Medical Engineering Institute

What Medical Engineering Institute does

Medical Engineering Institute (株式会社医用工学研究所) is a Japanese healthcare data company founded in 2004 as a Mie University spinoff and headquartered in Tsu, Mie Prefecture. The company develops and operates CLISTA!, a medical data warehouse (DWH) that aggregates data from hospital electronic medical records, medical accounting systems, and departmental systems, deployed at 166 healthcare facilities in Japan including 43 university hospitals, 59 public hospitals, 29 quasi-public hospitals, and 35 private hospitals. Named customers include Asahikawa Medical University Hospital, Kurume University Hospital, National Hospital Organization Kyoto Medical Center, Toyohashi Municipal Hospital, Maebashi Red Cross Hospital, Keiyu Hospital, and Tokyo Saiseikai Central Hospital.

The product portfolio comprises three core lines: (1) CLISTA! and its modules (Search, Statistics, Push notifications, CLISTA!+) licensed to hospitals on subscription contracts with multi-year implementation cycles of approximately 6–9 months; (2) MEI RWD, a real-world data service providing anonymized/pseudonymized EMR-derived data from over 60 medical institutions covering approximately 6 million patient records as of June 2026 (targeting ~10 million by end of FY2026) to pharmaceutical and academic customers including Rohto Pharmaceutical and Takeda Pharmaceutical; and (3) Two-In (ツーイン), a patient-facing PHR mobile app launched in July 2025 and distributed through partner hospitals on a B2B2C basis. Revenue mix spans subscription licensing, data monetization, professional services, and a freemium patient app.

The company became a consolidated subsidiary of KDDI Corporation in April 2025 following an additional investment that increased registered capital from 90 million yen to 1,085 million yen. Through the KDDI partnership, MEI accesses the Osaka Sakai AI Data Center with NVIDIA GB200 NVL72 GPU infrastructure, sovereign cloud, ELYZA LLM technology, and ARISE analytics capabilities. The company holds ISO 27001 (ISMS) certification since 2015 and operates within Japan's APPI, GDPR, and CCPA compliance frameworks for medical data handling.

Name

Medical Engineering Institute

Legal name

株式会社医用工学研究所

Website

https://meiz.co.jp

Company type

Private

Founded year

2004

Operating status

Operating

Headcount range

51–100 employees

Short description

Medical Engineering Institute provides CLISTA! medical data warehouse systems, real-world data services, and the Two-In patient app to Japanese hospitals and pharmaceutical companies, with 166 facilities deployed and 6 million patient records as of June 2026.

Ownership category

akta.pro rank

Product category

Healthcare Data Analytics Software

NAICS

Custom Computer Programming Services (541511), Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services (518)

SIC

Services-Computer Programming, Data Processing, Etc. (7370), Services-Health Services (8000)

akta.pro industry

PRIMARYHLACAIAJ

Real-World Data (RWD) Platforms & Clinical Data Curation

Healthcare & Life Sciences/Digital Health & Health IT/Healthcare Data Platforms, Warehousing & Governance

SECONDARYHLACAIAI

FHIR/HL7 Data Repositories & Canonical Data Models

Healthcare & Life Sciences/Digital Health & Health IT/Healthcare Data Platforms, Warehousing & Governance

SECONDARYHLACAOAM

Real-World Data (RWD) / Real-World Evidence (RWE) & Observational Research Platforms

Healthcare & Life Sciences/Digital Health & Health IT/Clinical Trials & Research Informatics (eCOA/ePRO/EDC)

SECONDARYHLAGAJAF

Clinical & Translational Informatics (Clinical Data Integration/Real-World Data for R&D)

Healthcare & Life Sciences/Life Science Tools & Services (CRO/CDMO/Lab Services)/Life Science Software & Informatics (LIMS/ELN/Bioinformatics)

Keywords

• Medical data warehouse
• Real-world data services
• Hospital management analytics
• Electronic medical records integration
• Clinical pathway analysis

Headquarters

HQ city

Tsu

HQ country

Japan

HQ region

Asia

Offices5 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Infrastructure, Marketing or Sales, Operations

Revenue model

1. CLISTA! Medical DWH System: Licensing and deployment of the CLISTA! medical data warehouse system to hospitals. The company provides system installation, integration with hospital EMR and departmental systems, and ongoing support. Includes search, statistics, push notification, and CLISTA!+ modules.
2. Real-World Data (RWD) Services: Provision of anonymized/pseudonymized electronic medical record data to pharmaceutical companies and academic institutions for clinical research, drug development, market analysis, and evidence generation. Services include analysis reports, database provision, and research support.
3. ツーイン (Two-In) Patient App: Free PHR application for patients provided free of charge to users. Revenue model appears to be B2B, with hospitals (as medical institutions) deploying the service for their patients.
4. Hospital Management Consulting / Support Services: Professional services including hospital cost accounting system (HOMAS-Cloud), reporting outsourcing services, and implementation/coordinating services for medical data platform deployment.

Pricing tiers

Go-to-market motion1 record

Distribution channels4 records

Marketing channels7 records

Core offering

Medical Engineering Institute develops and sells the CLISTA! medical data warehouse (DWH) system that aggregates data from hospital electronic medical records, medical accounting, and departmental systems for search, statistical analysis, and alert notifications. It also provides MEI RWD (Real-World Data) services that supply anonymized/pseudonymized electronic medical record data to pharmaceutical companies and academic institutions, and operates the Two-In patient-facing mobile application (PHR) that connects patients with their medical institutions.

Product overview

Medical Engineering Institute offers a unified medical data platform portfolio comprising CLISTA! as the core healthcare DWH system, RWD (Real-World Data) services for pharmaceutical and research applications, and the ツーイン patient-facing mobile app. CLISTA! serves as the foundational hospital data warehouse with modular add-ons including search functionality, statistical analysis, push notifications, and CLISTA!+ for internal data sharing. The RWD service leverages the CLISTA! infrastructure to provide anonymized/pseudonymized medical data to pharmaceutical companies and academic researchers. The ツーイン app connects to hospital systems to deliver patient-facing services including appointment management and health record access.

Differentiator

Problem solved

Functional benefit

Brands

• CLISTA!: Medical data warehouse (DWH) system for hospitals that aggregates data from electronic medical records, medical accounting systems, and departmental systems for search, statistics, analysis, and alert notifications.
• ツーイン (Two-in)
• MEI RWD
• CLISTA!+
• CLISTA! Push Function

Products and services

• CLISTA! (クリスタ) Healthcare data warehouse (DWH) system that aggregates and integrates data from hospital electronic medical records, medical accounting systems, and various departmental systems (radiology, pathology, nursing, etc.). Enables cross-system search, statistical analysis, push-notification alerts, and data visualization for hospital management, clinical operations, medical safety, and research support. Installed at 166 facilities as of 2026 including 43 university hospitals, 59 public hospitals, 29 quasi-public hospitals, and 35 private hospitals.
• MEI RWD (Real-World Data Service) Real-World Data service providing anonymized/pseudonymized electronic medical record data and analysis services from over 60 partner medical institutions (80+ as of mid-2026) to pharmaceutical companies and academia for drug efficacy verification, post-marketing surveillance, clinical evidence generation, HEOR/HTA, medical affairs, and clinical research. Data covers examination results, prescriptions, procedures, and outcomes in chronological order, available approximately 1 month after clinical encounters.
• Two-In (ツーイン) Patient App Patient-facing mobile PHR application enabling patients to check appointments, view waiting numbers, receive notifications, access test results, record health metrics (blood pressure, blood glucose, weight, steps, sleep), and share information with family members and medical institutions. Provided free to end users; hospitals pay for deployment and integration.
• HOMAS-Cloud Hospital Cost Accounting System Hospital cost accounting system offered by Medical Engineering Institute as part of its hospital management support services, deployed alongside CLISTA! to enable cost-side analysis for hospital management.

Quantifiable outcome

• Alert notification unread period reduced from average 55 days to 2.86 days at Asahikawa Medical University Hospital
• +3 more outcomes

Named customers9 records

Segments4 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration4 records

Feature6 records

Partnerships

Nine partnerships are on record, tiered flagship, core and major.

• 武田薬品工業株式会社 (Takeda Pharmaceutical Company Limited)flagshipStrategic or Co-development Partner · 1 April 2026Joint project with KDDI and MEI using the KDDI Osaka Sakai AI Data Center to perform AI-powered multi-angle analysis of medical big data. Starting April 2026, the three companies will conduct exploratory projects for new patient value creation, with Takeda focusing on drug discovery and clinical research applications.
• 東京都済生会中央病院 (Tokyo Saiseikai Central Hospital)coreStrategic or Co-development Partner · 18 October 2025Collaborative clinical pathway analysis using CLISTA! since 2024. Two-phase program: Phase 1 (2024) — digitalization of pathway visualization; Phase 2 (2025) — scoring methodology for quantitative pathway quality assessment. Joint academic presentation at Japan Clinical Pathway Society.
• 戦略的イノベーション創造プログラム (SIP)majorOthers · 1 October 2025MEI data adopted for the SIP 'Integrated Healthcare System' program's generative AI utilization project, a national-level government initiative in Japan for healthcare innovation.
• NVIDIA CorporationcoreTechnology or Integration · 25 September 2025KDDI's AI Data Center uses NVIDIA GB200 NVL72 GPU infrastructure for medical big data processing. MEI leverages this infrastructure through KDDI partnership for AI-powered medical data analysis and medical-specialized LLM development.
• Google LLC (Google Cloud/Gemini)coreTechnology or Integration · 25 September 2025Collaboration through KDDI partnership for Google Cloud and Gemini AI technologies integrated into the medical vertical AI service architecture. Part of the 'medical vertical integrated AI service' concept combining medical big data, AI infrastructure, and generative AI.
• ELYZA Inc.majorTechnology or Integration · 25 September 2025ELYZA (KDDI group company) provides LLM technology for medical data analysis. Collaboration within KDDI group synergies to strengthen medical big data analytical capabilities through natural language processing and generative AI expertise.
• ARISE analytics (KDDI Group)majorTechnology or Integration · 25 September 2025KDDI group data science company with 350+ data scientists. Collaborates with MEI on advanced data analytics for medical applications. Part of KDDI group synergy strategy for medical data platform development.
• 前橋赤十字病院 (Maebashi Red Cross Hospital)flagshipStrategic or Co-development Partner · 10 July 2025First hospital to deploy Two-In patient app (July 2025). Joint project to improve patient experience and reduce staff workload. Hospital provides patient-facing deployment while MEI develops and operates the platform.
• ロート製薬株式会社 (Rohto Pharmaceutical Co., Ltd.)coreStrategic or Co-development Partner · 3 April 2025MEI provided real-world data analysis for Rohto's renal disease treatment research, helping visualize and analyze treatment realities. The analysis yielded valuable insights suggesting new drugs could address current treatment challenges, supporting Rohto's drug development pipeline.

Scale indicators7 records

Recent moves8 records

Expansion highlights6 records

Broad incumbents

• Oracle Health (formerly Cerner): Large-scale EHR and clinical data warehouse vendor. Provides similar hospital data aggregation and analytics capabilities as a much larger, internationally deployed incumbent, comparable to CLISTA! at enterprise scale.
• IQVIA Holdings: Global RWD/RWE and clinical research leader with broad pharma services portfolio. Operates significant Japan presence; competes with MEI RWD for pharma real-world evidence and observational research engagements.
• 3M Health Information Systems: Healthcare data and coding analytics vendor with hospital analytics and documentation products, comparable in addressing hospital-level data analytics and reporting for clinical and administrative use.
• Epic Systems: Dominant US EHR/clinical data platform. Comparable in providing aggregated hospital data infrastructure with research and analytics modules; broader scale but limited Japan footprint.
• Medidata Solutions (Dassault Systèmes): Clinical research data platform provider for pharma. Comparable as a pharma-research oriented data infrastructure vendor competing for similar sponsor budgets on the R&D side.

Direct peers

• M3 (m3.com): Japanese healthcare platform operating MR-kun, MD-Voice, and drug marketing data businesses overlapping with MEI's pharma RWD and physician engagement services; targets overlapping pharmaceutical and hospital customers.
• JMDC: Japan's leading RWD/healthcare data analytics company for pharma and academia. Provides claims data and EMR-derived datasets; competes head-to-head with MEI RWD for pharmaceutical R&D, HEOR, and academic research contracts.
• Flatiron Health: Roche-owned oncology-focused real-world evidence and EHR data platform. Highly comparable for hospital-derived EMR data monetization to pharma research customers, narrower therapeutic focus.
• TriNetX: Global real-world data network for clinical research and observational studies; comparable RWD-as-a-service model targeting pharma and academic users analogous to MEI RWD.

Regional players

• DeNA (Healthcare / MYCODE): Japanese internet conglomerate with healthcare and consumer health data businesses. Operates in the same Japanese market with overlapping patient-facing health information and data analytics themes.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights6 records

Customer concentration

• Facebookfacebook.com/clista.meiz

Compliance4 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles8 records

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Medical Engineering Institute