NeuroVascular Quality Initiative-Quality Outcomes Database

What NeuroVascular Quality Initiative-Quality Outcomes Database does

NVQI-QOD is a physician-led clinical registry founded in 2013 and governed by the Society of NeuroInterventional Surgery Patient Safety Organization (SNIS PSO), with co-stewardship from the NeuroPoint Alliance. The registry captures 100% of neurovascular procedures — including demographic, procedural, and post-operative data with long-term (one year or longer) outcomes — across four clinical modules: Acute Ischemic Stroke, Cerebral Aneurysm, Cerebral Venous (newly launched 2026), and Neuro Embolization (expanded from the legacy AVM module in 2026). It is built on the Fivos PATHWAYS cloud platform, which provides real-time data capture, PSO Reports with drill-down dashboards at the PRIMPROCID level, Kaplan-Meier outcome calculations, downloadable reports, and an optional EMR/clinical system integration service. The platform also hosts partner registries with the Society for Vascular Surgery (VQI Carotid Endarterectomy, Carotid Artery Stent, and the TCAR Surveillance Project).

The organization serves three customer segments: medical centers and hospitals (primary, enterprise subscribers), physicians/surgeons in neurointerventional disciplines (primary users), and device manufacturers (secondary, real-world evidence buyers). Revenue is generated through per-institution subscription fees scaled by the number of modules selected (two contracts required: SNIS PSO and Fivos) and through industry data services that provide real-world evidence for FDA/EU MDR regulatory submissions, R&D, and commercial use. Pricing is not publicly disclosed, and EMR integration is offered as a paid add-on.

NVQI-QOD operates as a quality-improvement initiative rather than a commercial enterprise: it is structured as a nonprofit under its parent PSO, has no venture or private equity backing, and uses sales-led enterprise field sales with a formal contact/join contracting process, annual member meetings, and monthly Data Coordinator meetings as its primary go-to-market motions. As of 2025 the registry spanned 41 sites across 25 states with 231 physicians, ~30,000 procedures and >27,000 patients recorded; in 2026 it expanded into Canada and onboarded its first non-U.S. centers.

Name

NeuroVascular Quality Initiative-Quality Outcomes Database

Legal name

NeuroVascular Quality Initiative-Quality Outcomes Database (NVQI-QOD)

Website

https://nvqi-qod.org

Company type

Private

Founded year

2013

Operating status

Operating

Headcount range

11–50 employees

Short description

NVQI-QOD is a physician-led, nonprofit clinical registry capturing neurovascular procedure and long-term outcome data from U.S. and Canadian hospitals, physicians, and device manufacturers, governed by the SNIS Patient Safety Organization and built on the Fivos PATHWAYS platform.

Ownership category

akta.pro rank

Headquarters

HQ city

Fairfax

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Technology or R&D, Personnel, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Registry Participation Fees: Hospitals and institutions pay fees calculated per institution based on the number of modules selected. Two separate contracts are required: one with the SNIS PSO and one with Fivos for database management services.
2. Industry Data Services: Device manufacturers can access real-world data for health economics, research and development, internal sales and marketing, and regulatory needs. Custom data elements and follow-up requirements can be added for specific industry projects.

Pricing tiers

Go-to-market motion2 records

Distribution channels2 records

Marketing channels5 records

Core offering

NVQI-QOD is a physician-led clinical registry that captures 100% of neurovascular procedures—including demographic, procedure, and long-term (one year or longer) outcome data—for stroke, cerebral aneurysm, cerebral venous, and neuro embolization cases. Built on the Fivos PATHWAYS cloud platform, it delivers benchmarking dashboards, PSO reports, and a peer network for hospitals, physicians, and device manufacturers across North America.

Product overview

NVQI-QOD operates as a platform-plus-modules architecture. The core product is the NVQI-QOD Registry, a physician-led clinical registry governed by the SNIS Patient Safety Organization, built on the Fivos PATHWAYS cloud-based technology platform. Four primary clinical modules extend from this core: the Acute Ischemic Stroke Module, Cerebral Aneurysm Module, Cerebral Venous Registry (CVR) Module, and the Neuro Embolization (NE) Module (formerly AVM). These modules feed into PSO Reports/Dashboards for benchmarking and performance tracking. Additionally, partner registries including VQI Carotid Endarterectomy, VQI Carotid Artery Stent, and TCAR Surveillance Project are offered through agreements with the Society for Vascular Surgery. A Research Data Request Service allows qualified researchers to access non-identifiable datasets for approved studies.

Differentiator

Problem solved

Functional benefit

Products and services

• NVQI-QOD Registry A physician-led clinical registry governed by the SNIS Patient Safety Organization that captures 100% of neurovascular procedures including demographic, procedural, and long-term (one-year or longer) patient outcomes data for quality improvement, benchmarking, and research. Targeted at medical centers, hospitals, and physicians performing neurovascular procedures.
• Acute Ischemic Stroke Module A registry module capturing Acute Ischemic Stroke (AIS) procedures performed within 24 hours of stroke symptom onset, including endovascular thrombolysis or mechanical embolectomy for acute cervical or intracranial occlusion. Targets 80% follow-up rate at 90 days and is offered to participating neurovascular centers.
• Cerebral Aneurysm Module A registry module covering all cerebral aneurysms treated percutaneously or through craniotomy, tracking both acute and elective presentations with a required minimum 80% follow-up rate within one year. Designed for neurovascular centers treating aneurysm patients.
• Cerebral Venous Registry (CVR) Module The first dedicated registry module for cerebral venous disorders and stenting procedures, covering endovascular venous stenting, embolization of cerebral venous diverticula, and embolization of abnormally dilated emissary veins. Addresses diagnoses including idiopathic intracranial hypertension (IIH), pulsatile tinnitus, and brain fog for neurovascular centers.
• Neuro Embolization (NE) Module Formerly the AVM module, this expanded registry tracks destructive embolization procedures for brain AVMs, dural arteriovenous fistulas (dAVFs), chronic subdural hematoma, MMA embolizations, epistaxis, and other brain/head/neck embolizations. Includes surgical and radiation treatment documentation with a minimum 80% follow-up rate.
• PSO Reports / Dashboards Benchmarking dashboards providing key metrics for registry participants, including the Acute Ischemic Stroke PSO Report and Cerebral Aneurysm PSO Report with drill-down capabilities, Kaplan-Meier calculations for one-year outcomes, and downloadable reports in multiple formats. Offered to participating neurovascular centers.
• VQI Carotid Endarterectomy Registry Partner registry offered under agreement with the Society for Vascular Surgery, enabling NVQI-QOD members to collect procedure data on carotid endarterectomy procedures. Requires a separate contract with SVS PSO.
• VQI Carotid Artery Stent Registry Partner registry offered under agreement with the Society for Vascular Surgery, enabling NVQI-QOD members to collect carotid artery stent procedure data, with the opportunity to participate in the CREST2 Registry and CREST2 Trial. Requires a separate contract with SVS PSO.
• TCAR Surveillance Project A surveillance registry managed by the SVS PSO monitoring transcarotid stents placed with reversed blood flow. Compares TCAR outcomes with standard carotid endarterectomy (CEA) and benchmarks outcomes against other VQI participants.
• Research Data Request Service Provides non-identifiable datasets to qualified researchers from Active NVQI-QOD participants for analysis. Researchers submit requests via the SNIS PSO Executive Director for registries including Acute Ischemic Stroke, Cerebral Aneurysm, Cerebral Venous, and Neuro Embolization.

Quantifiable outcome

• Captures 100% of procedures with comprehensive demographic, procedure and post-op data
• +1 more outcomes

Named customers9 records

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration1 record

Feature4 records

Partnerships

Five partnerships are on record, tiered core and minor.

• Society of NeuroInterventional Surgery (SNIS) PSOcoreStrategic or Co-development Partner · 8 July 2019The SNIS PSO provides comparative data analysis and oversight of quality improvement activities for NVQI-QOD. The registry is governed by the SNIS PSO, which takes direction from a Governing Council comprised of representatives of SNIS and NPA. SNIS PSO provides PSO Reports to registry participants.
• NeuroPoint Alliance (NPA)coreStrategic or Co-development Partner · 8 July 2019NPA partnered with SNIS NVQI in July 2019 to form the unified NVQI-QOD registry. The Governing Council is comprised of representatives from both NPA and SNIS. NPA was established in 2008 by the American Association of Neurological Surgeons (AANS).
• FivoscoreTechnology or IntegrationFivos is the exclusive technology provider of the NVQI-QOD. The Fivos PATHWAYS clinical data performance platform provides real-time data capture and reporting capabilities. Fivos facilitates contracting for both agreements and provides EMR/clinical system integration for an additional fee.
• Society for Vascular Surgery (SVS)minorStrategic or Co-development PartnerUnder agreement with SVS, NVQI-QOD offers members the opportunity to collect procedure data on the VQI Carotid Endarterectomy Registry and Carotid Artery Stent Registry. Participation requires a separate contract with SVS PSO.
• Society for Vascular Surgery Patient Safety Organization (SVS PSO)minorStrategic or Co-development PartnerSVS PSO oversees the TCAR Surveillance Project (TSP), a surveillance registry monitoring the safety and effectiveness of transcarotid stents. TSP participants must enter cases in the SVS VQI CAS Registry.

Scale indicators8 records

Recent moves9 records

Expansion highlights5 records

Direct peers

• Vascular Quality Initiative (VQI): SVS-sponsored multi-module vascular surgery registry (carotid, aortic, peripheral). Already a partner registry to NVQI-QOD via SVS agreement — directly comparable platform-plus-modules architecture for procedural outcomes in adjacent vascular procedure categories.
• NeuroPoint Alliance (NPA): AANS-established neurosurgery quality organization that co-governs NVQI-QOD via the joint Governing Council. Operates adjacent neurosurgical registries (including the original QOD-NV that merged into NVQI-QOD in 2019), making it a near-twin governance peer.
• Get With The Guidelines - Stroke: AHA's flagship stroke quality improvement registry capturing hospital-level stroke care metrics and outcomes. Most directly comparable to NVQI-QOD's Acute Ischemic Stroke module as a competing neurovascular clinical registry serving similar US hospital customers with similar quality benchmarking goals.

Others

• Fivos Health: NVQI-QOD's exclusive technology platform provider (PATHWAYS), also serving other medical-society registries. Comparable as a clinical registry technology enabler and a key infrastructure peer for any registry built on its stack.

Broad incumbents

• IQVIA: Global real-world evidence and clinical data provider serving many of the same device-manufacturer customers NVQI-QOD targets with industry data services. Comparable in the device-manufacturer RWE sales motion though vastly larger in scale and scope.
• ACS NSQIP: American College of Surgeons National Surgical Quality Improvement Program — a premier surgical outcomes registry with hospital pay-for-participation model and benchmarking reports. Directly comparable commercial/governance model and surgical outcomes use case.
• Society of Thoracic Surgeons (STS) National Database: Long-established, society-governed, multi-module surgical outcomes registry widely considered the gold standard for clinical quality databases. Comparable in architecture, governance model, and physician-led design philosophy, though focused on cardiothoracic surgery.
• ACC National Cardiovascular Data Registry (NCDR): American College of Cardiology's suite of hospital-based outcomes registries. Highly comparable in mission, society-endorsed governance, multi-module structure, and hospital benchmarking value proposition, though focused on cardiovascular procedures.

Emerging players

• ArborMetrix: Clinical registry and analytics platform used by specialty societies (e.g., pediatric, OB/GYN, ophthalmology) to power outcomes reporting. Directly comparable technology peer to Fivos and a potential alternative platform for society-sponsored registries.
• FIGmd: Clinical data registry and EHR-integration platform serving specialty medical societies and quality programs. Comparable as a clinical registry technology vendor and a peer to Fivos in powering society-endorsed registries.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks5 records

Key highlights7 records

Customer concentration

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about NeuroVascular Quality Initiative-Quality Outcomes Database