NADF

What NADF does

The National Adrenal Diseases Foundation (NADF) is a U.S.-based nonprofit 501(c)(3) organization (EIN #11-2777036) that educates, supports, and advocates for patients affected by adrenal diseases including Addison's disease, Cushing's syndrome, congenital adrenal hyperplasia, secondary adrenal insufficiency, pheochromocytoma, adrenoleukodystrophy, primary aldosteronism, and adrenal incidentaloma. Founded in 1994 (firmographics lists 1985; the 1994 date is corroborated by executive tenure records) and headquartered in Newton, USA, the organization operates with 1-10 staff and serves patients, caregivers, and healthcare professionals through a globally distributed model.

NADF delivers its mission through educational content (the 'All Things Adrenal' podcast, 'A Day in the Life' blog, video library, Q&A, and multi-language patient resources), clinical support tools (Pediatric Adrenal Insufficiency Action Plan with Pictograms co-developed with Walter Reed, Adrenal Crisis Emergency Resources including the 2025-updated Alert Flyer, Stress Dosing Guide, Hormone Replacement Protocol, Emergency Injection Kit instructions, and MedicAlert medical-ID resources), community services (peer support groups hosted on the Inspire platform, patient-recommended doctors directory), and research facilitation (MyAI Study, clinical trials information, and the historic 1997 North American Survey of Addison's Disease). The technology infrastructure is a Squarespace-hosted website serving as the primary digital hub; no proprietary software platform, mobile app, API, or AI capabilities are disclosed.

The organization is funded by tax-deductible individual donations and corporate sponsorships from ETON Pharma, Neurocrine Biosciences, and Recordati. All services are provided free of charge. Geographic reach extends internationally through NADF's participation in the International Adrenal Consortium (IAC), a network of 20 patient advocacy organizations across Europe, North and South America, and Australia, and through formal partnerships with NORD, Global Genes, the Endocrine Society, the International Society of Endocrinology, the Pediatric Endocrine Society, the American Association of Endocrine Surgeons, MedicAlert, and Inspire.

Name

NADF

Legal name

National Adrenal Diseases Foundation

Website

https://nadf.us

Company type

Private

Founded year

1994

Operating status

Operating

Headcount range

1–10 employees

Short description

NADF is a U.S. 501(c)(3) nonprofit that educates, supports, and advocates for patients with adrenal diseases through educational content, clinical tools, and peer support, with global reach via the International Adrenal Consortium.

Ownership category

akta.pro rank

Product category

Rare Disease Patient Advocacy

NAICS

Voluntary Health Organizations (813212), Individual and Family Services (6241)

SIC

Services-Educational Services (8200)

akta.pro primary industry

Adrenal Disorders (HLAKADAH)

akta.pro secondary industry

Disease-Specific Research & Support (e.g., Cancer, Diabetes, ALS) (BPAGACAA)

Keywords

• Patient advocacy services
• Adrenal disease education
• Rare disease support
• Patient education resources
• Healthcare professional resources

Headquarters

HQ city

Newton

HQ country

United States

HQ region

North America

Markets served

GTM type

B2B and B2C

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Technology or R&D

Revenue model

1. Donations: NADF operates as a 501(c)(3) nonprofit organization (ID #11-2777036) and relies on tax-deductible donations from individuals, memorial/tribute donations, and corporate sponsorships to fund education, support, and research programs.
2. Corporate Donations: Corporate donors including ETON Pharma, Neurocrine Biosciences, and Recordati provide financial support as part of the organization's funding model.

Go-to-market motion1 record

Distribution channels5 records

Marketing channels7 records

Core offering

NADF is a nonprofit patient advocacy organization that delivers free education, emergency preparedness resources, peer support, and research support to individuals affected by adrenal diseases (Addison's disease, Cushing's syndrome, CAH, secondary adrenal insufficiency, pheochromocytoma, ALD, primary aldosteronism, adrenal incidentaloma). It serves patients, caregivers, and healthcare professionals through educational content (podcast, blog, videos, downloadable guides), clinical tools (Adrenal Crisis Alert Flyer, Pediatric Action Plan with pictograms, hormone replacement protocols), community services (support groups, patient-recommended doctors directory), and awareness campaigns (Adrenal Disease Awareness Month).

Product overview

NADF (National Adrenal Diseases Foundation) is a nonprofit 501(c)(3) organization that operates as a patient advocacy and educational resource platform rather than a traditional technology product company. The organization provides a portfolio of patient education resources, clinical support tools, and community services focused on adrenal diseases including Addison's disease, Cushing's syndrome, congenital adrenal hyperplasia, and other adrenal disorders. The core offerings include educational content (podcasts, blogs, videos), clinical tools (Adrenal Crisis Emergency Resources, Pediatric Adrenal Insufficiency Action Plan with Pictograms, Hormone Replacement Protocols), patient resources (emergency kit instructions, medical ID recommendations), community services (support groups, doctor referrals), and research initiatives (MyAI Study, North American Survey). The organization does not operate a unified software platform but rather provides downloadable resources, links to external tools, and virtual programs including an annual conference.

Differentiator

Problem solved

Functional benefit

Products and services

• MyAI Study Research study initiative for individuals with adrenal diseases, providing an exclusive NADF channel for patient participation in clinical research.
• All Things Adrenal Podcast Educational podcast series covering topics related to adrenal diseases, adrenal insufficiency, and patient care.
• A Day in the Life Blog Blog featuring patient stories and perspectives about daily life experiences with adrenal disease.
• Pediatric Adrenal Insufficiency Action Plan with Pictograms Low-health-literacy pictographic action plan tool designed to help parents and clinicians take appropriate medical action for children with adrenal insufficiency. Developed in collaboration with Dr. Patrick Reeves at Walter Reed National Military Medical Center.
• Adrenal Crisis Emergency Resources Critical emergency intervention resources including the Adrenal Crisis Alert Flyer, Emergency Injection Technique instructions, Endocrine Society Guidelines, and StatPearl Adrenal Crisis reference materials.
• Adrenal Hormone Replacement Protocol and Quick Guide Downloadable protocol and quick guide for adrenal hormone replacement therapy for patients and healthcare providers.
• NADF Stress Dosing Guide Stress dosing guidelines document providing patients with instructions on adjusting medication during illness or stressful situations.
• Emergency Kit Instructions PDF instructions for assembling and using an emergency injection kit for adrenal crisis situations, including Solu-Cortef administration guidance.
• Medical Identification Resources Resources recommending MedicAlert jewelry and providing free emergency wallet cards with treatment instructions for emergency medical personnel.
• Support Groups Peer support group programs connecting patients and caregivers affected by adrenal diseases.
• Patient Recommended Doctors Directory Directory of healthcare providers recommended by NADF patients for adrenal disease care.
• Clinical Trials & Surveys Information Information about ongoing clinical trials and survey opportunities for adrenal disease research participation.
• North American Survey of Individuals with Addison's Disease (1997) First comprehensive survey of individuals with Addison's disease in North America, conducted in 1997 with 700 responses, providing statistical data on diagnosis, treatment, quality of life, and associated autoimmune conditions.
• Connecting the Dots in Adrenal Care Conference Annual virtual patient/provider roundtable conference featuring medical experts discussing adrenal disease topics, including emergency care and self-advocacy.
• Adrenal Disease Awareness Month (AADAM) Annual awareness month campaign (April) featuring educational activities, landmark light-up events, proclamations, and community engagement initiatives.

Segments3 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Partnerships

16 partnerships are on record, tiered core and minor.

• International Adrenal Consortium (IAC)coreStrategic or Co-development Partner · 7 April 2025NADF participates in the IAC, a global network of 20 patient advocacy organizations across Europe, North and South America, and Australia, dedicated to supporting individuals affected by adrenal diseases. The IAC launched International Adrenal Disease Awareness Day on April 7th.
• National Organization for Rare Disorders (NORD)coreStrategic or Co-development PartnerNADF is a member of NORD, the leading organization representing the rare disease community in the United States. This membership provides advocacy resources and collaborative opportunities for rare adrenal diseases.
• Global GenescoreStrategic or Co-development PartnerNADF participates in the Global Genes community of rare disease organizations, providing resources and support for patients with rare genetic adrenal conditions.
• American Association of Endocrine Surgeons (AAES)coreStrategic or Co-development PartnerCollaborative partnership for the annual International Adrenal Disease Awareness Day webinar 'Adrenal Awareness: Separating Myth from Fact' featuring medical experts from AAES including Dr. Priya Dedhia, Dr. Lauren Fishbein, Dr. Matt Nehs, and Dr. Anatoliy Rudin.
• Walter Reed National Military Medical CentercoreStrategic or Co-development PartnerPartnership with Dr. Patrick Reeves at Walter Reed to develop the Pediatric Adrenal Insufficiency Action Plan with pictograms - a low-health-literacy tool to improve parents' and clinicians' ability to comprehend and act on pediatric adrenal insufficiency protocols. Video instructions produced for patients and clinicians.
• Endocrine SocietycoreStrategic or Co-development PartnerLeading professional organization that formally recognizes April 7th as International Adrenal Disease Awareness Day, advancing accurate diagnosis and treatment innovation.
• International Society of EndocrinologycoreStrategic or Co-development PartnerGlobal professional organization recognizing International Adrenal Disease Awareness Day and supporting adrenal disease education initiatives.
• Pediatric Endocrine SocietycoreStrategic or Co-development PartnerProfessional society supporting pediatric adrenal disease awareness and education efforts through recognition of International Adrenal Disease Awareness Day.
• American Society of Endocrine SurgeonscoreStrategic or Co-development PartnerProfessional surgical organization collaborating with NADF on the 'Adrenal Awareness: Separating Myth from Fact' webinar for the 2026 International Adrenal Disease Awareness Day.
• A5 – the American, Asia, and Australia Alliance of ResearcherscoreStrategic or Co-development PartnerInternational research alliance recognizing International Adrenal Disease Awareness Day and contributing to global adrenal disease research efforts.
• Spanish Society of Endocrinology and Nutrition (SEEN)coreStrategic or Co-development PartnerSpanish professional endocrinology society recognizing and supporting International Adrenal Disease Awareness Day initiatives.
• Spanish Federation for Rare Diseases (FEDER)coreStrategic or Co-development PartnerSpanish rare disease federation supporting adrenal disease awareness and patient advocacy efforts.
• Official College of Physicians of Málaga (COMMALAGA)coreStrategic or Co-development PartnerSpanish medical professional organization recognizing International Adrenal Disease Awareness Day.
• MedicAlert FoundationcoreStrategic or Co-development PartnerMedicAlert provides emergency medical identification services recommended by NADF for all patients with adrenal insufficiency. The partnership promotes medical ID bracelets that alert emergency responders to patients' condition and need for stress dose corticosteroids.
• InspirecoreStrategic or Co-development PartnerNADF hosts its patient community group on the Inspire platform, connecting patients and caregivers for peer support and shared experiences.
• Hospital Italiano de Buenos AiresminorStrategic or Co-development PartnerHospital organizing monthly adrenal insufficiency workshops in Spanish starting April 10, supporting awareness month activities.

Scale indicators5 records

Recent moves6 records

Expansion highlights5 records

Others

• Endocrine Society: Leading global professional organization for endocrinology research and practice. Comparable as the premier professional society recognizing NADF's International Adrenal Disease Awareness Day and a key partner for clinical content and physician-facing resources.
• MedicAlert Foundation: Nonprofit providing emergency medical identification (bracelets, necklaces) recommended by NADF for all adrenal insufficiency patients. Comparable as a fellow nonprofit operating in the adrenal crisis emergency preparedness ecosystem where NADF directs patients for medical IDs.
• Inspire: Online patient community platform hosting NADF's National Adrenal Diseases Foundation patient community group. Comparable as the underlying community infrastructure provider that enables NADF's peer support group experience.
• American Association of Endocrine Surgeons (AAES): US professional society of endocrine surgeons that co-hosts NADF's annual awareness webinar. Comparable as a clinician-side counterpart that NADF partners with for surgical-adrenal content and physician referral channels.

Direct peers

• Cushing's Support & Research Foundation: Patient advocacy nonprofit dedicated specifically to Cushing's syndrome, one of the adrenal diseases NADF also covers. Directly comparable as a US disease-specific adrenal patient advocacy organization serving an overlapping patient population with similar educational and support offerings.
• Adrenal Insufficiency United: Patient advocacy organization focused on adrenal insufficiency. Directly comparable to NADF as an adrenal-specific patient advocacy nonprofit providing education, support groups, and emergency resources for the same core patient community.
• Pheo Para Alliance: Patient advocacy nonprofit focused on pheochromocytoma and paraganglioma, both adrenal tumors covered by NADF's disease library. Comparable as a fellow adrenal-condition-specific patient advocacy organization serving an overlapping rare disease patient population.

Broad incumbents

• Global Genes: US-based rare disease advocacy nonprofit with a global community of rare disease organizations, of which NADF is a participant. Comparable as a fellow disease-agnostic rare disease platform that NADF engages with for advocacy resources and collaborative programming.
• National Organization for Rare Disorders (NORD): Umbrella US nonprofit for the rare disease community; NADF is a NORD member organization. Comparable as a higher-tier rare disease advocacy body that NADF operates within, with overlapping member, donor, and advocacy ecosystems.

Emerging players

• The MAGIC Foundation: US nonprofit supporting families affected by various endocrine-related conditions including adrenal and growth disorders. Comparable as a fellow endocrine-focused patient advocacy nonprofit with overlapping educational resource and family support missions.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/NADF_Adrenal
• LinkedInlinkedin.com/company/national-adrenal-diseases-foundation

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about NADF