Laboratório Cirúrgico de Pesquisa Cardiovascular (LIM-11), Instituto do Coração (Incor), HCFMUSP

What Laboratório Cirúrgico de Pesquisa Cardiovascular (LIM-11), Instituto do Coração (Incor), HCFMUSP does

LIM-11 (Laboratório Cirúrgico de Pesquisa Cardiovascular) is one of 62 Laboratory Investigation Units (LIMs) operating within the Hospital das Clínicas da FMUSP (HCFMUSP) complex at the University of São Paulo, physically housed at the Instituto do Coração (InCor) in São Paulo, Brazil. Established in 1975 as part of the LIM network and formally incorporated into HCFMUSP's administrative structure in 1977 under Decree 9.720/77, LIM-11 conducts cardiovascular surgical research and physiopathology of circulation, including clinical studies, surgical technique development, and translational cardiovascular investigation. It operates not as a commercial entity but as a public academic research unit dependent on Brazilian federal and state research agencies (FAPESP, CNPq, CAPES, FINEP).

The unit shares infrastructure across the LIM network including the PREMiUM multi-user equipment network, GRID HCFMUSP high-performance computing system for large-scale data processing across omics sciences and medical imaging, and SELA large-scale DNA sequencing capabilities. LIM-11 serves academic researchers, graduate and postdoctoral students, and indirectly serves patients of HCFMUSP/InCor requiring specialized cardiovascular care. Distribution of research outputs occurs through scientific publication, participation in the PREMiUM equipment network, visiting researcher programs, and international cooperation agreements.

The business model is non-commercial: LIM-11 is funded entirely through government research grants and scholarships, with personnel hired through public concursos (HCFMUSP) or selection processes via the Fundação Faculdade de Medicina (FFM). There are no commercial pricing models, no customers in the traditional sense, and no disclosed revenue. Marketing and outreach occur through the institutional website (limhc.fm.usp.br), YouTube (@LIM_HCFMUSP), Instagram (@lim.hcfmusp), FAPESP News Agency, and monthly scientific seminars.

Name

Laboratório Cirúrgico de Pesquisa Cardiovascular (LIM-11), Instituto do Coração (Incor), HCFMUSP

Legal name

Laboratórios de Investigação Médica do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

Website

https://limhc.fm.usp.br

Company type

Private

Founded year

1975

Operating status

Operating

Headcount range

11–50 employees

Short description

LIM-11 is a public academic research laboratory at InCor/HCFMUSP in São Paulo conducting cardiovascular surgical research. It operates as one of 62 government-funded LIM units, serving academic researchers, graduate students, and indirectly HCFMUSP patients, with no commercial revenue model.

Ownership category

akta.pro rank

Product category

Cardiovascular Research Services

NAICS

Medical Laboratories (621511), Other Scientific and Technical Consulting Services (54169)

SIC

Services-Commercial Physical & Biological Research (8731), Services-Medical Laboratories (8071)

akta.pro primary industry

Laboratory Informatics & Reporting (LIMS/ELR) Public Health Networks (HLAJAIAN)

Keywords

• Cardiovascular surgical research
• Medical investigation laboratory
• Clinical research services
• Cardiovascular disease research
• Translational medicine research

Headquarters

HQ city

São Paulo

HQ country

Brazil

HQ region

Latin America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Technology or R&D, Infrastructure, Operations

Distribution channels1 record

Marketing channels5 records

Core offering

LIM-11 is one of 62 Medical Investigation Laboratories (LIMs) at Hospital das Clínicas da FMUSP (HCFMUSP) in São Paulo, Brazil. Operating within the Instituto do Coração (InCor), it conducts cardiovascular surgical and physiopathological research, supports graduate training, and develops innovative diagnostic, therapeutic, and preventive approaches for cardiovascular diseases. The laboratory leverages shared infrastructure including the PREMiUM multi-user equipment network, GRID high-performance computing, and SELA large-scale DNA sequencing capabilities to translate bench research into bedside clinical applications.

Differentiator

Problem solved

Functional benefit

Products and services

• PREMiUM Multi-user Equipment Network (Rede de Equipamentos Multiusuários) Shared research infrastructure network managed by the LIM Executive Directorate that provides authorized researchers with access to specialized multi-user equipment across all 62 LIMs of HCFMUSP for cardiovascular and medical research projects.
• Programa de Especialização "Lato Sensu" Specialization (lato sensu) training program for medical professionals and researchers at LIM-11 / HCFMUSP, funded through scholarships (bolsas) provided by the São Paulo state health secretary (SES-SP) and research agencies.
• GRID HCFMUSP High-Performance Computing Services High-performance computing grid service for large-scale scientific data processing supporting omics sciences (genomics, proteomics, transcriptomics), medical imaging, and AI applications in cardiovascular and biomedical research.
• Scientific Seminars and Workshops Monthly scientific seminars organized by the LIM Scientific Commission and Executive Directorate featuring diverse research topics, plus targeted workshops such as the Young Researcher Workshop, supporting knowledge dissemination in cardiovascular and health sciences.

Quantifiable outcome

• Producing over 1,600 scientific articles annually in indexed journals
• +1 more outcomes

Segments4 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

Four partnerships are on record, tiered core and major.

• Caja Costarricense de Seguro Social (CCSS)coreStrategic or Co-development Partner · 1 March 2026Technical cooperation agreement between HCFMUSP and CCSS implemented through HCX FMUSP international programs. Delegation from Costa Rica visited to learn LIM research management model. Part of broader healthcare cooperation between Brazil and Costa Rica.
• London School of Hygiene and Tropical Medicine (LSHTM)coreStrategic or Co-development Partner · 1 August 2024STI-Net Workshop Brazil UK organized with LSHTM to review data on sexually transmissible infections and antimicrobial resistance. Led by LIM 49 (Protozoology, Bacteriology and Antimicrobial Resistance). Multicenter study supported by CNPq.
• Ireland Research Council (IRC)majorStrategic or Co-development PartnerFive-year cooperation agreement signed during FAPESP Week London to promote basic scientific research cooperation between Ireland and São Paulo state, with focus on Horizon 2020 and Horizon Europe applications.
• Global Alliance for Chronic Diseases (GACD)majorStrategic or Co-development PartnerInternational association of research funding agencies for chronic non-communicable diseases. Joint call with FAPESP for cancer prevention research projects in São Paulo state.

Scale indicators8 records

Recent moves7 records

Expansion highlights3 records

Direct peers

• Texas Heart Institute: Independent cardiovascular research institute focused on heart disease research, education, and translational care. Most comparable to LIM-11 as a specialized cardiovascular research unit operating alongside clinical care, with similar mission of advancing cardiac surgery and treatment.
• German Heart Institute Berlin (Deutsches Herzzentrum Berlin): Specialized cardiovascular hospital and research center affiliated with Charité. Comparable to LIM-11 in being a dedicated heart institute combining cardiovascular surgical research with clinical practice and academic training in a single integrated structure.
• Imperial College London National Heart and Lung Institute: Academic cardiovascular and respiratory research institute embedded within Imperial College London. Comparable to LIM-11 as a hospital- and university-affiliated cardiovascular research unit producing high-impact publications and training clinical researchers.
• Erasmus MC Thorax Center: Cardiovascular and pulmonary research and clinical center within Erasmus University Medical Center Rotterdam. Directly comparable to LIM-11/InCor as an academic cardiovascular research and clinical care hub integrated with a major teaching hospital.
• Montreal Heart Institute (Institut de Cardiologie de Montréal): Specialized cardiovascular hospital and research center affiliated with Université de Montréal. Directly comparable to LIM-11/InCor as a hospital-integrated cardiovascular research institute combining clinical cardiology with bench research and training.

Regional players

• Hospital Israelita Albert Einstein: Leading Brazilian private hospital with active clinical research programs across multiple specialties including cardiovascular. Comparable as a Brazilian hospital-based research organization, though operating as a private institution rather than a public university hospital like LIM-11's parent HCFMUSP.
• Butantan Institute: Brazilian public research institute focused on vaccines, biopharmaceuticals, and biomedical research. Comparable to LIM-11 as a São Paulo-based public research institution with significant academic output and government funding, though specialized in immunology and vaccines rather than cardiovascular.
• Oswaldo Cruz Foundation (Fiocruz): Brazilian public health research institution under the Ministry of Health, with extensive research output and graduate training programs. Comparable to LIM-11 as a publicly funded Brazilian research institution with similar academic publishing scale and international collaboration patterns, though broader in scope (infectious disease, public health).

Emerging players

• London School of Hygiene & Tropical Medicine: Internationally ranked public health and tropical medicine research and graduate institution with which LIMs have an active STI-Net collaboration. Comparable to LIM-11 as an academic public-health research organization partnering on international multicenter studies.

Broad incumbents

• Cleveland Clinic Lerner Research Institute: Large multi-specialty medical research institute within Cleveland Clinic, including significant cardiovascular and cardiothoracic research. Comparable to LIM-11's broader HCFMUSP research umbrella as a hospital-embedded research enterprise, though broader in scope than LIM-11's cardiovascular focus.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks5 records

Key highlights6 records

Customer concentration

• YouTubeyoutube.com/@LIM_HCFMUSP
• Instagraminstagram.com/lim.hcfmusp
• LinkedInlinkedin.com/company/laborat%C3%B3rio-cir%C3%BArgico-de-pesquisa-cardiovascular-lim-11-instituto-do-cora%C3%A7%C3%A3o-incor-hospital-da

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

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M&A

Investments

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Frequently asked questions about Laboratório Cirúrgico de Pesquisa Cardiovascular (LIM-11), Instituto do Coração (Incor), HCFMUSP