Phase Genomics
Phase Genomics develops proximity ligation (Hi-C) technology for ultra-long-range genome sequencing, selling Hi-C kits, cloud-based analysis, and custom services to academic researchers and biopharmaceutical firms for metagenomics, genome scaffolding, and cytogenetics applications.
- Company typePrivate
- Founded2015
- HeadquartersSeattle, United States
- Headcount11–50
- GTM typeB2B
- OfferingHardware or Manufacturing
What Phase Genomics does
Phase Genomics is a Seattle-based, privately held biotechnology company founded in 2015 that develops proximity ligation (Hi-C) technology for ultra-long-range genome sequencing applications spanning metagenomics, plant and animal genomics, cytogenetics, and cancer diagnostics. Its core platform captures physical interactions between DNA sequences co-located in cells in vivo, enabling chromosome-scale genome assemblies, culture-free metagenome deconvolution, and host attribution of mobile genetic elements without reliance on reference databases or statistical assumptions. The company sells the ProxiMeta platform for metagenome deconvolution (with sample-type-specific kits and an included cloud-based Explorer analysis environment) and the Proximo platform for genome scaffolding across human, animal, plant, fungal, and microbial sample types. Complementary algorithms include FALCON-Phase (co-developed with PacBio for haplotype phasing) and ProxiPhage (for viral genome reconstruction and host attribution), with newer programs OncoTerra (AI-based cancer diagnostics) and CytoTerra (cytogenomics) extending into clinical-adjacent verticals.
The company operates a hybrid business model combining product-led kit sales through its website, customized fee-for-service projects (library prep, sequencing, and bioinformatics), and grant-funded R&D. Pricing is not publicly disclosed; ProxiMeta kits include free cloud-based analysis while Proximo kits are sold with or without analysis services and service projects are quoted individually. Distribution is primarily direct in the US with an international distributor network covering 11 countries across APAC, Oceania, and Europe (e.g., Sapphire Bioscience, Nucleus Biotech, Filgen, Phyzen). QIAGEN distributes Hi-C epigenetics products in the US under a 2020 channel partnership. Customers are predominantly academic and research institutions (named users include Auburn/HudsonAlpha, Iowa State, BYU, University of Bern, and Ohio State) alongside biopharmaceutical firms, with products labeled "For Research Use Only." Capital formation has been almost entirely non-dilutive, with cumulative disclosed grant funding exceeding $16 million from NIH, the Bill & Melinda Gates Foundation, and the National Cancer Institute between 2017 and 2024. The company employs 11-50 people and is led by founder/CEO Ivan Liachko, CTO Shawn Sullivan, COO Kayla Young, VP R&D Stephen Eacker, and CBO David Shoultz (appointed October 2024).
Phase Genomics firmographics
Firmographics- Name
- Phase Genomics
- Legal name
- Phase Genomics, Inc.
- Website
- https://phasegenomics.com
- Company type
- Private
- Founded year
- 2015
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Phase Genomics develops proximity ligation (Hi-C) technology for ultra-long-range genome sequencing, selling Hi-C kits, cloud-based analysis, and custom services to academic researchers and biopharmaceutical firms for metagenomics, genome scaffolding, and cytogenetics applications.
- Ownership category
- akta.pro rank
Phase Genomics industry classification
Industry- Product category
- Genomics Research Reagents and Services
- NAICS
- In-Vitro Diagnostic Substance Manufacturing (325413), Medical Laboratories (621511), Research and Development in Biotechnology (except Nanobiotechnology) (541714)
- SIC
- Laboratory Analytical Instruments (3826), In Vitro & In Vivo Diagnostic Substances (2835), Services-Medical Laboratories (8071)
- akta.pro primary industry
- Molecular Biology & Genomics Instruments (PCR/qPCR, Sequencing, Microarrays) (HLAGAIAF)
- akta.pro secondary industries
- Genomics & Molecular Diagnostics (Trial Support) (HLAGAEAD), Genetic & Genomic Testing (germline, somatic, carrier, pharmacogenomics) (HLAAALAD)
Keywords
Where Phase Genomics is headquartered
LocationHeadquarters
- HQ city
- Seattle
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Phase Genomics business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Technology or R&D, Personnel, Operations, Marketing or Sales, Supply Chain
Revenue model
- Hi-C Kit Sales: Sale of proximity ligation library preparation kits (Proximo and ProxiMeta) for various sample types including human, animal, plant, fungi, and microbes. Kits include reagents for library prep but do not include sequencing costs.
- Analysis Service Projects: Customized service projects including Proximity ligation and/or shotgun library prep, Hi-C library QC, NGS services, FALCON-Phase haplotype phasing, 3D conformational mapping, and de novo genome assembly and annotation.
- Cloud-based Analysis Platform: ProxiMeta kits include free cloud-based ProxiMeta Analysis on the web-based platform. Proximo analysis services available separately for genome scaffolding projects.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| One time/ perpetual license | Pay-as-you-go | ProxiMeta 8-sample kit with included analysis |
| One time/ perpetual license | Pay-as-you-go | Proximo Hi-C 2-pack kits |
| Other | Multi-year contract | Customized full-service projects |
Go-to-market motion2 records
Distribution channels3 records
Marketing channels6 records
Phase Genomics product offering
Product offeringCore offering
Phase Genomics develops and sells proprietary proximity ligation (Hi-C) library preparation kits and bioinformatics platforms that enable ultra-long-range genome sequencing for metagenome deconvolution, chromosome-scale genome scaffolding, haplotype phasing, and cytogenomics. Its core offerings include the Proximo and ProxiMeta kit platforms (with sample-type-specific formulations), cloud-based ProxiMeta Explorer analysis, and customized end-to-end service projects for academic, biopharmaceutical, and agricultural biotechnology customers.
Product overview
Phase Genomics offers a platform-plus-products architecture centered on ultra-long-range genome sequencing technology powered by proximity ligation (Hi-C). The core products include the ProxiMeta™ Platform for metagenome deconvolution and the Proximo™ Platform for genome scaffolding, both supported by sample-type-specific Hi-C library preparation kits. These platforms are complemented by the FALCON-Phase haplotype phasing algorithm (co-developed with PacBio), the ProxiPhage algorithm for viral analysis, and the cloud-based ProxiMeta Explorer for data analysis. In June 2025, the company expanded its offerings with ProxiMeta Starter and Elite Bundles to provide tiered access to genome-resolved metagenomics.
Differentiator
Problem solved
Functional benefit
Brands
- ProxiMeta: Metagenome Deconvolution Platform for microbiome research, enabling high-quality genome assembly from complex microbial communities without culturing
- Proximo
- CytoTerra
- FALCON-Phase
- OncoTerra
- ProxiPhage
Products and services
- ProxiMeta Platform A complete sample-to-insights metagenome deconvolution platform that combines proximity ligation (Hi-C) data with shotgun sequencing to assemble high-quality metagenomes and associate mobile genetic elements (plasmids, phages, antibiotic resistance genes) with their microbial hosts without culturing. Designed for microbiome researchers, infectious disease investigators, and biopharmaceutical groups needing strain-level resolution of complex microbial communities.
- Proximo Platform Genome scaffolding platform that employs proximity ligation (Hi-C) data to orient and order contigs into chromosome-scale, reference-quality genome assemblies. Available in five sample-type-specific kit formulations (human, animal, plant, fungal, microbe) and used by researchers building reference genomes, resolving haplotypes, and detecting structural variants across organisms.
- Proximo Hi-C Kit (Human) Proximity ligation library preparation kit optimized for human samples, including reagents for four library preps and dual-indexed libraries compatible with Illumina and Element sequencing platforms. Used by human genomics, cytogenetics, and clinical research laboratories for chromosome-scale genome assembly and haplotype phasing.
- Proximo Hi-C Kit (Animal) Proximity ligation library preparation kit optimized for animal samples, including reagents for two library preps and dual-indexed libraries compatible with Illumina and Element sequencing platforms. Designed for various vertebrate and invertebrate tissue types used in animal genomics and reference genome projects.
- Proximo Hi-C Kit (Plant) Proximity ligation library preparation kit optimized for plant samples, including additional wash steps for samples rich in polyphenols and reagents for two library preps. Designed for plant genomics, polyploid crop improvement, and reference genome assembly of species with complex genomes.
- Proximo Hi-C Kit (Fungal) Proximity ligation library preparation kit optimized for fungal samples, including reagents for two library preps and designed to handle challenging fungal genomic elements such as repeats and structural variants. Used by fungal genomics and fungal pathogen researchers.
- Proximo Hi-C Kit (Microbe) Proximity ligation library preparation kit optimized for microbial samples, including reagents for two library preps and designed for bacterial and archaeal genome applications. Used by microbiology, environmental genomics, and microbiome researchers.
- FALCON-Phase Haplotype phasing algorithm co-developed with PacBio that combines Hi-C data with long-read sequencing (FALCON-Unzip or purge_haplotigs) to produce two true phased sets of contigs for diploid organisms, achieving >96% contig phasing accuracy. Available through joint commercialization with PacBio and used by researchers building diploid reference genomes.
- ProxiPhage Algorithm available through the ProxiMeta platform that augments metagenomic analysis with Hi-C linkage information to enable specific and sensitive host attribution of DNA viruses (phages) and reconstructs higher-quality bacterial and viral genomes without culturing. Used by microbiome, phage, and infectious disease researchers.
- ProxiMeta Explorer Interactive, cloud-based genome-resolved metagenomic analysis platform included free with ProxiMeta kit purchases. Enables taxonomic annotation, abundance calculations, customizable analyses, and genome tracking across samples for researchers performing metagenomic studies.
- ProxiMeta Starter Bundle Entry-level product bundle launched in June 2025 to expand access to genome-resolved metagenomics research, designed for researchers beginning metagenomic studies with comprehensive ProxiMeta kit and analysis capabilities.
- ProxiMeta Elite Bundle Premium product bundle launched in June 2025 offering comprehensive access to deep metagenomic research capabilities for advanced researchers, including expanded ProxiMeta kit reagents and cloud analysis features.
- Customized Genomic Analysis Service Projects Customized full-service projects including proximity ligation and/or shotgun library preparation, Hi-C library QC, NGS sequencing services, FALCON-Phase haplotype phasing, 3D conformational mapping, and de novo genome assembly and annotation. Sold by quote and tailored to enterprise and academic customer needs.
Quantifiable outcome
- Detects organisms at 0.02% abundance (1 in 5,000 cells) in complex samples
- +3 more outcomes
Companies that use Phase Genomics
Customer profileNamed customers5 records
Segments3 records
Ideal customer profiles3 records
Phase Genomics technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration4 records
Feature5 records
Phase Genomics partnerships and signals
Strategic signalPartnerships
Nine partnerships are on record, tiered major, core and minor.
- QIAGENmajorStrategic partnership to bring Hi-C epigenetics solutions to the US market. QIAGEN distributes Phase Genomics proximity ligation products.
- Pacific Biosciences (PacBio)coreCo-development of FALCON-Phase software that combines PacBio long-read sequencing with Hi-C data to produce highly contiguous phased diploid genome assemblies. Joint commercialization of the software.
- Integrated Sciences Pty LtdminorAuthorized distributor for Phase Genomics products in Australia.
- Sapphire BioscienceminorAuthorized distributor for Phase Genomics products in Australia and New Zealand.
- Nucleus Biotech GmbHminorAuthorized distributor for Phase Genomics products in Austria, Germany, and Switzerland.
- Filgen, Inc.minorAuthorized distributor for Phase Genomics products in Japan.
- PhyzenminorAuthorized distributor for Phase Genomics products in Korea.
- Genosys Inc./Total Genomics SolutionminorAuthorized distributor for Phase Genomics products in Malaysia and Singapore.
- SciencewerkeminorAuthorized distributor for Phase Genomics products in Indonesia.
Scale indicators5 records
Recent moves6 records
Expansion highlights6 records
Phase Genomics competitors and assessment
Company assessmentDirect peers
- Dovetail Genomics (Cantata Bio): Dovetail, now part of Cantata Bio, is the original commercializer of Hi-C proximity ligation kits for genome scaffolding and is Phase Genomics' most direct competitor in metagenome deconvolution and de novo assembly applications.
- 10x Genomics: 10x Genomics offers linked-read and single-cell kits that compete with Hi-C-based scaffolding and metagenomic phasing for similar academic and biopharma customers.
- Bionano Genomics: Bionano's optical genome mapping is an alternative approach to chromosome-scale scaffolding and structural variant detection, serving the same cytogenomics and de novo assembly workflows as Proximo.
Broad incumbents
- Pacific Biosciences (PacBio): PacBio is both a sequencing-platform partner (co-developer of FALCON-Phase with Phase Genomics) and a broader incumbent whose long-read chemistry increasingly competes with Hi-C for assembly and phasing use cases.
- Illumina: Illumina is the dominant short-read sequencing platform onto which Phase Genomics' kits are designed to run; it is also a broad incumbent that could launch competing proximity-ligation or linked-read chemistries.
- QIAGEN: QIAGEN is a US distribution partner for Phase Genomics' Hi-C products and also a broad sample-prep incumbent whose catalog of nucleic acid reagents overlaps with kit-based genomic workflows.
- Oxford Nanopore Technologies: Oxford Nanopore offers long-read sequencing as an alternative platform to the Hi-C + short-read or Hi-C + PacBio workflows Phase Genomics supports, particularly for de novo assembly and structural variant detection.
- Bio-Rad Laboratories: Bio-Rad is a broad life-science tools and reagents incumbent with droplet-based and ddPCR technologies that intersect with Phase Genomics' sample-prep and genomic-analysis workflows in academic and clinical research.
Emerging players
- Element Biosciences: Element is an emerging sequencing-platform vendor whose AVITI system is explicitly supported by Proximo kits, positioning it as both a complementary platform and a potential competitor in library-prep ecosystems.
- KromaTiD: KromaTiD develops cytogenomic and chromatin-conformation tools that overlap with Phase Genomics' CytoTerra platform, targeting similar structural-variant and chromosomal-abnormality applications.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat6 records
Key risks5 records
Key highlights6 records
Customer concentration
Phase Genomics social profiles
Digital presencePhase Genomics compliance and trust
Trust signalCompliance1 record
Phase Genomics financial estimates
Financial estimateRevenue estimate
Valuation estimate
Phase Genomics leadership team
Management profileNumber of profiles
Profiles11 records
Phase Genomics funding detail
Funding detailFunding overview
Funding rounds10 records
Investors8 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Phase Genomics M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Phase Genomics
What does Phase Genomics do?
Phase Genomics develops and sells proprietary proximity ligation (Hi-C) library preparation kits and bioinformatics platforms that enable ultra-long-range genome sequencing for metagenome deconvolution, chromosome-scale genome scaffolding, haplotype phasing, and cytogenomics. Its core offerings include the Proximo and ProxiMeta kit platforms (with sample-type-specific formulations), cloud-based ProxiMeta Explorer analysis, and customized end-to-end service projects for academic, biopharmaceutical, and agricultural biotechnology customers.
Is Phase Genomics a public or private company?
Phase Genomics is a private company. It is classified as venture growth investor backed and is currently operating.
When was Phase Genomics founded?
Phase Genomics was founded in 2015. It employs 11 to 50 people.
Where is Phase Genomics based?
Phase Genomics is headquartered in Seattle, United States, in the North America region.
How does Phase Genomics make money?
Three revenue lines are on record. Hi-C Kit Sales are the primary driver. The others are analysis Service Projects and cloud-based Analysis Platform.
Who are Phase Genomics's main competitors?
Direct peers on record are Dovetail Genomics (Cantata Bio), 10x Genomics and Bionano Genomics. Broad incumbents are Pacific Biosciences (PacBio), Illumina, QIAGEN, Oxford Nanopore Technologies and Bio-Rad Laboratories. Emerging players are Element Biosciences and KromaTiD.
Does Phase Genomics have an API?
No public API is recorded for Phase Genomics.
What industry is Phase Genomics in?
Phase Genomics's product category is Genomics Research Reagents and Services. Its primary akta.pro industry code is HLAGAIAF, Molecular Biology & Genomics Instruments (PCR/qPCR, Sequencing, Microarrays), with a secondary code of HLAGAEAD, Genomics & Molecular Diagnostics (Trial Support). Its NAICS code is 325413 and its SIC code is 3826.