上海碧云天生物技术有限公司

What 上海碧云天生物技术有限公司 does

上海碧云天生物技术有限公司 (Beyotime Biotechnology) is a privately-held Shanghai-based biotechnology company founded in 2001 that develops, manufactures, and sells life-science research reagents and laboratory services to academic and industrial customers in China. The company's product portfolio spans recombinant proteins, antibodies, cell biology reagents, molecular biology reagents, biochemical reagents, laboratory instruments, and consumables, organized under sub-brands including BeyoAb™, PerfectPro™, BeyoEquip™, BeyoGold™, BeyoMag™, BeyoShaker™, and BeyoVortex™. Core technical capabilities include recombinant protein production using Pichia pastoris expression systems, proprietary magnetic bead purification technologies (e.g., BeyoMag™ Pepsin Magnetic Agarose Beads), and Animal Origin-Free (AOF) recombinant enzymes.

The company operates three revenue streams: (1) direct sales of reagent products at unit pricing in RMB (ranging from tens to thousands of RMB per item), (2) technical services including gene synthesis, antibody customization, Western Blot/ELISA, CRISPR/Cas9, and virus packaging, and (3) an online plasmid platform providing access to various plasmid constructs. Distribution is exclusively domestic (China) via direct-to-customer channels including beyotime.com e-commerce, WeChat mini-program mall, phone/QQ ordering, and email. The company has established cooperative laboratory partnerships with 10 major Chinese universities including Tongji, USTC, Sun Yat-sen, HUST, and Wuhan University.

Customers span academic research institutions (primary), pharmaceutical and biotechnology companies (primary), and hospital/clinical laboratories (secondary). Products are cited in over 20,000 scientific publications, indicating significant adoption in the Chinese research community. The company operates as a non-listed, apparently founder-owned enterprise with no disclosed external funding, no patents listed, and no M&A activity. No AI/ML capabilities are evident in the product portfolio or technology stack.

Name

上海碧云天生物技术有限公司

Legal name

上海碧云天生物技术有限公司

Website

https://beyotime.com

Company type

Private

Founded year

2001

Operating status

Operating

Headcount range

11–50 employees

Short description

Shanghai-based Beyotime Biotechnology is a privately-held life-science reagent manufacturer founded in 2001, selling recombinant proteins, antibodies, cell/molecular biology reagents, instruments, and consumables to Chinese academic institutions, pharmaceutical companies, and biotech firms through direct e-commerce and service channels.

Ownership category

akta.pro rank

Product category

Life Science Research Reagents

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714), Scientific Research and Development Services (5417), Analytical Laboratory Instrument Manufacturing (334516)

SIC

Biological Products, (No Disgnostic Substances) (2836), Laboratory Analytical Instruments (3826)

akta.pro primary industry

Raw Materials & Critical Reagents Supply (Media/Resins/Cytokines) (HLAGAGAI)

akta.pro secondary industries

Bioprocess Consumables & Reagents (resins, membranes, media components, buffers) (HLAAAJAI), Microscopy, Imaging & Flow Cytometry Instruments (HLAGAIAE)

Keywords

• Biotechnology reagents
• Recombinant proteins
• Antibody products
• Cell biology reagents
• Laboratory instruments

Headquarters

HQ city

Shanghai

HQ country

China

HQ region

Asia

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Supply Chain, Operations, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Biototechnology Reagent Sales: Direct sales of recombinant proteins, antibodies, cell biology products, molecular biology reagents, biochemical reagents, instruments, and consumables through their e-commerce platform and direct sales team. Products include various sizes with corresponding pricing.
2. Technical Services: Provides comprehensive biotechnology services including gene synthesis, plasmid construction, real-time PCR, high-throughput sequencing, peptide synthesis, protein expression and purification, antibody customization, Western Blot, ELISA, immunofluorescence, immunohistochemistry, Co-IP, proteomics, biochemical detection, SPR detection, cell proliferation, apoptosis, migration/invasion assays, flow cytometry, CRISPR/Cas9, virus packaging, and more.
3. Plasmid Platform Services: Online plasmid platform providing access to various plasmid constructs including bacterial strains, yeast-related, virus construction, competent cells, prokaryotic/eukaryotic vectors, reporter gene plasmids, gene expression plasmids, fluorescent probe plasmids, CRISPR editing plasmids, and more.

Pricing tiers

Go-to-market motion1 record

Distribution channels5 records

Marketing channels9 records

Core offering

上海碧云天生物技术有限公司 develops, manufactures, and sells life science research reagents — including recombinant proteins, antibodies, enzymes, fluorescent dyes, cell biology reagents, nucleic acid reagents, and biochemical reagents — along with laboratory instruments (electrophoresis, imaging, mixers, temperature control), consumables (cell culture plastics), and a catalog of branded sub-product lines (BeyoAb™, PerfectPro™, BeyoEquip™, BeyoGold™, BeyoMag™, BeyoShaker™, BeyoVortex™). The company also operates an online plasmid platform and offers custom technical services such as gene synthesis, peptide synthesis, antibody customization, sequencing, CRISPR/Cas9 work, and lentivirus packaging for academic and industrial life science researchers.

Product overview

上海碧云天生物技术有限公司 (Beyotime Biotechnology) is a biotechnology company offering a comprehensive portfolio of research reagents, instruments, and technical services. The product portfolio includes multiple sub-brands: BeyoAb™ (antibodies), PerfectPro™ (recombinant proteins), BeyoEquip™ (laboratory instruments), BeyoGold™ (consumables), and BeyoMag™ (magnetic beads for purification). The company provides reagents across nucleic acid research, peptides/proteins, cell biology, signal transduction, and antibodies, as well as technical services through its plasmid platform and biotech service platform. Product categories span from basic reagents (enzymes, buffers, biochemical reagents) to specialized items like CRISPR/Cas9 tools, viral packaging services, and comprehensive research services including sequencing, proteomics, and animal efficacy studies.

Differentiator

Problem solved

Functional benefit

Brands

• BeyoGold™: Premium laboratory consumables brand including TC-enhanced cell culture products
• BeyoMag™
• BeyoEquip™
• BeyoAb™
• BeyoVortex™
• BeyoShaker™
• PerfectPro™

Products and services

• BeyoAb™ Antibody Products Branded line of antibodies — primary, secondary (HRP, Biotin, ALP, fluorescent), internal reference, tag, and organelle marker antibodies — for life science research use.
• PerfectPro™ Recombinant Proteins Branded line of recombinant proteins — cytokines, chemokines, hormones, and enzymes — produced using Beyotime's proprietary expression systems.
• BeyoEquip™ Laboratory Instruments Branded line of laboratory instruments spanning sample processing, electrophoresis, imaging, mixing, temperature control, separation, safety, cleaning, and cold storage.
• BeyoGold™ Cell Culture Consumables Branded line of cell culture consumables — TC-enhanced culture plates, bottles, cryopreservation tubes, serological pipettes, and serum bottles.
• BeyoMag™ Magnetic Beads Branded line of magnetic beads for protein and antibody purification — Protein A, Protein G, Protein A/G, His-tag, GST-tag, and pepsin magnetic agarose beads.
• Recombinant Proteolytic Enzymes Recombinant proteolytic enzymes — including recombinant human ACE2, BACE1, IdeZ Protease, trypsin, carboxypeptidase B, Kex2 protease, aprotinin, enterokinase, and Proteinase K — used in protein research and bioprocessing.
• Recombinant Protein A/G/L Recombinant Protein A, Protein G, Protein L, and combinations (Protein A/G, Protein A/G/L) in various tagged forms for antibody purification workflows.
• Recombinant Hormones Recombinant hormones — human growth hormone (GH), human insulin, PTH variants, murine/rat prolactin, and leptin — for endocrinology and metabolic research.
• Hoechst Fluorescent Dyes Fluorescent dyes including Hoechst 33258, Hoechst 33342, and related staining solutions for cell nucleus staining and apoptosis detection.
• Biotech Service Platform (技术服务平台) Custom technical services covering primer/RNA/gene synthesis, plasmid construction, qPCR, high-throughput sequencing, peptide synthesis, protein expression and purification, antibody customization, Western Blot, ELISA, immunofluorescence, immunohistochemistry, CRISPR/Cas9 gene editing, and lentivirus packaging for academic and industrial researchers.
• Plasmid Platform (质粒平台) Online resource providing access to bacterial strains, yeast-related plasmids, virus construction reagents, competent cells, prokaryotic and eukaryotic vectors, reporter gene plasmids, gene expression plasmids, fluorescent probe plasmids, and CRISPR editing plasmids.

Quantifiable outcome

• Products cited in over 20,000 scientific publications
• +2 more outcomes

Named customers10 records

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

Ten partnerships are on record, tiered core.

• Tongji UniversitycoreStrategic or Co-development PartnerCooperative laboratory partnership with Tongji University for joint research and product development. Beyotime provides biotechnology reagents and services while university provides research expertise and collaboration opportunities.
• University of Science and Technology of China (USTC)coreStrategic or Co-development PartnerCooperative laboratory partnership with USTC for collaborative biotechnology research. The partnership supports academic research while providing real-world applications for Beyotime products.
• Sun Yat-sen UniversitycoreStrategic or Co-development PartnerEstablished cooperative laboratory with Sun Yat-sen University for mutual research collaboration and product development.
• Jinan UniversitycoreStrategic or Co-development PartnerCooperative laboratory partnership supporting biotechnology research collaboration.
• Huazhong University of Science and TechnologycoreStrategic or Co-development PartnerJoint laboratory collaboration for life science research and reagent development.
• Wuhan UniversitycoreStrategic or Co-development PartnerCooperative laboratory partnership for biotechnology research collaboration.
• University of Electronic Science and Technology of China (UESTC)coreStrategic or Co-development PartnerCooperative laboratory partnership supporting interdisciplinary research.
• West China Medical Center (Huaxi)coreStrategic or Co-development PartnerCooperative laboratory with West China Hospital for medical biotechnology research.
• Hunan UniversitycoreStrategic or Co-development PartnerCooperative laboratory partnership for biotechnology research.
• Nanjing Agricultural UniversitycoreStrategic or Co-development PartnerCooperative laboratory partnership for agricultural biotechnology research.

Scale indicators4 records

Recent moves6 records

Expansion highlights5 records

Broad incumbents

• GenScript Biotech: China-founded but globally scaled life science services and reagent provider with gene synthesis, peptide, protein, and antibody offerings — directly overlapping Beyotime's biotech service platform and plasmid platform offerings.
• Bio-Rad Laboratories: Established life science research tools company with overlapping offerings in protein purification (Bio-Scale, NGC chromatography), reagents, and lab instruments — competing with Beyotime's BeyoMag™ and BeyoEquip™ lines.
• Thermo Fisher Scientific: Global life science tools giant whose brands (Invitrogen, Thermo Scientific, Gibco, Pierce) compete head-on with Beyotime across recombinant proteins, antibodies, cell culture, and instruments, and which is actively localizing in China.
• Merck KGaA (Sigma-Aldrich / MilliporeSigma): Global incumbent in life science reagents and biochemicals. Beyotime's catalog (antibodies, recombinant proteins, biochemical reagents) sits squarely in Sigma-Aldrich's historic core categories.
• Tocris Bioscience (Bio-Techne): Specialty supplier of high-purity reagents (inhibitors, agonists, antibodies) for life science research under Bio-Techne. Competitor in Beyotime's signal transduction, inhibitor/activator, and neuroscience research reagent categories.

Emerging players

• MedChemExpress: Fast-growing China-origin life science chemical and reagent supplier with strong direct-to-researcher e-commerce model comparable to Beyotime's online platform. Overlaps in inhibitors/activators, recombinant proteins, and bioactive molecules.

Direct peers

• ABclonal Technology: Wuhan-based Chinese antibody and recombinant protein supplier with proprietary rabbit monoclonal antibody technology. Competes with Beyotime's BeyoAb™ antibody line and PerfectPro™ recombinant protein portfolio in China and globally.
• Proteintech: Wuhan-based antibody manufacturer with strong researcher-citation footprint (similar to Beyotime's 20,000+ citations), focused on antibodies and recombinant proteins for academic and industrial customers.
• Sangon Biotech: Shanghai-based Chinese life science reagent manufacturer offering nucleic acid, protein, and cell biology products with similar B2B/B2C direct-to-researcher distribution. Directly competes with Beyotime across multiple reagent categories.
• Yeasen Biotechnology: Shanghai-based Chinese reagent supplier with comparable portfolio of recombinant proteins, enzymes, antibodies, and cell biology reagents sold directly to academic and industrial researchers. Closest direct head-to-head competitor to Beyotime in the domestic Chinese market.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks5 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/%E4%B8%8A%E6%B5%B7%E7%A2%A7%E4%BA%91%E5%A4%A9%E7%94%9F%E7%89%A9%E6%8A%80%E6%9C%AF%E6%9C%89%E9%99%90%E5%85%AC%E5%8F%B8

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about 上海碧云天生物技术有限公司