT, dialyzers and dialysis fluids across Europe. Directly comparable as a device-plus-consumables dialysis specialist serving hospitals and outpatient centers in the same geographies as Dirinco.
• Baxter International (Vantive Kidney Care): Global medical device major with a dedicated kidney care franchise spanning HD/CRRT machines, dialyzers and access products. Directly competes with Dirinco's product portfolio across European hospitals and dialysis centers.
• Diaverum: One of Europe's largest independent renal care service providers operating dialysis clinics. Comparable because it is a large buyer of the same dialysis machines, consumables and access products that Dirinco distributes across Benelux-adjacent markets.

Regional players

• JMS Co. Japanese medical device company with a dialysis and infusion therapy portfolio. Comparable as a competing catheter and dialysis consumables supplier whose products can be found alongside or instead of Dirinco's Citra-XS and Joline catheter lines.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks7 records

Key highlights7 records

Customer concentration

• Xx.com/dirinco
• LinkedInlinkedin.com/company/dirinco

Compliance11 records

Revenue estimate

Valuation estimate

Number of profiles

Subsidiaries1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Dirinco