The Alliance for Longevity Initiatives
The Alliance for Longevity Initiatives (A4LI) is the first U.S. 501(c)(4) nonprofit dedicated exclusively to advancing longevity science through public policy advocacy, serving biotech innovators, researchers, and Congressional policymakers since 2022.
- Company typePrivate
- Founded2022
- HeadquartersVirginia, El Salvador
- Headcount1–10
- GTM typeB2B
- OfferingServices
What The Alliance for Longevity Initiatives does
The Alliance for Longevity Initiatives (A4LI) is a U.S. 501(c)(4) nonprofit advocacy organization founded in 2022 by Dylan V. Livingston. It is the first organization of its kind in the United States dedicated exclusively to advancing longevity science through public policy. Its mission centers on mitigating age-related diseases (cancer, cardiovascular disease, Alzheimer's) by connecting scientific research with legislative action, with three core advocacy pillars: increasing federal funding for aging biology research (currently less than 1% of the $48.7 billion NIH budget), establishing clear FDA standards to streamline approval of longevity medicines, and advocating for a national healthy life expectancy goal.
A4LI's product surface consists of advocacy initiatives rather than technology products. Core programs include the annual H-SPAN Summit D.C. (its flagship convening event, entering its third year in 2026 in partnership with Georgetown University Medical Center), the bipartisan Longevity Science Caucus in Congress (co-founded by A4LI, re-launched April 2025 with six named Representatives), the H-SPAN Podcast and Scientific Spotlights media properties, a membership program, a Discount Marketplace offering member benefits from longevity product sponsors, and a Letters to Congress advocacy tool. The organization facilitated more than 70 meetings between advocates and Congressional members in 2025.
The business model is a nonprofit advocacy revenue stack with three streams: (1) recurring annual membership fees (pricing undisclosed), (2) corporate sponsorships from longevity biotech companies (disclosed sponsors include Gordian, Agelessrx, Minicircle, Optispan, 100 Plus Capital, Retro Biosciences, and BioAge Labs), and (3) individual donations via the organization's website. The go-to-market motion is community-led, mobilizing members for direct legislative advocacy through petitions, letters, volunteer opportunities, and events. Primary customer segments are longevity biotech investors and innovators, U.S. Congressional members and staff (particularly the bipartisan Longevity Science Caucus), academics and researchers in aging biology, and aligned non-profits. A4LI is founder-controlled, operating with a lean leadership team (founder/president, chair, VP of communications, director of operations, and operations coordinator) plus a scientific advisory board.
The Alliance for Longevity Initiatives firmographics
Firmographics- Name
- The Alliance for Longevity Initiatives
- Legal name
- The Alliance for Longevity Initiatives
- Website
- https://a4li.org
- Company type
- Private
- Founded year
- 2022
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Short description
- The Alliance for Longevity Initiatives (A4LI) is the first U.S. 501(c)(4) nonprofit dedicated exclusively to advancing longevity science through public policy advocacy, serving biotech innovators, researchers, and Congressional policymakers since 2022.
- Ownership category
- akta.pro rank
The Alliance for Longevity Initiatives industry classification
Industry- Product category
- Longevity Policy Advocacy
- NAICS
- Civic and Social Organizations (8134), Voluntary Health Organizations (813212), Religious, Grantmaking, Civic, Professional, and Similar Organizations (813)
- SIC
- Services-Social Services (8300), Services-Membership Organizations (8600)
- akta.pro primary industry
- Elder Services & Aging Support (BPAGAEAF)
Keywords
Where The Alliance for Longevity Initiatives is headquartered
LocationHeadquarters
- HQ city
- Virginia
- HQ country
- El Salvador
- HQ region
- Latin America
Markets served
The Alliance for Longevity Initiatives business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Operations, Marketing or Sales, Others
Revenue model
- Membership fees: A4LI generates revenue through membership fees, offering exclusive access to events, expert discussions, longevity research updates, and discounts on longevity conferences and products. Members help amplify the organization's mission and shape the future of longevity policy.
- Sponsorships: Corporate sponsors from the longevity biotech sector support A4LI's advocacy efforts. Sponsors include companies like Gordian, Agelessrx, Minicircle, Optispan, 100 Plus Capital, RetroBio, and BioAge.
- Donations: Individual donations from supporters of longevity science advocacy. The organization accepts donations through various channels including their website donation portal.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Subscription | Annual | Individual Membership with access to events, expert discussions, research updates, and member discounts |
Go-to-market motion1 record
Distribution channels1 record
Marketing channels7 records
The Alliance for Longevity Initiatives product offering
Product offeringCore offering
A4LI is a 501(c)(4) nonprofit advocacy organization that drives legislation and policy aimed at extending healthy human lifespan. It operates through membership programs, corporate sponsorships, and individual donations to convene lawmakers, biotech innovators, researchers, and supporters around policy goals including increased federal funding for aging research, FDA standards for longevity medicines, and national healthy life expectancy goals. Its core deliverables include the annual H-SPAN Summit D.C., advocacy campaigns, the bipartisan Longevity Science Caucus, and member benefits such as the discount marketplace.
Product overview
The Alliance for Longevity Initiatives (A4LI) is a 501(c)(4) nonprofit policy and advocacy organization rather than a technology product company. Its offerings consist of advocacy programs, membership services, educational content, and events aimed at advancing legislation and policies for extending healthy human lifespan. The core programs include the H-SPAN Podcast and Scientific Spotlights for scientific communication; the annual H-SPAN Summit D.C. as the premier advocacy event; the bipartisan Longevity Science Caucus for congressional engagement; A4LI Membership providing exclusive access and benefits; and a Discount Marketplace offering deals on longevity-related products and services. These offerings work together to advance A4LI's mission of accelerating equitable access to next-generation longevity therapies through political and social action.
Differentiator
Problem solved
Functional benefit
Products and services
- A4LI Membership Program Annual membership program for individuals aligned with longevity science policy, offering exclusive access to events, expert discussions, updates on cutting-edge longevity research, and discounts on longevity conferences and products.
- H-SPAN Summit D.C. Annual flagship event in Washington, D.C. bringing together leaders, advocates, and innovators to advance legislative initiatives promoting healthier human lifespan.
- Corporate Sponsorship Program Sponsorship program for longevity biotech companies to support A4LI's advocacy efforts in exchange for visibility and alignment with longevity science policy initiatives.
Quantifiable outcome
- Facilitated over 70 meetings between advocates and Congressional members in 2025
- +3 more outcomes
Companies that use The Alliance for Longevity Initiatives
Customer profileNamed customers7 records
Segments4 records
Ideal customer profiles3 records
The Alliance for Longevity Initiatives technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
The Alliance for Longevity Initiatives partnerships and signals
Strategic signalPartnerships
Seven partnerships are on record, tiered core, major and minor.
- Longevity Science CaucuscoreA bipartisan Congressional caucus co-founded by A4LI to advance longevity science policy in the U.S. Congress. The caucus was re-launched in April 2025 with members including Reps. Bilirakis, Tonko, Crenshaw, Khanna, Peters, and Liccardo. A4LI helped establish this caucus to serve as a platform for longevity-focused legislative initiatives.
- Georgetown University Medical CentermajorThe 2026 H-SPAN Summit will be held in partnership with Georgetown University Medical Center, combining A4LI's advocacy expertise with Georgetown's academic research capabilities in longevity science.
- Methuselah FoundationcoreDavid Gobel, Co-Founder and CEO of Methuselah Foundation, is featured on A4LI's team page, indicating collaboration in longevity advocacy efforts.
- American Federation for Aging Research (AFAR)coreAFAR's Executive Director Stephanie Lederman is featured on A4LI's team page. AFAR and A4LI share aligned goals in advancing aging research and policy.
- Buck Institute for Research on AgingcoreDr. Eric Verdin, President and CEO of the Buck Institute, and Dr. Brian Kennedy are featured on A4LI's team page, indicating collaborative involvement in longevity science advocacy.
- Lifespan Research InstituteminorKeith Comito, CEO of Lifespan Research Institute, is connected to A4LI through shared advocacy efforts in the longevity space.
- Longevity AngelsminorBrennan O'Connell, Co-Founder of Longevity Angels, is featured on A4LI's team page, connecting early-stage investment community with longevity policy advocacy.
Scale indicators5 records
Recent moves6 records
Expansion highlights6 records
The Alliance for Longevity Initiatives competitors and assessment
Company assessmentDirect peers
- Lifespan Research Institute: Lifespan Research Institute (formerly Lifespan.io) is a longevity advocacy nonprofit supporting scientific research into aging. Its CEO Keith Comito is connected to A4LI through shared advocacy efforts. Both operate as nonprofit advocacy organizations in the longevity science space.
- SENS Research Foundation: SENS Research Foundation is a nonprofit focused on developing regenerative medicine therapies to prevent and reverse age-related disease. Both organizations advocate for increased funding and regulatory support for aging research, making them direct peers in the longevity advocacy ecosystem.
- Hevolution Foundation: Hevolution Foundation is a major nonprofit catalyzing aging research and healthspan extension globally. Its former CSO Dr. Felipe Sierra is involved with A4LI. Both organizations share aligned policy goals around increasing federal funding and public-sector support for aging science.
- Methuselah Foundation: Methuselah Foundation is a longevity-focused nonprofit funding regenerative medicine and aging research. Its Co-Founder/CEO David Gobel is featured on A4LI's team page, signaling direct collaboration. Both organizations advocate for extending healthy human lifespan and supporting longevity science infrastructure.
- Alliance for Aging Research: Alliance for Aging Research is a nonprofit advocating for policies that improve health and independence of older Americans through biomedical research. Both organizations pursue federal funding increases for aging research and engage in policy advocacy on age-related disease.
- American Federation for Aging Research (AFAR): AFAR is a leading nonprofit advancing biomedical aging research through grants and policy advocacy. AFAR's Executive Director is featured on A4LI's team page, indicating close collaboration. Both organizations push for increased federal funding for aging biology and engage with NIH/NIA on research priorities.
- Longevity Science Foundation: Longevity Science Foundation is a nonprofit dedicated to advancing longevity science research and education. Both organizations operate as advocacy-focused nonprofits in the longevity space, working to accelerate research and access to therapies targeting aging.
Emerging players
- Buck Institute for Research on Aging: Buck Institute is the first independent biomedical research institute focused solely on aging. Its President Dr. Eric Verdin and Dr. Brian Kennedy are featured on A4LI's team page. While primarily a research institution, it engages in policy advocacy that aligns with A4LI's mission.
Broad incumbents
- American Cancer Society (ACS): ACS is a major health advocacy organization with substantial federal lobbying infrastructure and funding influence. While focused on cancer rather than aging biology broadly, its model of combining research funding, advocacy, and grassroots organizing represents a framework A4LI could aspire to scale toward.
- National Council on Aging: NCOA is a large, established advocacy organization for older adults focusing on health, economic, and social issues. While more service-oriented than A4LI's longevity science focus, both engage in federal policy advocacy affecting aging populations and funding for aging-related programs.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat4 records
Key risks5 records
Key highlights7 records
Customer concentration
The Alliance for Longevity Initiatives social profiles
Digital presenceThe Alliance for Longevity Initiatives financial estimates
Financial estimateRevenue estimate
Valuation estimate
The Alliance for Longevity Initiatives leadership team
Management profileNumber of profiles
Profiles6 records
The Alliance for Longevity Initiatives funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
The Alliance for Longevity Initiatives M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about The Alliance for Longevity Initiatives
What does The Alliance for Longevity Initiatives do?
A4LI is a 501(c)(4) nonprofit advocacy organization that drives legislation and policy aimed at extending healthy human lifespan. It operates through membership programs, corporate sponsorships, and individual donations to convene lawmakers, biotech innovators, researchers, and supporters around policy goals including increased federal funding for aging research, FDA standards for longevity medicines, and national healthy life expectancy goals. Its core deliverables include the annual H-SPAN Summit D.C., advocacy campaigns, the bipartisan Longevity Science Caucus, and member benefits such as the discount marketplace.
Is The Alliance for Longevity Initiatives a public or private company?
The Alliance for Longevity Initiatives is a private company. It is classified as nonprofit foundation owned and is currently operating.
When was The Alliance for Longevity Initiatives founded?
The Alliance for Longevity Initiatives was founded in 2022. It employs 1 to 10 people.
Where is The Alliance for Longevity Initiatives based?
The Alliance for Longevity Initiatives is headquartered in Virginia, El Salvador, in the Latin America region.
How does The Alliance for Longevity Initiatives make money?
Three revenue lines are on record. Membership fees are the primary driver. The others are sponsorships and donations.
Who are The Alliance for Longevity Initiatives's main competitors?
Direct peers on record are Lifespan Research Institute, SENS Research Foundation, Hevolution Foundation, Methuselah Foundation, Alliance for Aging Research, American Federation for Aging Research (AFAR) and Longevity Science Foundation. Buck Institute for Research on Aging is listed as an emerging player. Broad incumbents are American Cancer Society (ACS) and National Council on Aging.
Does The Alliance for Longevity Initiatives have an API?
No public API is recorded for The Alliance for Longevity Initiatives.
What industry is The Alliance for Longevity Initiatives in?
The Alliance for Longevity Initiatives's product category is Longevity Policy Advocacy. Its primary akta.pro industry code is BPAGAEAF, Elder Services & Aging Support. Its NAICS code is 8134 and its SIC code is 8300.