Expanse Medical

What Expanse Medical does

Expanse Medical is a privately held, engineering-first medical technology venture studio headquartered in Pleasanton, California, with a second facility in Providence, Rhode Island, established in late 2025 with support from the Rhode Island Life Science Hub. The company is led by founder and CEO Eitan Konstantino (PhD, Technion), with Shlomi Nachman (former Company Group Chairman of Cardiovascular & Specialty Solutions at Johnson & Johnson) serving as Chairman and Sean Zhang (VP BD at Genesis Medtech) as Board Director. Expanse develops medical devices across vascular, neurovascular, lymphatic, and urological care using a first-principles engineering approach, with the leadership team collectively holding approximately 200 patents and applications worldwide.

The portfolio includes five active programs: FlowPhysix, commercializing the FLOWRUNNER Aspiration System following its April 2024 FDA 510(k) clearance for peripheral thrombectomy; Valorian Medical Technologies, a next-generation erectile dysfunction device for PDE5 non-responders; REV Neuro, a neurovascular delivery system built under a Build-to-Buy contract and sold to a Fortune 500 within 12 months of FDA approval; Dragon, a next-generation neurovascular therapeutic system in active development; and a Lymphatic Disorders Program developing the first implantable-device-based solution targeting 250M+ patients globally. Earlier-generation technologies developed by leadership (AngioSculpt, Chocolate PTA balloons, Chocolate Touch DCB) have been licensed to or distributed by Medtronic, Teleflex, Philips, Johnson & Johnson, Boston Scientific, and Genesis Medtech.

Expanse operates a dual business model combining Build-to-Buy turnkey device development programs for Fortune 500 strategics and selective incubation and spinout of independent portfolio companies. Revenue streams include professional services for Build-to-Buy engagements, hardware sales through spun-out companies such as FlowPhysix, and IP licensing and royalty arrangements on prior-generation patents and technologies. Distribution is mixed: direct enterprise commercialization via FlowPhysix in the US, channel partnerships (3comma Medical) for select international markets, and strategic OEM/licensing arrangements with global medtech majors. The company emphasizes in-house design controls, verification and validation, regulatory execution, and manufacturing transfer delivered as a complete documentation package ready for strategic acquisition.

Name

Expanse Medical

Legal name

Expanse Medical Inc.

Website

https://expansemedical.com

Company type

Private

Founded year

2020

Operating status

Operating

Headcount range

11–50 employees

Short description

Expanse Medical is an engineering-first medical technology venture studio that develops and commercializes medical devices across vascular, neurovascular, lymphatic, and urological care, operating a dual model of Build-to-Buy programs for Fortune 500 medtech strategics and incubated portfolio company spinouts.

Ownership category

akta.pro rank

Headquarters

HQ city

Pleasanton

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Technology or R&D, Operations, Marketing or Sales, Supply Chain

Revenue model

1. Build-to-Buy Device Development Services: Turnkey medical device development services for Fortune 500 and multi-billion dollar international medtech companies. Expanse co-defines requirements, creates and delivers a device and documentation package built for acquisition, managing the process from design through FDA clearance/approval and transferring the program ready for scaling and commercialization.
2. Venture Spinouts: Expanse incubates medical device opportunities and spins out independent companies at optimal milestones. FlowPhysix was incubated in 2022, spun off in April 2024, and is now commercializing the FLOWRUNNER Aspiration System. Valorian Medical Technologies is another spinout advancing erectile dysfunction device platform.
3. IP Licensing and Technology Transfer: Patent portfolios licensed to leading multinational companies. Technologies including AngioSculpt and Chocolate have been acquired or distributed by Medtronic, Teleflex, Philips, J&J, and Boston Scientific. Team has generated approximately 200 patents and patent applications worldwide.

Go-to-market motion3 records

Distribution channels3 records

Marketing channels3 records

Core offering

Expanse Medical is an engineering-first medtech venture studio that incubates, develops, and transfers medical devices through a dual model: Build-to-Buy turnkey device development services for Fortune 500 medtech companies, and the creation and spinout of portfolio companies commercializing proprietary devices. Platforms span vascular, neurovascular, lymphatic, and urological care, with active products including the FLOWRUNNER Aspiration System, neurovascular delivery systems, and implantable lymphatic disorder devices.

Product overview

Expanse Medical is an engineering-first medtech venture studio that operates a dual model of building internal portfolio companies and offering Build-to-Buy services to strategic partners. Its portfolio includes: FlowPhysix (spun out in April 2024), which commercializes the FLOWRUNNER Aspiration System for peripheral thrombectomy; Valorian Medical Technologies for erectile dysfunction; Dragon and REV Neuro for neurovascular applications; and a lymphatic disorders program. Additional offerings include PTA balloon product families, Neuro Micro catheters, and embolization coils. The Build-to-Buy Solutions service provides turnkey device development from design through FDA clearance and transfer.

Differentiator

Problem solved

Functional benefit

Quantifiable outcome

• $1B+ in global sales generated from products invented by the team
• +5 more outcomes

Segments6 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature7 records

Partnerships

Eight partnerships are on record, tiered core and flagship.

• Rhode Island Life Science Hub (RILSH)coreStrategic or Co-development Partner · 11 November 2025Expanse Medical received support from the Rhode Island Life Science Hub for expansion to Providence, Rhode Island. This partnership enables Expanse to accelerate East Coast partnerships and launch its newest portfolio company, Valorian Medical Technologies. The facility connects engineering talent, clinicians, and investors.
• 3comma Medical / 3comma Medical GmbHcoreChannel Partner/ Reseller/ Distributor · 11 September 2024FlowPhysix announced strategic partnership with 3comma Medical for international distribution of the FLOWRUNNER Aspiration System. 3comma Medical serves as the international commercial partner, distributing the innovative thrombectomy device in select global markets outside the US.
• PhilipsflagshipOEM/ Whitelabel/ Licensing PartnerPhilips acquired/distributed AngioSculpt PTA/PTCA balloon technology, one of Expanse leadership's invented products. This represents a significant licensing and distribution relationship.
• MedtronicflagshipOEM/ Whitelabel/ Licensing PartnerMedtronic acquired/distributed Chocolate PTA balloon technology, invented by Expanse leadership. This represents a major product licensing relationship.
• TeleflexflagshipOEM/ Whitelabel/ Licensing PartnerTeleflex acquired/distributed Glider PTCA balloon (based on Chocolate technology), invented by Expanse leadership. Significant commercial distribution relationship.
• Genesis MedtechflagshipOEM/ Whitelabel/ Licensing PartnerGenesis Medtech acquired/distributed Chocolate Touch DCB (drug-coated balloon) and Eitan Konstantino served as CTO. Major ongoing partnership with Expanse leadership.
• Johnson & JohnsonflagshipOEM/ Whitelabel/ Licensing PartnerJ&J acquired/distributed Expanse leadership-invented products. Shlomi Nachman, Chairman of Expanse, previously served as Company Group Chairman of Cardiovascular & Specialty Solutions and Vision Groups at J&J before retiring in January 2023.
• Boston ScientificflagshipOEM/ Whitelabel/ Licensing PartnerBoston Scientific acquired/distributed Expanse leadership-invented products. Represents a key distribution partner for Expanse-developed technologies.

Scale indicators5 records

Recent moves10 records

Expansion highlights5 records

Broad incumbents

• Medtronic: Medtronic is a broad medtech incumbent that licenses Expanse leadership's Chocolate PTA balloon technology and competes across vascular, neurovascular, and peripheral intervention. Relevant as both a key Build-to-Buy customer and as a benchmark for the strategic partners Expanse is targeting.
• Stryker: Stryker is a broad medtech incumbent with a neurovascular portfolio (acquired through the purchase of Cerenovus-related assets) that competes with Expanse's Dragon/REV Neuro, and is the type of Fortune 500 strategic partner that engages Expanse via the Build-to-Buy model. Relevant both as a competitor and as a potential Build-to-Buy acquirer.
• Teleflex: Teleflex is a broad medtech incumbent that distributes the Glider PTCA (based on Expanse leadership's Chocolate technology) and competes across interventional cardiology and vascular access. Relevant as a strategic Build-to-Buy partner and as a comparator in the peripheral/structural heart device space.
• Johnson & Johnson (MedTech): J&J is a broad medtech incumbent that has acquired/distributed Expanse leadership-invented products and where Chairman Shlomi Nachman previously led the Cardiovascular & Specialty Solutions Group. Comparable as a large incumbent that both competes in and is a strategic customer of Expanse-developed technologies.

Direct peers

• Rapid Medical: Rapid Medical is a neurovascular device company developing adjustable stent retrievers and access catheters — directly comparable to Expanse's neurovascular portfolio (Dragon, REV Neuro). Similar business model of engineering-driven differentiated devices for interventional neuroradiology.
• Penumbra: Penumbra is a direct competitor to FlowPhysix in peripheral thrombectomy with its Indigo aspiration system, and competes in neurovascular where Expanse's Dragon and REV Neuro programs operate. Highly relevant as a peer in the vascular thrombectomy and neurovascular device spaces that Expanse targets.
• Imperative Care: Imperative Care is a neurovascular device company competing in the same therapeutic category as Expanse's Dragon and REV Neuro programs, with a stroke-focused platform and aspiration catheters. Relevant peer because both target neurovascular intervention with engineered catheter-based solutions.
• Inari Medical: Inari Medical is a direct competitor to FlowPhysix/FLOWRUNNER in the peripheral venous and arterial thrombectomy market with its FlowTriever and InThrill systems. Comparable as a venture-backed, focused peripheral thrombectomy player that scaled via clinical evidence and direct sales.
• AngioDynamics: AngioDynamics is a peripheral vascular device company with thrombectomy (AlphaVac) and vascular access portfolios, directly competing with FlowPhysix's FLOWRUNNER. Relevant as a peer operating in the same peripheral vascular/thrombectomy category.

Emerging players

• ExploraMed: ExploraMed is a medical device incubator founded by NEA and serial medtech entrepreneur Josh Makower, with a similar business model of incubating and spinning out device companies (e.g., Moximed, NeoTract). Directly comparable as a medtech venture studio operating with a parallel spinout philosophy.

Market position

Strengths4 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/expanse-medical

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Subsidiaries5 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Expanse Medical