Profound Autism Alliance
- Company typePrivate
- Founded2023
- HeadquartersWellesley Hills, United States
- Headcount1–10
- GTM typeB2C
- OfferingServices
What Profound Autism Alliance does
Profound Autism Alliance is a 501(c)(3) nonprofit advocacy organization founded in 2023 as a private foundation and re-established as a public charity (Profound Autism Alliance Public Charity, Inc.) in January 2025, operating from Wellesley Hills, Massachusetts. The organization focuses on the subset of the autism spectrum it terms "profound autism" — individuals (often nonverbal) requiring 24-hour lifetime support — and runs programs spanning state and federal advocacy (including a Profound Autism Day proclamation campaign that secured 15 states in its first year), caregiver and sibling support programs (Sibling Action Network, Caregivers Connected, Dignity Project, Special Interest Groups), physician training (ECHO Autism: Intense Behavior), research facilitation through the ARIA IMPACT Network, a Resource Network database, and an annual Profound Autism Summit.
Its product surface is essentially non-technological: it is a community-organizing and research-coordination entity built on standard SaaS tooling (Qgiv for donations, VoterVoice for advocacy, BehaviorLive for virtual events, iGive and Kroger Community Rewards for affiliate giving, CarEasy for vehicle donations). The organization does not develop proprietary technology, AI/ML systems, or data assets; instead, it leverages its position to convene top-tier research institutions including SickKids, Holland Bloorview, Columbia University Irving Medical Center, Weill Cornell Medicine, UCLA, and Children's Hospital Los Angeles, which have received up to $17.25 million in grants per site through the ARIA IMPACT Network that the alliance helps facilitate.
Revenue is generated entirely through donations, community fundraising, corporate giving affiliate programs, and grant funding; no products or services are sold. Its customer base spans caregivers and family members, people with profound autism, autism researchers, and healthcare professionals, with go-to-market executed via community-led advocacy, event-driven engagement (the annual Summit plus monthly ECHO and state advocacy meetings), and direct-to-consumer outreach through its website and newsletter. Notable credentials include 501(c)(3) tax-exempt status and Guidestar Platinum Transparency 2024 certification.
Profound Autism Alliance firmographics
Firmographics- Name
- Profound Autism Alliance
- Legal name
- Profound Autism Alliance Public Charity, Inc.
- Website
- https://profoundautism.org
- Company type
- Private
- Founded year
- 2023
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Ownership category
- akta.pro rank
Profound Autism Alliance industry classification
Industry- Product category
- Disability Advocacy Services
- NAICS
- Social Advocacy Organizations (8133), Other Individual and Family Services (624190), Civic and Social Organizations (813410)
- SIC
- Services-Social Services (8300), Services-Membership Organizations (8600), Services-Misc Health & Allied Services, Nec (8090)
- akta.pro primary industry
- Autism Parent/Caregiver Education & Training (School-Linked) (EDAKAKAJ)
- akta.pro secondary industry
- Autism Teacher Training & Professional Development (EDAKAKAL)
Keywords
Where Profound Autism Alliance is headquartered
LocationHeadquarters
- HQ city
- Wellesley Hills
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Profound Autism Alliance business model
Business model- GTM type
- B2C
- Offering type
- Services
- Cost components
- Personnel, Operations, Marketing or Sales, Technology or R&D, Others
Revenue model
- Individual Donations: Tax-deductible donations from individuals through online portal (Qgiv), mail-in checks, and monthly recurring donation options. The organization is a 501(c)(3) nonprofit with EIN 92-0405006.
- Fundraising Events: Community members can create personal fundraisers around events like backyard barbecues, birthday celebrations, or corporate gatherings. The organization facilitates these through their platform.
- Corporate Giving Programs: Partnerships with retailers including iGive (percentage of purchases donated), Kroger Community Rewards (for purchases in 35 states), and car donation programs.
- Program Funding: The organization funds programs like ECHO Autism: Intense Behavior and receives grant funding to support research participation and advocacy initiatives.
Go-to-market motion3 records
Distribution channels6 records
Marketing channels8 records
Profound Autism Alliance product offering
Product offeringCore offering
Profound Autism Alliance is a 501(c)(3) nonprofit that advocates on behalf of individuals with profound autism through state and federal policy campaigns, facilitates participation in clinical research via the ARIA IMPACT Network, and operates caregiver and sibling community programs (Sibling Action Network, Caregivers Connected, Dignity Project, Special Interest Groups). It also runs the annual Profound Autism Summit, Profound Autism Day recognition campaign, and the ECHO Autism: Intense Behavior physician training program.
Product overview
Profound Autism Alliance is a nonprofit advocacy organization (501(c)(3)) focused on elevating challenges of the profoundly autistic community through advocacy, research advancement, and community support. The organization operates multiple interconnected programs including advocacy initiatives at state and federal levels, research support services, community programs (Sibling Action Network, The Dignity Project, Caregivers Connected), events (Profound Autism Summit, Profound Autism Day, ECHO Autism training), and a Resource Network. These offerings work together to achieve the mission of improving outcomes and recognition for people with profound autism through inclusive research, focused advocacy, and caregiver support.
Differentiator
Problem solved
Functional benefit
Products and services
- Profound Autism Summit A two-day national conference (in-person and virtual) bringing together researchers, clinicians, educators, advocates, and families focused exclusively on the needs of individuals with profound autism across the lifespan.
- Profound Autism Day Annual recognition day on March 17 for people with profound autism and the need for lifelong services and supports, pursued through state proclamation campaigns.
- ECHO Autism: Intense Behavior
Quantifiable outcome
- Achieved official recognition of Profound Autism Day in 15 states in first year of advocacy campaign
- +2 more outcomes
Companies that use Profound Autism Alliance
Customer profileNamed customers5 records
Segments4 records
Ideal customer profiles3 records
Profound Autism Alliance technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Profound Autism Alliance partnerships and signals
Strategic signalPartnerships
Ten partnerships are on record, tiered core and minor.
- Aligning Research to Impact Autism (ARIA)coreARIA is a major initiative to accelerate scientific discovery and create therapeutic opportunities for people with profound autism. The Profound Autism Alliance facilitates the ARIA IMPACT Network, a global clinical trial readiness program. Research institutions including SickKids, Holland Bloorview, Columbia, Weill Cornell, UCLA, and CHLA have received grants through this partnership totaling up to $17.25 million per site.
- The Hospital for Sick Children (SickKids)coreSickKids received up to $17.25 million from ARIA to participate in the IMPACT Network, studying autism and neurodevelopmental conditions. The grant supports a multi-year natural history study and positions the site for future clinical trials for children with profound autism and rare genetic conditions.
- Holland Bloorview Kids Rehabilitation HospitalcoreHolland Bloorview received up to $17.25 million from ARIA as a joint site with SickKids in the IMPACT Network. The collaboration brings together two institutions with long-standing partnership, combining strengths in genomics, biomarker science, neuroimaging, and clinical trials.
- Columbia University Irving Medical CentercoreColumbia received $17.25 million from ARIA to study profound autism, working with collaborators at New York State Psychiatric Institute and Weill Cornell Medicine. The team will contribute to the ARIA IMPACT-Ready study, enrolling children with profound autism over two years.
- Weill Cornell MedicinecoreWeill Cornell Medicine is collaborating with Columbia University Irving Medical Center on the $17.25 million ARIA grant, focusing on pediatric neurology and serving as the clinical lead for the study at NewYork-Presbyterian Komansky Children's Hospital.
- UCLA/Children's Hospital Los Angeles (CHLA)coreUCLA and CHLA received up to $17.25 million as the IMPACT-LA site, one of 12 initial international sites in the ARIA IMPACT Network. UCLA also serves as the Clinical Coordinating Center (with Boston Children's Hospital) providing oversight and infrastructure to all IMPACT sites.
- Nashoba Learning GroupminorSponsor of the Profound Autism Summit 2026, providing support for the national conference focused on profound autism.
- iGiveminorOnline shopping portal that donates a percentage of purchases to Profound Autism Alliance when shoppers register and make purchases through the platform.
- KrogerminorKroger Community Rewards program allows shoppers in 35 states to designate Profound Autism Alliance as their charity of choice, with purchases contributing to the organization.
- CarEasyminorVehicle donation partner allowing donors to contribute cars, trucks, SUVs, motorcycles, RVs, or boats to Profound Autism Alliance instead of selling or trading them in.
Scale indicators3 records
Recent moves7 records
Expansion highlights6 records
Profound Autism Alliance competitors and assessment
Company assessmentBroad incumbents
- Easterseals: Large, established national disability services nonprofit providing direct therapies, workforce programs, and advocacy. Overlaps with the alliance on caregiver supports and policy work, but operates at much greater scale across all disabilities.
Direct peers
- Doug Flutie Jr. Foundation for Autism: Family-founded autism nonprofit funding direct services, research, and community programs across the lifespan. Comparable structure and caregiver-centered orientation, though broader in scope.
- Organization for Autism Research (OAR): Nonprofit that funds applied autism research and provides evidence-based resources to families, teachers, and clinicians. Comparable in combining research funding with caregiver/professional education.
- The Arc of the United States: National advocacy and service organization for people with intellectual and developmental disabilities (IDD), including autism. Comparable as a long-standing policy and community advocacy peer with state chapters.
- Autism Speaks: The largest US autism advocacy and research nonprofit. Directly comparable as a national autism advocacy organization funding research and promoting policy, though broader in scope than the profound-only focus of Profound Autism Alliance.
- Autism Science Foundation: Nonprofit that funds autism research and supports scientists through grants and fellowships. Comparable as a research-funding intermediary, though it spans the full autism spectrum rather than the profound subcategory.
- National Autism Association: Advocacy organization focused specifically on the most severely affected individuals with autism, including those with intense behaviors and high support needs. The closest mission-aligned peer given its emphasis on the profound/severe autism population.
- Autism Society of America: Long-standing national autism advocacy and support organization with affiliate chapters and direct service programs. Comparable in mission and grassroots structure, though it covers the full autism spectrum rather than the profound segment.
- Autism Research Institute: Long-running autism research and advocacy organization, historically focused on biomedical research and physician/provider education. Comparable in bridging research funding with clinical training.
Regional players
- AANE (Asperger/Autism Network): New England-based autism support and education nonprofit serving individuals, families, and professionals. Comparable mission but operates on a regional basis and focuses on a different segment of the autism spectrum.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat5 records
Key risks6 records
Key highlights6 records
Customer concentration
Profound Autism Alliance social profiles
Digital presenceProfound Autism Alliance compliance and trust
Trust signalCompliance3 records
Profound Autism Alliance financial estimates
Financial estimateRevenue estimate
Valuation estimate
Profound Autism Alliance leadership team
Management profileNumber of profiles
Profound Autism Alliance funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Profound Autism Alliance M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Profound Autism Alliance
What does Profound Autism Alliance do?
Profound Autism Alliance is a 501(c)(3) nonprofit that advocates on behalf of individuals with profound autism through state and federal policy campaigns, facilitates participation in clinical research via the ARIA IMPACT Network, and operates caregiver and sibling community programs (Sibling Action Network, Caregivers Connected, Dignity Project, Special Interest Groups). It also runs the annual Profound Autism Summit, Profound Autism Day recognition campaign, and the ECHO Autism: Intense Behavior physician training program.
Is Profound Autism Alliance a public or private company?
Profound Autism Alliance is a private company. It is classified as nonprofit foundation owned and is currently operating.
When was Profound Autism Alliance founded?
Profound Autism Alliance was founded in 2023. It employs 1 to 10 people.
Where is Profound Autism Alliance based?
Profound Autism Alliance is headquartered in Wellesley Hills, United States, in the North America region.
How does Profound Autism Alliance make money?
Four revenue lines are on record. Individual Donations are the primary driver. The others are fundraising Events, corporate Giving Programs and program Funding.
Who are Profound Autism Alliance's main competitors?
Easterseals is listed as a broad incumbent. Direct peers are Doug Flutie Jr. Foundation for Autism, Organization for Autism Research (OAR), The Arc of the United States, Autism Speaks, Autism Science Foundation, National Autism Association, Autism Society of America and Autism Research Institute. AANE (Asperger/Autism Network) is listed as a regional player.
Does Profound Autism Alliance have an API?
No public API is recorded for Profound Autism Alliance.
What industry is Profound Autism Alliance in?
Profound Autism Alliance's product category is Disability Advocacy Services. Its primary akta.pro industry code is EDAKAKAJ, Autism Parent/Caregiver Education & Training (School-Linked), with a secondary code of EDAKAKAL, Autism Teacher Training & Professional Development. Its NAICS code is 8133 and its SIC code is 8300.