Saddle Point Science
- Company typePrivate
- Founded2016
- HeadquartersYork, United Kingdom
- Headcount1–10
- GTM typeB2B
- OfferingSoftware
Saddle Point Science firmographics
Firmographics- Name
- Saddle Point Science
- Legal name
- Saddle Point Science Ltd.
- Website
- https://saddlepointscience.co.uk
- Company type
- Private
- Founded year
- 2016
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Ownership category
- akta.pro rank
Saddle Point Science industry classification
Industry- Product category
- Precision Medicine Analytics Software
- NAICS
- Software Publishers (5132), Scientific Research and Development Services (5417)
- SIC
- Services-Prepackaged Software (7372), Services-Commercial Physical & Biological Research (8731)
- akta.pro primary industry
- Clinical Trial Informatics (EDC/CTMS/eCOA/eTMF) (HLAGAJAM)
- akta.pro secondary industries
- Biostatistics, Statistical Computing & Clinical Programming (SAS/R/Pipelines) (HLACAOAO), Scientific Data Management & Data Platforms (SDMS/Data Lakehouse for R&D) (HLAGAJAC)
Keywords
Where Saddle Point Science is headquartered
LocationHeadquarters
- HQ city
- York
- HQ country
- United Kingdom
- HQ region
- Europe
Offices1 record
Markets served
Saddle Point Science business model
Business model- GTM type
- B2B
- Offering type
- Software
Revenue model
- Software Licensing: Annual licenses for spsSIGNATURE and spsMOSAICS software products sold in multiple tiers (Trial, Collaborator, Public Sector, Commercial). License pricing varies by tier and number of users. All licenses include SaddlePoint DatasetManager free of charge.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Freemium | Pay-as-you-go | Free 2-week trial for single user on Windows |
| Subscription | Annual | Annual license for research collaborators (joint publication) |
| Subscription | Annual | Annual license for public sector institutions |
| Subscription | Annual | Annual license for commercial use |
Go-to-market motion2 records
Distribution channels2 records
Marketing channels4 records
Saddle Point Science product offering
Product offeringCore offering
Saddle Point Science develops and licenses proprietary statistical software products (spsSIGNATURE and spsMOSAICS) that apply Bayesian mathematical methodologies and replica method algorithms to high-dimensional clinical data, enabling researchers to derive reliable risk signatures, identify statistically significant patient subgroups, and conduct survival analysis corrected for informative censoring. The software is licensed in tiered annual subscriptions (Trial, Collaborator, Public Sector, Commercial) and supports research collaborations with academic and clinical partners.
Product overview
Saddle Point Science Ltd is a UK-based data science company offering two proprietary software products for precision medicine: spsSIGNATURE (an automated pipeline for robust risk and treatment response signatures from high-dimensional clinical data using Bayesian regression and the replica method) and spsMOSAICS (a Bayesian latent class modelling pipeline for patient subgroup identification and survival analysis). Both products are available as licensed desktop software for Windows, UNIX/Linux, and MacOS, with optional DatasetManager included for data preparation.
Differentiator
Problem solved
Functional benefit
Brands
- spsSIGNATURE: An automated pipeline for handling high-dimensional clinical data, optimally reducing overfitting to deliver reliable risk and treatment response signatures
- spsMOSAICS
Quantifiable outcome
- Robust risk signatures from AMORIS cohort data analyzing multiple interacting risk factors together - something not feasible at low event numbers with standard regression methods
- +2 more outcomes
Companies that use Saddle Point Science
Customer profileNamed customers7 records
Segments3 records
Ideal customer profiles3 records
Saddle Point Science technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
AI capability6 records
Feature9 records
Saddle Point Science partnerships and signals
Strategic signalPartnerships
Eight partnerships are on record, tiered core and minor.
- King's College London (Translational Oncology and Urology Research)coreMulti-faceted research partnership including: collaboration with TOUR group on prostate cancer risk analysis using AMORIS cohort data (February 2024); HERD project for head and neck cancer recurrence prediction; and LifeArc-funded TACTIC-R project for COVID-19 disease heterogeneity investigation led by Dr Shahram Kordasti. Saddle Point Science leads on Bayesian mathematical model development.
- National Cancer Centre of SingaporecoreHERD project collaboration for head and neck cancer recurrence prediction. Partnership involves King's College London, University College London, University of Cambridge, and National Cancer Centre of Singapore.
- University College LondoncoreHERD project collaboration for head and neck cancer recurrence prediction alongside King's College London, National Cancer Centre of Singapore, and University of Cambridge.
- University of CambridgecoreHERD project collaboration for head and neck cancer recurrence prediction alongside King's College London, National Cancer Centre of Singapore, and University College London.
- Karolinska InstitutetcoreResearch collaboration with King's College London on prostate cancer risk analysis using AMORIS cohort data. Robust epidemiological data analyzed using SaddlePoint-Signature software.
- ReIMAGINE ConsortiumcoreCollaboration applying Saddle Point Science software to prostate cancer data from ReIMAGINE consortium. Early results presented at EAU23 conference in Milan, highlighting need for cutting-edge analysis methods for ambitious clinical trials.
- Eodyne SystemscoreEureka Eurostars PHASE project collaboration for stroke rehabilitation. Saddle Point Science developed algorithms to predict recovery trajectory after stroke, installed on Eodyne's RGS platform for home-based rehabilitation and monitoring.
- Saddle Point Science Europe BVminorEU partner based in Netherlands. Collaborative publication efforts and shared research activities in precision medicine data analysis.
Scale indicators6 records
Recent moves6 records
Expansion highlights3 records
Saddle Point Science competitors and assessment
Company assessmentDirect peers
- Wolfram Research: Mathematica provides advanced statistical, symbolic, and Bayesian functionality marketed to researchers. Competes for the same high-end mathematical statistical analysis workloads in academia.
- Posit (RStudio): Publisher of R/RStudio, the dominant open-source statistical computing environment used in clinical and biomedical research. Competes for the same analytical workflow as Saddle Point Science's licensed packages.
- Cytel: Specialist biostatistics and clinical analytics provider (including East®, Solara®, Studio) serving clinical trial sponsors. Direct competitor in the statistical analysis of clinical trial data for precision medicine.
- Stata: Commercial statistical software widely used for clinical, epidemiological, and survival analyses. Direct competitor to spsSIGNATURE/spsMOSAICS in the statistical-tooling segment for academic and clinical researchers.
- JMP (JMP Statistical Discovery): SAS division selling statistical discovery software used across life sciences and clinical research for visualisation and predictive modelling — directly comparable in user profile and analytical intent.
Broad incumbents
- SAS Institute: Incumbent in clinical trial biostatistics and statistical programming (SAS/STAT, SAS Life Science Analytics). Offers broader analytics suites that overlap with Saddle Point Science's clinical statistics focus.
- MathWorks (MATLAB): Numerical computing platform used by statisticians and engineers for high-dimensional modelling, simulation, and survival analysis — overlapping with the methodological use cases Saddle Point Science addresses.
- DNAnexus: Cloud-based genomics data management and analysis platform serving clinical and translational researchers. Competes for the same precision-medicine analytical workloads at higher enterprise scale.
Emerging players
- LabKey Software: Open-source and commercial platform for managing clinical and translational research data, including integration with biostatistical pipelines. Adjacent competitor for research informatics spend.
- Schrödinger: Computational biology platform combining physics-based modelling with machine learning for life sciences. Adjacent competitor applying advanced statistical/ML methods to pharma and biomedical research workflows.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat4 records
Key risks6 records
Key highlights6 records
Customer concentration
Saddle Point Science social profiles
Digital presenceSaddle Point Science financial estimates
Financial estimateRevenue estimate
Valuation estimate
Saddle Point Science leadership team
Management profileNumber of profiles
Saddle Point Science subsidiaries and ownership
Company hierarchySubsidiaries1 record
Saddle Point Science funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Saddle Point Science M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Saddle Point Science
What does Saddle Point Science do?
Saddle Point Science develops and licenses proprietary statistical software products (spsSIGNATURE and spsMOSAICS) that apply Bayesian mathematical methodologies and replica method algorithms to high-dimensional clinical data, enabling researchers to derive reliable risk signatures, identify statistically significant patient subgroups, and conduct survival analysis corrected for informative censoring. The software is licensed in tiered annual subscriptions (Trial, Collaborator, Public Sector, Commercial) and supports research collaborations with academic and clinical partners.
Is Saddle Point Science a public or private company?
Saddle Point Science is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was Saddle Point Science founded?
Saddle Point Science was founded in 2016. It employs 1 to 10 people.
Where is Saddle Point Science based?
Saddle Point Science is headquartered in York, United Kingdom, in the Europe region.
How does Saddle Point Science make money?
One revenue line is on record: software Licensing.
Who are Saddle Point Science's main competitors?
Direct peers on record are Wolfram Research, Posit (RStudio), Cytel, Stata and JMP (JMP Statistical Discovery). Broad incumbents are SAS Institute, MathWorks (MATLAB) and DNAnexus. Emerging players are LabKey Software and Schrödinger.
Does Saddle Point Science have an API?
No public API is recorded for Saddle Point Science.
What industry is Saddle Point Science in?
Saddle Point Science's product category is Precision Medicine Analytics Software. Its primary akta.pro industry code is HLAGAJAM, Clinical Trial Informatics (EDC/CTMS/eCOA/eTMF), with a secondary code of HLACAOAO, Biostatistics, Statistical Computing & Clinical Programming (SAS/R/Pipelines). Its NAICS code is 5132 and its SIC code is 7372.