Hôpital Bretonneau

What Hôpital Bretonneau does

The Centre Régional de Pharmacovigilance Centre-Val de Loire (CRPV Tours) is the officially designated regional pharmacovigilance center for the Centre-Val de Loire region, operating as a public health function within the Service de Pharmacologie clinique of CHRU Tours in Tours, France. Its mandate covers six departments (37, 41, 45, 18, 28, 36) and serves two principal segments: healthcare professionals (physicians, pharmacists, nurses, dentists, midwives) who require expert guidance on prescribing and adverse event reporting, and patients seeking to report adverse drug reactions or obtain medication safety information. Core services include adverse drug reaction reporting and analysis, personalized prescription assistance, medication risk assessment during pregnancy and breastfeeding, medication error reporting, and systematic dissemination of ANSM drug safety alerts and information bulletins.

The center operates an online portal (pharmacovigilance-tours.fr) built on the Contao content management system, providing structured web-based forms for adverse event declarations, specialized pregnancy and breastfeeding consultation questionnaires, and medication error reporting forms that forward signals to ANSM for regulatory action. It publishes periodic PDF information bulletins (most recently Bulletin N°129 covering July-December 2025) and maintains an email newsletter subscription channel. Technical operations are supported by web agency ADDICTIC and hosted on Infomaniak infrastructure in Geneva, with GDPR-compliant data processing overseen by the CHRU de Tours Data Protection Officer.

CRPV Tours is funded through French institutional public health mechanisms (ANSM, Ministry of Health, CHRU Tours) under ANSM oversight, with all services provided free of charge to professionals and patients. The center participates in the national Réseau des CRPV and the European pharmacovigilance network coordinated by EMA, contributing adverse event data to the Base Nationale de PharmacoVigilance. Distribution occurs through institutional channels including the online portal, telephone, fax, email, and postal mail, with reach extended via CHRU Tours and the GHT Touraine Val de Loire territorial hospital grouping. The director of publication is Anne-Pierre Jonville-Bera.

Name

Hôpital Bretonneau

Legal name

Service de Pharmacologie clinique - CHRU TOURS

Website

https://pharmacovigilance-tours.fr

Company type

Private

Operating status

Operating

Headcount range

51–100 employees

Short description

CRPV Centre-Val de Loire is a publicly funded regional pharmacovigilance center within CHRU Tours, France, providing adverse drug reaction reporting, prescription assistance, pregnancy medication safety analysis, and ANSM alert dissemination to healthcare professionals and patients across six Centre-Val de Loire departments.

Ownership category

akta.pro rank

Product category

Pharmacovigilance Services

SIC

Services-Health Services (8000)

akta.pro primary industry

Pharmacovigilance, Risk Management & Medical Affairs CROs (HLAGAAAH)

akta.pro secondary industry

Safety & Medical Contact Centers (AE Intake/Call Centers) (HLAGALAI)

Keywords

• Pharmacovigilance services
• Adverse drug reaction reporting
• Medication safety monitoring
• Prescription risk assessment
• Medication error analysis

Headquarters

HQ city

Tours

HQ country

France

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Infrastructure, Technology or R&D

Revenue model

1. Public institutional funding: As a designated regional pharmacovigilance center (CRPV) under the French public health system, the organization is funded through institutional public health mechanisms (ANSM, Ministry of Health, CHRU Tours). No commercial revenue model applies.

Go-to-market motion1 record

Distribution channels3 records

Marketing channels5 records

Core offering

CRPV Centre-Val de Loire is a designated regional pharmacovigilance center providing adverse drug reaction reporting, personalized prescription assistance, medication risk analysis during pregnancy and breastfeeding, medication error reporting, and dissemination of ANSM drug safety alerts for healthcare professionals and patients across six departments of the Centre-Val de Loire region. It operates within the Service de Pharmacologie clinique of CHRU Tours.

Product overview

The CRPV Tours is a regional pharmacovigilance center serving the Centre-Val de Loire region (departments 37, 41, 45, 18, 28, 36). It provides a comprehensive portfolio of pharmacovigilance services including adverse drug reaction reporting (for both professionals and patients), personalized prescription assistance, medication risk analysis during pregnancy and breastfeeding, and medication error reporting. The center disseminates ANSM alerts and publishes periodic information bulletins to keep healthcare professionals informed about drug safety.

Differentiator

Problem solved

Functional benefit

Products and services

• Déclaration d'effets indésirables médicamenteux Service for healthcare professionals and patients to report adverse drug reactions to the regional pharmacovigilance center, which then forwards significant signals to ANSM for national and European regulatory evaluation.
• Aide à la prescription médicamenteuse Personalized prescription assistance for physicians and healthcare professionals in the Centre-Val de Loire region regarding medication safety, including guidance for special populations and complex prescribing situations.
• Analyse des risques médicamenteux pendant la grossesse et l'allaitement Risk analysis service for medication use during pregnancy and breastfeeding, including pregnancy exposure declarations, targeted at healthcare professionals and patients in the Centre-Val de Loire region.
• Signalement d'erreurs médicamenteuses Reporting and analysis service for medication errors that cause adverse effects or stem from product design, labeling, or information issues, with significant signals forwarded to ANSM for regulatory action.
• Alertes ANSM Dissemination of drug safety alerts issued by ANSM (French National Agency for Medicines and Health Products Safety) to healthcare professionals in the Centre-Val de Loire region, contextualized for the local audience.
• Bulletins d'informations en pharmacovigilance Periodic information bulletins (e.g., N° 129, N° 128) providing updates on pharmacovigilance topics, published in PDF format and available for download through the CRPV Tours website.
• Formulaire de déclaration en ligne Online structured form for healthcare professionals to declare adverse drug reactions, including patient information, drug details, and severity classification, enabling systematic web-based reporting to the regional pharmacovigilance center.

Segments2 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

Nine partnerships are on record, tiered core and minor.

• ANSM (Agence nationale de sécurité du médicament et des produits de santé)coreStrategic or Co-development PartnerThe CRPV Centre-Val de Loire operates as a designated regional pharmacovigilance center under ANSM oversight. The center collects adverse drug event reports and forwards significant signals to ANSM for national and European regulatory evaluation. ANSM alerts are relayed to regional healthcare professionals through the center.
• EMA (European Medicines Agency)coreStrategic or Co-development PartnerCRPV France participates in the European pharmacovigilance network coordinated by EMA. Adverse event data from the national database contributes to European drug safety evaluations. The center operates within the EU regulatory framework governed by EMA guidelines.
• Réseau des CRPV (National CRPV Network)coreStrategic or Co-development PartnerThe CRPV Centre-Val de Loire participates in the national network of Regional Pharmacovigilance Centers (Réseau des CRPV), facilitating knowledge sharing, coordinated signal detection, and collaborative pharmaco-epidemiological studies across France.
• HAS (Haute Autorité de Santé)minorOthersHAS is referenced as a linked resource on the CRPV website, providing authoritative guidance on drug efficacy and safety assessments that complement the center's pharmacovigilance activities.
• ADDICTICminorImplementation/ SI/ Consulting PartnerADDICTIC designed and developed the CRPV Tours website (pharmacovigilance-tours.fr), operating as the website's publisher and technical service provider. Contact: 40 rue de l'aéroport, 37100 Tours.
• Infomaniak Network SAminorImplementation/ SI/ Consulting PartnerInfomaniak provides web hosting services for the CRPV Tours website through its Swiss-based infrastructure (Rue Eugène Marziano 25, 1227 Les Acacias, Geneva, Switzerland), operating as a data processor under the center's instructions.
• DPO (Délégué à la Protection des Données) - CHRU de ToursminorOthersThe Data Protection Officer for CHRU de Tours oversees compliance with GDPR and French data protection law (Loi Informatique et Libertés) for all data processed by the CRPV, including adverse event reports and patient health data. Contact: [email protected].
• CHRU de Tours (Centre Hospitalier Régional Universitaire de Tours)coreStrategic or Co-development PartnerThe CRPV Centre-Val de Loire is organizationally embedded within the Service de Pharmacologie clinique of CHRU Tours. The hospital provides institutional hosting, staffing, and administrative infrastructure. Data from CHRU patient care may feed into the pharmacovigilance database via the clinical data warehouse (Entrepôt de données cliniques, CNIL authorization 12/11/2019).
• GHT Touraine Val de Loire (Groupement Hospitalier de Territoire)coreStrategic or Co-development PartnerThe CRPV operates within the GHT Touraine Val de Loire territorial hospital group, facilitating data sharing and care pathway coordination among member healthcare establishments for pharmacovigilance and patient safety purposes.

Scale indicators1 record

Recent moves5 records

Expansion highlights3 records

Broad incumbents

• IQVIA Pharmacovigilance Services: Commercial global CRO offering end-to-end pharmacovigilance, drug safety, and risk management services to pharmaceutical sponsors. Operates in the same functional domain as CRPV Tours (AE processing, signal detection, regulatory reporting) but for commercial clients rather than as a public regulator.
• ANSM (Agence nationale de sécurité du médicament): The French national medicines regulator that oversees and designates regional CRPVs including CRPV Tours. Operates upstream of the regional centers, aggregating signals and issuing national drug safety alerts that flow back through the CRPV network.
• ICON plc (PRA Health Sciences / ICON Pharmacovigilance): Global CRO providing commercial pharmacovigilance, post-marketing safety, and risk management services. Comparable in functional domain (AE intake, ICSRs, signal detection) but operates under a commercial, sponsor-funded model versus CRPV's public-regulator model.
• EMA (European Medicines Agency): European-level pharmacovigilance coordinator that integrates national AE databases (including those populated via the French CRPV network) for EU-wide drug safety evaluations. Operates at a broader geographic scope than any single CRPV.

Direct peers

• CRPV Lyon (Centre Régional de Pharmacovigilance de Lyon): Another ANSM-designated regional pharmacovigilance center operating under the same national CRPV network, with an identical mandate covering adverse drug reaction reporting, medication error analysis, and prescription assistance for healthcare professionals in its assigned region. Directly comparable in scope, services, and regulatory positioning.
• CRPV Paris (Centre Régional de Pharmacovigilance de Paris): Paris-based regional pharmacovigilance center serving the Île-de-France region under the same CRPV network. Operates the same ANSM-mandated services (AE intake, medication error reporting, pregnancy/breastfeeding advice) and participates in the same EMA-coordinated European pharmacovigilance network.

Others

• CHRU de Tours (Centre Hospitalier Régional Universitaire de Tours): Parent institution that hosts CRPV Tours within its Service de Pharmacologie clinique. Provides institutional infrastructure, staffing, and the clinical data warehouse (CNIL authorization 12/11/2019) that underpins pharmacovigilance operations.

Emerging players

• ArisGlobal (LifeSphere Safety): Technology vendor providing pharmacovigilance and drug safety software platforms (case intake, ICSR management, signal detection). Comparable in the AE intake and case management functionality, but operating as a commercial SaaS vendor rather than a public health service provider.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks5 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/h%C3%B4pital-bretonneau

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Hôpital Bretonneau