What Biosigma does

Biosigma S.p.A. is an Italian privately held manufacturer of disposable plastic laboratory consumables and equipment, founded in 1988 and headquartered in Cona (Venice), Italy. The company operates from over 12,000 sqm of production facilities equipped with modern injection molding machines and integrated informatics, producing 20+ product categories spanning centrifuge tubes (DailySpin and HIGH SPEED lines, validated up to 20,000×g), cryogenic storage tubes (CryoGen® with 1D/2D coding for biobanking, validated to -196°C), rapid diagnostic tests, biological sample transport systems (UN3373/ADR compliant), specimen containers, hematology and histology supplies, cell culture products, PCR/molecular biology consumables, and specialty lines such as Drosophila research and gynecology/fertility products. The portfolio is anchored on two principal sub-brands — CLEARLine® for premium disposables and BIOBased® for sustainable bio-based materials — with dedicated systems including CLEARStable microbial preservation and BIODipper sterile sampling containers; an internal quality control laboratory applies molecular biology, biochemistry, and microbiology methodologies with batch sterility validated to SAL 10⁻⁶.

The company makes money through direct B2B enterprise sales of catalogued consumables on a quotation-based, pay-as-you-go pricing model, with an export department ([email protected], +39 0426 302226) handling international orders and downloadable catalogs. Go-to-market emphasizes enterprise field sales into research laboratories, clinical diagnostics facilities, and pharmaceutical industry customers across EMEA and select global markets, supplemented by participation in major industry trade shows (MEDICA Düsseldorf, Analytica Munich, MEDLAB Middle East, Life Sciences Baltics, Lab Supply Frankfurt) and digital channels including website, downloadable catalogues, LinkedIn, and YouTube. Distribution is primarily direct, with channel partnerships including Scientific Laboratory Supplies Ltd for the UK market and content-marketing alliances such as Biobanking.com. The company holds ISO 13485 and ISO 9001 certification, operates a Class 10,000 cleanroom for tissue-culture products, and maintains CE/IVD compliance under EU MDR for medical device and IVD product lines.

Key certifications (ISO 13485, ISO 9001, EU MDR/IVD, ADR/IMDG for dangerous goods transport, ISO 6579-1 for Salmonella, ISO 11731 for Legionella) and product-level performance validations (20,000×g centrifugation, -196°C cryostorage, SAL 10⁻⁶ sterility, DNase/RNase-free, metal-free) underwrite credibility in regulated procurement environments. The strategic posture evident in source data is one of moderate-growth portfolio diversification, sustainable-materials positioning, and selective geographic expansion through distributor partnerships, executed without disclosed external funding, M&A, or leadership changes.

Name

Biosigma

Legal name

Biosigma S.p.A.

Website

https://biosigma.com

Company type

Private

Founded year

1988

Operating status

Operating

Headcount range

101–250 employees

Short description

Biosigma S.p.A., founded in 1988 in Cona (Venice), Italy, manufactures and distributes disposable plastic laboratory consumables and equipment — including centrifuge tubes, cryogenic storage, rapid diagnostic tests, and specimen containers — to research, clinical diagnostics, and pharmaceutical laboratories worldwide, operating from over 12,000 sqm facilities under ISO 13485 certification and EU MDR/IVD compliance.

Ownership category

akta.pro rank

Product category

Laboratory Consumables

NAICS

Medical Equipment and Supplies Manufacturing (3391)

SIC

Plastics Products, Nec (3089), Laboratory Apparatus & Furniture (3821), Wholesale-Medical, Dental & Hospital Equipment & Supplies (5047)

akta.pro primary industry

Laboratory Consumables & Plasticware (Tips, Tubes, Plates, Filters) (HLAGAIAH)

akta.pro secondary industries

Diagnostic & Laboratory Packaging (Specimen Containers, Transport Tubes) (IMALAIAF), Single-Use Medical Disposables & Procedure Kits (Drapes, Tubing, Catheters, Syringes, Custom Packs) (HLAHANAG), Compostable & Bio-Based Packaging (PLA/PHA, Starch Blends, Cellulose Films) (IMALAMAB), Packaging, Labeling & Serialization Services (biologics/cold chain) (HLAAAKAJ)

Keywords

• Laboratory plastic consumables
• Biotechnology lab supplies
• Clinical diagnostics products
• Pharmaceutical labware
• Cryogenic storage tubes

Headquarters

HQ city

Cona

HQ country

Italy

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Operations, Supply Chain, Personnel, Technology or R&D, Infrastructure, Marketing or Sales

Revenue model

1. Laboratory Consumables Sales: Biosigma generates revenue through the manufacture and distribution of disposable plastic laboratory consumables and equipment for biotechnology, research, clinical chemistry, and pharmaceutical applications. Products include centrifuge tubes, cryogenic storage, rapid tests, specimen containers, and specialized diagnostic products sold via direct B2B channels to laboratories and healthcare facilities.

Pricing tiers

Go-to-market motion1 record

Distribution channels1 record

Marketing channels5 records

Core offering

Biosigma S.p.A. manufactures and globally distributes disposable plastic laboratory consumables for biotechnology, research, clinical chemistry, and pharmaceutical laboratories. Its catalog spans centrifuge tubes, cryogenic storage vials, rapid diagnostic test devices, specimen transport containers, multiwell culture plates, and histology/microbiology consumables. The company serves as a one-stop supplier to diagnostic, research, and pharmaceutical laboratory workflows through its BIOBased and CLEARLine sub-brands.

Product overview

Biosigma is an Italian biotechnology and clinical chemistry company (established 1988) specializing in the development, manufacturing, and distribution of disposable plastic laboratory consumables and equipment for research, biotechnology, clinical chemistry, and pharmaceutical laboratories. The product portfolio operates under two primary sub-brands: BIOBased® (sustainable bio-based materials) and CLEARLine® (premium quality laboratory disposables), supplemented by specialized product categories. Core products include cryogenic storage solutions (CryoGen® Tubes with 1D/2D coding for biobanking), centrifuge tubes (DailySpin and HIGH SPEED lines up to 20,000 xg), rapid diagnostic tests (pregnancy, oncology, infectious disease, drugs of abuse), biological sample transport systems (UN3373 compliant), specimen containers, hematology supplies, histology products, and cell culture plates. The company maintains over 12,000 sqm manufacturing facilities in Venice, Italy, with an internal laboratory for quality control supporting molecular biology, biochemistry, and microbiology testing protocols.

Differentiator

Problem solved

Functional benefit

Brands

• BIOBased®: Sustainable laboratory consumables product line made from bio-based materials, including BIOBased CryoGen tubes and microtubes.
• CLEARLine®
• CLEARStable
• BIODipper

Products and services

• BIOBased Bio-based Laboratory Consumables Sub-brand of disposable plastic lab consumables manufactured from bio-based polymers, designed for laboratories and institutions seeking sustainable alternatives to fossil-fuel-derived plastics without compromising sterility or assay performance.
• CLEARLine Certified Plastic Consumables Sub-brand of certified DNase/RNase-free, pyrogen-free, sterile plastic laboratory disposables for sensitive molecular biology, cell culture, and clinical chemistry applications.
• CryoGen Cryogenic Storage Tubes and Vials Product line of cryogenic vials and storage systems for ultra-low temperature preservation of biological samples, cells, and tissues in biobanks, biorepositories, and research laboratories.
• Centrifuge Tubes and Microcentrifuge Tubes Disposable polypropylene conical and round-bottom centrifuge and microcentrifuge tubes in graduated volumes for sample preparation in research and clinical workflows.
• Specimen Transport Containers (Transport Line) Leak-proof, sterile primary and secondary containers for the safe transport of biological specimens, blood, urine, and pathological samples between collection sites and diagnostic laboratories, meeting UN packaging requirements.
• Rapid Diagnostic Test Devices Lateral-flow and immunochromatographic rapid test cassettes and dipsticks for clinical, veterinary, food safety, and environmental screening applications.
• Multiwell Culture Plates and Cell Culture Vessels Tissue-culture-treated multiwell plates, flasks, and Petri dishes for in vitro cell culture and microbiology applications in research and pharmaceutical development.
• Hematology Products and E.S.R. Systems Manual erythrocyte sedimentation rate (ESR) systems and consumables for clinical hematology laboratories supporting routine blood analysis workflows.
• Histology and Microscopy Consumables Slides, coverslips, embedding cassettes, and microscopy accessories used in tissue processing and histological analysis workflows.
• PCR and Liquid Handling Consumables PCR tubes, plates, filter pipette tips, and reservoir liners for nucleic acid amplification and accurate liquid handling in molecular biology and diagnostic workflows.
• Gynecology and Fertility Consumables Disposable instruments and collection devices for gynecological sampling, fertility treatments, and assisted reproductive technology workflows.
• Filtration and Microbiology Products Membrane filters, filtration devices, culture media, and inoculation loops for microbiological analysis, water testing, and sterility testing.
• Urine Reading System and Urinalysis Consumables Automated urine strip readers and associated consumables for high-throughput urinalysis in clinical laboratories.

Quantifiable outcome

• Products validated for centrifugation up to 20,000×g ensuring performance in demanding molecular biology applications
• +1 more outcomes

Segments3 records

Ideal customer profiles1 record

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Four partnerships are on record, tiered core and minor.

• Scientific Laboratory Supplies Ltd (SLS)coreChannel Partner/ Reseller/ Distributor · 27 May 2024Scientific Laboratory Supplies Ltd is a UK-based distributor and event organizer. Biosigma participated in the SLS Show & Conference 2024, indicating an ongoing distribution partnership for the UK market.
• OgyreminorStrategic or Co-development PartnerOgyre is a sustainability initiative focused on waste recovery from oceans. Biosigma partnered with Ogyre achieving a milestone of 250 kg of waste recovered, demonstrating commitment to environmental sustainability.
• TreedomminorOthersTreedom is a tree-planting platform enabling companies to offset carbon emissions through reforestation projects. Biosigma displays the Treedom logo indicating partnership in environmental sustainability initiatives.
• Biobanking.comcoreGTM or Marketing PartnerBiobanking.com is a leading platform for biobanking content and education. Biosigma has multiple co-branded articles and features including coverage of the CLEARLine CryoGen range, positioning the company as an expert in cryogenic storage solutions.

Scale indicators3 records

Recent moves6 records

Expansion highlights4 records

Broad incumbents

• Thermo Fisher Scientific (Nunc / Nalgene): Global life-science leader whose Nunc, Nalgene, and Matrix brands cover essentially the entire range of laboratory consumables and cryogenic storage that Biosigma addresses, with vastly greater scale and distribution.
• Corning Life Sciences: US-based life-science major offering cell culture vessels, centrifuge tubes, cryogenic vials, and PCR plastics under Corning and Falcon brands; competes in the same product categories as Biosigma but at a much larger global scale.
• BD Biosciences (Falcon): BD's Falcon brand is a long-established supplier of cell culture flasks, centrifuge tubes, and microbiology consumables to research and clinical labs, competing directly with Biosigma's cell culture and tube product lines.
• Avantor / VWR: Global laboratory products distributor and manufacturer offering private-label and branded plastic consumables and chemicals to research and clinical labs; competes both as a direct seller and as a competing channel for Biosigma's catalog.

Direct peers

• Starlab International: German/European manufacturer of pipette tips, tubes, and lab plastics with strong focus on sustainability (e.g., bio-based tips) — a near-direct competitor to Biosigma's CLEARLine® portfolio and BIOBased® strategy.
• SARSTEDT: German family-owned manufacturer of sample collection tubes, blood collection systems, and laboratory disposables for clinical chemistry and life-science research — overlapping directly with Biosigma's specimen containers, hematology, and transport line.
• Greiner Bio-One: Austrian/German specialist in plastic laboratory consumables (tubes, plates, cell culture, biobanking) with a comparable European manufacturing heritage and product breadth across bioscience and clinical diagnostics — a very close functional analog to Biosigma.
• Eppendorf: German manufacturer of premium laboratory consumables including centrifuge tubes, microcentrifuge tubes, pipettes, and cryogenic storage — directly competing with Biosigma's CLEARLine® and CryoGen® lines in research and biotech labs.

Regional players

• LP Italiana: Italian laboratory consumables and diagnostics distributor/manufacturer with strong domestic and southern-European presence — comparable Italian footprint and complementary overlap with Biosigma's specimen container and clinical chemistry lines.

Emerging players

• Ratiolab: German specialty manufacturer of pipette tips, tubes, and PCR consumables focused on molecular biology — overlapping with Biosigma's PCR/plates and liquid handling lines at a smaller, niche scale.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/@biosigmas.p.a.206
• LinkedInlinkedin.com/company/biosigma
• Facebookfacebook.com/biosigma.srl

Compliance7 records

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Biosigma