1Day Sooner
1Day Sooner is a nonprofit advocacy organization that supports healthy volunteers participating in high-impact medical research, particularly human challenge trials. It serves academic research institutions, policy makers, and 40,000+ registered volunteers through recruitment, clinical trial support, and policy advocacy.
- Company typePrivate
- Founded2020
- HeadquartersClaymont, United States
- Headcount11–50
- GTM typeB2B and B2C
- OfferingServices
What 1Day Sooner does
1Day Sooner is a 501(c)(3) nonprofit advocacy organization founded in 2020 to represent healthy volunteers in infectious disease research, with a particular focus on human challenge studies where participants are deliberately infected with a pathogen under controlled conditions to accelerate vaccine and therapeutic development. Since founding, the organization has built a global community of more than 40,000 registered volunteers and provides services across three primary segments: healthy research volunteers seeking connection to high-impact trials, academic and nonprofit research institutions needing recruitment and participant-engagement support, and policy makers working on pandemic preparedness and clinical research ethics.
The organization's core offerings center on a Volunteer Hub for recruitment and engagement, a Challenge Study Compendium tracking human challenge studies from 2015 onward, a Target Product Profile design service for vaccine deployment, a Clinical Trial Abundance policy program, and — most recently — the Cooperative Participant Organization (CPO), launched in September 2025, which embeds 1Day Sooner staff scientists directly into study teams at partner institutions such as Leiden University, Malawi Liverpool Wellcome Research Programme, and the University of Oxford. Underlying technology is limited: 1Day Sooner does not develop proprietary software products, and its digital footprint consists of a content/website platform, social media channels, and event hosting rather than a software product suite.
1Day Sooner is funded entirely through donations and explicitly refuses contributions from commercial vaccine manufacturers to preserve advocacy independence. Its go-to-market is community-led: volunteers self-register through the website, partner institutions engage through the CPO and direct collaboration, and policy influence is exerted via white papers, open letters (including a 121-signatory Hepatitis C letter with five Nobel laureates published in The Lancet), and events such as the Clinical Trial Abundance Symposium and Operation Warp Speed 2.0 conference. The organization operates primarily from the United States but maintains regional chapters (1Day Africa, 1Day UK) and collaborates with institutions across Europe, North America, and Africa.
1Day Sooner firmographics
Firmographics- Name
- 1Day Sooner
- Legal name
- 1Day Sooner Inc.
- Website
- https://1daysooner.org
- Company type
- Private
- Founded year
- 2020
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- 1Day Sooner is a nonprofit advocacy organization that supports healthy volunteers participating in high-impact medical research, particularly human challenge trials. It serves academic research institutions, policy makers, and 40,000+ registered volunteers through recruitment, clinical trial support, and policy advocacy.
- Ownership category
- akta.pro rank
1Day Sooner industry classification
Industry- Product category
- Clinical Research Advocacy Services
- NAICS
- Voluntary Health Organizations (813212), Social Advocacy Organizations (8133)
- SIC
- Services-Commercial Physical & Biological Research (8731)
- akta.pro primary industry
- Global Health Research, Clinical Trials & Product Development Partnerships (PDPs) (HLAJAOAM)
- akta.pro secondary industries
- Public Health & Medical Volunteering Programs (EDAIAGAC), Community Health, Health Promotion & Behavior Change (SBCC) (BPADAIAL), Community Resilience, Preparedness Training & Exercises (HLAJAGAL)
Keywords
Where 1Day Sooner is headquartered
LocationHeadquarters
- HQ city
- Claymont
- HQ country
- United States
- HQ region
- North America
Offices2 records
Markets served
1Day Sooner business model
Business model- GTM type
- B2B and B2C
- Offering type
- Services
- Cost components
- Personnel, Operations, Marketing or Sales, Technology or R&D, Others
Revenue model
- Donations and Charitable Contributions: 1Day Sooner operates as a 501(c)(3) nonprofit organization and relies primarily on public donations. The organization explicitly states it does not accept money from organizations that could create a conflict of interest, such as commercial vaccine manufacturers, to maintain independence and advocacy integrity.
Go-to-market motion1 record
Distribution channels4 records
Marketing channels8 records
1Day Sooner product offering
Product offeringCore offering
1Day Sooner is a nonprofit advocacy organization that connects over 40,000 healthy volunteers worldwide with high-impact clinical trials, particularly human challenge studies where participants are deliberately infected with diseases in controlled conditions to accelerate vaccine and treatment development. The organization also operates the Cooperative Participant Organization (CPO), which embeds staff scientists directly into study teams at research institutions to provide participant engagement, recruitment, and operational support.
Product overview
1Day Sooner is a nonprofit advocacy organization operating a platform of interconnected programs to support and represent healthy volunteers in infectious disease research, particularly human challenge studies. The core offering consists of a Volunteer Hub that connects over 40,000 registered volunteers with clinical trials, complemented by the Cooperative Participant Organization (CPO) providing direct study support services to research institutions. Additional programs include the Clinical Trial Abundance initiative focused on FDA policy reform, a Challenge Study Compendium database, Target Product Profile design services, and a donations platform. The organization does not conduct trials itself but serves as an advocacy and support intermediary between volunteers and researchers.
Differentiator
Problem solved
Functional benefit
Quantifiable outcome
- Over 40,000 volunteers registered since 2020
- +2 more outcomes
Companies that use 1Day Sooner
Customer profileNamed customers5 records
Segments3 records
Ideal customer profiles3 records
1Day Sooner technology and API
TechnologyAPI detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
1Day Sooner partnerships and signals
Strategic signalPartnerships
13 partnerships are on record, tiered core and minor.
- Leiden UniversitycoreLeiden University is one of the first collaborators of 1Day Sooner's Cooperative Participant Organization (CPO) program. The university works with 1Day Sooner to conduct early-phase clinical trials driven by healthy participant involvement, particularly through controlled human infection model (CHIM) studies.
- Malawi Liverpool Wellcome Research ProgrammecoreMLW is a first collaborator of 1Day Sooner's CPO program and conducted the first CHIM trial ever in Malawi for pneumococcal vaccines. MLW has also launched the Participant Advocacy Group Initiative (PAGI) in collaboration with 1Day Sooner.
- University of OxfordcoreUniversity of Oxford is one of the first collaborators of 1Day Sooner's CPO program. Oxford has conducted multiple COVID-19 CHIM trials and malaria challenge trials through its Jenner Institute.
- UK Pandemic Ethics Acceleratorcore1Day Sooner partnered with the UK Pandemic Ethics Accelerator and sponsored 'The Ethics of Controlled Human Infection Model Studies for Mitigating Pandemic Risks' report, developed by the Oxford Uehiro Centre for Practical Ethics.
- Wellcome Trustcore1Day Sooner partnered with Wellcome Trust to host the PEARL (Pandemic Ethics Accelerator Report Launch) event at Wellcome Trust headquarters in London.
- The Lancet Gastroenterology & HepatologycorePublished the Hepatitis C Open Letter signed by 121 experts including 5 Nobel Prize winners in September 2023.
- Institute for ProgressminorCollaborated with Institute for Progress and Paul Mango on the Operation Warp Speed 2.0 conference in Washington, D.C.
- Federation of American ScientistsminorCollaborated with Federation of American Scientists on the Operation Warp Speed 2.0 conference and Day One project publications.
- Renaissance PhilanthropyminorPartnered with Renaissance Philanthropy on the Clinical Trials Abundance project, a partnership for policy research and advocacy.
- Center for Global DevelopmentminorCollaborated on the report 'Avoiding another lost decade to malaria vaccines' examining vaccine deployment challenges.
- Rethink PrioritiesminorCollaborated on 'Air Safety to Combat Global Catastrophic Biorisk' report exploring indoor air quality interventions.
- 1Day AfricacoreRegional chapter of 1Day Sooner focused on Africa, launched to extend the organization's reach and advocacy work on the African continent. Has launched campaigns to accelerate R21 malaria vaccine deployment.
- 1Day UKcoreRegional chapter of 1Day Sooner focused on the United Kingdom, with dedicated website at www.1daysooner.org.uk.
Scale indicators4 records
Recent moves7 records
Expansion highlights6 records
1Day Sooner competitors and assessment
Company assessmentBroad incumbents
- Drugs for Neglected Diseases initiative (DNDi): Established international nonprofit focused on developing treatments for neglected diseases through alternative R&D models including product development partnerships. DNDi overlaps with 1Day Sooner's clinical trial advocacy and PDP-adjacent work, though at a much larger operational scale.
- Global Health Advocacy Incubator (GHAI): Program of the Campaign for Tobacco-Free Kids supporting advocacy campaigns on global health priorities including pandemic preparedness, vaccines, and NCDs. GHAI shares 1Day Sooner's policy advocacy orientation and global health focus.
- Wellcome Trust: Major global charitable foundation funding biomedical research and pandemic preparedness. Wellcome is already a 1Day Sooner partner and represents a much larger incumbent in the same funding and advocacy ecosystem.
Others
- Waitlist Zero: Organ donation advocacy nonprofit also founded by Josh Morrison. Shares leadership and the patient/participant advocacy framework with 1Day Sooner, making it a thematic peer rather than a clinical trial competitor.
- Center for Global Development: Think tank producing research on global development policy including vaccine deployment and pandemic preparedness. 1Day Sooner has collaborated with CGD on reports, making it an adjacent policy and research partner rather than direct competitor.
- Federation of American Scientists (FAS): Science policy nonprofit advocating for evidence-based policy on issues including biosecurity and pandemic preparedness. FAS has collaborated with 1Day Sooner on the Day One project and Operation Warp Speed 2.0, making it a peer in the science-policy advocacy ecosystem.
Emerging players
- Clara Health: Clinical trial navigation and recruitment platform for patients. Shares 1Day Sooner's trial-access mission but targets patient populations seeking treatment rather than healthy volunteers for challenge studies.
- Antidote: Clinical trial recruitment platform that matches patients to trials using structured eligibility matching. Antidote overlaps with 1Day Sooner's volunteer-to-trial matching capability but focuses on patient populations rather than healthy volunteers for CHIM studies.
Direct peers
- Treatment Action Group (TAG): Independent activist and research organization working to accelerate treatment, vaccines, and cures for HIV, tuberculosis, and hepatitis C. TAG's policy advocacy and researcher engagement model parallels 1Day Sooner's approach to clinical trial modernization and disease-specific challenge study advocacy.
- AVAC: AIDS vaccine advocacy organization that builds advocacy coalitions, tracks HIV prevention research, and runs policy campaigns for accelerated vaccine and PrEP development. AVAC is the closest direct peer to 1Day Sooner's model of disease-specific research advocacy and volunteer/community mobilization.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks6 records
Key highlights7 records
Customer concentration
1Day Sooner social profiles
Digital presence1Day Sooner financial estimates
Financial estimateRevenue estimate
Valuation estimate
1Day Sooner leadership team
Management profileNumber of profiles
Profiles8 records
1Day Sooner funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
1Day Sooner M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about 1Day Sooner
What does 1Day Sooner do?
1Day Sooner is a nonprofit advocacy organization that connects over 40,000 healthy volunteers worldwide with high-impact clinical trials, particularly human challenge studies where participants are deliberately infected with diseases in controlled conditions to accelerate vaccine and treatment development. The organization also operates the Cooperative Participant Organization (CPO), which embeds staff scientists directly into study teams at research institutions to provide participant engagement, recruitment, and operational support.
Is 1Day Sooner a public or private company?
1Day Sooner is a private company. It is classified as nonprofit foundation owned and is currently operating.
When was 1Day Sooner founded?
1Day Sooner was founded in 2020. It employs 11 to 50 people.
Where is 1Day Sooner based?
1Day Sooner is headquartered in Claymont, United States, in the North America region.
How does 1Day Sooner make money?
One revenue line is on record: donations and Charitable Contributions.
Who are 1Day Sooner's main competitors?
Broad incumbents on record are Drugs for Neglected Diseases initiative (DNDi), Global Health Advocacy Incubator (GHAI) and Wellcome Trust. Others are Waitlist Zero, Center for Global Development and Federation of American Scientists (FAS). Emerging players are Clara Health and Antidote. Direct peers are Treatment Action Group (TAG) and AVAC.
Does 1Day Sooner have an API?
No public API is recorded for 1Day Sooner.
What industry is 1Day Sooner in?
1Day Sooner's product category is Clinical Research Advocacy Services. Its primary akta.pro industry code is HLAJAOAM, Global Health Research, Clinical Trials & Product Development Partnerships (PDPs), with a secondary code of EDAIAGAC, Public Health & Medical Volunteering Programs. Its NAICS code is 813212 and its SIC code is 8731.