SIAT

What SIAT does

SIAT (Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences) is a state-affiliated, non-profit research institute headquartered at 1068 Xueyuan Avenue in Shenzhen University Town, operating under the Chinese Academy of Sciences as parent organization. Founded in 2006, the institute has grown to nine specialized research institutes spanning Robotics & AI, Biomedical and Health Engineering, Advanced Computing and Digital Engineering, Biomedicine and Biotechnology, Brain Cognition and Brain Disease, Synthetic Biology, Advanced Materials Science and Engineering, Carbon Neutrality, and Scientific Instrumentation. Its portfolio also includes a joint institute with The Chinese University of Hong Kong (SIAIT), the State Key Laboratory of Quantitative Synthetic Biology, the Shenzhen Synthetic Biology Infrastructures (one of the world's largest fully automated high-throughput synthetic biology facilities), and the only national-level Industrial Innovation Center for Biomanufacturing in China.

The institute's outputs include market-approved medical devices (Dual-Frequency IVUS System approved June 2026), research-grade devices and instruments (NeuroWorm BCI electrode, Helixoft magnetic microrobotic system, Magnetofluid Occlusion Technology, AC-bias capacitance perovskite X-ray detectors), industrial integration software (Device-Edge-Cloud OT/IT Convergence architecture), scientific forecasting models (24-hour typhoon rapid intensification ensemble deployed at China's National Meteorological Center), biotechnology platforms (AAVLINK for large-gene gene therapy, PRINCE small-molecule CRISPR switches), autonomous research systems (MARS multi-agent materials discovery), and advanced materials (composite superionic electrolytes at 10.2 mS cm-1 ionic conductivity). These are documented through high-impact publications in Nature, Science, Cell, Matter, Neuron, Nature Methods, and Nature Biomedical Engineering.

SIAT's business model is structured around two revenue streams: government research funding from CAS, MOST, NSFC, and provincial/municipal science and technology commissions; and technology transfer, licensing, and commercialization of selected research outputs (e.g., IVUS market approval). Commercial pricing is not applicable. Distribution occurs via peer-reviewed publications (global academic audience), direct technology transfer to industrial enterprises (regional), government deployment (e.g., National Meteorological Center, domestic), and medical device commercialization through regulatory approval pathways. The go-to-market posture is community-led, with reach through conferences (CAS-MPG Summer School, ASM-SIAT Symposium, GRIBOI 2026), scientific publications, and industry partnership programs.

Name

SIAT

Legal name

Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences

Website

https://english.siat.cas.cn

Company type

Private

Founded year

2006

Operating status

Operating

Short description

SIAT is a government-affiliated research institute under the Chinese Academy of Sciences, operating nine specialized research institutes in Shenzhen, China, conducting multi-disciplinary research in robotics, biomedicine, synthetic biology, brain science, advanced materials, and carbon neutrality, with technology transfer to industry.

Ownership category

akta.pro rank

Product category

Scientific Research Institute

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714), Analytical Laboratory Instrument Manufacturing (334516), Navigational, Measuring, Electromedical, and Control Instruments Manufacturing (33451), Electromedical and Electrotherapeutic Apparatus Manufacturing (334510)

SIC

Services-Commercial Physical & Biological Research (8731), Laboratory Analytical Instruments (3826), Electromedical & Electrotherapeutic Apparatus (3845), Optical Instruments & Lenses (3827)

akta.pro primary industry

AI/ML-Enabled Biologic Discovery Platforms (computational design, in silico screening) (HLAAAIAE)

akta.pro secondary industries

Microscopy, Imaging & Flow Cytometry Instruments (HLAGAIAE), Scientific Data Management & Data Platforms (SDMS/Data Lakehouse for R&D) (HLAGAJAC), Sensor Fusion, Interface ICs & Modules (AFE/Readout/Packaging/Calibration) (HDAHALAO), Organoids & Organ-on-Chip (regenerative models) (HLAAAGAD), Digital & AI-Enabled Diagnostics (algorithmic interpretation, decision support tied to assays) (HLAAALAO)

Keywords

• Scientific research institute
• Biomedical engineering
• Synthetic biology
• Advanced materials research
• Technology transfer

Headquarters

HQ city

Shenzhen

HQ country

China

HQ region

Asia

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Technology or R&D, Operations, Infrastructure

Revenue model

1. Government Research Funding: SIAT receives funding from Chinese Academy of Sciences, Ministry of Science and Technology of China (MOST), National Natural Science Foundation of China (NSFC), Guangdong Province Department of Science and Technology, and Shenzhen Science and Technology Innovation Commission.
2. Technology Transfer and Industrial Cooperation: The institute engages in industry cooperation and technology transfer, including the Dual-Frequency IVUS System gaining market approval, representing commercialization of research outcomes.

Go-to-market motion1 record

Distribution channels4 records

Marketing channels4 records

Core offering

SIAT conducts multi-disciplinary applied research across nine specialized institutes covering robotics and AI, biomedical engineering, biomedicine, brain science, synthetic biology, advanced materials, carbon neutrality, and scientific instrumentation. Its commercial outputs include the Dual-Frequency IVUS medical imaging system (market-approved), the Device-Edge-Cloud OT/IT Convergence technology platform, the NeuroWorm implantable brain-computer interface electrode, the MARS autonomous materials discovery platform, the AAVLINK gene therapy platform, the BT-YOLO environmental monitoring algorithm, composite superionic electrolytes for solid-state batteries, and an artificial ocean carbon recycling system.

Product overview

SIAT (Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences) is a research institute that develops scientific technologies and instruments rather than commercial consumer products. Its technology portfolio includes medical devices (Dual-Frequency IVUS System, NeuroWorm brain-computer interface electrode, Helixoft microrobotic system, Magnetofluid Occlusion Technology), industrial software (Device-Edge-Cloud OT/IT Convergence Technology), scientific software (Tropical Cyclone Rapid Intensification Forecast Model, BT-YOLO Algorithm), biotechnology platforms (AAVLINK for gene therapy, CABLE neuroimaging method, MARS autonomous materials discovery system), and advanced materials (Superionic Electrolytes for solid-state batteries, Ocean Carbon Recycling System). The Dual-Frequency IVUS System represents their primary market-approved medical device product.

Differentiator

Problem solved

Functional benefit

Brands

• Shenzhen Synthetic Biology Infrastructures: One of the world's largest fully automated, high-throughput synthetic biology infrastructure facilities
• National Industrial Innovation Center for Biomanufacturing

Products and services

• Dual-Frequency IVUS (Intravascular Ultrasound) System Market-approved intravascular ultrasound imaging system for coronary vessel assessment that provides superior imaging of plaque and calcification compared with standard coronary angiography. Intended for clinical cardiology use.
• Device-Edge-Cloud OT/IT Convergence Technology and System Industrial software platform that integrates OT and IT domains through a device-edge-cloud architecture for manufacturing digital transformation; supports heterogeneous device integration, edge control, and cloud-based decisioning. Targeted at manufacturers, pharmaceutical firms, and fine chemical enterprises.
• CABLE (Cytoarchitecture-Based Link Estimation) Neuroscience research tool for 3D whole-brain fiber tract reconstruction from routine histology at cellular resolution, eliminating the need for genetic labeling or viral tracers. For brain mapping researchers and neuroscience laboratories.
• NeuroWorm — Movable Long-term Implantable Soft Microfibre Electrode Soft, long-term implantable, magnetically steerable microfibre electrode for dynamic brain-computer interfaces with up to 60 independent signal channels. Enables repositionable neural and muscle recording for neuroscience research and clinical BCI applications.
• MARS (Multi-Agent and Robot System) End-to-end autonomous materials discovery platform that orchestrates 19 LLM-based research agents and 16 domain-specific tools including robotic experimentation for closed-loop materials R&D. For materials science research groups.
• AAVLINK (AAV with translocation LINKage) Biotechnology platform for in vivo reassembly of large therapeutic genes delivered via AAV vectors, enabling treatment of diseases requiring oversized gene cargo. Developed jointly with Peking University First Hospital for gene therapy applications.
• BT-YOLO Algorithm for Bioluminescent Algal Bloom Monitoring Computer vision algorithm for real-time pixel-level segmentation of bioluminescent algal blooms ("blue tears") in video footage, enabling quantitative environmental monitoring.
• Magnetofluid Occlusion Technology for Left Atrial Appendage Closure Magnetic fluid-based medical device technology for controllable left atrial appendage occlusion, developed with Fuwai Hospital to overcome limitations of metallic occlusion implants for stroke prevention in atrial fibrillation.
• PA-LiMPS/PEO Composite Superionic Electrolyte Composite superionic solid electrolyte with perpendicularly aligned 2D Li-ion pathways for pressure-less all-solid-state lithium batteries, delivering liquid-electrolyte-comparable ionic conductivity with mechanical flexibility. For battery materials and device manufacturers.
• Artificial Ocean Carbon Recycling System Carbon capture and conversion system that removes CO2 from seawater and directly converts it into succinic acid via an electrochemical-microbial fermentation cascade, achieving 70% efficiency over 530+ hours. For carbon neutrality and bio-based chemical production.
• Machine Learning Ensemble Model for Tropical Cyclone Rapid Intensification Forecast Operational machine-learning forecasting model for typhoon rapid intensification, deployed at China's National Meteorological Center and outperforming US National Hurricane Center baselines. For meteorological services and severe weather early warning.
• Helixoft Magnetic Soft Microrobotic System Helix-shaped magnetic soft microrobot system for active navigation in narrow luminal interventions, providing continuous stiffness tuning and precise steering. For minimally invasive medical device and interventional robotics applications.

Quantifiable outcome

• Carbon capture efficiency of 70% over 530+ hours of continuous operation
• +3 more outcomes

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability18 records

Feature10 records

Partnerships

Eleven partnerships are on record, tiered flagship, major and core.

• BRICS Countries Technology ForumflagshipStrategic or Co-development Partner · 27 May 2026SIAT's Device-Edge-Cloud Integration Technology was included in the Promotion List of Advanced and Appropriate Technologies for BRICS Countries during the 2026 BRICS New Industrial Revolution Partnership Forum in Xiamen, recognizing the technology's suitability for BRICS manufacturing environments.
• University of AberdeenmajorStrategic or Co-development Partner · 23 April 2026SIAT and University of Aberdeen launched an International Joint Laboratory for Energy Metabolism, establishing a formal collaborative research framework for joint studies in energy metabolism research.
• China Space Station / Shenzhou-22 MissionflagshipStrategic or Co-development PartnerCollaborative research with China's Space Station program for space embryology experiments, successfully recovering experimental samples studying effects of space conditions on mammalian early embryo development.
• University of Science and Technology of ChinamajorStrategic or Co-development PartnerJoint research with University of Science and Technology of China on synaptic transmission using time-resolved cryo-electron tomography, led by Prof. BI Guoqiang.
• Peking University First HospitalmajorStrategic or Co-development PartnerCollaboration with Peking University First Hospital for AAV gene therapy research developing AAVLINK technology for large gene cargo delivery.
• Fuwai Hospital, Chinese Academy of Medical SciencesmajorStrategic or Co-development PartnerJoint research with Fuwai Hospital on magnetofluids for left atrial appendage occlusion, combining SIAT's materials expertise with clinical medical research.
• City University of Hong KongmajorStrategic or Co-development PartnerCollaborative research with Prof. Alex K.-Y. Jen's team on perovskite solar cell stability using in-situ cross-linking strategy.
• Chinese Academy of SciencesflagshipStrategic or Co-development PartnerSIAT is an integral institute under the Chinese Academy of Sciences, receiving institutional support, research funding through CAS programs, and collaborative opportunities with other CAS institutes.
• Shenzhen Institute of Advanced Integration Technology (SIAIT)coreStrategic or Co-development PartnerJoint institute with The Chinese University of Hong Kong (CUHK) for advanced integration technology research.
• University of Electronic Science and Technology of ChinamajorStrategic or Co-development PartnerCollaboration with Prof. XIA Chuan's team on artificial ocean carbon recycling system combining electrochemistry with microbial fermentation.
• South China University of TechnologymajorStrategic or Co-development PartnerJoint research with Prof. HU Renzong on composite superionic electrolytes for solid-state batteries.

Scale indicators6 records

Recent moves6 records

Expansion highlights6 records

Regional players

• Westlake University: Emerging private research university in Hangzhou, China, focused on basic sciences and advanced technology with a modern institute model. Comparable as a young, well-funded Chinese research institution competing for talent and grants in adjacent geographic markets.

Direct peers

• Francis Crick Institute: UK's flagship biomedical discovery institute with ~1,500 scientists working across cancer, infection, neuroscience, and computational biology. Comparable single-site, multi-disciplinary biomedical research model with strong publication output.
• Institut Pasteur: Non-profit research foundation with institutes spanning microbiology, immunology, neuroscience, and developmental biology. Comparable as a mission-driven, non-commercial life sciences research institution with technology transfer pipelines.
• Broad Institute: Joint Harvard/MIT biomedical and genomic research institute with strong programs in synthetic biology, computational biology, and disease research. Closest analog to SIAT's synthetic biology, genomics, and AI-enabled discovery activities.
• RIKEN: Japan's flagship national multi-disciplinary research organization covering physics, chemistry, biology, brain science, and computational science. Comparable to SIAT as a government-funded, multi-institute research enterprise spanning basic and translational work.
• MRC Laboratory of Molecular Biology: UK Medical Research Council laboratory focused on molecular biology, neurobiology, and structural biology with strong Nobel-tradition publication record. Comparable in life sciences research depth and translational outputs.

Emerging players

• Ginkgo Bioworks: US synthetic biology platform company building automated, high-throughput 'foundries' for engineered organisms — comparable to SIAT's Shenzhen Synthetic Biology Infrastructures from a commercial-operator perspective. Useful as a commercial analog and potential partner/licensee.

Broad incumbents

• CNRS (Centre national de la recherche scientifique): France's largest public scientific research organization with 1,000+ labs across physics, chemistry, biology, and engineering. Comparable multi-disciplinary public-sector research scale and breadth of operation.
• Max Planck Society: Germany's largest non-university research organization, operating 80+ Max Planck Institutes across life sciences, materials, and AI. Comparable to SIAT in funding model, scale of operations, and focus on frontier science with strong publication output.
• Helmholtz Association: Germany's largest scientific organization running 18 research centers with federal funding for energy, health, materials, and earth-system research. Comparable in scale, public funding model, and large-facility mandate (similar to SIAT's synthetic biology infrastructure).

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/8077125/admin/dashboard
• Xx.com/SIATnews
• Facebookfacebook.com/profile.php

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Subsidiaries12 records

Funding overview

Funding rounds

Investors

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M&A

Investments5 records

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about SIAT