EndoSim

What EndoSim does

EndoSim LLC, founded in 2010 by Kai Matthes and headquartered in Bolton, Massachusetts, develops evidence-based simulation models for endoscopists and other healthcare professionals. The company's core technology is a hybrid simulation platform that combines reusable plastic and rubber hardware trainers (chiefly the proprietary EASIE-R series) with disposable ex-vivo animal tissue specimens sourced from USDA-inspected meat production facilities. This two-component model provides realistic haptic feedback for procedures including EGD, colonoscopy, ERCP, EUS, ESD, EMR, POEM, and laparoscopic, urologic, gynecologic, pulmonary, spine, and anesthesiology interventions, validated through 60+ peer-reviewed publications spanning 20+ years of research originating at Friedrich-Alexander-University of Erlangen.

The company monetizes through three distinct streams: (1) one-time hardware sales of simulators priced $1,475-$12,995 plus weekly rentals of $250-$475, (2) recurring consumable specimen sales at $85-$455 per unit, and (3) professional services including the GI Fellowship Training Program ($895-$1,895 per fellow), consulting for medical device R&D, on-site and virtual workshops, and access to training centers in Bolton, MA (12 workstations, capacity 100) and Büchenbach, Germany (6 workstations, capacity 36). Distribution is primarily direct via endosim.com e-commerce and a specialist sales team, supplemented by an exclusive US distribution partnership with Fujifilm for EndoGel synthetic models and equipment integrations with Olympus and Boston Scientific.

EndoSim's customer base spans gastroenterology fellows and attending physicians (the primary segment), general surgeons, urologists, OB/GYNs, pulmonologists, spine surgeons, anesthesiologists, interventional radiologists, GI fellowship programs, and medical device companies using its facilities for prototype testing. The company operates as a privately held, founder-owned LLC with no disclosed external funding, an 11-50 employee footprint, and a wholly-owned German subsidiary (ENDOSIM Europe GmbH) supporting EMEA workshop operations.

Name

EndoSim

Legal name

EndoSim LLC

Website

https://endosim.com

Company type

Private

Founded year

2010

Operating status

Operating

Headcount range

11–50 employees

Short description

EndoSim LLC (founded 2010, Bolton, MA) develops evidence-based hybrid simulation models combining reusable hardware trainers with ex-vivo animal tissue specimens for endoscopic, laparoscopic, and multi-specialty procedural training of physicians and fellows globally.

Ownership category

akta.pro rank

Product category

Medical Simulation Equipment

NAICS

Medical Equipment and Supplies Manufacturing (3391), Surgical Appliance and Supplies Manufacturing (339113), Navigational, Measuring, Electromedical, and Control Instruments Manufacturing (3345)

SIC

Surgical & Medical Instruments & Apparatus (3841), Orthopedic, Prosthetic & Surgical Appliances & Supplies (3842)

akta.pro primary industry

Healthcare & Clinical Simulation (Surgery, Nursing, EMT, Patient Interaction) (EDAFAJAC)

akta.pro secondary industries

Endoscopy Systems & Accessories (Scopes, Cameras, Light Sources, Insufflation) (HLAHADAB), Endoscopic Therapeutic & Access Devices (Trocars, dilators, biopsy/ablation tools) (HLAHADAN), Advanced Endoscopy (ERCP/EUS/Interventional) (HLAKAEAC), Endourology & Minimally Invasive Urologic Surgery (HLAKAOAF)

Keywords

• Medical simulation equipment
• Endoscopy training devices
• Surgical skills trainers
• Ex-vivo tissue models
• Medical education hardware

Headquarters

HQ city

Bolton

HQ country

United States

HQ region

North America

Offices3 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Technology or R&D, Operations, Personnel, Marketing or Sales, Infrastructure

Revenue model

1. Simulator Hardware Sales: Sale of reusable plastic/metal trainer simulators (EASIE-R series, LapEASIE-R, UroEASIE, HystoEASIE, PulmoEASIE) priced from $1,475 to $3,895 for purchase, with weekly rentals starting at $250-$315.
2. Specimen Sales: Sale of disposable ex-vivo animal tissue specimens for use with simulators. Specimens include Upper GI ($145-$295), Lower GI ($225-$295), ERCP ($85-$350), EUS ($245-$455), and procedure-specific specimens.
3. Training Services and Workshops: On-site and virtual training programs including the GI Fellowship Training Program ($895-$1,895), international workshop support, and custom simulation training at their facilities in USA and Germany.
4. Consulting and Product Development: R&D consulting services for organizations developing new medical technologies, including feasibility and efficacy studies using their simulation infrastructure.

Pricing tiers

Go-to-market motion2 records

Distribution channels6 records

Marketing channels6 records

Core offering

EndoSim develops, manufactures, and sells hybrid medical simulation models that pair reusable plastic/rubber hardware trainers (EASIE-R, LapEASIE-R, UroEASIE, HystoEASIE, PulmoEASIE, TEST, Proctoscopy, Lumbar Spine, AerosolBarrier) with disposable ex-vivo animal tissue specimens and fully synthetic EndoGel models for healthcare professional training in endoscopic and surgical procedures. The company also delivers fee-based training programs including the GI Fellowship Training Program, augmented reality remote training, on-site workshops, and product/R&D consulting for medical device developers.

Product overview

EndoSim is an innovative, research-oriented company producing realistic simulation models for healthcare provider training using a two-component approach: plastic trainers (hardware) combined with disposable ex-vivo animal tissue specimens (software). The core product lines include the EASIE-R simulator series (R1, R3, R4, R5) for gastrointestinal endoscopy, LapEASIE-R for laparoscopic surgery, UroEASIE for urology, HystoEASIE for gynecology, and PulmoEASIE for pulmonary procedures. The company also offers synthetic training alternatives like EndoGel for ESD and POEM procedures, the Thompson Endoscopic Skills Trainer (TEST) for skill assessment, and the AerosolBarrier intubation box. Supporting services include GI Fellowship Training Programs with equipment rental, augmented reality remote training via video conferencing, workshop organization worldwide, and access to training facilities in Bolton, MA and Büchenbach, Germany. The company's hybrid models combining real ex-vivo animal tissue with rubber or plastic provide realistic haptic feedback validated through 60+ peer-reviewed publications.

Differentiator

Problem solved

Functional benefit

Brands

• EASIE-R: EASIE-R series simulators for endoscopic training including EASIE-R1, R3, R4, and R5 models
• Thompson Endoscopic Skills Trainer (TEST)
• EndoGel
• AerosolBarrier

Products and services

• EASIE-R5 Simulator The newest EASIE-R series model with a torso-shaped tray and mannequin head simulating esophageal intubation; supports both upper and lower GI specimens, ERCP fluoroscopy simulation without X-ray, and EndoGel synthetic inserts. Priced from $3,495. For gastroenterology training programs and endoscopy labs.
• EASIE-R4 Simulator Redesigned EASIE-R model with improved specimen installation, ERCP and EUS attachments, and simulated fluoroscopy without X-ray. Priced from $3,295. For gastroenterology training programs.
• EASIE-R1 Simulator Compact EASIE-R model for EUS and NOTES procedures, available with acrylic cover, laparoscopic top, or PEG top configurations. Purchase from $3,395; rental $250-$315/week. For gastroenterology and surgical training programs.
• Thompson Endoscopic Skills Trainer (TEST) Portable training tool broken into five task-oriented compartments developing specific endoscopic skills including retroversion, polypectomy, torque, knob control, and navigation/loop reduction. Distinguishes skill levels from novice to advanced endoscopist. TEST Box with case $12,995; without case $12,495. For GI fellowship programs and endoscopy skills assessment.
• LapEASIE-R Simulator Laparoscopic simulator with dome-shaped top, 25 rubber ports, and tablet/monitor display options for use with deconstructed task modules and ex-vivo porcine specimens. Purchase $1,956.50-$3,495; rental $275-$475/week. For general surgery and laparoscopic training programs.
• Compact LapEASIE-R Laparoscopic Simulator Compact laparoscopic simulator with adjustable LED lighting and HD USB camera, compatible with task modules, synthetic models, and ex-vivo porcine specimens. Starter Package $995; Pro Package $1,295; rental $285/week. For surgical residency programs and outpatient training labs.
• UroEASIE-2 Simulator Realistic simulator for cystoscopy and ureteroscopy using commercially available urological instruments, with proprietary fluoroscopy camera setup for kidney stone management via lithotripsy or extraction. Purchase $3,895; rental $250/week. For urology training programs and fellowship labs.
• UroEASIE Simulator Allows realistic simulation of interventional cystoscopy and ureteroscopy procedures using real tissue ex-vivo organ packages for training with commercially available urological devices. For urology residency and fellowship programs.
• HystoEASIE Simulator Realistic simulator for interventional hysteroscopy procedures using real tissue ex-vivo organ packages, lightweight and compact with improved durability for resecting artificial myomas. Purchase $1,475; rental $250/week. For OB/GYN residency and fellowship programs.
• PulmoEASIE Simulator Realistic platform for performing pulmonary procedures using porcine or lung specimens with artificial tumors or bleeding scenarios. Purchase $2,895. For pulmonology and thoracic surgery training programs.
• Lumbar Spine Model Hybrid simulation model with realistic lumbar spine vertebrae from ileum to T12, spinal cord, dura with CSF, nerve roots, ligamentum flavum, and real ex-vivo porcine tissue. Purchase $1,585. For spine surgery training and minimally invasive spinal procedure education.
• Proctoscopy Simulator Simulation model of the anus used with anus/rectum cartridges for hindgut and proctoscopy training. Purchase $785; rental $250/week. For gastroenterology and colorectal training programs.
• AerosolBarrier(TM) Intubation Box Reusable protective shield for protecting physicians and nurses during endotracheal intubation or upper GI endoscopy, with rear-facing 5-inch ports and silicone seals to limit airborne virus exposure. $285/unit; silicone ports $16.95 each. For anesthesiology, emergency medicine, and endoscopy departments.
• EndoGel ESD Model Fully synthetic endoscopic training platform for practicing Endoscopic Submucosal Dissection (ESD) procedures, eliminating need for animal-based models while maintaining realistic tissue simulation. Compatible with standard clinical endoscopy systems and EASIE-R platform. $495. For GI fellowship and advanced endoscopy training programs.
• EndoGel POEM Model Synthetic training model for Peroral Endoscopic Myotomy (POEM) procedures, fully portable and compatible with the EASIE-R Simulator Platform. $575. For advanced GI fellowship programs and third-space endoscopy training.
• Upper GI Specimen Porcine ex-vivo esophagus-stomach-duodenum specimen available in standard, MEGA/POEM, with esophageal stricture, or with small bowel configurations. $145-$295 per specimen. For use with EASIE-R simulators in GI training programs.
• Lower GI Specimen Bovine or Porcine ex-vivo colon specimen for EMR/ESD training and stricture management. $225-$295 per specimen. For use with EASIE-R simulators in lower GI training programs.
• ERCP Neopapilla Cartridge Specimen Hybrid ERCP model with porcine ex-vivo duodenum and artificial major papilla made of chicken heart tissue, allowing multiple sphincterotomies in the same specimen. $85-$350. For ERCP training programs and therapeutic endoscopy fellowships.
• EUS Complete Specimen Complete porcine ex-vivo upper GI tract model with esophagus, stomach, duodenum, liver, pancreas, and kidneys, with perfusable aorta for Doppler simulation, for diagnostic and therapeutic EUS training. $245-$455. For advanced EUS fellowship training programs.
• Upper/Lower Gastrointestinal Bleeding Specimen Porcine ex-vivo esophagus-stomach-duodenum specimen or Bovine Colon Specimen with 5-6 bleeding vessels sutured into the specimen for hemostasis training including injection, cautery, clipping, and suturing. For GI hemostasis training programs.
• Upper/Lower Gastrointestinal Polypectomy Specimen Upper GI specimen with 10-15 artificial polyps or Lower GI bovine/porcine colon specimens with 10-15 polyps for polypectomy training. $295 each. For polypectomy skills training in GI fellowship programs.
• Complete Porcine Explant Specimen Complete porcine ex-vivo upper and lower GI tract organ package (esophagus-stomach-duodenum-liver-pancreas-colon-rectum) for various surgical procedures including cholecystectomy and colectomy. For general surgery and laparoscopic training programs.
• GI Fellowship Training Program Complete hands-on training program for GI fellows to train in basic and advanced endoscopic procedures at their home institution, including simulator rental, specimen materials, and optional endoscopic tower rental. Four package options ranging from $895 to $1,895. For GI fellowship program directors and academic medical centers.
• Augmented Reality Training Remote virtual hands-on training via online video conferencing where participants use their own training stations with audiovisual software enabling picture-in-picture procedure view and real-time tutor feedback with augmented reality overlays. For global customers unable to attend on-site training.
• Workshop Organization Services Turnkey solutions for workshop needs including EASIE-R simulators, specimens, international workshop support, and management in USA, Europe, South America, Japan, and Korea. Encompasses custom simulation models, workshop management, product consulting, product development, prototype development and testing, research and assessment, and sales support. For medical conferences, academic institutions, and medical device companies.
• Training Center Access (USA and Europe) Physical training facilities for hands-on workshops and conferences. USA center in Bolton, MA (12 endoscopic workstations, 7,500 ft², capacity 100 participants); Europe center in Büchenbach, Germany (6 workstations, 165 m², capacity 36 participants). Equipped with Olympus towers and endoscopes. For medical conferences, academic institutions, and training program organizers.

Quantifiable outcome

• Research demonstrates improvement in practitioner performance and patient outcomes through use of these simulation models
• +1 more outcomes

Segments10 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Three partnerships are on record, tiered core and minor.

• FujifilmcoreChannel Partner/ Reseller/ DistributorEndoSim partnered with Fujifilm as the exclusive distributor of EndoGel synthetic training models in the United States. EndoGel simulates the texture of human tissue involved in ESD and POEM procedures, providing clinicians with a life-like simulation experience.
• Boston ScientificminorGTM or Marketing PartnerBoston Scientific educational requests are handled through EndoSim's website, indicating a partnership for medical education and training support related to Boston Scientific products and procedures.
• OlympuscoreTechnology or IntegrationEndoSim's European training center in Büchenbach, Germany is equipped with Olympus towers and endoscopes. The partnership enables realistic hands-on training using industry-standard endoscopic equipment.

Scale indicators6 records

Recent moves7 records

Expansion highlights6 records

Direct peers

• Surgical Science: Sweden-based simulation company offering virtual reality training systems for laparoscopy, endoscopy, and interventional procedures. Direct competitor across multiple EndoSim specialties (GI, urology, OB/GYN), with stronger software-defined offering versus EndoSim's hybrid tissue approach.
• Limbs & Things: UK-based medical training product manufacturer focused on task trainers and synthetic simulation models for procedural skills. Comparable as a competitor in hands-on physical simulation across procedural specialties, with similar hybrid hardware-plus-consumable commercial model.
• VirtaMed: Swiss-based developer of high-fidelity virtual reality simulators for endoscopy, laparoscopy, and OB/GYN procedures. Direct competitor in the GI endoscopy simulation space where EndoSim's EASIE-R series operates, with overlapping target customers (fellowship programs and academic medical centers).
• Kyoto Kagaku: Japanese manufacturer of medical training models including phantoms and simulators for GI endoscopy, ultrasound, and procedure training. Comparable as a competitor in physical (non-VR) medical simulation across multiple specialties, with strong Asia-Pacific presence overlapping EndoSim's Japan/Korea markets.

Broad incumbents

• CAE Healthcare: Division of CAE Inc. providing a broad portfolio of medical simulation products including patient simulators and procedural trainers. Competes indirectly across EndoSim's multi-specialty footprint but at a much broader scale with VR/AR-based solutions rather than ex-vivo tissue models.
• Simbionix (3D Systems): 3D Systems' healthcare division (formerly Simbionix) offers the GI Mentor and bronchoscopy/laparoscopy VR simulators. Directly comparable as a competitor in endoscopic and surgical simulation training, but operates at a much larger scale and broader portfolio across multiple medical specialties.

Emerging players

• SynDaver Labs: US-based manufacturer of synthetic human tissue and organ models for medical training and surgical simulation. Closest comparable to EndoSim's EndoGel synthetic platform — both target the elimination of animal-based training with realistic synthetic alternatives.
• Inovus Medical: UK-based developer of low-cost surgical and laparoscopic simulation products. Competes with EndoSim's LapEASIE-R line on price-sensitive accounts and emerging markets, with a more focused product range.
• Chamberlain Group: US manufacturer of synthetic tissue models and task trainers for medical education and device development. Comparable to EndoSim's hybrid hardware approach, with overlap in procedure-specific models and OEM-style development for medical device companies.
• Mentice: Swedish provider of endovascular and interventional procedure simulation. Overlaps with EndoSim's interventional radiology customer segment but with a pure VR/software approach, representing an adjacent rather than direct competitor in the same hospital procurement budgets.

Market position

Strengths5 records

Weaknesses3 records

Competitive moat5 records

Key risks6 records

Key highlights6 records

Customer concentration

• Facebookfacebook.com/endosim
• LinkedInlinkedin.com/company/endosim

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Subsidiaries1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about EndoSim