PointHealth

What PointHealth does

PointHealth is a San Francisco-based healthcare technology company that combines artificial intelligence with pharmacogenomics (PGx) to deliver personalized medication guidance. The company's core technology integrates patient DNA, medication history, and clinical records through proprietary AI models to generate ranked medication recommendations, drug-drug interaction flags, and gene-drug context, with the company claiming hallucination-free output and sub-10-second response times. It operates three interconnected products: PointHealth Wellness (a direct-to-consumer offering sold at $199 per at-home DNA kit via patient-app.pointhealth.ai), PointHealth Insights (a clinical decision support platform embedded in athenahealth, Epic, Cerner, and Healthie EHR workflows with provider pricing starting at $150 per kit), and PointHealth for Payers (a population health analytics solution targeting health plans on undisclosed contracts). Infrastructure is built on AWS and MongoDB (via the MongoDB for Startups program), with HIPAA-compliant data handling and CLIA-certified lab processing. The company is founder-led by Rachel Gollub (CEO, formerly CTO at Benefitter/UnitedHealth Group) and Joe Waggoner (COO, formerly Sr. Director of AI/ML Engineering at UnitedHealth Group), with Andrew Zinkel serving as Chief Medical Officer. Headcount is reported at 11-50 employees, no external funding rounds are disclosed, and the company is privately held with ownership concentrated in the founders.

Name

PointHealth

Legal name

Point Health AI, Inc.

Website

https://pointhealth.ai

Company type

Private

Operating status

Operating

Headcount range

11–50 employees

Ownership category

akta.pro rank

Product category

Clinical Decision Support Software

NAICS

Medical and Diagnostic Laboratories (62151)

SIC

In Vitro & In Vivo Diagnostic Substances (2835)

akta.pro primary industry

Pharmacogenomics-Informed Medication Optimization Support (HSABALAO)

akta.pro secondary industries

Medication Adherence, Digital Therapeutics & Remote Coaching (condition-specific programs) (HLALAFAF), Healthcare & Wellness Personalization (HDAAAGAI)

Keywords

• Clinical decision support
• Pharmacogenomics testing
• AI medication guidance
• Precision medicine platform
• EHR-integrated analytics

Headquarters

HQ city

San Francisco

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B and B2C

Offering type

Software

Cost components

Technology or R&D, Personnel, Operations, Marketing or Sales, Infrastructure

Revenue model

1. PointHealth Wellness (Patient Direct Purchase): One-time payment of $199 for a DNA cheek swab kit, lab analysis, personalized medication insights, safety review, and a clinical report for the patient's doctor. This is a direct-to-consumer B2C transaction with no subscription.
2. PointHealth PGx Subscription (Provider Channel): Special pricing for providers starts at $150 per order, where providers order DNA kits directly from their EHR system and track results. The kit is introduced during patient visits and completed post-visit by the patient.
3. Payer Analytics & Population Health: PointHealth helps payers reduce avoidable medication-related waste by providing patient-specific medication intelligence. Savings studies show up to $4,000/year in follow-on costs per member due to poor treatment reduction.
4. athenahealth Marketplace Distribution: PointHealth's AI Treatment Decision Support app is available through the athenahealth Marketplace, generating revenue by making the solution accessible to the athenaOne network of over 160,000 providers.

Pricing tiers

Go-to-market motion4 records

Distribution channels4 records

Marketing channels7 records

Core offering

PointHealth combines AI with pharmacogenomics (PGx) to deliver personalized medication guidance. The company sells a patient-facing at-home DNA kit (PointHealth Wellness, $199) and a clinical decision support product (PointHealth Insights) that integrates into provider EHRs (athenahealth, Epic, Cerner, Healthie) to surface drug-gene and drug-drug interaction alerts. It also offers PointHealth for Payers, a population health analytics solution for health plans.

Product overview

PointHealth is a precision medicine platform that combines AI and pharmacogenomics (PGx) to deliver personalized medication guidance. The platform operates as a unified system with three core products: PointHealth Wellness (for patients seeking at-home DNA testing and medication insights), PointHealth Insights (for healthcare providers with clinical decision support integrated into EHR workflows), and PointHealth for Payers (population health analytics for insurers). These products are interconnected through the PGx Vault, which stores genetic data for lifetime access across the platform, and the optional PGx Subscription add-on for providers to order DNA kits directly from their EHR. The platform's AI analyzes patient history, medications, genetics, and clinical context to generate ranked medication recommendations with safety flags, supporting over 160,000 providers through the athenahealth Marketplace integration.

Differentiator

Problem solved

Functional benefit

Brands

• PointHealth Wellness: A patient-friendly experience that explains medication insights in clear language, featuring plain-language guidance and clear medication insights.
• PointHealth Insights

Quantifiable outcome

• 30% reduction in adverse drug reactions
• +6 more outcomes

Named customers2 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration4 records

AI capability5 records

Feature5 records

Partnerships

Seven partnerships are on record, tiered core, strategic and supporting.

• athenahealthcoreTechnology or Integration · 25 February 2026PointHealth AI integrated its AI-powered Treatment Decision Support application into the athenaOne platform through the athenahealth Marketplace program. The integration enables prescribing clinicians to receive real-time, patient-specific treatment guidance directly within their existing clinical workflow. The partnership makes PointHealth available to more than 160,000 providers on the athenaOne network.
• Amazon Web Services (AWS)coreTechnology or IntegrationPointHealth uses AWS infrastructure to power its AI and genomics platform. Featured in an AWS Public Sector blog alongside Protege discussing how the startups transform health treatment recommendations with AI on AWS. AWS provides the cloud infrastructure enabling PointHealth to scale precision medicine for millions.
• MongoDB (MongoDB for Startups)coreTechnology or IntegrationPointHealth AI participates in the MongoDB for Startups program, using MongoDB infrastructure to scale precision medicine and make advanced, individualized care accessible to millions of patients. MongoDB provides the database backbone for PointHealth's AI + PGx platform.
• ProtegestrategicStrategic or Co-development PartnerPointHealth and Protege partnered alongside Amazon Web Services to harness the power of genomics, advanced analytics, and AI in identifying optimal treatment for patients on the first try. Both startups presented their models at the PMWC (Precision Medicine World Conference) with AWS support.
• EpiccoreTechnology or IntegrationPointHealth Insights is designed to integrate with Epic EHR systems, allowing providers to access patient-authorized medication intelligence directly within their Epic workflow without leaving the clinical application.
• CernercoreTechnology or IntegrationPointHealth Insights is designed to integrate with Cerner EHR systems, allowing providers to access patient-authorized medication intelligence directly within their Cerner workflow without leaving the clinical application.
• HealthiesupportingTechnology or IntegrationPointHealth Insights is designed to integrate with Healthie EHR/platform, allowing providers to access patient-authorized medication intelligence within the Healthie platform, particularly relevant for behavioral health and wellness applications.

Scale indicators10 records

Recent moves6 records

Expansion highlights5 records

Emerging players

• Progenity: Progenity is a molecular and precision medicine company that has pursued AI-driven clinical decision support and PGx-related applications. Partial overlap with PointHealth on the genomics + clinical workflow integration thesis.
• Sema4: Sema4 (now part of GeneDx/Sema4 combined entity) is a patient-centered health intelligence company focused on genomics and AI-driven clinical insights. Comparable to PointHealth in combining AI with genomic data for clinical decision support, with stronger established health system relationships.

Direct peers

• Genomind: Genomind is a pharmacogenomics company specializing in mental health and behavioral health medication optimization. Directly comparable to PointHealth's initial behavioral health focus and PGx testing approach, with similar clinical decision support positioning for prescribers.
• Color Health: Color is a population-scale genomics and digital health company offering genetic testing, including pharmacogenomics, integrated with employer and payer programs. Directly comparable to PointHealth on the payer and DTC axes, with similar population health ambitions.
• OneOme: OneOme offers pharmacogenomic testing and clinical decision support tools for healthcare providers, including EHR integration. Directly comparable to PointHealth Insights on provider PGx workflow integration and medication decision support.
• 23andMe: 23andMe is a direct-to-consumer genetic testing company that has expanded into health-related genetic insights including medication response. Directly comparable to PointHealth Wellness on the DTC genetic testing business model and consumer pricing.

Broad incumbents

• Myriad Genetics: Myriad Genetics is an established genetic testing company offering a broad portfolio including pharmacogenomic tests (GeneSight). Overlaps with PointHealth in PGx for medication selection and has much deeper clinical evidence, reimbursement infrastructure, and sales reach.
• Tempus: Tempus is an AI-powered precision medicine company that combines clinical and molecular data to support treatment decisions. Comparable to PointHealth in the AI + genomics for treatment selection thesis, with much broader oncology and broader health system reach.
• GeneDx: GeneDx is a clinical genetic testing company with broad hereditary disease and rare disease testing capabilities. Comparable to PointHealth in DNA-based clinical decision support and EHR-integrated workflows, with significantly larger scale and provider footprint.
• Invitae: Invitae is a medical genetics company offering a broad menu of genetic tests including PGx-relevant panels. Overlaps with PointHealth on clinical-grade DNA testing infrastructure and provider channel relationships, with significantly broader test menu and market presence.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/pointhealth-ai

Compliance4 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles5 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about PointHealth