rosetta design group
Rosetta Design Group is a private computational macromolecular modeling consulting firm based in Albuquerque, NM, providing contract R&D, software support, and training in protein design and bioinformatics to biotech and pharma clients using the Rosetta Suite and modern AI tools.
- Company typePrivate
- Founded2007
- HeadquartersBurlington, United States
- Headcount—
- GTM typeB2B
- OfferingServices
What rosetta design group does
Rosetta Design Group LLC is a private computational macromolecular modeling and bioinformatics consulting firm founded in 2007 and headquartered in Albuquerque, New Mexico. The company operates as a small, specialized provider of contract R&D, scientific consulting, software support, and on-site training to pharmaceutical, biotech, and academic clients engaged in protein design, structure prediction, and computational biology. Its customer roster publicly names Fable Therapeutics, Kyowa Kirin, and GMA (Genentech), and the firm is a member of the Rosetta Commons research consortium alongside more than 100 academic and industry laboratories.
The firm's service portfolio is built around the Rosetta Suite — a long-standing macromolecular modeling toolkit — and modern AI-driven protein design tools including RoseTTAFold, RFDiffusion, and ProteinMPNN. Rosetta Design Group functions as an external services arm of the Rosetta Commons, applying both classical Rosetta energy functions and state-of-the-art deep learning methods to client projects spanning protein structure prediction, de novo protein and binder design, enzyme engineering, antibody design, and molecular dynamics. The firm maintains a relationship with the University of Washington's CoMotion office, the technology-transfer channel through which much of the Rosetta ecosystem is anchored.
Rosetta Design Group operates on a fee-for-services, work-for-hire commercial model under which the client retains all intellectual property generated during an engagement. Pricing is project-based, with contracts structured as multi-year arrangements. Founder Xavier Ambroggio continues to serve in an advisory capacity, while David Nannemann, who joined in 2020, has served as Managing Member since 2021, formalizing a planned leadership transition.
rosetta design group firmographics
Firmographics- Name
- rosetta design group
- Legal name
- Rosetta Design Group LLC
- Website
- https://rosettadesigngroup.com
- Company type
- Private
- Founded year
- 2007
- Operating status
- Operating
- Short description
- Rosetta Design Group is a private computational macromolecular modeling consulting firm based in Albuquerque, NM, providing contract R&D, software support, and training in protein design and bioinformatics to biotech and pharma clients using the Rosetta Suite and modern AI tools.
- Ownership category
- akta.pro rank
rosetta design group industry classification
Industry- Product category
- Computational Biology / Protein Design Services
- NAICS
- Research and Development in Biotechnology (except Nanobiotechnology) (541714), Scientific Research and Development Services (5417)
- SIC
- Services-Commercial Physical & Biological Research (8731), Services-Computer Programming Services (7371)
- akta.pro primary industry
- Protein Engineering & Directed Evolution Platforms (enzyme/therapeutic protein optimization) (HLAAAIAC)
- akta.pro secondary industries
- AI/ML-Enabled Biologic Discovery Platforms (computational design, in silico screening) (HLAAAIAE), AI/ML Platforms for Drug Discovery & Experiment Optimization (HLAGAJAO)
Keywords
Where rosetta design group is headquartered
LocationHeadquarters
- HQ city
- Burlington
- HQ country
- United States
- HQ region
- North America
Offices2 records
Markets served
rosetta design group business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Technology or R&D, Operations, Marketing or Sales, Others
Revenue model
- Contract R&D Services: Primary revenue stream. Tailored contract research and development in computational macromolecular modeling and protein design. Projects are scoped to meet unique client needs with full IP assignment to client (no royalties or reach-through).
- Consulting Services: Expert consulting in computational macromolecular modeling and bioinformatics. Provides guidance on specific projects or ongoing support for research optimization.
- Rosetta Software Support Services: Dedicated support services for navigating the Rosetta Macromolecular Modeling Suite. Includes troubleshooting, workflow optimization, and leveraging Rosetta's full potential.
- Training Services: Custom training programs in macromolecular modeling with focus on industry licensees of Rosetta Software Suite. On-site delivery options with instructional presentations and hands-on tutorials.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Other | Multi-year contract | Quote-based fee-for-service engagement |
Go-to-market motion2 records
Distribution channels2 records
Marketing channels5 records
rosetta design group product offering
Product offeringCore offering
Rosetta Design Group provides tailored contract research and development, consulting, software support, and training in computational macromolecular modeling, protein design, and engineering. The firm leverages the Rosetta Macromolecular Modeling Suite alongside modern deep-learning tools (RoseTTAFold, RFDiffusion, ProteinMPNN) to deliver custom protein engineering solutions for applications ranging from enzymes and antibodies to peptides and small-molecule binders. Engagements run on a fee-for-service, work-for-hire basis with full IP assignment to the client.
Product overview
Rosetta Design Group is a service-based company offering a portfolio of four interconnected professional services in computational protein modeling and design. The core offering is Contract R&D Services, which provides tailored research and development using the Rosetta Suite and modern AI/ML tools. This is complemented by Hourly Consulting Services for strategic guidance, Rosetta Software Support Services for technical assistance with the Rosetta platform, and Macromolecular Modeling Training for skill development. Together, these services address the complete lifecycle of protein design projects—from initial modeling and design through software implementation and team capability building.
Differentiator
Problem solved
Functional benefit
Products and services
- Contract R&D Services
- Hourly Consulting Services
- Rosetta Software Support Services
- Macromolecular Modeling Training
Quantifiable outcome
- Full IP assignment for designed sequences - eliminates IP reach-through concerns
Companies that use rosetta design group
Customer profileNamed customers3 records
Segments2 records
Ideal customer profiles2 records
rosetta design group technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
AI capability3 records
Feature4 records
rosetta design group partnerships and signals
Strategic signalPartnerships
Four partnerships are on record, tiered core and foundational.
- Rosetta CommonscoreMember institution of the Rosetta Commons, a consortium of international researchers from universities, government labs, and industry. The consortium aims to further research and development of algorithms for macromolecular modeling and design, including the Rosetta Software Suite. Rosetta Design Group serves as a bridge between industry scientists and the academic community, facilitating collaborations and contributing to continuous improvement of Rosetta software.
- University of Washington (CoMotion)coreRosetta Software Suite is available for download through University of Washington's CoMotion platform. Rosetta Design Group serves as a commercial support partner for industry users of the Rosetta Software Suite.
- Brian Kuhlman Lab (UNC Chapel Hill)foundationalFounder Xavier Ambroggio was a postdoctoral researcher in Brian Kuhlman's lab. Dr. Kuhlman completed postdoctoral work in David Baker's lab at University of Washington. Deep historical connection to foundational Rosetta development.
- Jens Meiler Lab (Vanderbilt University)foundationalManaging Member David Nannemann trained under Prof. Jens Meiler at Vanderbilt University. Co-founder connection to foundational Rosetta development community.
Scale indicators3 records
Recent moves6 records
Expansion highlights4 records
rosetta design group competitors and assessment
Company assessmentDirect peers
- Cyrus Biotechnology: Cyrus Biotechnology is the closest direct peer: a Seattle-based spinout from the David Baker lab offering protein design and engineering services using the Rosetta Suite combined with modern ML tools. Operates a similar work-for-hire model for biotech and pharma clients.
Broad incumbents
- Schrödinger, Inc. Public computational chemistry and biology platform company offering software and services across molecular design, including biologics modeling. Broad incumbent in computational drug discovery with overlapping protein design capabilities and much larger scale.
- Isomorphic Labs: Alphabet-owned AI drug discovery company applying DeepMind's AlphaFold to drug design. A broad incumbent with deep capital and proprietary AI infrastructure competing for the same pharma protein design budgets as Rosetta Design Group.
- Recursion Pharmaceuticals: Public AI-driven drug discovery company combining high-throughput biology with computational methods. A broad incumbent operating across multiple therapeutic areas with substantial capital and platform tooling that overlaps in target ID and protein design services.
- Insilico Medicine: AI-driven drug discovery company combining generative biology, chemistry, and clinical development. A broad incumbent offering end-to-end discovery services that overlap with RDG's contract R&D in target ID and protein design.
- Atomwise: AI drug discovery company focused on small molecule design with AtomNet platform. A broader incumbent in computational drug discovery partnering with pharma, indirectly competing for the same R&D budgets as Rosetta Design Group.
Emerging players
- Generate Biomedicines: Flagship Pioneering-backed generative AI protein design company building proprietary platforms for de novo therapeutic proteins. An emerging competitor in AI-driven protein engineering with significantly more capital and proprietary tooling.
- Cradle Bio: Venture-backed startup building generative AI tools for protein engineering, sold to biotech and industrial biotech clients. Emerging platform competitor with self-service tooling that could displace outsourced protein design services.
- Profluent Bio: AI protein design company developing foundation models for protein generation, founded by researchers from the Baker lab ecosystem. Emerging competitor applying similar academic methods as a software platform rather than a services business.
- EvolutionaryScale: AI startup founded by the creators of RFDiffusion/ESMFold building frontier protein language models. Directly competes with the underlying methods RDG applies, packaged as a platform offering for biotech and pharma.
Market position
Strengths4 records
Weaknesses5 records
Competitive moat4 records
Key risks5 records
Key highlights6 records
Customer concentration
rosetta design group social profiles
Digital presencerosetta design group financial estimates
Financial estimateRevenue estimate
Valuation estimate
rosetta design group leadership team
Management profileNumber of profiles
Profiles2 records
rosetta design group funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
rosetta design group M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about rosetta design group
What does rosetta design group do?
Rosetta Design Group provides tailored contract research and development, consulting, software support, and training in computational macromolecular modeling, protein design, and engineering. The firm leverages the Rosetta Macromolecular Modeling Suite alongside modern deep-learning tools (RoseTTAFold, RFDiffusion, ProteinMPNN) to deliver custom protein engineering solutions for applications ranging from enzymes and antibodies to peptides and small-molecule binders. Engagements run on a fee-for-service, work-for-hire basis with full IP assignment to the client.
Is rosetta design group a public or private company?
rosetta design group is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was rosetta design group founded?
rosetta design group was founded in 2007.
Where is rosetta design group based?
rosetta design group is headquartered in Burlington, United States, in the North America region.
How does rosetta design group make money?
Four revenue lines are on record. Contract R&D Services are the primary driver. The others are consulting Services, rosetta Software Support Services and training Services.
Who are rosetta design group's main competitors?
Cyrus Biotechnology is listed as a direct peer. Broad incumbents are Schrödinger, Inc., Isomorphic Labs, Recursion Pharmaceuticals, Insilico Medicine and Atomwise. Emerging players are Generate Biomedicines, Cradle Bio, Profluent Bio and EvolutionaryScale.
Does rosetta design group have an API?
No public API is recorded for rosetta design group.
What industry is rosetta design group in?
rosetta design group's product category is Computational Biology / Protein Design Services. Its primary akta.pro industry code is HLAAAIAC, Protein Engineering & Directed Evolution Platforms (enzyme/therapeutic protein optimization), with a secondary code of HLAAAIAE, AI/ML-Enabled Biologic Discovery Platforms (computational design, in silico screening). Its NAICS code is 541714 and its SIC code is 8731.