Hospital of the University of Pennsylvania

What Hospital of the University of Pennsylvania does

Penn Medicine is the clinical enterprise of the University of Pennsylvania, operating as a nonprofit academic medical center under The Trustees of the University of Pennsylvania. The system operates seven acute care hospitals across Pennsylvania and New Jersey — including Pennsylvania Hospital (founded 1751, the oldest hospital in the United States), the Hospital of the University of Pennsylvania, Penn Presbyterian Medical Center, Lancaster General Health, Princeton Health, and Doylestown Health — and is academically affiliated with the Perelman School of Medicine. Service lines span primary care, tertiary and quaternary specialty care (oncology, cardiology, neurology, gene therapy, transplant), pediatric care in partnership with the Children's Hospital of Philadelphia, and a Global Medicine international patient program.

The core technology platform is Epic Systems for electronic health records, with a unified myPennMedicine (MyChart) patient portal delivering scheduling, telehealth visits, imaging, and lab results across the system; the Doylestown Health integration scheduled for 2026 extends this footprint. The operating model is augmented by multiple hospital-at-home and SNF-at-home programs (PATH, Thrive, SNF at Home, Cavalry), an AI-powered chatbot on pennmedicine.org for consumer triage, and a Center for Health Justice with the Lift Every Voice community engagement platform. Research is a core function, evidenced by NIH-funded trials such as IGNITE (nearly $10M) and recognized outputs including the Breakthrough Prize (2026).

Revenue is generated as a nonprofit academic medical center through patient care services reimbursed by commercial insurers, Medicare, and Medicaid, supplemented by federal and philanthropic research funding (NIH and others) and investment income. The integrated delivery network — anchored by a unified EHR, home-based care programs, and an international patient channel — captures patient lifetime value across inpatient, ambulatory, post-acute, and home settings rather than relying on transactional single-visit revenue, while payer mix diversification across government and commercial payers reduces single-customer dependency.

Name

Hospital of the University of Pennsylvania

Legal name

The Trustees of the University of Pennsylvania

Website

https://pennmedicine.org

Company type

Private

Founded year

1751

Operating status

Operating

Headcount range

10,001+ employees

Short description

Penn Medicine is the nonprofit academic health system of the University of Pennsylvania, operating seven acute care hospitals across Pennsylvania and New Jersey with a unified Epic (MyChart) portal, hospital-at-home programs, and an international patient program.

Ownership category

akta.pro rank

Product category

Academic Medical Center Services

NAICS

General Medical and Surgical Hospitals (6221), General Medical and Surgical Hospitals (62211)

SIC

Services-General Medical & Surgical Hospitals, Nec (8062), Services-Hospitals (8060)

akta.pro industry

PRIMARYHLALABAC

Hospital-at-Home & Acute Virtual Care Platforms

Healthcare & Life Sciences/Telehealth Platforms/Provider-Integrated Virtual Care Platforms (Health Systems/Clinics)

SECONDARYHLALAAAA

Primary Care & General Medicine Virtual Care

Healthcare & Life Sciences/Telehealth Platforms/Direct-to-Consumer Virtual Care Platforms

SECONDARYHLADAFAL

Home-Based Chronic Disease Management (Skilled)

Healthcare & Life Sciences/Elder Care & Long-Term Care/Home Health Care Services (Skilled)

Keywords

• Acute care hospital
• Academic medical center
• Home health services
• Specialty care services
• Clinical research programs

Headquarters

HQ city

Philadelphia

HQ country

United States

HQ region

North America

Offices9 records

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Supply Chain, Technology or R&D, Infrastructure, Marketing or Sales

Revenue model

1. Healthcare Services Revenue: Acute care hospital services, outpatient clinics, specialty care, and diagnostic services billed to patients and payers including Medicare, Medicaid, commercial insurance, and self-pay. Revenue generated through facility charges, professional fees, and ancillary services.
2. Research and Grant Funding: Federal research funding from NIH and other agencies supporting clinical trials and translational research programs. Philanthropic donations through Penn Medicine Development for specific research initiatives and patient care programs.
3. Negotiated Insurance Contract Rates: Contracted rates with multiple insurance carriers including Aetna, Cigna, UnitedHealthcare, Highmark, Horizon, Independence Blue Cross, and many others. Rates negotiated per facility (Hospital of the University of Pennsylvania, Penn Presbyterian Medical Center, Pennsylvania Hospital, Chester County Hospital, Lancaster General Hospital, Princeton Medical Center).

Pricing tiers

Go-to-market motion1 record

Distribution channels6 records

Marketing channels7 records

Core offering

Penn Medicine operates an integrated academic health system delivering acute hospital care, specialty clinical services, outpatient care, home-based care, and clinical research through a network of hospitals across Pennsylvania and New Jersey. The system is affiliated with the Perelman School of Medicine and offers coordinated care across cancer, heart and vascular, neurology, orthopaedics, primary care, and women's health, with research and clinical trials integrated into patient care delivery.

Product overview

Penn Medicine operates as an integrated health system with a multi-platform digital portfolio. The core offering includes the Penn Medicine website and patient-facing platforms — primarily MyChart by myPennMedicine (Epic-based patient portal) for Penn Medicine, Chester County Hospital, Doylestown Health, and Princeton Medical Center patients, and MyLGHealth for Lancaster General Health patients. Beyond digital portals, Penn Medicine delivers care through hospital-at-home programs including PATH, Thrive, SNF at Home, and the Cavalry mobile care team, all integrated through a unified electronic health record. Research and community health initiatives include the Penn Medicine Center for Health Justice, Deeply Rooted community partnership, and the Lift Every Voice reporting platform. The system also offers an AI chatbot for interactive website features.

Differentiator

Problem solved

Functional benefit

Brands

• Penn Medicine at Home: Home healthcare services including palliative care, hospice, infusion therapy, and physical therapy
• MyChart by myPennMedicine
• Abramson Cancer Center
• Penn Cardiovascular Institute

Products and services

• Acute Care Hospital Services
• Specialty and Outpatient Care
• Penn Medicine at Home
• PATH (Practical Alternatives to Hospitalization)
• Thrive Program
• SNF at Home
• Penn Medicine Cavalry
• Abramson Cancer Center
• Penn Cardiovascular Institute
• Global Medicine Program
• Virtual Care and Telehealth
• Clinical Trials and Translational Research

Quantifiable outcome

• 30% reduction in breast cancer incidence linked to GLP-1 medications found in retrospective analysis of 110,000+ women
• +2 more outcomes

Named customers3 records

Segments4 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration5 records

AI capability2 records

Feature3 records

Partnerships

Six partnerships are on record, tiered core and minor.

• Children's Hospital of Philadelphia (CHOP)coreStrategic or Co-development PartnerCHOP is referenced as a partner for pediatric patient referrals and care coordination. CHOP handles pediatric specialty cases while Penn Medicine handles adult patients. The Penn Medicine Department of Pediatrics is based at CHOP, and the two institutions maintain collaborative relationships for research and patient care.
• Perelman School of MedicinecoreStrategic or Co-development PartnerThe Perelman School of Medicine at the University of Pennsylvania is the academic partner providing faculty, research programs, and medical education. Penn Medicine clinicians serve as faculty, enabling integration of research and clinical care.
• Lancaster Radiology AssociatesminorOthersThird-party radiology provider for Lancaster General Health locations. Patients are directed to contact for imaging estimates and services at Lancaster facilities.
• MRI GroupminorOthersThird-party MRI imaging provider serving Lancaster General Health locations. Separate billing and scheduling for MRI services.
• Lancaster Emergency AssociatesminorOthersEmergency medicine physician group providing services at Lancaster General Hospital. Separate billing from hospital facility charges.
• Deeply Rooted Community PartnerscoreStrategic or Co-development PartnerCommunity partnership initiative planting trees, greening vacant lots, and funding grassroots programs focused on health justice. Includes partnerships with community organizations in West Philadelphia neighborhoods, Men of 52K group, and local community members to address structural health inequities.

Scale indicators4 records

Recent moves6 records

Expansion highlights5 records

Broad incumbents

• Mayo Clinic: Elite nonprofit academic medical system with national/international referral base, research-driven care, and integrated multi-site hospital network at greater scale.
• Cleveland Clinic: Large nonprofit academic medical center with national/international footprint, extensive specialty care programs, and significant research output comparable to Penn Medicine.

Direct peers

• NewYork-Presbyterian Hospital: Columbia/Cornell-affiliated academic medical center operating a multi-campus hospital network with significant research output and complex specialty referral volumes in the Northeast.
• UCSF Health: UC-affiliated academic medical center on the West Coast with comparable research output, specialty care programs, and integrated hospital network.
• NYU Langone Health: Large academic medical center in the Northeast with integrated hospital network, research programs, and significant specialty care volumes that compete for similar patient and research markets.
• Stanford Health Care: Stanford University-affiliated academic medical center with research-driven specialty care, complex case mix, and integrated care delivery model.
• Mount Sinai Health System: NYC-based multi-hospital academic health system with research-intensive care delivery and integrated specialty services, comparable in size and structure to Penn Medicine.
• Johns Hopkins Medicine: Ivy League-affiliated academic medical center with integrated hospital network, research-intensive care delivery, and similar geographic reach in the Mid-Atlantic — directly comparable to Penn Medicine's positioning.
• Mass General Brigham: Harvard-affiliated integrated academic health system with multiple hospitals, unified EHR, and research-driven specialty care — a close analogue in scale, structure, and care delivery model.

Regional players

• Cedars-Sinai Medical Center: Major West Coast academic medical center with comparable research output and specialty care programs, serving a different primary geography than Penn Medicine.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks5 records

Key highlights6 records

Customer concentration

• YouTubeyoutube.com/playlist?list=PLRGEsZTjjo8mJFYrC_CsXoIgXzoYFBnxH
• LinkedInlinkedin.com/company/university-of-pennsylvania-health-system

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Subsidiaries7 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Hospital of the University of Pennsylvania