A-Squared Ventures
A-Squared Ventures is an early-stage venture capital fund founded in 2021 that invests from first-check through Series A in B2B and B2B2C US healthcare software companies. It operates as the healthtech vertical of Arkin Capital, with deal teams in Tel Aviv and the Northeast US.
- Company typePrivate
- Founded2021
- HeadquartersNew York, United States
- Headcount1–10
- GTM typeB2B
- OfferingServices
What A-Squared Ventures does
A-Squared Ventures (A²) is an early-stage venture capital fund focused exclusively on healthcare technology, founded in 2021 as the dedicated healthtech vertical of Arkin Capital, a multi-asset investment manager with over $2 billion under management across 12 funds. The fund invests from first-check through Series A in B2B and B2B2C healthcare IT, tech-centered services, and pharma-tech companies targeting the US market. Its portfolio of 13 companies spans remote patient monitoring (Validic), behavioral health ambient AI (Eleos Health), AI medical interpretation (No Barrier), pharmaceutical compliance (Revisto), population health (Siftwell), federated compute (Rhino Health), virtual care for neurodegenerative conditions (Synapticure), polypharmacy medication adherence (Medminder), care management AI (Laguna Health), surgical data platforms (Care), clinical genomics (Nest Health), and HCP engagement (Edocate).
The fund's core "product" is hands-on venture support rather than a technology platform. Its competitive operation rests on a proprietary database of 3,000+ companies, a curated network of 250+ VC funds and 350+ senior healthcare experts, and on-the-ground deal teams in Tel Aviv and the Northeast US (with Managing Partner Dr. Nadav Shimoni and Partner Dr. Sam Cronin anchoring the partnership). A dedicated Pre-Seed track with Fusion VC extends its upstream deal access, and recurring co-investments with Rock Health Capital and Esplanade Ventures position it as a syndicate anchor. The fund does not publish discrete AUM, fund size, or revenue figures.
Revenue is generated through conventional VC economics — management fees on committed capital and carried interest on successful exits — supplemented by infrastructure and shared resources from Arkin Capital's parent platform. The fund deploys capital sales-led through direct founder relationships, network referrals, and database-driven outbound. As a small team of fewer than 10 employees, the firm's operational scaling is closely tied to Arkin Capital's broader fund platform.
A-Squared Ventures firmographics
Firmographics- Name
- A-Squared Ventures
- Legal name
- Arkin Capital
- Website
- https://asquared.arkin-capital.com
- Company type
- Private
- Founded year
- 2021
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Short description
- A-Squared Ventures is an early-stage venture capital fund founded in 2021 that invests from first-check through Series A in B2B and B2B2C US healthcare software companies. It operates as the healthtech vertical of Arkin Capital, with deal teams in Tel Aviv and the Northeast US.
- Ownership category
- akta.pro rank
A-Squared Ventures industry classification
Industry- Product category
- Healthcare Venture Capital
- NAICS
- Other Investment Pools and Funds (5259)
- SIC
- Finance Services (6199)
- akta.pro primary industry
- Early-Stage Venture Capital (Series A/B) (FSANAAAB)
- akta.pro secondary industry
- Sector-Focused Venture Capital (Vertical Specialists) (FSANAAAD)
Keywords
Where A-Squared Ventures is headquartered
LocationHeadquarters
- HQ city
- New York
- HQ country
- United States
- HQ region
- North America
Offices2 records
Markets served
A-Squared Ventures business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure
Revenue model
- Fund Management: A-Squared Ventures generates returns through management fees on deployed capital and carried interest on successful exits from their portfolio companies. They invest in early-stage healthcare companies from first capital to Series A, with Arkin Capital backing providing infrastructure support across 12 funds.
Go-to-market motion1 record
Distribution channels1 record
Marketing channels4 records
A-Squared Ventures product offering
Product offeringCore offering
A-Squared Ventures (A²) is an early-stage venture capital fund that invests from first capital through Series A in B2B and B2B2C healthcare software companies operating in the US market. The firm provides portfolio companies with hands-on operational support, including GTM strategy refinement, ICP validation, and commercial scaling assistance, while sourcing deals through a proprietary database of 3,000+ companies and a network of 250+ VC funds and 350+ healthcare experts. The fund operates with dual on-the-ground teams in Tel Aviv and the Northeast US, leveraging Arkin Capital's $2B+ infrastructure.
Differentiator
Problem solved
Functional benefit
Quantifiable outcome
- 30+ successful exits across portfolio
Companies that use A-Squared Ventures
Customer profileSegments1 record
Ideal customer profiles1 record
A-Squared Ventures technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
AI capability9 records
A-Squared Ventures partnerships and signals
Strategic signalScale indicators6 records
Recent moves5 records
Expansion highlights5 records
A-Squared Ventures competitors and assessment
Company assessmentBroad incumbents
- Optum Ventures: Corporate venture arm of UnitedHealth Group/Optum, investing broadly across digital health with deeper pockets and strategic distribution. Overlaps A-Squared's thesis but operates with much larger fund size and a strategic LP.
- Bessemer Venture Partners: Long-tenured venture firm with an active healthcare practice spanning provider, payer, and pharma-tech. Comparable in vertical specialization but materially larger in AUM.
- Echo Health Ventures: Strategic venture partnership between Cambia Health Solutions and Mosaic Health Solutions, focused on healthcare innovation across stages. Comparable healthtech-only thesis with strategic-LP backing.
- General Catalyst: Large multi-stage venture firm with a dedicated Healthtech practice across seed to growth. Indirectly competitive for early-stage healthtech deals and a potential co-investor for A-Squared's portfolio companies at Series A+.
- Andreessen Horowitz (a16z Bio + Health): Mega-fund with a dedicated Bio + Health vertical covering digital health and bio. Competes for premium healthcare seed deals and serves as a likely Series B+ lead for A-Squared portfolio companies.
- Kaiser Permanente Ventures: Strategic CVC of Kaiser Permanente, investing in digital health and care delivery innovation. Comparable healthtech focus but with a strategic LP and corporate validation advantage A-Squared lacks.
- GV (Google Ventures): Alphabet's venture arm with broad healthcare exposure across digital health, biotech, and care delivery. Larger fund and brand, but overlapping interest in B2B healthtech seed and Series A opportunities.
Direct peers
- Rock Health Capital: One of the earliest and most established digital health venture funds, deploying seed and early-stage capital into B2B healthtech — directly comparable stage, sector focus, and LP profile to A-Squared Ventures. Frequently appears as a co-investor with A-Squared.
- Flare Capital Partners: Boston-based venture firm exclusively focused on early-stage digital health, with comparable check sizes and a similar B2B healthtech thesis. Direct competitor for the same founder and LP pool.
- Define Ventures: Early-to-growth digital health fund focused on B2B healthtech companies, with a similar investment-stage profile and sector specialization. Competes head-to-head for premium healthtech seed deals.
Market position
Strengths4 records
Weaknesses5 records
Competitive moat5 records
Key risks5 records
Key highlights6 records
Customer concentration
A-Squared Ventures financial estimates
Financial estimateRevenue estimate
Valuation estimate
A-Squared Ventures leadership team
Management profileNumber of profiles
Profiles3 records
A-Squared Ventures funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
A-Squared Ventures M&A and investment
M&A and investmentM&A
Investments1 record
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about A-Squared Ventures
What does A-Squared Ventures do?
A-Squared Ventures (A²) is an early-stage venture capital fund that invests from first capital through Series A in B2B and B2B2C healthcare software companies operating in the US market. The firm provides portfolio companies with hands-on operational support, including GTM strategy refinement, ICP validation, and commercial scaling assistance, while sourcing deals through a proprietary database of 3,000+ companies and a network of 250+ VC funds and 350+ healthcare experts. The fund operates with dual on-the-ground teams in Tel Aviv and the Northeast US, leveraging Arkin Capital's $2B+ infrastructure.
Is A-Squared Ventures a public or private company?
A-Squared Ventures is a private company. It is classified as corporate owned and is currently operating.
When was A-Squared Ventures founded?
A-Squared Ventures was founded in 2021. It employs 1 to 10 people.
Where is A-Squared Ventures based?
A-Squared Ventures is headquartered in New York, United States, in the North America region.
How does A-Squared Ventures make money?
One revenue line is on record: fund Management.
Who are A-Squared Ventures's main competitors?
Broad incumbents on record are Optum Ventures, Bessemer Venture Partners, Echo Health Ventures, General Catalyst, Andreessen Horowitz (a16z Bio + Health), Kaiser Permanente Ventures and GV (Google Ventures). Direct peers are Rock Health Capital, Flare Capital Partners and Define Ventures.
Does A-Squared Ventures have an API?
No public API is recorded for A-Squared Ventures.
What industry is A-Squared Ventures in?
A-Squared Ventures's product category is Healthcare Venture Capital. Its primary akta.pro industry code is FSANAAAB, Early-Stage Venture Capital (Series A/B), with a secondary code of FSANAAAD, Sector-Focused Venture Capital (Vertical Specialists). Its NAICS code is 5259 and its SIC code is 6199.