The Alliance for Longevity Initiatives

What The Alliance for Longevity Initiatives does

The Alliance for Longevity Initiatives (A4LI) is a U.S. 501(c)(4) nonprofit advocacy organization founded in 2022 by Dylan V. Livingston. It is the first organization of its kind in the United States dedicated exclusively to advancing longevity science through public policy. Its mission centers on mitigating age-related diseases (cancer, cardiovascular disease, Alzheimer's) by connecting scientific research with legislative action, with three core advocacy pillars: increasing federal funding for aging biology research (currently less than 1% of the $48.7 billion NIH budget), establishing clear FDA standards to streamline approval of longevity medicines, and advocating for a national healthy life expectancy goal.

A4LI's product surface consists of advocacy initiatives rather than technology products. Core programs include the annual H-SPAN Summit D.C. (its flagship convening event, entering its third year in 2026 in partnership with Georgetown University Medical Center), the bipartisan Longevity Science Caucus in Congress (co-founded by A4LI, re-launched April 2025 with six named Representatives), the H-SPAN Podcast and Scientific Spotlights media properties, a membership program, a Discount Marketplace offering member benefits from longevity product sponsors, and a Letters to Congress advocacy tool. The organization facilitated more than 70 meetings between advocates and Congressional members in 2025.

The business model is a nonprofit advocacy revenue stack with three streams: (1) recurring annual membership fees (pricing undisclosed), (2) corporate sponsorships from longevity biotech companies (disclosed sponsors include Gordian, Agelessrx, Minicircle, Optispan, 100 Plus Capital, Retro Biosciences, and BioAge Labs), and (3) individual donations via the organization's website. The go-to-market motion is community-led, mobilizing members for direct legislative advocacy through petitions, letters, volunteer opportunities, and events. Primary customer segments are longevity biotech investors and innovators, U.S. Congressional members and staff (particularly the bipartisan Longevity Science Caucus), academics and researchers in aging biology, and aligned non-profits. A4LI is founder-controlled, operating with a lean leadership team (founder/president, chair, VP of communications, director of operations, and operations coordinator) plus a scientific advisory board.

Name

The Alliance for Longevity Initiatives

Legal name

The Alliance for Longevity Initiatives

Website

https://a4li.org

Company type

Private

Founded year

2022

Operating status

Operating

Headcount range

1–10 employees

Short description

The Alliance for Longevity Initiatives (A4LI) is the first U.S. 501(c)(4) nonprofit dedicated exclusively to advancing longevity science through public policy advocacy, serving biotech innovators, researchers, and Congressional policymakers since 2022.

Ownership category

akta.pro rank

Product category

Longevity Policy Advocacy

NAICS

Civic and Social Organizations (8134), Voluntary Health Organizations (813212), Religious, Grantmaking, Civic, Professional, and Similar Organizations (813)

SIC

Services-Social Services (8300), Services-Membership Organizations (8600)

akta.pro primary industry

Elder Services & Aging Support (BPAGAEAF)

Keywords

• Longevity policy advocacy
• Geroscience legislation
• Nonprofit advocacy organization
• Healthspan research funding
• Biotech policy lobbying

Headquarters

HQ city

Virginia

HQ country

El Salvador

HQ region

Latin America

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Others

Revenue model

1. Membership fees: A4LI generates revenue through membership fees, offering exclusive access to events, expert discussions, longevity research updates, and discounts on longevity conferences and products. Members help amplify the organization's mission and shape the future of longevity policy.
2. Sponsorships: Corporate sponsors from the longevity biotech sector support A4LI's advocacy efforts. Sponsors include companies like Gordian, Agelessrx, Minicircle, Optispan, 100 Plus Capital, RetroBio, and BioAge.
3. Donations: Individual donations from supporters of longevity science advocacy. The organization accepts donations through various channels including their website donation portal.

Pricing tiers

Go-to-market motion1 record

Distribution channels1 record

Marketing channels7 records

Core offering

A4LI is a 501(c)(4) nonprofit advocacy organization that drives legislation and policy aimed at extending healthy human lifespan. It operates through membership programs, corporate sponsorships, and individual donations to convene lawmakers, biotech innovators, researchers, and supporters around policy goals including increased federal funding for aging research, FDA standards for longevity medicines, and national healthy life expectancy goals. Its core deliverables include the annual H-SPAN Summit D.C., advocacy campaigns, the bipartisan Longevity Science Caucus, and member benefits such as the discount marketplace.

Product overview

The Alliance for Longevity Initiatives (A4LI) is a 501(c)(4) nonprofit policy and advocacy organization rather than a technology product company. Its offerings consist of advocacy programs, membership services, educational content, and events aimed at advancing legislation and policies for extending healthy human lifespan. The core programs include the H-SPAN Podcast and Scientific Spotlights for scientific communication; the annual H-SPAN Summit D.C. as the premier advocacy event; the bipartisan Longevity Science Caucus for congressional engagement; A4LI Membership providing exclusive access and benefits; and a Discount Marketplace offering deals on longevity-related products and services. These offerings work together to advance A4LI's mission of accelerating equitable access to next-generation longevity therapies through political and social action.

Differentiator

Problem solved

Functional benefit

Products and services

• A4LI Membership Program Annual membership program for individuals aligned with longevity science policy, offering exclusive access to events, expert discussions, updates on cutting-edge longevity research, and discounts on longevity conferences and products.
• H-SPAN Summit D.C. Annual flagship event in Washington, D.C. bringing together leaders, advocates, and innovators to advance legislative initiatives promoting healthier human lifespan.
• Corporate Sponsorship Program Sponsorship program for longevity biotech companies to support A4LI's advocacy efforts in exchange for visibility and alignment with longevity science policy initiatives.

Quantifiable outcome

• Facilitated over 70 meetings between advocates and Congressional members in 2025
• +3 more outcomes

Named customers7 records

Segments4 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Partnerships

Seven partnerships are on record, tiered core, major and minor.

• Longevity Science CaucuscoreStrategic or Co-development Partner · 21 February 2023A bipartisan Congressional caucus co-founded by A4LI to advance longevity science policy in the U.S. Congress. The caucus was re-launched in April 2025 with members including Reps. Bilirakis, Tonko, Crenshaw, Khanna, Peters, and Liccardo. A4LI helped establish this caucus to serve as a platform for longevity-focused legislative initiatives.
• Georgetown University Medical CentermajorStrategic or Co-development PartnerThe 2026 H-SPAN Summit will be held in partnership with Georgetown University Medical Center, combining A4LI's advocacy expertise with Georgetown's academic research capabilities in longevity science.
• Methuselah FoundationcoreStrategic or Co-development PartnerDavid Gobel, Co-Founder and CEO of Methuselah Foundation, is featured on A4LI's team page, indicating collaboration in longevity advocacy efforts.
• American Federation for Aging Research (AFAR)coreStrategic or Co-development PartnerAFAR's Executive Director Stephanie Lederman is featured on A4LI's team page. AFAR and A4LI share aligned goals in advancing aging research and policy.
• Buck Institute for Research on AgingcoreStrategic or Co-development PartnerDr. Eric Verdin, President and CEO of the Buck Institute, and Dr. Brian Kennedy are featured on A4LI's team page, indicating collaborative involvement in longevity science advocacy.
• Lifespan Research InstituteminorStrategic or Co-development PartnerKeith Comito, CEO of Lifespan Research Institute, is connected to A4LI through shared advocacy efforts in the longevity space.
• Longevity AngelsminorStrategic or Co-development PartnerBrennan O'Connell, Co-Founder of Longevity Angels, is featured on A4LI's team page, connecting early-stage investment community with longevity policy advocacy.

Scale indicators5 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Lifespan Research Institute: Lifespan Research Institute (formerly Lifespan.io) is a longevity advocacy nonprofit supporting scientific research into aging. Its CEO Keith Comito is connected to A4LI through shared advocacy efforts. Both operate as nonprofit advocacy organizations in the longevity science space.
• SENS Research Foundation: SENS Research Foundation is a nonprofit focused on developing regenerative medicine therapies to prevent and reverse age-related disease. Both organizations advocate for increased funding and regulatory support for aging research, making them direct peers in the longevity advocacy ecosystem.
• Hevolution Foundation: Hevolution Foundation is a major nonprofit catalyzing aging research and healthspan extension globally. Its former CSO Dr. Felipe Sierra is involved with A4LI. Both organizations share aligned policy goals around increasing federal funding and public-sector support for aging science.
• Methuselah Foundation: Methuselah Foundation is a longevity-focused nonprofit funding regenerative medicine and aging research. Its Co-Founder/CEO David Gobel is featured on A4LI's team page, signaling direct collaboration. Both organizations advocate for extending healthy human lifespan and supporting longevity science infrastructure.
• Alliance for Aging Research: Alliance for Aging Research is a nonprofit advocating for policies that improve health and independence of older Americans through biomedical research. Both organizations pursue federal funding increases for aging research and engage in policy advocacy on age-related disease.
• American Federation for Aging Research (AFAR): AFAR is a leading nonprofit advancing biomedical aging research through grants and policy advocacy. AFAR's Executive Director is featured on A4LI's team page, indicating close collaboration. Both organizations push for increased federal funding for aging biology and engage with NIH/NIA on research priorities.
• Longevity Science Foundation: Longevity Science Foundation is a nonprofit dedicated to advancing longevity science research and education. Both organizations operate as advocacy-focused nonprofits in the longevity space, working to accelerate research and access to therapies targeting aging.

Emerging players

• Buck Institute for Research on Aging: Buck Institute is the first independent biomedical research institute focused solely on aging. Its President Dr. Eric Verdin and Dr. Brian Kennedy are featured on A4LI's team page. While primarily a research institution, it engages in policy advocacy that aligns with A4LI's mission.

Broad incumbents

• American Cancer Society (ACS): ACS is a major health advocacy organization with substantial federal lobbying infrastructure and funding influence. While focused on cancer rather than aging biology broadly, its model of combining research funding, advocacy, and grassroots organizing represents a framework A4LI could aspire to scale toward.
• National Council on Aging: NCOA is a large, established advocacy organization for older adults focusing on health, economic, and social issues. While more service-oriented than A4LI's longevity science focus, both engage in federal policy advocacy affecting aging populations and funding for aging-related programs.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks5 records

Key highlights7 records

Customer concentration

• Xx.com/theA4LI
• YouTubeyoutube.com/@theallianceforlongevityini9383
• Facebookfacebook.com/a4li.org
• LinkedInlinkedin.com/company/the-alliance-for-longevity-initiatives

Revenue estimate

Valuation estimate

Number of profiles

Profiles6 records

Funding overview

Funding rounds

Investors

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M&A

Investments

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Frequently asked questions about The Alliance for Longevity Initiatives