Human Longevity

What Human Longevity does

Human Longevity is a San Diego-based precision longevity company founded in 2013 by J. Craig Venter — the scientist who led the first sequencing of the human genome. The company delivers AI-powered preventive health assessments that combine clinical-grade whole genome sequencing (6.4 billion base pairs at 30x coverage), 3T whole-body MRI, NeuroQuant brain volumetrics, cardiac imaging, and 120+ blood biomarkers in a single integrated visit. Its Longevity AI platform cross-references genomic, phenotypic, imaging, and longitudinal biomarker data to surface disease risk across cancer, cardiovascular disease, neurodegeneration, and metabolic conditions — often years before symptoms emerge.

The company's commercial offering is structured in three tiers: Genomics for All ($599 one-time whole genome sequencing), Executive Health ($8,000/year comprehensive diagnostic program for adults under 65), and 100+ Care ($12,000/year ongoing longevity program for adults 65 and older). The business also generates standalone $3,900 whole-body MRI scans. Revenue mechanics combine one-time consumer genomics purchases with high-margin annual subscriptions, sold via a direct-to-consumer website channel, complimentary consultation booking, physician referrals, and a growing mobile app presence on Apple App Store. Operations span two California clinic locations (San Diego flagship opened 2015, South San Francisco opened 2022), with explicit plans for international expansion into Europe, Asia, Saudi Arabia, and the GCC funded by the September 2024 $39.8M Series B.

The company has invested $600M+ into building what it describes as one of the world's largest private genomic databases — 75,000+ genomes sequenced, 400M+ genetic variants cataloged, and 14,000+ health assessments completed across 10,000+ clients. In May 2026 it spun out Human Life Foundation Models (HLFM) as a joint subsidiary with Insilico Medicine to build longevity-specific AI foundation models. The Scientific Advisory Board now includes Nobel Laureates Geoffrey Hinton and Michael Levitt alongside biogerontologist Aubrey de Grey. Backed by TVM Capital Healthcare, Panacea Venture, and Emerging Technology Partners, the company operates as a privately held venture-backed entity following a steep secondary-market valuation reset from approximately $1.6B to $310M.

Name

Human Longevity

Legal name

Human Longevity Inc.

Website

https://humanlongevity.com

Company type

Private

Founded year

2013

Operating status

Operating

Headcount range

51–100 employees

Short description

Human Longevity is a San Diego-based precision longevity company offering AI-powered whole genome sequencing, 3T whole-body MRI, and multi-omic health assessments to affluent consumers and executives through tiered subscription programs and two California clinics.

Ownership category

akta.pro rank

Product category

Precision Longevity Diagnostics

NAICS

Diagnostic Imaging Centers (621512)

akta.pro primary industry

Medical Wellness & Longevity (Health Screening, Biohacking, Anti-aging Programs) (THAJAHAI)

akta.pro secondary industries

Clinical Data Repositories (CDR) & Longitudinal Patient Records (HLACAIAH), Chronic Disease & Complex Care Management (Geriatrics) (HLADALAC), Chronic Disease Management Pathways (e.g., diabetes, CHF, COPD) (HLACAGAG)

Keywords

• Whole genome sequencing
• Precision longevity medicine
• Preventive health diagnostics
• Whole body MRI screening
• AI health risk prediction

Headquarters

HQ city

San Diego

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Technology or R&D, Operations, Infrastructure, Marketing or Sales

Revenue model

1. Precision Health Programs: Annual subscription programs offering comprehensive health assessments including whole genome sequencing, whole-body MRI, hundreds of biomarkers, cardiac imaging, and physician consultations. Programs include Executive Health ($8,000/year) and 100+ Care ($12,000/year).
2. Whole Genome Sequencing Kit: One-time purchase of clinical-grade whole genome sequencing (6.4 billion base pairs) with AI interpretation at $599. Includes 1-year HLI AI App subscription, annual re-analysis as science advances, and lifetime data access.
3. Standalone Whole Body MRI: Single scan service priced at $3,900 for comprehensive whole-body MRI screening using 3T technology with expert radiologist review.

Pricing tiers

Go-to-market motion2 records

Distribution channels4 records

Marketing channels7 records

Core offering

Human Longevity delivers clinical-grade whole genome sequencing, whole-body 3T MRI imaging, and 120+ biomarker assessments through tiered annual membership programs (Executive Health at $8,000/year and 100+ Care at $12,000/year) plus a standalone $599 whole genome kit. The company integrates multi-omic data with an AI-powered Longevity AI platform to predict disease risk across cancer, cardiovascular, metabolic, and neurodegenerative conditions years before symptoms appear.

Product overview

Human Longevity offers a three-tiered precision health platform centered on clinical-grade whole genome sequencing, advanced imaging, and AI-powered health risk prediction. The entry point is Genomics for All ($599) providing standalone whole genome sequencing with AI interpretation. Executive Health ($8,000/year) adds comprehensive single-day diagnostics including whole-body 3T MRI, cardiac imaging, and 120+ biomarkers. 100+ Care ($12,000/year) extends this with continuous monitoring, quarterly physician follow-ups, and GRAIL liquid biopsy. All tiers integrate with the Longevity AI app and Personal Longevity Intelligence Platform for ongoing health management. The ecosystem includes the $1M Cancer Prevention Pledge, DoctorsForMe AI physician matching, and the newly launched Human Life Foundation Models research initiative with Insilico Medicine.

Differentiator

Problem solved

Functional benefit

Brands

• Human Life Foundation Models (HLFM): AI foundation model longevity platform subsidiary created in collaboration with Insilico Medicine
• DoctorsForMe
• Longevity AI App
• 100+ Longevity Care

Products and services

• Genomics for All Clinical-grade whole genome sequencing at $599 analyzing all 6.4 billion base pairs with AI-powered interpretation, pharmacogenomics for 200+ medications, disease risk insights, and carrier status. Includes 1-year Longevity AI App subscription, annual re-analysis, and lifetime data access. Delivered as at-home saliva kit with 4-6 week turnaround.
• Executive Health Comprehensive single-day health assessment at $8,000 annually combining whole genome sequencing, whole-body 3T MRI, 120+ blood biomarkers, cardiac imaging (echocardiogram, EKG, CT calcium score), DEXA, and expert physician review. For individuals under 65. Includes the $1M Cancer Prevention Pledge.
• 100+ Care Ongoing physician-led longevity care program at $12,000 annually for individuals 65 and older. Includes everything in Executive Health plus continuous glucose monitoring, Zio patch cardiac monitoring, GRAIL liquid biopsy, cardiac MRI, low-dose CT of lung, AMRA body composition, and quarterly physician follow-ups.
• Whole Body MRI Standalone 3T whole-body MRI scan at $3,900 with NeuroQuant brain analysis, enhanced prostate screening, female reproductive imaging, cardiac/vascular assessment, and liver/abdominal screening. No radiation. 60-minute scan, FSA/HSA eligible.
• $1M Cancer Prevention Pledge Financial guarantee backing the comprehensive cancer screening program. If an eligible active member develops late-stage pancreatic, prostate, ovarian, lung, or colon cancer, HLI contributes up to $1,000,000 toward treatment, clinical navigation, and expert oncology consultation.

Quantifiable outcome

• 150GB+ of health data collected in a single visit
• +3 more outcomes

Named customers5 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability11 records

Feature5 records

Partnerships

16 partnerships are on record, tiered supporting and core.

• GRAILsupportingTechnology or Integration · 22 June 2026Multi-cancer early detection (MCED) blood test provider for cancer screening within the 100+ Care program.
• Insilico MedicinecoreStrategic or Co-development Partner · 26 May 2026Multi-million-dollar AI co-development collaboration to build the industry's first large-scale foundation models dedicated to human longevity science. Combines Insilico's multimodal foundation model development expertise and MMAI Gym framework with Human Longevity's comprehensive multi-omic, imaging, and longitudinal health datasets. A new subsidiary, Human Life Foundation Models (HLFM), was created for this partnership.
• Geoffrey HintoncoreOthers · 10 April 2026Nobel Prize-winning AI pioneer (2024 Nobel Prize in Physics) joined as Scientific Advisor to guide AI strategy for disease-risk prediction and early detection platforms. Will help develop next-generation predictive models using HLI's comprehensive longitudinal dataset spanning genomics, imaging, and multi-omic biomarkers.
• LEV FoundationcoreStrategic or Co-development Partner · 26 March 2026Strategic research collaboration to study blood samples from centenarians (100+) and supercentenarians (110+) using Human Longevity's AI-driven precision longevity platform combined with LEV Foundation's anti-aging research focus. Multi-omic analysis aims to identify biomarkers and molecular pathways associated with exceptional longevity for future diagnostics, therapeutics, and preventive strategies.
• Aubrey de GreycoreOthers · 26 March 2026LEV Institute President and Chief Science Officer, and leading biogerontologist pioneering rejuvenation biotechnologies to reverse the damage of aging, joined HLI's scientific advisory board as part of the LEV Foundation partnership.
• Michael LevittcoreOthers · 9 February 2026Nobel Prize-winning computational biologist (2013 Nobel Prize in Chemistry) joined the Scientific Advisory Board. Will contribute expertise in computational structural biology to advance HLI's AI-driven disease-risk prediction algorithms, including those for early-stage cancers.
• Mass General BrighamcoreTechnology or IntegrationResearch and clinical partnership with one of the world's leading academic medical centers. Collaboration announced in 2019, expanding clinical capabilities and research initiatives.
• IlluminasupportingTechnology or IntegrationTechnology partner providing sequencing infrastructure for whole genome sequencing operations.
• Siemens HealthineerssupportingTechnology or IntegrationTechnology partner providing advanced imaging equipment including MRI, CT, and other diagnostic technologies.
• Buck InstitutesupportingTechnology or IntegrationResearch partnership with the Buck Institute for Research on Aging, a leading independent research institute focused on aging research.
• CleerlysupportingTechnology or IntegrationAI-powered cardiac imaging analysis partner for cardiovascular disease detection and risk assessment.
• J. Craig Venter InstitutesupportingTechnology or IntegrationResearch partnership with the JCVI, founded by J. Craig Venter, for genomics and synthetic biology research.
• CorTechs.aisupportingTechnology or IntegrationNeuroimaging analysis technology partner for brain imaging interpretation.
• AMRA MedicalsupportingTechnology or IntegrationAMRA (Automated Multi-Organ) body composition analysis partner. AMRA BCP Scan added to 100+ Longevity Care program for advanced body composition assessment.
• DoctorsForMesupportingTechnology or IntegrationAI-powered physician matching platform developed by HLI in collaboration with Massachusetts General Hospital. Uses comprehensive health data to match patients with appropriate specialists across 40+ specialties.
• MediCardia Health Inc.supportingTechnology or IntegrationPartnership to deploy the nation's first remote monitoring platform for precision medicine, enabling continuous patient monitoring.

Scale indicators10 records

Recent moves9 records

Expansion highlights5 records

Direct peers

• Fountain Life: Fountain Life operates premium preventive-medicine and longevity centers offering whole-body MRI, advanced diagnostics, and AI-driven health assessments for affluent members — directly comparable to HLI's Executive Health and 100+ Care programs in business model and target customer.
• Prenuvo: Prenuvo provides whole-body MRI screening as a standalone consumer service, overlapping HLI's Whole Body MRI ($3,900) and diagnostic imaging layer; comparable in customer demographic (preventive-health-focused consumers) and pricing model.
• Forward Health: Forward Health operates tech-enabled preventive primary care with AI-driven health risk modeling, body scans, and genomic testing on a membership basis — comparable to HLI in its preventive, data-driven, membership-based care model for health-conscious consumers.
• 23andMe: 23andMe provides direct-to-consumer genetic testing with health and trait reports — directly comparable to HLI's $599 Genomics for All entry kit on the consumer genomics axis, though HLI differentiates on clinical-grade whole-genome coverage and depth of interpretation.

Emerging players

• Ezra: Ezra offers full-body MRI scans at lower price points ($1,350-$2,375) with AI-assisted analysis, targeting health-conscious consumers — emerging competitor in the same whole-body MRI preventive-screening category as HLI's standalone MRI offering.
• InsideTracker: InsideTracker delivers blood-based biomarker analysis with personalized longevity and performance recommendations via a consumer-facing platform — adjacent to HLI's biomarker and AI-recommendation layers, particularly for the health-conscious consumer segment below HLI's premium clinical tier.
• Elysium Health: Elysium Health develops consumer longevity products backed by clinical research and cellular-health science, intersecting with HLI's longevity focus — comparable in scientific rigor and target segment, though primarily supplement-based rather than clinical-assessment-based.

Broad incumbents

• Cleveland Clinic Executive Health: Cleveland Clinic's Executive Health program is a long-standing premium concierge preventive-medicine offering for corporate executives and high-net-worth individuals — directly comparable in target customer and comprehensive-diagnostic concept, though delivered within a broader academic hospital system.
• Mayo Clinic Executive Health Program: Mayo Clinic's Executive Health program is a flagship premium preventive-medicine offering for executives that bundles advanced diagnostics, imaging, and specialist consultations in a single-day visit — a broad incumbent counterpart to HLI's Executive Health program in concept and customer segment.
• Tempus AI: Tempus applies AI to multi-modal clinical and molecular data (genomics, imaging, clinical records) for precision medicine — comparable in technology stack and data-platform ambition to HLI's Longevity AI/Insilico foundation-model work, though broader in clinical focus.

Market position

Strengths5 records

Weaknesses4 records

Competitive moat5 records

Key risks5 records

Key highlights6 records

Customer concentration

• YouTubeyoutube.com/@HumanLongevity
• LinkedInlinkedin.com/company/human-longevity-inc-
• Instagraminstagram.com/humanlongevityinc
• Xx.com/humanlongevity
• Facebookfacebook.com/humanlongevity

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles11 records

Subsidiaries2 records

Funding overview

Funding rounds4 records

Investors13 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A2 records

Investments5 records

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Human Longevity