TNC Bio
TNC Bio BV is a Dutch biotechnology company that develops and manufactures chemically defined, animal component-free cell culture supplements and media — including XerumFree, CHOiX, and XF ViPro — serving vaccine producers, cell therapy developers, and research institutions globally through a distributor network.
- Company typePrivate
- Founded2011
- HeadquartersEindhoven, Netherlands
- Headcount1–10
- GTM typeB2B
- OfferingHardware or Manufacturing
What TNC Bio does
TNC Bio BV is a privately-held Dutch biotechnology company headquartered at High Tech Campus 29 in Eindhoven, Netherlands, founded in 2011. The company develops and manufactures chemically defined, animal component-free (ACF) cell culture supplements and media used primarily in viral vaccine production, cell therapy manufacturing, and life science research. The product portfolio is anchored by XerumFree™ (XF212), a fully defined serum replacement based on recombinant proteins produced via ACF bacterial processes; CHOiX™, a defined medium for CHO cell bioprocess applications; XF ViPro, a 2025-launched supplement for Vero-cell-based virus production; and the XF Cell Growth Kit family covering endothelial cells, mesenchymal stem cells, and keratinocytes for research-grade use.
The company's core technology rests on fully characterized synthetic and recombinant formulations that eliminate reliance on fetal bovine serum (FBS). Key claimed differentiators include batch-to-batch consistency, full traceability, ultra-low protein content, and supply chain stability derived from raw materials that are not sensitive to world market volatility. The technical positioning directly addresses mounting regulatory pressure across the vaccine and cell therapy industries to remove animal-derived components from production processes due to virus and prion contamination risk.
TNC Bio operates a hybrid go-to-market model: direct B2B sales handle production-scale and custom-volume orders, while a global authorized distributor network covers R&D and routine commercial sales. The distributor footprint spans 35+ countries across Europe, Asia-Pacific, North America, and the Middle East & Africa, with named channel partners including Fisher Scientific, Amsbio, CliniSciences, Westburg, Funakoshi, Caldic, and Stratech. Customer segments are organized horizontally across vaccine producers, cell therapy developers, and life science research institutions, with packaging tailored to both R&D (100/500 ml bottles) and production-scale (bags, vessels) requirements.
TNC Bio firmographics
Firmographics- Name
- TNC Bio
- Legal name
- TNC Bio BV
- Website
- https://tncbio.com
- Company type
- Private
- Founded year
- 2011
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Short description
- TNC Bio BV is a Dutch biotechnology company that develops and manufactures chemically defined, animal component-free cell culture supplements and media — including XerumFree, CHOiX, and XF ViPro — serving vaccine producers, cell therapy developers, and research institutions globally through a distributor network.
- Ownership category
- akta.pro rank
TNC Bio industry classification
Industry- Product category
- Cell Culture Media & Supplements
- NAICS
- Biological Product (except Diagnostic) Manufacturing (325414)
- SIC
- Biological Products, (No Disgnostic Substances) (2836)
- akta.pro primary industry
- Cell Processing & Ancillary Materials (media, cytokines, beads, vectors, disposables) (HLAAABAH)
Keywords
Where TNC Bio is headquartered
LocationHeadquarters
- HQ city
- Eindhoven
- HQ country
- Netherlands
- HQ region
- Europe
Offices1 record
Markets served
TNC Bio business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Supply Chain, Operations, Personnel, Technology or R&D, Marketing or Sales
Revenue model
- Cell Culture Media and Supplements: TNC Bio generates revenue through the sale of chemically defined cell culture supplements and media products including XerumFree, CHOiX, XF ViPro, and various cell growth kits. Products are sold in standard packaging (100ml, 500ml bottles) for R&D and in larger volumes for production purposes.
Go-to-market motion2 records
Distribution channels1 record
Marketing channels1 record
TNC Bio product offering
Product offeringCore offering
TNC Bio manufactures and supplies chemically defined, animal component-free (ACF) cell culture supplements and media products for vaccine production, cell therapy development, and life science research. Its product portfolio includes the XerumFree™ serum replacement, CHOiX™ medium for CHO cells, XF ViPro for virus production with Vero cells, and XF Cell Growth Kits for endothelial cells, mesenchymal stem cells, and keratinocytes. Products are sold in standard packaging for R&D and in custom volumes (bags or vessels) for production-scale bioprocess applications through a global authorized distributor network.
Product overview
TNC Bio offers a portfolio of chemically defined, animal component-free (ACF) cell culture products centered around three core product lines: XerumFree™ serves as the foundational fully defined serum replacement applicable across broad cell culture applications; CHOiX™ provides a specialized fully defined medium optimized for CHO cell bioprocess production of recombinant proteins; and the XF Cell Growth Kit family includes targeted solutions for specific cell types including endothelial cells (XF501), mesenchymal stem cells (MSC505), and keratinocytes (XF-K-500). The most recent addition to the portfolio is XF ViPro, a chemically defined supplement designed for virus production applications with Vero cells. All products share the common value proposition of eliminating animal-derived materials, ensuring batch-to-batch consistency, and enabling more efficient downstream processing compared to traditional serum-based media.
Differentiator
Problem solved
Functional benefit
Brands
- XerumFree: A fully defined additive for serum-free cell culture, avoiding lot-to-lot variations. Chemically defined supplement for a wide range of cell culture practices.
- CHOiX
- XF ViPro
- XF Cell Growth Kits
Products and services
- XerumFree™ (XF212) A fully defined additive for serum-free cell culture that avoids lot-to-lot variations. All components are highly purified, identified chemical compounds of synthetic or recombinant origin, with ultra-low protein content and proteins derived solely from a recombinant bacterial process in ACF media. Used in viral vaccine production, cell therapy, and other serum-free cell culture applications.
- XF ViPro Medium Supplement A chemically defined, animal/human compound free medium supplement designed for use with Vero cells and other cell lines in virus production applications. Eliminates reliance on animal-derived components, enhances batch-to-batch consistency, and reduces downstream processing time. Can be added to any basal medium for flexibility.
- CHOiX™ A fully defined and animal/human component free medium for optimal cell growth and expression of CHO cells, applicable in both R&D projects and manufacturing. The balanced formulation facilitates optimal and high density cell growth as well as high viability of the cells.
- XF501 Defined Endothelial Cell Growth Kit A complete medium for optimal growth of endothelial cells from large vessels. Contains essential and non-essential amino acids, vitamins, organic and inorganic compounds, plus an optimized combination of growth factors, hormones and a growth supplement. All components are free of animal and/or human derived materials. For in vitro research applications only.
- MSC505 Mesenchymal Stem Cell Growth Kit A serum-free mesenchymal stem cell growth kit providing a complete medium for growth of mesenchymal stem cells isolated from bone marrow, cord blood, peripheral blood, fetal liver, lung and adipose tissue. Consists of a basal medium and a supplement. All components are free of animal derived materials. For in vitro research applications only.
- XF-K-500 Keratinocyte Growth Medium Kit A chemically defined, low calcium (0.07 mM) medium formulated for optimal growth of human primary keratinocytes. Contains essential and non-essential amino acids, vitamins, organic and inorganic compounds, hormones, growth factors, and trace minerals. For research use only.
Quantifiable outcome
- Cell output comparable or higher compared to FBS or other undefined media in production environments
Companies that use TNC Bio
Customer profileSegments2 records
Ideal customer profiles2 records
TNC Bio technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature4 records
TNC Bio partnerships and signals
Strategic signalPartnerships
Seven partnerships are on record, tiered standard.
- CliniSciencesstandardEuropean distributor for XerumFree and other TNC Bio products across multiple European countries.
- Fisher ScientificstandardEuropean distributor for XerumFree products, serving customers across Europe and Africa.
- Amsbio Ltd (UK) and Amsbio LLC (USA)standardDistribution partner for XerumFree in United Kingdom and United States markets.
- WestburgstandardBenelux distributor for TNC Bio cell culture products.
- FunakoshistandardJapanese distributor for TNC Bio products including XerumFree.
- CaldicstandardDistribution partner in Italy and Switzerland for TNC Bio products.
- StratechstandardUK-based distribution partner for TNC Bio products.
Scale indicators2 records
Recent moves4 records
Expansion highlights5 records
TNC Bio competitors and assessment
Company assessmentDirect peers
- STEMCELL Technologies: Provider of serum-free media and primary cell culture kits (including mesenchymal stem cell and endothelial cell products) that overlap with TNC Bio's XF Cell Growth Kits portfolio in the research and cell therapy supply market.
- Corning Life Sciences: Corning offers defined and serum-free cell culture media (and vessels) targeting bioprocess and cell therapy customers; directly comparable in addressing ACF manufacturing needs alongside TNC Bio.
- CellGenix: Specialist supplier of GMP-grade raw materials and media for cell and gene therapy manufacturing; peer in the niche of defined, animal-component-free ancillary materials serving cell therapy producers targeted by TNC Bio.
- FUJIFILM Irvine Scientific: Specialist in cell culture media and supplements for cell therapy, gene therapy, and reproductive medicine; comparable ACF and serum-free solutions targeting overlapping biopharma customers to TNC Bio.
Emerging players
- Bio-Techne (R&D Systems): Supplies defined media, cytokines, and growth factors for cell therapy and regenerative medicine research; offers alternative substitute inputs that could compete with TNC Bio's growth kits and supplements in customer formulation decisions.
Broad incumbents
- Merck KGaA / Sigma-Aldrich (Life Science): Sigma-Aldrich/Merck supplies a broad range of cell culture media and reagents, including serum-free and defined formulations; directly competitive with TNC Bio's media portfolio in research and bioproduction.
- Thermo Fisher Scientific (Gibco): Gibco cell culture media is the dominant brand in research and production-scale media for vaccine, cell therapy, and recombinant protein workflows; TNC Bio's ACF portfolio directly overlaps the same customer pain points around FBS elimination and batch consistency.
- Cytiva (HyClone): Cytiva's HyClone media business supplies serum-free and chemically defined media for vaccine and biopharmaceutical production; competes head-on with TNC Bio's XerumFree and CHOiX product lines in the bioprocess media category.
- Sartorius (BIA Separations / Cell Culture Media): Bioprocess supplier offering upstream media, buffers, and process solutions serving vaccine and cell therapy manufacturers; competes with TNC Bio in defined, animal-free media for production environments.
- Lonza Group: Global bioprocess leader offering cell culture media and manufacturing services for vaccines, recombinant proteins, and cell therapies; directly comparable to TNC Bio's ACF media offerings but at vastly larger scale and portfolio breadth.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks6 records
Key highlights6 records
Customer concentration
TNC Bio social profiles
Digital presenceTNC Bio financial estimates
Financial estimateRevenue estimate
Valuation estimate
TNC Bio leadership team
Management profileNumber of profiles
TNC Bio funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
TNC Bio M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about TNC Bio
What does TNC Bio do?
TNC Bio manufactures and supplies chemically defined, animal component-free (ACF) cell culture supplements and media products for vaccine production, cell therapy development, and life science research. Its product portfolio includes the XerumFree™ serum replacement, CHOiX™ medium for CHO cells, XF ViPro for virus production with Vero cells, and XF Cell Growth Kits for endothelial cells, mesenchymal stem cells, and keratinocytes. Products are sold in standard packaging for R&D and in custom volumes (bags or vessels) for production-scale bioprocess applications through a global authorized distributor network.
Is TNC Bio a public or private company?
TNC Bio is a private company. It is classified as unknown and is currently operating.
When was TNC Bio founded?
TNC Bio was founded in 2011. It employs 1 to 10 people.
Where is TNC Bio based?
TNC Bio is headquartered in Eindhoven, Netherlands, in the Europe region.
How does TNC Bio make money?
One revenue line is on record: cell Culture Media and Supplements.
Who are TNC Bio's main competitors?
Direct peers on record are STEMCELL Technologies, Corning Life Sciences, CellGenix and FUJIFILM Irvine Scientific. Bio-Techne (R&D Systems) is listed as an emerging player. Broad incumbents are Merck KGaA / Sigma-Aldrich (Life Science), Thermo Fisher Scientific (Gibco), Cytiva (HyClone), Sartorius (BIA Separations / Cell Culture Media) and Lonza Group.
Does TNC Bio have an API?
No public API is recorded for TNC Bio.
What industry is TNC Bio in?
TNC Bio's product category is Cell Culture Media & Supplements. Its primary akta.pro industry code is HLAAABAH, Cell Processing & Ancillary Materials (media, cytokines, beads, vectors, disposables). Its NAICS code is 325414 and its SIC code is 2836.