What Lake Immunogenics does

Lake Immunogenics, Inc. is a privately held biotechnology company founded in 1985 and headquartered in Ontario, New York, that manufactures polyclonal antibodies and plasma-derived biologics using a proprietary benchmark plasmapheresis process. Operating from a 155-acre farm with closed herds of horses, steer, llamas, and goats, the company collects plasma without compromising donor animal health and produces USDA-licensed therapeutic and reagent plasma products across equine (HiGamm, Pneumomune-Re, Normal Equine Plasma, Antigen Select line), bovine (BovaGamm), llama (CriaGamm), and goat (Caprimmune) categories, with frozen storage providing up to a 10-year shelf life. The company also produces over 35,000 liters of plasma under cGMP as raw material for human parenteral-use antibodies, reflecting simultaneous veterinary and pharmaceutical customer orientation.

The business operates across two complementary revenue streams: catalog sales of plasma-derived products distributed direct-to-customer via phone (800-648-9990) and a tiered e-commerce order portal (with separate pricing for veterinarians, non-veterinarians, and colleges/universities), and contract services including custom polyclonal antibody development, cGMP/non-GMP manufacturing, large animal preclinical studies (pharmacokinetic, implant, efficacy, antigen response), accredited long-term animal housing, and custom whole-blood products. Customers are concentrated in three vertical segments: veterinary schools and research institutions (the company claims 95% of US veterinary schools rely on its products), pharmaceutical and biotechnology firms requiring regulatory-compliant biologic manufacturing and custom antibodies, and licensed veterinarians and veterinary practices that purchase plasma therapeutics for conditions such as Failure of Passive Transfer and Rhodococcus equi pneumonia.

Revenue mechanics are unit-priced with separate pricing tiers, loyalty rewards applied at checkout, and next-day frozen shipping from a single domestic facility. The company maintains a substantial regulatory moat through USDA Facility, Research, and Biologics Licenses, CDC/APHIS Select Agent Registration, AAALAC International Accreditation, and a NYS Permit for Use of Living Animals, supported by a quality management system established in 2004 with comprehensive SOPs, change controls, deviation reporting, lot release, and in-house calibration. The competitive differentiator rests on the proprietary plasmapheresis platform (sustained 22 ml/kg collection indefinitely), four decades of institutional know-how, and embedded presence in veterinary curricula and reference textbooks.

Name

Lake Immunogenics

Legal name

Lake Immunogenics, Inc.

Website

https://lakeimmunogenics.com

Company type

Private

Founded year

1985

Operating status

Operating

Headcount range

11–50 employees

Short description

Lake Immunogenics is a privately held veterinary biologics manufacturer producing USDA-licensed polyclonal antibodies and plasma-derived products (equine, bovine, llama, goat) via proprietary plasmapheresis, serving veterinary schools, veterinarians, and pharmaceutical/biotech firms with therapeutic plasmas, custom antibody development, cGMP manufacturing, and preclinical animal study services.

Ownership category

akta.pro rank

Product category

Veterinary Biologics and Plasma-Derived Products

NAICS

Support Activities for Animal Production (1152)

SIC

Biological Products, (No Disgnostic Substances) (2836)

akta.pro primary industry

Biologics & Immunotherapies (Non-vaccine) (HLAMAEAK)

akta.pro secondary industries

Livestock & Production Animal Therapeutics (Rx) (HLAMAEAB), Veterinary Pharmacy, Vaccine & Biologics Services (AFAEANAK)

Keywords

• Polyclonal antibody production
• Plasma-derived biologics
• Veterinary therapeutics
• Animal blood products
• CGMP biologics manufacturing

Headquarters

HQ city

Ontario

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Operations, Technology or R&D, Supply Chain, Infrastructure, Marketing or Sales

Revenue model

1. Plasma-Derived Biologic Products: Sale of plasma-derived products for veterinary use including equine (HiGamm, Pneumomune-Re, Normal Equine Plasma, Antigen Select products), bovine (BovaGamm), llama (CriaGamm), and goat (Caprimmune) products. Products sold in various sizes (100ml to 1000ml) and shipped frozen.
2. Custom Antibody Development Services: Custom polyclonal antibody development services including protocol design, immunization programs, plasma collection, and efficacy studies. Partners with clients to develop antibodies for specific antigens using their donor animal herds.
3. cGMP Production Services: cGMP and non-GMP production services for biologic manufacturing. Offers lot release, quality assurance, validation protocols, and on-site GMP walk-in freezer storage.
4. Preclinical Animal Studies: Large animal preclinical study services including surgical training events, pharmacokinetic studies, implant testing, efficacy studies, and antigen response studies. Conducted in AAALAC-accredited facilities with standing IACUC.
5. Custom Animal Blood Products: Supply of whole blood from closed herds (equine, bovine, camelid, caprine) with standard anticoagulant (Na Citrate). Collected sterile and shipped overnight in coolers as a special request service.
6. Accredited Housing: Long-term study animal housing services with multiple housing options including pasture. Staff observes and documents daily well-being and care.

Pricing tiers

Go-to-market motion1 record

Distribution channels3 records

Marketing channels5 records

Core offering

Lake Immunogenics produces polyclonal antibodies and plasma-derived biologics using a proprietary plasmapheresis process on closed herds of horses, steer, llamas, and goats. The company manufactures USDA-licensed veterinary therapeutic plasma products (HiGamm, Pneumomune-Re, BovaGamm, CriaGamm, Caprimmune) and offers contract services including custom antibody development, cGMP production, preclinical animal studies, accredited animal housing, and custom whole blood products for veterinary medicine, pharmaceutical development, and biotech research.

Product overview

Lake Immunogenics is a biologics and plasma-derived products company offering a portfolio of animal health products and contract research services. The core product line consists of plasma-based biologics derived from closed herds of equine, bovine, llama, and goats, including USDA-licensed therapeutic products like HiGamm (equine IgG), Pneumomune-Re (Rhodococcus Equi Antibody), BovaGamm (bovine), Caprimmune (goat), and CriaGamm (llama). The Antigen Select product line includes plasma from immunized horses targeting specific pathogens (Rotavirus, Enteric antigens, Clostridium Perfringens, Botulism). The company complements its product offerings with contract services including custom polyclonal antibody development via plasmapheresis, cGMP production, preclinical animal studies, accredited animal housing, and custom whole blood products.

Differentiator

Problem solved

Functional benefit

Products and services

• HiGamm USDA LICENSED Equine plasma with IgG concentration ≥ 2800 mg/dl for intravenous treatment of Failure of Passive Transfer in equine neonates at 20ml/kg body weight. Available frozen in 1000ml and 500ml sizes.
• Pneumomune-Re (Rhodococcus Equi Antibody) USDA LICENSED USDA-licensed prophylactic treatment for prevention or reduction in severity of Rhodococcus equi foal pneumonia, with clinical results showing 58% reduction in incidence when foals receive two doses in the first month of life. Available frozen in 1000ml, 500ml bags, and 300ml bags made to order.
• Normal Equine Plasma Normal equine plasma for intravenous treatment of fluid and protein loss in equine neonates or adults. Available frozen in 1000ml.
• Antigen Select: Rotavirus Equine plasma collected from healthy horses recently immunized with Rotavirus and other equine diseases, used for replacement of fluids at veterinarian's discretion.
• Antigen Select: Enteric Select Equine plasma produced following immunization with J5 bacterin, LPS, Salmonella, Clostridium perfringens C and D, and Rotavirus. Available frozen in 1000ml bags for fluid replacement at veterinarian's discretion.
• Antigen Select: Clostridium Perfringens C, D, & Net F Equine plasma produced following immunization with Clostridium Perfringens strains C, D and Net F, used for replacement of fluids at veterinarian's discretion.
• Antigen Select: Botulism A, B, & C Toxins Equine plasma produced following immunization with Clostridium Botulinum A, B and C Toxins. Titer verification by Mouse Neutralization Assay (75-125 IU/ml). Demonstrated effectiveness in mouse model with 1500 LD50's challenge dose. Available in 500ml units.
• BovaGamm Bovine plasma from normal healthy steer with total IgG concentration ≥ 1800 mg/dl and total protein content ≥ 5 g/dl. Available frozen in 500ml and 1000ml sizes. Donors test negative for Bovine leukosis virus, Coxiella burnetti, Bluetongue, Johnes, Brucellosis, Glanders, and TB.
• Caprimmune Goat plasma for intravenous use in the caprine neonate or adult for fluid loss, plasma component loss, or plasma replacement. Contains antibodies from vaccination for normal caprine diseases. Available frozen in 100ml bags.
• CriaGamm Llama plasma for intravenous and intraperitoneal use in treating fluid and protein loss in the camelid neonate, and fluid replacement therapy in adult camelids. Ten year frozen shelf life. Average cria dose is 1 unit (275-330ml).
• Custom Antibody Development Custom polyclonal antibody development service using plasmapheresis technology, partnering with Ph.D. scientists and veterinarians to develop protocols meeting specific timelines and needs. Maintains closed herds of horses, steer, llamas and goats on site.
• Preclinical Animal Studies Large animal model studies including surgical correction/training events, pharmacokinetic studies, implant testing, efficacy studies, and antigen response studies conducted in AAALAC-accredited facilities. Partners with scientists and veterinarians to develop protocols meeting timelines and needs.
• cGMP Production Manufacturing capability under GMP or non-GMP protocols. Produced over 35,000 liters of plasma as raw material of antibodies for parenteral administration to humans under cGMP compliant project. Features independent QA department, change controls, deviation reporting, lot release, and on-site GMP-validated walk-in freezer space.
• Custom Animal Blood Products Supply of whole blood from closed herds (equine, bovine, camelid, caprine). Collected sterile using standard anticoagulant (Na Citrate) and shipped overnight in coolers. Special request service with custom volumes and delivery.
• Accredited Housing Long-term study animal housing in farm setting with multiple housing options including pasture. Staff observes and documents daily well-being and care. AAALAC-accredited facility.

Quantifiable outcome

• 58% reduction in the incidence of R. equi pneumonia when all foals were given two doses of Rhodococcus Equi Antibody (Pneumomune-Re) in the first month of life
• +3 more outcomes

Named customers3 records

Segments4 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Scale indicators6 records

Recent moves5 records

Expansion highlights4 records

Broad incumbents

• Virbac: Virbac is a global animal health company with a strong companion and livestock biologics portfolio, including specialty therapeutic products — comparable as a broad incumbent competing for the same veterinary end customers as Lake Immunogenics.
• Elanco Animal Health: Elanco Animal Health is a major animal health company with biologic, pharmaceutical, and vaccine products across species. Comparable as a broad incumbent whose portfolio could overlap with equine and livestock plasma therapeutics.
• Zoetis: Zoetis is the largest pure-play animal health company, offering vaccines, diagnostics, and therapeutics across livestock and companion animals. It is a broad incumbent that could expand into or replicate Lake Immunogenics' niche plasma biologics.
• Merck Animal Health: Merck Animal Health (a division of Merck & Co.) provides vaccines, anti-infectives, and parasiticides across species. Comparable as a broad incumbent with USDA-licensed biologics capabilities relevant to Lake Immunogenics' end markets.

Emerging players

• Large Animal Veterinary Associates (cGMP-adjacent CROs): Contract research organizations offering large animal preclinical and cGMP-adjacent services partially overlap Lake Immunogenics' preclinical studies and accredited housing business lines, often competing for the same biotech R&D budgets.

Others

• Bethyl Laboratories: Bethyl Laboratories is an antibody manufacturer producing goat and rabbit polyclonal antibodies for research use, comparable to Lake Immunogenics' custom antibody capability in technology and research end-market.
• ProSci Incorporated: ProSci specializes in custom polyclonal and monoclonal antibody production services for research and biotech customers, comparable to Lake Immunogenics' Custom Antibodies offering in customer type and project-driven service model.
• GenScript: GenScript provides custom antibody development and biologics services to researchers and biotech clients, comparable to Lake Immunogenics' Custom Antibodies service line in target customer and service model, though using recombinant rather than animal-derived polyclonal production.

Direct peers

• Colorado Serum Company: Colorado Serum Company is a USDA-licensed veterinary biologics producer serving livestock and equine markets with vaccines and antiserums — closely comparable to Lake Immunogenics' USDA-licensed biologic manufacturing model and customer base.
• Plasvacc USA: Plasvacc USA manufactures equine plasma products and other veterinary biologics, directly competing with Lake Immunogenics' HiGamm, Pneumomune-Re, and related equine plasma portfolio in the same veterinary segment.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/lake-immunogenics-inc

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Lake Immunogenics