What Bionnovation Biomedical does

Bionnovation Biomedical is a Brazilian medical device company headquartered in Bauru, São Paulo, that develops, manufactures, and distributes bone regeneration biomaterials, surgical membranes, fixation devices, and dental implants for dental and oral/maxillofacial surgery. The company's core offering centers on the Bonefill line of xenogenous bovine bone grafts (granulated, block, lamella, and cylindrical variants) and the Surgitime line of resorbable and non-resorbable membranes, complemented by synthetic bone substitutes (hydroxyapatite and beta-TCP), fixation screws, tent screws, tacks, surgical drills, bone collector drills, and graft kits. Products serve dental surgeons, oral surgeons, implantologists, and periodontists performing implant placement, alveolar ridge preservation, sinus lift, periodontal regeneration, and craniomaxillofacial reconstruction.

The company's Bonefill grafts are produced through a proprietary multi-phase purification process that solubilizes organic structures without thermal sintering, preserving the natural interconnected pore structure of bovine bone (Ca/P ratio ~1.67, porosity 65-80%, average pore size 100-600 μm). Bonefill carries a 5-year shelf life versus 2-3 years cited for competing products. Products are registered with Brazil's ANVISA (15+ product codes) and hold CE marking for European market access.

Bionnovation generates revenue through one-time sales of medical devices via an international network of authorized resellers across five continents, with quote-based pricing that is not publicly disclosed. The company supports commercialization through industry events (CIOSP, ROX, IN24, CIOSP25), clinical education programs, professional association partnerships, and multilingual content (Portuguese, English, Spanish). The company was founded in 1993 as Kunzel Brasil Equipamentos Odontológicos Ltda and was transformed and rebranded to Bionnovation Produtos Biomédicos S.A. following an April 2004 investment by US-based Aurora Ventures.

Name

Bionnovation Biomedical

Legal name

Bionnovation Biomedical LTDA

Website

https://bionnovation.com.br

Company type

Private

Founded year

1993

Operating status

Operating

Headcount range

101–250 employees

Short description

Bionnovation Biomedical is a Brazilian medical device company that manufactures and distributes bone regeneration biomaterials, membranes, fixation devices, and dental implants to dental and oral surgery professionals across five continents.

Ownership category

akta.pro rank

Product category

Dental Bone Regeneration Biomaterials

NAICS

Dental Equipment and Supplies Manufacturing (339114), Surgical Appliance and Supplies Manufacturing (339113)

SIC

Orthopedic, Prosthetic & Surgical Appliances & Supplies (3842), Dental Equipment & Supplies (3843), Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Bone Graft Substitutes & Orthobiologics (Synthetic/Allograft/DBM) (HLAHAEAG)

akta.pro secondary industry

Cartilage, Bone & Musculoskeletal Regeneration (HLAAAGAH)

Keywords

• Bone regeneration biomaterials
• Dental implant solutions
• Xenogeneic bone grafts
• Guided bone regeneration membranes
• Craniomaxillofacial surgical devices

Headquarters

HQ city

Salvador

HQ country

Brazil

HQ region

Latin America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Operations, Personnel, Technology or R&D, Supply Chain, Marketing or Sales

Revenue model

1. Biomaterials and Bone Graft Products: Sale of xenogeneic and synthetic bone graft materials for dental and maxillofacial regenerative procedures. Products include Bonefill granules, blocks, and lamina in various configurations.
2. Collagen Membranes: Sale of resorbable collagen membranes (Surgitime Collagen Pericardium) and non-resorbable barriers (Surgitime PTFE, Titanium) for guided bone regeneration.
3. Titanium Meshes and Fixation Devices: Sale of titanium meshes (Surgitime Titanium), screws, tent screws, and tacks for bone graft stabilization and fixation.
4. Surgical Instruments: Sale of surgical drilling instruments, bone collection drills, and graft kits for regenerative procedures.

Go-to-market motion3 records

Distribution channels3 records

Marketing channels10 records

Core offering

Bionnovation Biomedical manufactures and sells a comprehensive line of bone regeneration biomaterials and dental implant products. The portfolio includes xenogeneic bovine bone grafts (Bonefill line in granulated, block, lamellar and cylindrical forms), synthetic bone substitutes (Hydroxyapatite and Beta TCP), resorbable and non-resorbable membranes (Surgitime Collagen, PTFE, Titanium Mesh and Titanium Seal), fixation accessories (graft screws, tent screws, tacks), surgical instruments and grafting kits, and dental implants. Products are sold to dental surgeons, implantologists, periodontists, and oral/maxillofacial surgeons through an international distributor network.

Product overview

Bionnovation Biomedical is a Brazilian medical device company offering a comprehensive portfolio of bone regeneration and dental implant solutions. The product portfolio centers on the Bonefill line of xenogenous bovine bone grafts (available in granulated, block, lamella, and cylindrical forms) as the core product, complemented by synthetic bone substitutes (Hydroxyapatite and Beta TCP), surgical membranes (Surgitime Titanium Mesh, PTFE, Titanium Seal, and Collagen Pericardium), fixation accessories (graft screws, tent screws, and tacks), surgical instruments (cortical drills, bone collector drills, and grafting kits), and dental implants. The products are designed for oral and maxillofacial surgery, implant dentistry, and periodontics, providing solutions for bone grafting, guided bone regeneration, alveolar preservation, and dental rehabilitation.

Differentiator

Problem solved

Functional benefit

Brands

• Bonefill: Xenogeneic bovine bone graft substitute product line including granular, block, cylindrical, and laminar forms derived from bovine femur condyles. Contains Bonefill Denso, Bonefill Mix, and Bonefill Porous variants.
• Surgitime
• Surgitime Collagen
• Surgitime Titanium Seal

Products and services

• Bonefill Xenogeneic Bone Graft Line Xenogeneic bone graft substitute derived from bovine femur condyles, serving as an osteoconductive scaffold for bone regeneration in dental and maxillofacial surgery. Available in granulated (Denso, Mix, Porous with particle sizes 0.10-2.50mm), block (porous cancellous), cortical lamella (25.0 x 10.0mm, 0.9-1.40mm thickness), and cylindrical forms. Multi-phase purification preserves natural bone mineral structure with Ca/P ratio of 1.67, porosity 65-80%, pore size 100-600 μm, BET surface area ~77.5 m²/g, and 5-year shelf life.
• Hidroxiapatita (Hydroxyapatite) Synthetic calcium phosphate bone graft substitute for bone regeneration procedures in oral and maxillofacial surgery. Complements the xenogeneic Bonefill line for clinicians preferring synthetic materials.
• Beta TCP (Beta Tricalcium Phosphate) Synthetic beta-tricalcium phosphate bone graft material for bone regeneration and sinus lift procedures. Synthetic alternative for clinicians and indications where xenogeneic grafts are not preferred.
• Surgitime Titanium Mesh Non-resorbable titanium mesh for guided bone regeneration (GBR) procedures, providing structural support and space maintenance for bone grafts in vertical and horizontal ridge augmentation.
• Surgitime PTFE Membrane Non-resorbable polytetrafluoroethylene membrane for guided bone regeneration, acting as a barrier against soft tissue infiltration into bone graft sites.
• Surgitime Titanium Seal Non-resorbable titanium foil designed for intentional exposure in post-extraction alveolar sealing procedures. Made from commercially pure Grade 1 titanium (ASTM F67), thickness ~0.04mm, 100% waterproof, gamma sterilized. Protects surgical wounds against soft tissue invasion.
• Surgitime Collagen Pericardium Membrane Resorbable acellular bovine pericardium collagen membrane for guided bone regeneration. Natural purified Type I collagen with 19.52 μm average pore size, 3-year shelf life, gamma sterilized. Indicated for implant dentistry, periodontology, and oral and maxillofacial surgery.
• Parafusos de Enxerto (Graft Screws) Bone graft fixation screws available in Regular, Expanded, and Smart configurations with different macro-geometries for various surgical procedures and graft stabilization needs.
• Parafuso Tenda (Tent Screw) Tent screw designed to maintain space under a membrane during bone regeneration procedures, supporting the graft volume and shape.
• Tachinhas (Tacks) Tacks for membrane and graft fixation in bone regeneration procedures. Provides alternative fixation to screws for selected indications.
• Broca Corticale (Cortical Drill) Surgical drill for decorticalization of the recipient site. Made of surgical stainless steel (ASTM F899 440), 1.0mm diameter, available in 3 and 4mm depths, durability ~25 procedures.
• Broca Coletora Triple Blade (Autologous Bone Collector Drill) Triple-blade bone autogenous collector drill with DLC coating, available in 5.0mm and 7.0mm diameters for contra-angle handpiece, providing efficient autologous bone collection during regenerative procedures.
• Kit Enxerto (Bone Graft Surgical Kit) Bone graft surgical kit containing instruments required for bone grafting procedures, packaged as a single offering for clinicians.
• Kit Enxerto Premium Premium bone graft surgical kit with an enhanced instrument set for bone grafting procedures, targeted at surgeons requiring a more complete instrumentation solution.
• Implantes Dentários (Dental Implants) Dental implants offered as part of Bionnovation's portfolio for dental rehabilitation and tooth replacement, including Biomorse XP implants referenced in clinical case studies.

Quantifiable outcome

• Bone healing and integration in minimum 6 months
• +4 more outcomes

Named customers8 records

Segments4 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Partnerships

Five partnerships are on record, tiered minor.

• Por 1 Sorriso (1 Sorriso)minorStrategic or Co-development PartnerSocial impact partnership supporting dental health initiatives. Organization focused on promoting dental care access.
• CBCTBMF - Brazilian Association of Craniomaxillofacial SurgeryminorStrategic or Co-development PartnerProfessional association partnership with Brazilian association for craniomaxillofacial surgery, supporting the specialty through educational and professional development initiatives.
• SOBRAPE - Brazilian Association of PeriodontologyminorStrategic or Co-development PartnerPartnership with Brazilian periodontology association supporting professional education and research in periodontal regeneration.
• São Leopoldo MandicminorStrategic or Co-development PartnerPartnership with São Leopoldo Mandic dental research institution for academic collaboration, research support, and professional education in dental biomaterials.
• Eu ReciclominorOthersEnvironmental sustainability partnership with recycling organization, demonstrating company's commitment to environmental responsibility.

Scale indicators5 records

Recent moves9 records

Expansion highlights5 records

Direct peers

• Osteogenics Biomedical: US-based regenerative dental products company offering Cytoplast PTFE and collagen membranes, bone graft materials, and fixation hardware — a near-direct line-by-line competitor to Bionnovation's Surgitime membrane and fixation portfolio.
• NovaBone Products: US-based manufacturer specializing in synthetic bioactive bone graft substitutes (calcium phosphosilicate). Comparable in the bone graft substitute and synthetic biomaterial category that Bionnovation competes in with its Hydroxyapatite and Beta TCP lines.
• Botiss Biomaterials: German dental regeneration specialist offering bone grafts (cerabone, maxgraft), collagen membranes (Jason), and soft-tissue matrices. Highly comparable mid-sized European competitor with overlapping xenogeneic and allogeneic graft portfolio plus GBR membranes.
• ZimVie: US-listed dental and spine company with a Regenerative Solutions business ( RegenerOss bone grafts, CopiOs pericardium membrane). Direct comparable in dental bone graft substitutes and resorbable membranes with global distribution.
• Geistlich Pharma: Swiss global leader in dental bone regeneration (Bio-Oss xenograft, Bio-Gide collagen membrane). Most directly comparable to Bionnovation as the dominant incumbent in dental xenogeneic bone grafts that Bionnovation explicitly positions against on microporous structure.
• MIS Implants Technologies: Dental implant manufacturer (Dentsply Sirona group) with V3 and C1 implant systems and a growing regenerative portfolio. Comparable through combined implant-plus-biomaterial positioning for the same oral surgeon and periodontist customers.
• LifeNet Health: Non-profit tissue bank and biologics manufacturer offering allograft and xenograft dental bone grafts (Oracell, OraGraft) plus dental membranes. Comparable regenerative biomaterials portfolio serving the same oral surgery customer base.

Broad incumbents

• RTI Surgical: US-based surgical implant company with a meaningful dental and orthopedic bone graft business (Cortiva, BioAdapt) using both xenogeneic and synthetic materials. Comparable across the bone graft substitute and biologics category.
• Dentsply Sirona: Largest pure-play dental equipment and consumables manufacturer worldwide, including regenerative and implant lines. Broad incumbent whose dental biomaterials portfolio overlaps Bionnovation's regenerative offerings within a much wider product portfolio.
• Straumann: Global leader in dental implants that has expanded into biomaterials (XenoFlex, Membrane Plus) via Straumann Group. Comparable through overlapping regenerative offering plus implants, though at vastly larger scale and broader portfolio.

Market position

Strengths4 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/bionnovation
• YouTubeyoutube.com/@BionnovationBiomedical
• Facebookfacebook.com/bionnovationbiomedical
• LinkedInlinkedin.com/company/bionnovation-biomedical
• Instagraminstagram.com/bionnovation_biomedical

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Bionnovation Biomedical