1Day Sooner

What 1Day Sooner does

1Day Sooner is a 501(c)(3) nonprofit advocacy organization founded in 2020 to represent healthy volunteers in infectious disease research, with a particular focus on human challenge studies where participants are deliberately infected with a pathogen under controlled conditions to accelerate vaccine and therapeutic development. Since founding, the organization has built a global community of more than 40,000 registered volunteers and provides services across three primary segments: healthy research volunteers seeking connection to high-impact trials, academic and nonprofit research institutions needing recruitment and participant-engagement support, and policy makers working on pandemic preparedness and clinical research ethics.

The organization's core offerings center on a Volunteer Hub for recruitment and engagement, a Challenge Study Compendium tracking human challenge studies from 2015 onward, a Target Product Profile design service for vaccine deployment, a Clinical Trial Abundance policy program, and — most recently — the Cooperative Participant Organization (CPO), launched in September 2025, which embeds 1Day Sooner staff scientists directly into study teams at partner institutions such as Leiden University, Malawi Liverpool Wellcome Research Programme, and the University of Oxford. Underlying technology is limited: 1Day Sooner does not develop proprietary software products, and its digital footprint consists of a content/website platform, social media channels, and event hosting rather than a software product suite.

1Day Sooner is funded entirely through donations and explicitly refuses contributions from commercial vaccine manufacturers to preserve advocacy independence. Its go-to-market is community-led: volunteers self-register through the website, partner institutions engage through the CPO and direct collaboration, and policy influence is exerted via white papers, open letters (including a 121-signatory Hepatitis C letter with five Nobel laureates published in The Lancet), and events such as the Clinical Trial Abundance Symposium and Operation Warp Speed 2.0 conference. The organization operates primarily from the United States but maintains regional chapters (1Day Africa, 1Day UK) and collaborates with institutions across Europe, North America, and Africa.

Name

1Day Sooner

Legal name

1Day Sooner Inc.

Website

https://1daysooner.org

Company type

Private

Founded year

2020

Operating status

Operating

Headcount range

11–50 employees

Short description

1Day Sooner is a nonprofit advocacy organization that supports healthy volunteers participating in high-impact medical research, particularly human challenge trials. It serves academic research institutions, policy makers, and 40,000+ registered volunteers through recruitment, clinical trial support, and policy advocacy.

Ownership category

akta.pro rank

Product category

Clinical Research Advocacy Services

NAICS

Voluntary Health Organizations (813212), Social Advocacy Organizations (8133)

SIC

Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Global Health Research, Clinical Trials & Product Development Partnerships (PDPs) (HLAJAOAM)

akta.pro secondary industries

Public Health & Medical Volunteering Programs (EDAIAGAC), Community Health, Health Promotion & Behavior Change (SBCC) (BPADAIAL), Community Resilience, Preparedness Training & Exercises (HLAJAGAL)

Keywords

• Clinical trial advocacy
• Human challenge studies
• Volunteer recruitment services
• Infectious disease research
• Nonprofit health advocacy

Headquarters

HQ city

Claymont

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B and B2C

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Technology or R&D, Others

Revenue model

1. Donations and Charitable Contributions: 1Day Sooner operates as a 501(c)(3) nonprofit organization and relies primarily on public donations. The organization explicitly states it does not accept money from organizations that could create a conflict of interest, such as commercial vaccine manufacturers, to maintain independence and advocacy integrity.

Go-to-market motion1 record

Distribution channels4 records

Marketing channels8 records

Core offering

1Day Sooner is a nonprofit advocacy organization that connects over 40,000 healthy volunteers worldwide with high-impact clinical trials, particularly human challenge studies where participants are deliberately infected with diseases in controlled conditions to accelerate vaccine and treatment development. The organization also operates the Cooperative Participant Organization (CPO), which embeds staff scientists directly into study teams at research institutions to provide participant engagement, recruitment, and operational support.

Product overview

1Day Sooner is a nonprofit advocacy organization operating a platform of interconnected programs to support and represent healthy volunteers in infectious disease research, particularly human challenge studies. The core offering consists of a Volunteer Hub that connects over 40,000 registered volunteers with clinical trials, complemented by the Cooperative Participant Organization (CPO) providing direct study support services to research institutions. Additional programs include the Clinical Trial Abundance initiative focused on FDA policy reform, a Challenge Study Compendium database, Target Product Profile design services, and a donations platform. The organization does not conduct trials itself but serves as an advocacy and support intermediary between volunteers and researchers.

Differentiator

Problem solved

Functional benefit

Quantifiable outcome

• Over 40,000 volunteers registered since 2020
• +2 more outcomes

Named customers5 records

Segments3 records

Ideal customer profiles3 records

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Partnerships

13 partnerships are on record, tiered core and minor.

• Leiden UniversitycoreStrategic or Co-development Partner · 15 September 2025Leiden University is one of the first collaborators of 1Day Sooner's Cooperative Participant Organization (CPO) program. The university works with 1Day Sooner to conduct early-phase clinical trials driven by healthy participant involvement, particularly through controlled human infection model (CHIM) studies.
• Malawi Liverpool Wellcome Research ProgrammecoreStrategic or Co-development Partner · 15 September 2025MLW is a first collaborator of 1Day Sooner's CPO program and conducted the first CHIM trial ever in Malawi for pneumococcal vaccines. MLW has also launched the Participant Advocacy Group Initiative (PAGI) in collaboration with 1Day Sooner.
• University of OxfordcoreStrategic or Co-development Partner · 15 September 2025University of Oxford is one of the first collaborators of 1Day Sooner's CPO program. Oxford has conducted multiple COVID-19 CHIM trials and malaria challenge trials through its Jenner Institute.
• UK Pandemic Ethics AcceleratorcoreStrategic or Co-development Partner1Day Sooner partnered with the UK Pandemic Ethics Accelerator and sponsored 'The Ethics of Controlled Human Infection Model Studies for Mitigating Pandemic Risks' report, developed by the Oxford Uehiro Centre for Practical Ethics.
• Wellcome TrustcoreStrategic or Co-development Partner1Day Sooner partnered with Wellcome Trust to host the PEARL (Pandemic Ethics Accelerator Report Launch) event at Wellcome Trust headquarters in London.
• The Lancet Gastroenterology & HepatologycoreStrategic or Co-development PartnerPublished the Hepatitis C Open Letter signed by 121 experts including 5 Nobel Prize winners in September 2023.
• Institute for ProgressminorStrategic or Co-development PartnerCollaborated with Institute for Progress and Paul Mango on the Operation Warp Speed 2.0 conference in Washington, D.C.
• Federation of American ScientistsminorStrategic or Co-development PartnerCollaborated with Federation of American Scientists on the Operation Warp Speed 2.0 conference and Day One project publications.
• Renaissance PhilanthropyminorStrategic or Co-development PartnerPartnered with Renaissance Philanthropy on the Clinical Trials Abundance project, a partnership for policy research and advocacy.
• Center for Global DevelopmentminorStrategic or Co-development PartnerCollaborated on the report 'Avoiding another lost decade to malaria vaccines' examining vaccine deployment challenges.
• Rethink PrioritiesminorStrategic or Co-development PartnerCollaborated on 'Air Safety to Combat Global Catastrophic Biorisk' report exploring indoor air quality interventions.
• 1Day AfricacoreStrategic or Co-development PartnerRegional chapter of 1Day Sooner focused on Africa, launched to extend the organization's reach and advocacy work on the African continent. Has launched campaigns to accelerate R21 malaria vaccine deployment.
• 1Day UKcoreStrategic or Co-development PartnerRegional chapter of 1Day Sooner focused on the United Kingdom, with dedicated website at www.1daysooner.org.uk.

Scale indicators4 records

Recent moves7 records

Expansion highlights6 records

Broad incumbents

• Drugs for Neglected Diseases initiative (DNDi): Established international nonprofit focused on developing treatments for neglected diseases through alternative R&D models including product development partnerships. DNDi overlaps with 1Day Sooner's clinical trial advocacy and PDP-adjacent work, though at a much larger operational scale.
• Global Health Advocacy Incubator (GHAI): Program of the Campaign for Tobacco-Free Kids supporting advocacy campaigns on global health priorities including pandemic preparedness, vaccines, and NCDs. GHAI shares 1Day Sooner's policy advocacy orientation and global health focus.
• Wellcome Trust: Major global charitable foundation funding biomedical research and pandemic preparedness. Wellcome is already a 1Day Sooner partner and represents a much larger incumbent in the same funding and advocacy ecosystem.

Others

• Waitlist Zero: Organ donation advocacy nonprofit also founded by Josh Morrison. Shares leadership and the patient/participant advocacy framework with 1Day Sooner, making it a thematic peer rather than a clinical trial competitor.
• Center for Global Development: Think tank producing research on global development policy including vaccine deployment and pandemic preparedness. 1Day Sooner has collaborated with CGD on reports, making it an adjacent policy and research partner rather than direct competitor.
• Federation of American Scientists (FAS): Science policy nonprofit advocating for evidence-based policy on issues including biosecurity and pandemic preparedness. FAS has collaborated with 1Day Sooner on the Day One project and Operation Warp Speed 2.0, making it a peer in the science-policy advocacy ecosystem.

Emerging players

• Clara Health: Clinical trial navigation and recruitment platform for patients. Shares 1Day Sooner's trial-access mission but targets patient populations seeking treatment rather than healthy volunteers for challenge studies.
• Antidote: Clinical trial recruitment platform that matches patients to trials using structured eligibility matching. Antidote overlaps with 1Day Sooner's volunteer-to-trial matching capability but focuses on patient populations rather than healthy volunteers for CHIM studies.

Direct peers

• Treatment Action Group (TAG): Independent activist and research organization working to accelerate treatment, vaccines, and cures for HIV, tuberculosis, and hepatitis C. TAG's policy advocacy and researcher engagement model parallels 1Day Sooner's approach to clinical trial modernization and disease-specific challenge study advocacy.
• AVAC: AIDS vaccine advocacy organization that builds advocacy coalitions, tracks HIV prevention research, and runs policy campaigns for accelerated vaccine and PrEP development. AVAC is the closest direct peer to 1Day Sooner's model of disease-specific research advocacy and volunteer/community mobilization.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/1daysooner
• YouTubeyoutube.com/channel/UCSpAMpIt3xmcVAmMcR5y5DA
• Facebookfacebook.com/1daysooner
• LinkedInlinkedin.com/company/1daysooner
• Instagraminstagram.com/1daysooner

Revenue estimate

Valuation estimate

Number of profiles

Profiles8 records

Funding overview

Funding rounds

Investors

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M&A

Investments

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Frequently asked questions about 1Day Sooner