Progeneron
Progeneron is a privately held California-based research company that develops and sells a single surgeon-developed topical hand cream for Palmar Fibromatosis and aging-hand conditions through its own e-commerce store, serving individual consumers in the US and Canada.
- Company typePrivate
- Founded2016
- HeadquartersAliso Viejo, United States
- Headcount11–50
- GTM typeB2C
- OfferingHardware or Manufacturing
What Progeneron does
Progeneron is a privately held research company headquartered in Aliso Viejo, California, that develops and manufactures natural and naturally derived topically applied products for hand and skin conditions. The company's only commercial product is Progeneron Hand Cream, a surgeon-developed daily-use formulation created by founder and Chief Medical Officer Dr. David Scharp, MD, to mitigate the progression and symptoms of Palmar Fibromatosis and to address general aging-hand issues including arthritis pain and reduced range of mobility. The formulation has been evaluated in a 180-day IRB safety study in which 95% of participants showed no signs of disease progression, forming the company's primary clinical evidence platform and differentiating claim.
The company's revenue model is a direct-to-consumer e-commerce operation built on a Shopify storefront at progeneron.net, with fulfillment delegated to Eresina, LLC and shipping handled via FedEx to the United States and Canada. Go-to-market combines consumer-facing content (website, blog, email newsletter) with a parallel physician channel via the Progeneron Physician Portal, where physicians can access clinical data and recommend the product to patients. Pricing is not publicly disclosed; one-time, pay-as-you-go purchase is the only commercial transaction type. The company reports no app, no API surface, no patents or trademarks, no disclosed funding rounds, and no institutional investors.
Progeneron operates as a founder-led micro-business (11-50 employees) with a single-SKU portfolio, a North-American geographic footprint, and no evident institutional capital or third-party scale signals in available sources. Business momentum is anchored almost entirely on the founder's credentials, the IRB study outcome, and a niche, condition-specific value proposition that targets aging-hand consumers and Palmar Fibromatosis patients — a small but underserved therapeutic niche where limited competing therapeutic options exist.
Progeneron firmographics
Firmographics- Name
- Progeneron
- Legal name
- Progeneron, LLC
- Website
- https://progeneron.net
- Company type
- Private
- Founded year
- 2016
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Progeneron is a privately held California-based research company that develops and sells a single surgeon-developed topical hand cream for Palmar Fibromatosis and aging-hand conditions through its own e-commerce store, serving individual consumers in the US and Canada.
- Ownership category
- akta.pro rank
Progeneron industry classification
Industry- Product category
- Topical Dermatological Skincare
- SIC
- Perfumes, Cosmetics & Other Toilet Preparations (2844)
- akta.pro primary industry
- Dermocosmetics & Medical-Grade Skincare (CRABAAAF)
Keywords
Where Progeneron is headquartered
LocationHeadquarters
- HQ city
- Aliso Viejo
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Progeneron business model
Business model- GTM type
- B2C
- Offering type
- Hardware or Manufacturing
- Cost components
- Supply Chain, Operations, Personnel, Marketing or Sales, Technology or R&D
Revenue model
- E-commerce Product Sales: Direct-to-consumer sales of Progeneron Hand Cream through their online store. One-time purchase model for topical hand cream products.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| One time/ perpetual license | Pay-as-you-go | Hand cream product pricing |
Go-to-market motion1 record
Distribution channels3 records
Marketing channels4 records
Progeneron product offering
Product offeringCore offering
Progeneron develops and manufactures Progeneron Hand Cream, a surgeon-developed daily-use topical cream formulated from natural and naturally derived ingredients to mitigate the progression of Palmar Fibromatosis, reduce arthritis pain, and improve range and mobility in aging hands. The product was the subject of a 180-day IRB safety study in which 95% of participants showed no signs of disease progression. Progeneron sells the cream direct-to-consumer through its Shopify-powered e-commerce site and supports physicians with clinical data via a dedicated Physician Portal.
Product overview
Progeneron offers a single core product — the Progeneron Hand Cream. This surgeon-developed daily-use hand cream is designed to mitigate symptoms associated with Palmar Fibromatosis and general aging hands, including arthritis pain and reduced mobility. The company was founded by Dr. David Scharp, MD, and operates as a research company focusing on natural and naturally derived topically applied products for hand and skin conditions. All products are developed and manufactured in the USA.
Differentiator
Problem solved
Functional benefit
Products and services
- Progeneron Hand Cream A surgeon-developed daily-use hand cream formulated to mitigate the progression and symptoms associated with Palmar Fibromatosis, reduce arthritis pain, and increase range and mobility in aging hands. Subject to a 180-day IRB safety study in which 95% of participants showed no signs of disease progression. Sold direct-to-consumer through the Progeneron website, with clinical data accessible to physicians through a dedicated Physician Portal.
Quantifiable outcome
- 95% of IRB study participants showed no signs of Palmar Fibromatosis disease progression over 180 days
- +1 more outcomes
Companies that use Progeneron
Customer profileSegments3 records
Ideal customer profiles3 records
Progeneron technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature1 record
Progeneron partnerships and signals
Strategic signalPartnerships
One partnership is on record.
- Eresina, LLCcoreEresina, LLC handles order fulfillment and shipping operations for Progeneron. All orders are processed by Eresina, LLC within 3 business days. They are responsible for customs, duties, and taxes processing and currently ship only to United States and Canada.
Scale indicators1 record
Recent moves6 records
Expansion highlights4 records
Progeneron competitors and assessment
Company assessmentDirect peers
- Biofreeze: Topical pain-relief brand (menthol-based) widely used by chiropractors, physical therapists, and consumers for arthritis and musculoskeletal pain. Comparable as a clinical-channel topical therapy sold through both professional recommendation and retail.
- Penetrex: Direct-to-consumer topical pain-relief brand targeting joint, muscle, and inflammation-related discomfort. Comparable DTC marketing approach and arthritis-pain value proposition to Progeneron Hand Cream.
- Blue-Emu: US-based topical pain-relief brand targeting arthritis, joint, and muscle pain with emu-oil-based formulations sold in drugstores and mass retail. Directly comparable as a topical therapy for arthritis and aging-hand symptoms in a similar price-and-channel band.
- Aspercreme: Sanofi-owned topical analgesic brand marketed specifically for arthritis and joint pain relief, including hand and wrist formulations. Closely comparable target indication (arthritic hand pain) and direct-to-consumer retail distribution model.
Broad incumbents
- Eucerin: Beiersdorf-owned medical skincare brand with a strong line of therapeutic hand creams and skin-condition products recommended by dermatologists. Directly comparable in the medical-grade hand-care category but with global distribution and a much broader portfolio.
- Neutrogena: Johnson & Johnson-owned skincare brand with hand and body care lines positioned at the medical-grade end of mass-market skincare. Comparable consumer-skincare category and brand authority, but with vastly greater distribution and product breadth.
- Gold Bond: Sanofi-owned therapeutic body and hand lotion brand widely distributed in US drugstores and supermarkets. Comparable target consumer (aging hands, daily moisturizing) at significantly larger retail scale and lower price points than Progeneron.
- CeraVe: L'Oréal-owned dermatology-focused skincare brand offering medical-grade cleansers, moisturizers, and therapeutic hand/body products. Comparable as a dermocosmetics positioning play, though at substantially larger scale and broader product range than Progeneron's single-SKU model.
- La Roche-Posay: L'Oréal-owned dermocosmetics brand specializing in physician-recommended skincare for sensitive and pathological skin conditions. Comparable medical-grade positioning and physician channel strategy, but at global scale and with a deep product portfolio.
Emerging players
- Theraworx: Topical recovery and cramp/muscle-relief brand sold through mass retail and DTC channels, with a science-backed clinical narrative. Comparable as a smaller emerging player using topical formulations for therapeutic indications with a similar go-to-market structure.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat3 records
Key risks6 records
Key highlights5 records
Customer concentration
Progeneron social profiles
Digital presenceProgeneron financial estimates
Financial estimateRevenue estimate
Valuation estimate
Progeneron leadership team
Management profileNumber of profiles
Profiles1 record
Progeneron funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Progeneron M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Progeneron
What does Progeneron do?
Progeneron develops and manufactures Progeneron Hand Cream, a surgeon-developed daily-use topical cream formulated from natural and naturally derived ingredients to mitigate the progression of Palmar Fibromatosis, reduce arthritis pain, and improve range and mobility in aging hands. The product was the subject of a 180-day IRB safety study in which 95% of participants showed no signs of disease progression. Progeneron sells the cream direct-to-consumer through its Shopify-powered e-commerce site and supports physicians with clinical data via a dedicated Physician Portal.
Is Progeneron a public or private company?
Progeneron is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was Progeneron founded?
Progeneron was founded in 2016. It employs 11 to 50 people.
Where is Progeneron based?
Progeneron is headquartered in Aliso Viejo, United States, in the North America region.
How does Progeneron make money?
One revenue line is on record: E-commerce Product Sales.
Who are Progeneron's main competitors?
Direct peers on record are Biofreeze, Penetrex, Blue-Emu and Aspercreme. Broad incumbents are Eucerin, Neutrogena, Gold Bond, CeraVe and La Roche-Posay. Theraworx is listed as an emerging player.
Does Progeneron have an API?
No public API is recorded for Progeneron.
What industry is Progeneron in?
Progeneron's product category is Topical Dermatological Skincare. Its primary akta.pro industry code is CRABAAAF, Dermocosmetics & Medical-Grade Skincare. Its SIC code is 2844.