Shanghai Rephile Bioscience
RephiLe Bioscience designs and manufactures laboratory water purification systems (5-600 L/h, Type I/II/CLRW/RO), Millipore-compatible replacement consumables, and laboratory filtration products, selling through direct sales and a distributor network to pharmaceutical, academic, clinical, and industrial laboratories in 100+ countries.
- Company typePrivate
- Founded2007
- HeadquartersMiami, United States
- Headcount—
- GTM typeB2B
- OfferingHardware or Manufacturing
What Shanghai Rephile Bioscience does
RephiLe Bioscience, Ltd. is a Shanghai-headquartered designer and manufacturer of laboratory water purification systems and laboratory filtration products, founded in 2007 and operating as a subsidiary of Duoning Biotechnology Group since 2022. Its core technology stack combines Continuous Electro-Deionization (CEDI/EDI), reverse osmosis, dual-wavelength UV (185/254 nm) with mercury-free LED variants, ion exchange, RFID-enabled consumables, and IoT touchscreen control to deliver Type I ultrapure (18.2 MΩ·cm, <2 ppb TOC), Type II EDI (5-16 MΩ·cm), CLRW-grade, and RO water at production rates from 5 L/h benchtop to 600 L/h centralized systems. The portfolio is organized into five system families (Genie, Large Genie, Super-Genie, NuZar, Direct Pure) plus a PURIST ultrapure line, a proprietary consumables catalog, and a parallel replacement-consumables business compatible with 15+ Millipore (Milli-Q, Elix, RiOs, AFS, Synergy, Direct-Q, Simplicity) platforms, accompanied by PCB/powerboard repair services. Laboratory filtration products under the RephiQuik (syringe filters, sterile, Max multi-layer composite), RephiDisc (membrane disc filters), and RephiTEKT (prefiltration) brands round out the offering.
RephiLe sells to a diversified global customer base across pharmaceutical QC/GMP plants, academic and government research institutes, hospital clinical laboratories, semiconductor and microelectronics manufacturers, environmental testing facilities, government certification agencies, and beverage QC labs; named customers include Harvard, MIT, Cornell, University of Pennsylvania, University of Washington, US FDA Labs, Merck & Co., GlaxoSmithKline, PerkinElmer, Amneal Pharma, and Molbio. The company executes a hybrid go-to-market combining direct regional sales (North America, Latin America, Europe, Asia/Africa/Oceania) with a long-tail distributor network reaching 100+ countries, including authorized partners Salus Bioscience, MIDSCI, Midland Scientific, and Bioland in the US, and country-specific distributors across Europe, Latin America, Asia, Africa, and Oceania.
Revenue is generated primarily through hardware sales of systems and proprietary replacement consumables, supplemented by recurring Millipore-compatible after-market consumables and PCB repair services. Pricing is quote-based rather than publicly disclosed, reflecting B2B customization and configuration variability. Manufacturing is supported by ISO 9001/14001/45001/50001-certified production facilities, and all products carry CE/UKCA marking and RoHS 3.0 compliance, with water quality meeting or exceeding ASTM, CLSI, CAP, and ISO Type I/II standards.
Shanghai Rephile Bioscience firmographics
Firmographics- Name
- Shanghai Rephile Bioscience
- Legal name
- RephiLe Bioscience Ltd.
- Website
- https://rephile.com
- Company type
- Private
- Founded year
- 2007
- Operating status
- Operating
- Short description
- RephiLe Bioscience designs and manufactures laboratory water purification systems (5-600 L/h, Type I/II/CLRW/RO), Millipore-compatible replacement consumables, and laboratory filtration products, selling through direct sales and a distributor network to pharmaceutical, academic, clinical, and industrial laboratories in 100+ countries.
- Ownership category
- akta.pro rank
Shanghai Rephile Bioscience industry classification
Industry- Product category
- Laboratory Water Purification Systems
- NAICS
- Pump and Compressor Manufacturing (33391)
- SIC
- Laboratory Apparatus & Furniture (3821)
- akta.pro primary industry
- Water & Wastewater Treatment Plant Equipment (Clarifiers, Aeration, Membrane Systems) (IMAHAEAJ)
Keywords
Where Shanghai Rephile Bioscience is headquartered
LocationHeadquarters
- HQ city
- Miami
- HQ country
- United States
- HQ region
- North America
Offices3 records
Markets served
Shanghai Rephile Bioscience business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Supply Chain, Operations, Technology or R&D, Personnel, Marketing or Sales, Infrastructure
Revenue model
- Lab Water Purification Systems: Sale of water purification systems including Genie, Large Genie, Super-Genie, NuZar, Direct Pure, and PURIST product lines ranging from benchtop to centralized high-output systems producing 5-600 L/h.
- Replacement Consumables: Replacement cartridges and accessories for RephiLe's own water systems and Millipore lab water systems. Includes AC Pack, P Pack, U Pack, T Pack, EDI modules, final filters, and tank accessories. RFID-enabled for tracking and monitoring.
- Filtration Products: Sale of laboratory filtration products including RephiQuik syringe filters (non-sterile, sterile, multi-layer composite), RephiDisc membrane filters, and RephiTEKT prefiltration systems.
- Repair Services: Repair services for PCBs and powerboards in water purification systems, offering maintenance support for existing customer installations.
Go-to-market motion3 records
Distribution channels6 records
Marketing channels7 records
Shanghai Rephile Bioscience product offering
Product offeringCore offering
RephiLe Bioscience designs and manufactures laboratory water purification systems producing Type I ultrapure, Type II pure, Clinical Laboratory Reagent Water (CLRW), and Type III RO water at 5 to 600 L/h. Its portfolio includes the Genie, Large Genie, Super-Genie, NuZar, Direct Pure, and PURIST product families, replacement consumables for Millipore water systems, and laboratory filtration products (RephiQuik syringe filters, RephiDisc membrane filters, RephiTEKT prefiltration). The company serves pharmaceutical, academic, clinical, and industrial laboratories in 100+ countries.
Product overview
RephiLe Bioscience is a specialized provider of laboratory water purification systems and laboratory filtration products. Its portfolio spans five product families: (1) Lab Water Purification Systems across four water grades — Type I Ultrapure (Genie A, Genie PURIST, Genie De-ion, NuZar U/U+/Q, Direct Pure U/U+/Q), Type II Pure/EDI (Genie E, Large Genie E, NuZar E/H, Direct Pure H, Super-Genie E), Clinical Laboratory Reagent Water/CLRW (Large Genie C, NuZar C/C-DI, Direct Pure C), and RO Water (Genie R, Large Genie R, NuZar R, Direct Pure R, Super-Genie R), available in benchtop (Genie), high-output benchtop (Large Genie), centralized stations (Super-Genie), compact (NuZar), and value (Direct Pure) form factors; (2) Replacement Consumables for Millipore Water Systems covering 15+ Millipore platform lines (Milli-Q Integral, Milli-Q Direct, Milli-Q Advantage A10, Elix, RiOs, AFS, Synergy, Direct-Q, Simplicity, Tanks, etc.) plus PCB/powerboard repair services; (3) Laboratory Filtration Products including RephiQuik syringe filters (non-sterile, sterile, Max composite), RephiDisc membrane filters (MCE, Nylon, PTFE, PES, PVDF), and 50 mm PTFE venting filters; and (4) RephiLe-proprietary consumables (cartridges, final filters, tanks) for its own water system platforms.
Differentiator
Problem solved
Functional benefit
Brands
- Genie: Line of laboratory water purification systems including Genie G, Genie U, Genie A, Genie E, Genie R, and PURIST variants.
- Large Genie
- Super-Genie
- NuZar
- Direct Pure
- PURIST
- RephiQuik
- RephiDisc
- RephiTEKT
Products and services
- Genie Series Lab Water Purification Systems Benchtop ultrapure and EDI lab water systems including Genie G (5/10/15 L/h Type I and Type II EDI from tap), Genie U (12/24/32 L/h RO and Type I), Genie PURIST (Type I from feed water), Genie A (Type I for ICP-MS, HPLC, LC-MS, molecular biology), Genie E (5/10/15 L/h Type II EDI), and Genie R (12/24/32 L/h Type III RO). Integrates IoT control, mercury-free UV LED lamps, RFID cartridges, and advanced EDI modules. Designed for research, analytical, and pharmaceutical laboratories.
- Large Genie Series High-Output Benchtop Water Systems High-output benchtop water systems producing up to 1,900 L/day of pure and ultrapure water. Includes Large Genie G 30/60 (Type I + Type II EDI), Large Genie U 40/80 (RO + Type I), Large Genie E 30/60 (Type II EDI), Large Genie C 40/80 (CLRW), and Large Genie R 40/80 (Type III RO). Designed for larger labs and pilot production facilities with a small benchtop footprint.
- Super-Genie Series Centralized Water Purification Stations
Quantifiable outcome
- EDI water resistivity >5 MΩ·cm (typically 10-16 MΩ·cm) at 25°C
- +4 more outcomes
Companies that use Shanghai Rephile Bioscience
Customer profileNamed customers18 records
Segments7 records
Ideal customer profiles5 records
Shanghai Rephile Bioscience technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature8 records
Shanghai Rephile Bioscience partnerships and signals
Strategic signalPartnerships
Four partnerships are on record, tiered core and regional.
- Duoning Biotechnology GroupcoreRephiLe Bioscience joined Duoning Biotechnology Group in 2022, gaining access to expanded resources, distribution network, and organizational support. The Duoning Group includes related entities like Duoning Japan (duoningbio.co.jp) and BioScience (thebiox.com).
- Duoning JapanregionalDuoning Japan operates as the regional partner for Japan, collaborating with RephiLe for local market presence. Also partners with PreFluid for joint exhibitions like JASIS 2025.
- Pramuk HealthcareregionalIndia partner Pramuk Healthcare actively participates in industry exhibitions including PharmaLytica-2022 and SMBT mega conferences, promoting RephiLe products in the Indian market.
- PreFluidregionalPreFluid collaborated with RephiLe and Duoning Japan for joint exhibition at JASIS 2025 in Japan, demonstrating marketing and exhibition partnership for regional market development.
Scale indicators6 records
Recent moves7 records
Expansion highlights4 records
Shanghai Rephile Bioscience competitors and assessment
Company assessmentBroad incumbents
- Avantor: Avantor distributes laboratory supplies including water purification systems and consumables globally. It competes with RephiLe through its distribution relationships with academic and pharma customers.
- Suez Water Technologies (Veolia): Veolia's water technology division includes ELGA LabWater and broader lab/industrial pure water offerings. It competes broadly with RephiLe across lab water purification and is also a parent of a direct competitor.
- Sartorius: Sartorius is a major bioprocessing and lab consumables supplier that overlaps with RephiLe in pharmaceutical QC and bioprocess applications, where customers bundle water purification with upstream/downstream bioprocess equipment.
- Evoqua Water Technologies (now part of Xylem): Evoqua (acquired by Xylem) provides water treatment solutions including laboratory and industrial pure water systems. It overlaps with RephiLe at the larger centralized water system end of the spectrum (Super-Genie tier).
- Thermo Fisher Scientific (Barnstead): Thermo Fisher sells Barnstead and Pacific RO/Type I water systems as part of its broader lab products portfolio. It is a broad incumbent competing with RephiLe especially in pharma QC and academic settings where Thermo bundles water with instruments.
Emerging players
- Labconco: Labconco manufactures laboratory equipment including water purification systems alongside fume hoods and freeze dryers. It is a smaller US-based peer competing in benchtop lab water segments.
- Human Corporation: Human Corporation is a South Korean manufacturer of laboratory and medical water purification systems (e.g., Easy RO, Human Power I/II). It is a smaller Asia-based specialist peer overlapping with RephiLe in mid-tier academic and clinical applications.
Direct peers
- Aqua Solutions: Aqua Solutions is a US-based specialist in laboratory water purification systems (Type I and Type II). It is a smaller direct competitor to RephiLe in the North American academic and clinical lab segments.
- Merck Millipore (Milli-Q): MilliporeSigma (Merck KGaA) is the dominant incumbent in laboratory water purification with its Milli-Q, Elix, and RiOs systems. It is RephiLe's primary direct competitor and also the platform whose installed base RephiLe targets with replacement consumables.
- ELGA LabWater: ELGA LabWater (Veolia) is a long-established specialist in laboratory water purification systems (PURELAB, MEDICA, CENTRA). It competes head-to-head with RephiLe across Type I/II clinical and research water systems globally.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat5 records
Key risks5 records
Key highlights6 records
Customer concentration
Shanghai Rephile Bioscience social profiles
Digital presenceShanghai Rephile Bioscience compliance and trust
Trust signalCompliance12 records
Shanghai Rephile Bioscience financial estimates
Financial estimateRevenue estimate
Valuation estimate
Shanghai Rephile Bioscience leadership team
Management profileNumber of profiles
Shanghai Rephile Bioscience funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Shanghai Rephile Bioscience M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Shanghai Rephile Bioscience
What does Shanghai Rephile Bioscience do?
RephiLe Bioscience designs and manufactures laboratory water purification systems producing Type I ultrapure, Type II pure, Clinical Laboratory Reagent Water (CLRW), and Type III RO water at 5 to 600 L/h. Its portfolio includes the Genie, Large Genie, Super-Genie, NuZar, Direct Pure, and PURIST product families, replacement consumables for Millipore water systems, and laboratory filtration products (RephiQuik syringe filters, RephiDisc membrane filters, RephiTEKT prefiltration). The company serves pharmaceutical, academic, clinical, and industrial laboratories in 100+ countries.
Is Shanghai Rephile Bioscience a public or private company?
Shanghai Rephile Bioscience is a private company. It is classified as corporate owned and is currently operating.
When was Shanghai Rephile Bioscience founded?
Shanghai Rephile Bioscience was founded in 2007.
Where is Shanghai Rephile Bioscience based?
Shanghai Rephile Bioscience is headquartered in Miami, United States, in the North America region.
How does Shanghai Rephile Bioscience make money?
Four revenue lines are on record. Lab Water Purification Systems are the primary driver. The others are replacement Consumables, filtration Products and repair Services.
Who are Shanghai Rephile Bioscience's main competitors?
Broad incumbents on record are Avantor, Suez Water Technologies (Veolia), Sartorius, Evoqua Water Technologies (now part of Xylem) and Thermo Fisher Scientific (Barnstead). Emerging players are Labconco and Human Corporation. Direct peers are Aqua Solutions, Merck Millipore (Milli-Q) and ELGA LabWater.
Does Shanghai Rephile Bioscience have an API?
No public API is recorded for Shanghai Rephile Bioscience.
What industry is Shanghai Rephile Bioscience in?
Shanghai Rephile Bioscience's product category is Laboratory Water Purification Systems. Its primary akta.pro industry code is IMAHAEAJ, Water & Wastewater Treatment Plant Equipment (Clarifiers, Aeration, Membrane Systems). Its NAICS code is 33391 and its SIC code is 3821.