Zane Venture Fund
Zane Venture Fund is an Atlanta-based early-stage venture capital firm backing health innovation founders with lived experience, operating Fund I and Fund II, the Zane Access 501(c)(3) accelerator, and the annual Healthy Human Economy Innovation Exchange summit.
- Company typePrivate
- Founded2020
- HeadquartersAtlanta, United States
- Headcount1–10
- GTM typeB2B
- OfferingServices
What Zane Venture Fund does
Zane Venture Fund is an Atlanta-based early-stage venture capital firm that invests in health innovation startups, with a stated preference for founders who have lived experience with the health conditions their products address. The firm operates a "Healthy Human Economy" investment thesis spanning health-tech, wellness, and consumer health categories. Zane runs multiple product lines: Fund I (a venture vehicle that has deployed into 9 portfolio companies and attracted $40M in follow-on capital at a 24x follow-on multiplier), the actively raising Fund II, the Zane Access 501(c)(3) accelerator (which has supported 100+ founders who subsequently raised $21M post-graduation), and the annual Healthy Human Economy Innovation Exchange summit. The firm also operates a Zane Network that connects founders with strategic and corporate capital partners including Shopify, Google Cloud, Bank of America, Thompson Hine, Serena Ventures, and Southern Company.
Zane's revenue model is that of a traditional venture capital firm: earning management fees (typically ~2% of committed capital) on Fund I and Fund II, with the potential for carried interest on profitable exits. Deal flow is sourced through the Zane Access accelerator pipeline, university partnerships with 8+ institutions (Brown, Yale, Georgia Tech, Harvard, Emory, MIT), and strategic LP relationships including American Heart Association Ventures and Conscious Venture Partners. The fund's first vehicle made 9 investments that collectively grew at 3x average annual pace, with strategic follow-on capital validating the thesis.
The firm's core differentiator is its lived-experience founder thesis combined with operational specialization in health. The partnership includes Founder/Managing Partner Shila Nieves Burney (20 years of health industry experience) and Venture Partner Sig Mosley (described as the "Godfather of Angel Investing in the Southeast" with a $5.7B exit track record), supported by Strategic Advisor Rachel Wilson. Zane competes primarily as an emerging manager in a fragmented early-stage health-tech market, leveraging its Atlanta base (reportedly 40% less venture competition than coastal markets) and nonprofit accelerator structure as structural advantages.
Zane Venture Fund firmographics
Firmographics- Name
- Zane Venture Fund
- Legal name
- Zane VC
- Website
- https://zane.vc
- Company type
- Private
- Founded year
- 2020
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Short description
- Zane Venture Fund is an Atlanta-based early-stage venture capital firm backing health innovation founders with lived experience, operating Fund I and Fund II, the Zane Access 501(c)(3) accelerator, and the annual Healthy Human Economy Innovation Exchange summit.
- Ownership category
- akta.pro rank
Zane Venture Fund industry classification
Industry- Product category
- Healthcare Venture Capital
- NAICS
- Other Investment Pools and Funds (5259)
- SIC
- Investment Advice (6282)
- akta.pro primary industry
- Early-Stage Venture Capital (Series A/B) (FSANAAAB)
- akta.pro secondary industry
- Sector-Focused Venture Capital (Vertical Specialists) (FSANAAAD)
Keywords
Where Zane Venture Fund is headquartered
LocationHeadquarters
- HQ city
- Atlanta
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Zane Venture Fund business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Operations, Marketing or Sales, Technology or R&D, Others
Revenue model
- Venture Capital Returns: Returns generated through equity investments in portfolio companies. Fund I demonstrated 24x follow-on multiplier and $40M in follow-on funding across 9 portfolio companies.
Go-to-market motion2 records
Distribution channels3 records
Marketing channels5 records
Zane Venture Fund product offering
Product offeringCore offering
Zane Venture Fund is an early-stage venture capital firm that invests in pre-seed to $500K ARR stage founders building B2B health innovation platforms for payers, employers, and health systems. The firm operates Fund I and is currently raising Fund II, channels deal flow through the Zane Access 501(c)(3) accelerator, and convenes the annual Healthy Human Economy Innovation Exchange summit to connect founders, investors, and health system leaders.
Product overview
Zane Venture Fund is an early-stage venture capital firm that operates as both an investment fund (Fund I and Fund II) and a platform with supporting programs. The core investment strategy focuses on backing founders with lived experience building platforms that deliver health outcomes to employers, payers, and health systems. The firm's product ecosystem includes Zane Access, a 501(c)(3) accelerator program that provides pre-seed founders with capital readiness training over eight weeks, and the annual Healthy Human Economy Innovation Exchange summit. Fund I has achieved a 24x follow-on multiplier across 9 portfolio companies, with Fund II narrowing focus specifically to health outcomes investing.
Differentiator
Problem solved
Functional benefit
Brands
- Healthy Human Economy®: A registered trademark and investment thesis framework focused on the intersection of proactive health and economic opportunity.
- Zane Access®
Products and services
- Fund II Early-stage venture capital fund focused on health outcomes investing, backing founders with clinical backgrounds and lived experience building B2B platforms that deliver health outcomes to employers, payers, and health systems. Targeted at accredited investors and institutional LPs.
- Zane Access A 501(c)(3) accelerator platform for pre-seed founders in healthcare that provides education, mentoring, and capital readiness training over an eight-week program. Founders emerge with clarity on their business, connections to capital, and momentum to execute.
- Healthy Human Economy Innovation Exchange The Southeast's premier health innovation summit held during Atlanta Tech Week, bringing together investors, founders, health system leaders, and payers to move the future of health from vision to value.
- Fund I First venture capital fund of Zane Venture Fund, investing in early-stage founders building B2B health innovation platforms. Achieved a 24x follow-on multiplier across 9 portfolio companies with $40M in follow-on funding and 3x average annual revenue growth.
Quantifiable outcome
- 24x follow-on multiplier for every $1 invested
- +3 more outcomes
Companies that use Zane Venture Fund
Customer profileNamed customers9 records
Segments1 record
Ideal customer profiles3 records
Zane Venture Fund technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Zane Venture Fund partnerships and signals
Strategic signalPartnerships
Nine partnerships are on record, tiered minor.
- Brown UniversityminorPartner backing Zane Access accelerator program supporting founders at the intersection of care delivery and entrepreneurship.
- Yale UniversityminorPartner backing Zane Access accelerator program.
- Georgia TechminorPartner backing Zane Access accelerator program.
- Harvard UniversityminorPartner backing Zane Access accelerator program.
- Emory UniversityminorPartner backing Zane Access accelerator program.
- MITminorPartner backing Zane Access accelerator program.
- ShopifyminorPartner backing Zane Access accelerator program.
- Thompson Hine LLPminorLaw firm partner providing legal office hours at summit events for founders on procurement and compliance questions.
- TECHPLUGminorKornelius Bankston from TECHPLUG moderating the From Clinic to Contract panel at the Healthy Human Economy Innovation Exchange.
Scale indicators10 records
Recent moves6 records
Expansion highlights6 records
Zane Venture Fund competitors and assessment
Company assessmentDirect peers
- Define Ventures: Early-stage venture capital firm focused on digital health, investing at seed and Series A. Comparable to Zane VC in stage focus, health vertical specialization, and B2B platform thesis targeting payers, providers, and employers.
- Flare Capital Partners: Early-stage healthcare technology venture capital firm investing in seed and Series A rounds. Directly comparable in stage, health-tech focus, and B2B platform orientation toward payers, providers, and employers.
- Town Hall Ventures: Healthcare-focused venture capital firm investing in companies serving vulnerable populations through value-based care models. Comparable in healthcare specialization, mission-driven investing lens, and focus on founders addressing systemic health gaps.
- Catalyst Health Ventures: Early-stage healthcare technology and services venture capital firm. Closely comparable in seed/Series A stage focus, health-tech vertical, and B2B orientation toward payers, providers, and employers.
- Oak HC/FT: Venture capital firm focused exclusively on healthcare, investing across stages in healthcare services and fintech. Comparable in healthcare-only thesis, B2B platform focus, and payer/employer/health system buyer orientation.
- Conscious Venture Partners: Early-stage venture firm investing in underestimated founders building mission-driven companies. Directly comparable to Zane VC in founder thesis, follow-on investor role in Zane portfolio companies, and mission alignment on health equity.
Broad incumbents
- Andreessen Horowitz (a16z Bio + Health): Large multi-stage venture firm with dedicated Bio/Health fund investing across healthcare and life sciences. Overlaps with Zane VC on health-tech investing and founder support, but operates at significantly larger fund sizes and broader stage range.
- Khosla Ventures: Large early-stage venture firm with significant healthcare and consumer health investing. Comparable in seed/Series A stage focus and willingness to back unconventional founders, but with much broader sector mandate and larger fund sizes.
Regional players
- Collab Capital: Atlanta-based early-stage venture fund focused on underestimated founders. Directly comparable to Zane VC in Atlanta base, underrepresented-founder thesis, and ecosystem overlap (Collab Capital speaks at Zane's annual summit).
- Mosley Ventures: Atlanta-based early-stage venture firm led by Sig Mosley (also a Venture Partner at Zane VC). Comparable in Atlanta base, early-stage stage focus, and deep overlap in leadership, networks, and portfolio adjacency.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks6 records
Key highlights6 records
Customer concentration
Zane Venture Fund social profiles
Digital presenceZane Venture Fund financial estimates
Financial estimateRevenue estimate
Valuation estimate
Zane Venture Fund leadership team
Management profileNumber of profiles
Profiles3 records
Zane Venture Fund funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Zane Venture Fund M&A and investment
M&A and investmentM&A
Investments20 records
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Zane Venture Fund
What does Zane Venture Fund do?
Zane Venture Fund is an early-stage venture capital firm that invests in pre-seed to $500K ARR stage founders building B2B health innovation platforms for payers, employers, and health systems. The firm operates Fund I and is currently raising Fund II, channels deal flow through the Zane Access 501(c)(3) accelerator, and convenes the annual Healthy Human Economy Innovation Exchange summit to connect founders, investors, and health system leaders.
Is Zane Venture Fund a public or private company?
Zane Venture Fund is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was Zane Venture Fund founded?
Zane Venture Fund was founded in 2020. It employs 1 to 10 people.
Where is Zane Venture Fund based?
Zane Venture Fund is headquartered in Atlanta, United States, in the North America region.
How does Zane Venture Fund make money?
One revenue line is on record: venture Capital Returns.
Who are Zane Venture Fund's main competitors?
Direct peers on record are Define Ventures, Flare Capital Partners, Town Hall Ventures, Catalyst Health Ventures, Oak HC/FT and Conscious Venture Partners. Broad incumbents are Andreessen Horowitz (a16z Bio + Health) and Khosla Ventures. Regional players are Collab Capital and Mosley Ventures.
Does Zane Venture Fund have an API?
No public API is recorded for Zane Venture Fund.
What industry is Zane Venture Fund in?
Zane Venture Fund's product category is Healthcare Venture Capital. Its primary akta.pro industry code is FSANAAAB, Early-Stage Venture Capital (Series A/B), with a secondary code of FSANAAAD, Sector-Focused Venture Capital (Vertical Specialists). Its NAICS code is 5259 and its SIC code is 6282.