What MAK-SYSTEM International does

MAK-SYSTEM International is a Paris-founded (1984), London-headquartered private healthcare software company that builds mission-critical information systems for blood establishments, plasma centres, hospital transfusion services, and cell/tissue/gene therapy organizations. Its portfolio spans four core products: eProgesa (a Blood Establishment Computer System, or BECS, handling 20,000 to 6 million units per year), P.H.S/eTraceLine (hospital transfusion management and reference lab software), Cosmas (cell, tissue and gene therapy orchestration supporting chain-of-identity and chain-of-custody for CAR-T and ATMP workflows), and eDRM (donor relationship management). All products are FDA 510(k) cleared or CE-marked under EU MDR 2017/746, and the suite is delivered either on-premise or via MAK.care, a cloud managed services platform launched in 2022 and built on AWS.

The technology stack is Java-based, cloud-native, and platform-agnostic with a service-oriented architecture designed for high-availability, multi-region resilience, and on-demand autoscaling. MAK.care extends the platform with a 24/7 global Security Operations Center, ransomware protection, encrypted cloud-native backups, and AI-powered observability. The company claims to manage approximately 1 in 3 blood transfusions globally, processing more than 30 million blood donations per year across 35 countries, with offices in the UK, US, France, Spain, Germany, Serbia, and North Macedonia. Notable customers include the New York Blood Center (10-year MAK.care deal), New Zealand Blood Service, Welsh Blood Service, and Northern Ireland Blood Transfusion Service.

MAK-SYSTEM generates revenue through software licensing and subscriptions for its four core products, multi-year managed services contracts on MAK.care (typically 10 years, priced via transaction fee or subscription with full cost visibility), and professional services for implementation, configuration, training, and post go-live support. Go-to-market is sales-led with a Global Commercial Director and Strategic Account Directors driving direct enterprise field sales to blood centres, hospitals, and biopharma customers globally, supplemented by a strong conference and event presence (AABB, ISCT, SABM), the long-standing International MAK User Group (IMUG) community, and a strategic AWS partnership. In July 2026, MAK-SYSTEM was acquired by Invita Health to extend end-to-end blood management solutions to organizations worldwide.

Name

MAK-SYSTEM International

Legal name

MAK-SYSTEM Ltd

Website

https://mak-system.com

Company type

Private

Founded year

1984

Operating status

Operating

Headcount range

251–500 employees

Short description

MAK-SYSTEM International provides FDA-cleared and CE-marked healthcare software for blood establishments, plasma centres, hospital transfusion services, and cell/tissue/gene therapy organizations, managing roughly one in three global blood transfusions across 35 countries through its eProgesa, P.H.S/eTraceLine, Cosmas, and MAK.care cloud managed services platform.

Ownership category

akta.pro rank

Headquarters

HQ city

Paris

HQ country

France

HQ region

Europe

Offices7 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Operations, Infrastructure, Marketing or Sales, Supply Chain

Revenue model

1. Software Licensing and Subscription: Traditional on-premise and cloud-hosted software licensing for ePROGESA, P.H.S/eTraceLine, Cosmas, and eDRM products. Can be deployed as on-premise or on-cloud (MAK.care) options.
2. Managed Services (MAK.care): Full digital ecosystem management on behalf of clients delivered as managed service. Financial model offers full price visibility over contract term (typically 10 years) via transaction fee or subscription model. MAK manages entire digital ecosystem including backups, patching, 24/7 infrastructure, security operations, incident management, disaster recovery, and observability.
3. Professional Services: Implementation services including configuration, project management, training, and post go-live support. Turn-key services to speed up implementation process and help with digital transformation.

Pricing tiers

Go-to-market motion3 records

Distribution channels3 records

Marketing channels5 records

Core offering

MAK-SYSTEM designs, develops and delivers regulated healthcare software for managing blood, plasma, tissue and cell products from donation to clinical application. Its portfolio includes eProgesa (BECS), P.H.S/eTraceLine (hospital transfusion), Cosmas (cell/gene therapy orchestration) and eDRM (donor relationship management), available on-premise or as the MAK.care cloud managed service on AWS.

Product overview

MAK-SYSTEM offers a portfolio of advanced healthcare software solutions for managing blood, plasma, tissue, and cellular products from donation to clinical application. The product suite consists of: eProgesa (BECS for blood and plasma center management), P.H.S/eTraceLine (hospital transfusion management), Cosmas (cell, tissue and gene therapy orchestration), and eDRM (donor relationship management). These products are delivered either on-premises or via the MAK.care cloud managed services platform, enabling end-to-end automation from vein-to-vein.

Differentiator

Problem solved

Functional benefit

Brands

• eProgesa (ePro): End-to-end blood and plasma management software for blood and plasma centers, enabling automation from donor recruitment through collection, processing, testing, release, inventory management, shipping and hospital ordering.
• P.H.S / eTraceLine (eTL)
• Cosmas / TCS
• eDRM
• MAK.care

Quantifiable outcome

• 1 in 3 blood transfusions globally managed through MAK-SYSTEM systems
• +3 more outcomes

Named customers4 records

Segments4 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration6 records

AI capability2 records

Feature5 records

Partnerships

Seven partnerships are on record, tiered minor and core.

• WOMEN'STECminorGTM or Marketing Partner · 1 November 2025Seven-year partnership supporting Digital Skills Development Programme for Women in Northern Ireland. Programme helps women gain essential IT and digital qualifications covering AI tool training, cybersecurity essentials, online safety, and digital career pathways.
• Northern Ireland Blood Transfusion ServicecoreStrategic or Co-development Partner · 15 May 2024Strategic partnership announced by NI Health Minister Robin Swann on May 15, 2024 to deliver state-of-the-art blood management system. First of its kind in UK and Europe enabling full blood tracking from donation to recipient. Replaces a 25-year-old system with end-to-end digital vein-to-vein donor management, blood production and tracking.
• New Zealand Blood ServicecoreStrategic or Co-development Partner · 11 February 2024First national service managing blood and controlled human substances to transition to MAK.care cloud platform. Went live February 11, 2024 with full end-to-end automation of nationwide vein-to-vein operations from blood donation to transfusion, securely managed in the cloud.
• New York Blood CentercoreStrategic or Co-development Partner · 8 June 202310-year strategic partnership using MAK.Care platform to run entire digital ecosystem on behalf of NYBC. First national blood centre in USA to benefit from MAK.Care platform, transforming how blood is managed and delivered to patients.
• Amazon Web Services (AWS)coreTechnology or Integration · 28 April 2023Strategic partnership with AWS allowing more efficient and scalable connectivity for all stakeholders including blood centres, donors, healthcare providers, and pharmaceutical/biotech industries. MAK.care platform built on AWS Well-Architected Framework.
• BytesminorGTM or Marketing PartnerCommunity partnership supporting Bytes' programmes focused on supporting young people, strengthening employability opportunities, and improving digital inclusion across Northern Ireland communities.
• AnthesisminorImplementation/ SI/ Consulting PartnerESG sustainability consultancy partnership providing strategic advice and independent monitoring and benchmarking for MAK-SYSTEM's ESG programme.

Scale indicators4 records

Recent moves6 records

Expansion highlights6 records

Emerging players

• BloodHub: BloodHub is a US-based SaaS vendor providing order management and inventory software specifically for hospital blood banks and blood centers. A more focused, emerging competitor to MAK-SYSTEM's ePROGESA and P.H.S/eTraceLine products in the US market.

Broad incumbents

• Dedalus Group: Dedalus is a major European healthcare IT vendor providing diagnostic, clinical, and laboratory information systems including blood bank management. Overlap with MAK-SYSTEM in transfusion management and European hospital IT, and notably a previous employer of MAK's Chief Delivery Officer Pascal Gilbert-Jeantet.
• Haemonetics Corporation: Haemonetics is a global leader in blood and plasma component management, providing both hardware (blood collection devices) and software solutions for blood centers and plasma collectors. Direct overlap with MAK-SYSTEM's ePROGESA BECS and plasma center offerings, though Haemonetics is broader in scope including plasma collection devices and hemostasis management.
• Sysmex Corporation: Sysmex is a global leader in hematology and hemostasis diagnostics, with software solutions that interface with blood bank workflows. Comparable to MAK-SYSTEM in serving hematology and transfusion laboratories, though primarily a diagnostics hardware/instrument vendor rather than a BECS software vendor.
• Terumo BCT: Terumo BCT provides blood component collection, processing, and storage technologies for blood centers and plasma collectors globally. Comparable customer base to MAK-SYSTEM's ePROGESA deployments, though Terumo is primarily a medical device manufacturer rather than a software vendor.
• Fresenius Kabi: Fresenius Kabi operates one of the world's largest plasma collection networks through its subsidiary and provides blood collection and transfusion medicine products. Adjacent to MAK-SYSTEM's plasma center customer base with overlap in transfusion medicine customers.
• Epic Systems (Blood Bank module): Epic's Beaker and integrated blood bank module is widely deployed in large US health systems and competes with MAK-SYSTEM's hospital-side transfusion management offering. While not a specialized BECS vendor, Epic's hospital EHR dominance creates bundling risk for MAK's P.H.S/eTraceLine product.

Direct peers

• WellSky: WellSky provides healthcare interoperability and specialized software including blood bank and transfusion management solutions. Directly comparable to MAK-SYSTEM's hospital transfusion and blood center software, with overlap in donor management functionality.
• Sunquest Information Systems: Sunquest provides laboratory and blood bank information systems used by hospitals and reference labs globally, including transfusion management solutions. Directly competes with MAK-SYSTEM's P.H.S/eTraceLine for hospital blood bank and transfusion software deployments.

Regional players

• Stratech Scientific: Stratech distributes and supports blood bank and life science instrumentation across the UK and Ireland, often with associated software interfaces. Provides regional competition to MAK-SYSTEM's hospital transfusion deployments in Northern Ireland and the broader UK market.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/mak-system

Compliance9 records

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about MAK-SYSTEM International