Project Main Street Inc.

Name

Project Main Street Inc.

Legal name

Project Main Street, Inc.

Website

https://projectmainst.org

Company type

Private

Founded year

2006

Operating status

Operating

Headcount range

1–10 employees

Ownership category

akta.pro rank

Product category

ALS Patient Financial Assistance Grants

NAICS

Voluntary Health Organizations (813212), Other Grantmaking and Giving Services (813219)

SIC

Services-Social Services (8300)

akta.pro primary industry

Disease-Specific Research & Support (e.g., Cancer, Diabetes, ALS) (BPAGACAA)

akta.pro secondary industries

Public Charities & Grantmaking Intermediaries (BPAGAKAE), Community Fundraisers & Charity Events (Gala/Walks excluded) (MPAGAEAK)

Keywords

• ALS financial assistance
• Nonprofit grant programs
• ALS patient care funding
• Community fundraising events
• Charitable healthcare grants

Headquarters

HQ city

West New York

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Marketing or Sales, Operations, Others

Revenue model

1. Individual Donations: Tax-deductible donations from individuals made online via PayPal or by mail. Accepts MasterCard, Visa, and American Express.
2. Corporate Matching Gifts: Many companies match their employees' gifts to charity, amplifying the impact of individual donations.
3. Stock Donations: Donors can contribute appreciated shares of stock, bonds, and mutual funds to support the organization.
4. Honor/Memorial Giving: Donations made to commemorate birthdays, anniversaries, weddings, births, or in memory of loved ones, with acknowledgment cards sent on behalf of the donor.

Go-to-market motion1 record

Distribution channels3 records

Marketing channels8 records

Core offering

Project Main Street is a 501(c)(3) nonprofit that provides unrestricted financial grants to individuals living with ALS to help cover care and related expenses. Grants are funded through individual donations, corporate matching gifts, stock contributions, and honor/memorial giving, and are distributed via a referral-based application process to patients experiencing financial hardship. Supporting fundraising activities include the annual Tim Sheehy Gala & Softball Classic, community benefit concerts, wine tasting events, and an END ALS merchandise storefront.

Product overview

Project Main Street is a New York-based 501(c)(3) non-profit organization founded in 2006 that provides unrestricted financial grants to individuals living with ALS. The core offering is the Financial Grants Program, which distributes hundreds of grants annually to cover home healthcare, medical expenses, insurance costs, and home modifications. This is supplemented by the annual Tim Sheehy Gala & Softball Classic fundraising event, an END ALS merchandise store for additional fundraising, and an online donation platform powered by PayPal. The organization has raised more than $3 million since inception and operates on the belief that neighbors helping neighbors can create lasting change in the ALS community.

Differentiator

Problem solved

Functional benefit

Quantifiable outcome

• $3 million+ raised and distributed since 2006, with hundreds of grants given per year

Named customers1 record

Segments2 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration1 record

Partnerships

One partnership is on record.

• Team GleasoncoreStrategic or Co-development Partner · 16 April 2018Project Main Street and Team Gleason collaborate to distribute grants providing direct financial assistance to people living with ALS. The partnership has distributed grants covering the cost of home health care, medical and insurance expenses, and home upgrades for wheelchair accessibility. The Tim Sheehy Gala and Softball Classic events are co-hosted with Team Gleason.

Scale indicators3 records

Recent moves5 records

Expansion highlights4 records

Emerging players

• I AM ALS: A patient-driven community and advocacy organization founded in 2019 that combines advocacy, patient support, and direct services. It represents a newer model of community-led ALS nonprofits with similar grassroots DNA to Project Main Street.
• Project ALS: Founded by Jenifer Estess and family, Project ALS funds research and some patient care initiatives. While more research-focused than Project Main Street, it operates in the same disease niche and shares the patient-empathy-driven origin story.
• ALS Therapy Development Institute (ALS TDI): The world's largest nonprofit biotech focused exclusively on ALS research. While primarily research-focused, it operates in the same rare-disease nonprofit space, competes for ALS-cause donors, and shares small-team operational dynamics.
• Answer ALS: A collaborative ALS research initiative providing data and resources to the ALS community. While more research-focused, it operates in the same disease cause area and competes for high-net-worth ALS donors and foundation grant funding.

Broad incumbents

• Muscular Dystrophy Association (MDA): A large established nonprofit serving people with neuromuscular diseases including ALS, providing research funding, clinical care, and some direct patient support. Although broader in disease scope, it competes for ALS-specific donors and offers similar care-related services.
• ALS Association (ALSA): The largest ALS-focused nonprofit in the United States, funding research, care services, advocacy, and some direct patient support. While far larger and broader in scope, it competes for the same donor dollars and addresses overlapping patient needs, making it a relevant incumbent comparable.

Direct peers

• Team Gleason: Founded by former NFL player Steve Gleason after his ALS diagnosis, Team Gleason provides similar direct financial assistance, technology, and life adventures to people living with ALS. Project Main Street explicitly co-hosts events and distributes grants with Team Gleason, making them the closest peer in mission and model.
• Compassionate Care ALS (CCALS): CCALS provides direct support services, education, and grants to ALS patients and families, with a strong focus on individualized care. Like Project Main Street, it emphasizes direct financial assistance and community-based support rather than primarily research funding.
• Les Turner ALS Foundation: One of the longest-standing ALS nonprofits, providing patient services, support groups, and direct financial assistance to people living with ALS in the Chicago area and beyond. Its multi-pronged care model parallels Project Main Street's patient-direct grant approach.
• LiveLikeLou Foundation: Established in memory of baseball legend Lou Gehrig, LiveLikeLou provides direct financial assistance, equipment, and home modifications to ALS patients and families. Its disease-specific, patient-focused grantmaking is closely comparable to Project Main Street's mission.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat3 records

Key risks6 records

Key highlights6 records

Customer concentration

• Instagraminstagram.com/projectmainst
• LinkedInlinkedin.com/company/project-main-street-inc.

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Project Main Street Inc.