What Briya does

Briya is an Israeli-American healthtech AI company founded in 2021 and headquartered in New York, with offices in Nashville and Tel Aviv. The company operates a blockchain-secured healthcare data exchange and research platform called Briya AIRE (AI Research Environment), which aggregates de-identified clinical data from hospitals, health systems, and research institutions globally. As of recent disclosures, Briya reports a network spanning 120 million+ patient journeys across multiple countries, with 22 analytics modules and 9 purpose-built AI agents built on proprietary medically-trained large language models. The platform supports FHIR and OMOP interoperability standards, offers on-premise AI deployment, and integrates with Epic's Connection Hub and InterSystems' health data fabric.

Briya serves a heterogeneous customer base spanning life sciences, biopharmaceutical companies, hospitals, and academic research institutions. Named enterprise customers include Merck (MSD), Biogen, Charité (Berlin), Casa Sollievo della Sofferenza (Italy), Tanner Health System (US), and Shaare Zedek Medical Center (Israel). The company operates a hybrid go-to-market combining direct enterprise sales for large biopharma and health system contracts with a freemium self-serve tier, a $25/month premium subscription, custom enterprise contracts, and distribution through AWS Marketplace. Briya holds ISO 27001 certification (June 2024) and HIPAA Expert Determination (May 2025), supporting regulated data workloads in US, EU, and Israeli markets. To date, Briya has raised approximately $17M across a $5.5M seed round (April 2022, led by Amiti Ventures) and an $11.5M Series A (September 2023, led by Team8), with participation from Insight Partners, Innocare Health Investments, and the George Kaiser Family Foundation.

Name

Briya

Legal name

Bria Interoperability Ltd.

Website

https://briya.com

Company type

Private

Founded year

2022

Operating status

Operating

Headcount range

51–100 employees

Short description

Briya is a healthcare AI company that aggregates de-identified clinical data from hospitals and research institutions via its blockchain-secured AIRE platform, serving biopharma, hospitals, and academic researchers across multiple countries.

Ownership category

akta.pro rank

Product category

Clinical Research Software

NAICS

Software Publishers (5132), Software Publishers (513210)

akta.pro primary industry

Clinical Trial Informatics (EDC/CTMS/eCOA/eTMF) (HLAGAJAM)

akta.pro secondary industries

Scientific Data Management & Data Platforms (SDMS/Data Lakehouse for R&D) (HLAGAJAC), De-identification, Tokenization & Privacy-Preserving Data Platforms (HLACAIAK)

Keywords

• Healthcare data exchange
• Real-world data platform
• Clinical research AI
• Medical research analytics
• De-identified patient data

Headquarters

HQ city

New York

HQ country

United States

HQ region

North America

Offices3 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Infrastructure, Marketing or Sales, Operations

Revenue model

1. AIRE Freemium / Subscription: Free public access to AIRE conversational AI platform for clinical, epidemiological and real-world evidence research; premium features available for $25 per month subscription, enabling monetization of advanced features while capturing a wide user base through freemium funnel.
2. AIRE Premium Subscription: Recurring $25/month premium tier of AIRE with advanced capabilities beyond free public access.
3. Custom Dynamic Datasets (Data Monetization): Customized, condition-specific real-world data mastersets sold to life sciences and biopharma customers (e.g., Maternal Health, Duchenne, Alzheimer's, CKD, CLL, Ovarian Cancer, Breast Cancer, German RWD); researchers request specific variables and demographics and Briya provides a custom proposal.
4. Enterprise Platform Licensing (AWS Marketplace): Briya AIRE available for purchase via AWS Marketplace, enabling streamlined procurement and onboarding for healthcare and life science organizations with use cases across RWE generation, clinical development, HEOR, epidemiology, and health innovation.
5. Strategic Collaboration & Professional Services: Strategic collaborations with biopharma (e.g., MSD, Biogen) and hospitals (e.g., Casa Sollievo della Sofferenza, Charité, Tanner Health System) for joint RWE data analysis, real-world evidence generation, and integrated research projects.

Pricing tiers

Go-to-market motion5 records

Distribution channels5 records

Marketing channels9 records

Core offering

Briya operates a blockchain-secured healthcare data exchange platform that allows hospitals and life sciences organizations to share de-identified health data without moving or duplicating it. On top of this, it offers Briya AIRE, a clinical-grade AI Research Environment with 9 purpose-built AI agents and 22 analytics modules that enables researchers to query, analyze, and generate datasets from longitudinal real-world patient data using medically-trained LLMs and NLP. The company also sells condition-specific Dynamic Datasets (Maternal Health, Alzheimer's, Breast Cancer, etc.) to life sciences customers.

Product overview

Briya offers a unified platform-plus-modules architecture: the core offering is a blockchain-secured healthcare data exchange platform that connects hospitals and life-sciences organizations, on top of which sits Briya AIRE (the AI Research Environment) as the primary product. AIRE is extended by Dynamic Datasets — pre-built, disease-specific ready-to-use datasets (Maternal Health, Duchenne, Alzheimer's, CKD, CLL, Ovarian Cancer, Breast Cancer, etc.) — and by AIRE Agents, purpose-built autonomous agents that automate multi-step clinical research workflows using LLMs, RAG, and predictive analytics over de-identified real-world patient data.

Differentiator

Problem solved

Functional benefit

Brands

• Briya AIRE (AIRE™): The AI Research Environment — a clinical-grade, browser-based AI research platform with purpose-built agents for harmonization, population, design, methodology, descriptives, and analytics; available on AWS Marketplace and as a free browser-based offering.

Products and services

• Briya AIRE (AI Research Environment) A clinical-grade, browser-based AI research environment with 9 purpose-built AI agents (Literature, Hypothesis, Population, Design, Methodology, Harmonization, Descriptives, Summary, Analytics) and 22 analytics modules that enables life-sciences researchers, hospitals, and academic users to run end-to-end clinical research workflows on de-identified real-world data without coding.
• Dynamic Datasets Pre-built, disease-specific, revisitable and updatable real-world data mastersets (Maternal Health, Duchenne Muscular Dystrophy, Alzheimer's, Chronic Kidney Disease, Chronic Lymphocytic Leukemia, Ovarian Cancer, Breast Cancer, German RWD) sold to life sciences and biopharma customers for condition-specific research.
• Blockchain-Secured Healthcare Data Exchange Platform End-to-end blockchain-secured data exchange platform that allows hospitals and life sciences organizations to share de-identified health data without moving or duplicating it; data stays at the source with no warehouses, supporting FHIR/OMOP-compliant data models and three-layered de-identification.

Quantifiable outcome

• 10x acceleration in innovation
• +5 more outcomes

Named customers6 records

Segments5 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration3 records

AI capability9 records

Feature8 records

Partnerships

18 partnerships are on record, tiered flagship, core and minor.

• InterSystemsflagshipStrategic or Co-development Partner · 19 May 2026Strategic partnership announced May 19, 2026 to integrate Briya's AI research platform with InterSystems' data infrastructure (powering over 1 billion health records globally). Enables healthcare and life sciences researchers to query longitudinal patient datasets using natural language while maintaining GDPR and HIPAA compliance. Demonstrated at InterSystems READY 2026 global summit.
• Epic (Connection Hub)flagshipTechnology or Integration · 2 December 2025Briya listed on Epic Connection Hub (December 2, 2025), enabling integration with Epic EHR systems. Tanner Health System became the first live implementation using Briya within its Epic EHR to improve data sharing and healthcare research.
• AWS (Amazon Web Services) MarketplaceflagshipChannel Partner/ Reseller/ Distributor · 23 October 2025Briya AIRE available for purchase via AWS Marketplace (October 23, 2025), enabling streamlined procurement and onboarding for healthcare and life science organizations. Customers can initiate AIRE procurement through their AWS portal, simplifying security and compliance reviews.
• Biogen HLTH Rare Disease AcceleratorcoreStrategic or Co-development Partner · 10 June 2025Selected as one of five contributors from hundreds of applications to the Biogen HLTH Rare Disease Accelerator (June 10, 2025). Supports Biogen's rare disease portfolio (Friedreich's Ataxia, SMA, ALS) with planned expansion into liver health. Briya's AI/NLP and complete longitudinal patient journey capabilities are central to this partnership.
• Casa Sollievo della SofferenzaflagshipStrategic or Co-development Partner · 27 May 2025Italian hospital and research institution partnership announced May 27, 2025 to make European healthcare data more accessible to researchers worldwide. Casa Sollievo della Sofferenza treats over 200,000 patients annually and was ranked #1 hospital in Southern Italy by Newsweek 2024. Dr. Gino Gumirato (CEO) is engaged in enabling access to high-quality Italian RWD. Francesco Giuliani (Head of Research and Innovation) integrates Briya AI Copilot.
• Decode HealthminorStrategic or Co-development Partner · 28 March 2023Tapped by Decode as new precision medicine data-sharing partner (March 28, 2023).
• SUDEP Data Alliance (with Neureka®)coreStrategic or Co-development Partner · 2 December 2022Cofounded by Neureka® and Briya to develop life-saving interventions for SUDEP (Sudden Unexpected Death in Epilepsy). Cove Neurosciences joined the alliance in June 2023.
• Intel IgniteminorStrategic or Co-development Partner · 10 November 2022Joined Intel Ignite's 7th cohort in Tel Aviv (November 10, 2022), an exclusive accelerator program for deep tech startups. Selected from over 200 applicants.
• UC Berkeley Health EngineminorStrategic or Co-development Partner · 21 September 2022Joined UC Berkeley's prestigious Health Engine 3rd cohort (September 21, 2022), a health-tech accelerator program.
• CharitéflagshipStrategic or Co-development PartnerRenowned German hospital serving as trusted healthcare partner in Briya's German RWD network. Part of a partnership enabling access to 11M+ de-identified German patient records, 118M patient-doctor interactions, 51M diagnosis-tagged visits, 68M service records with full GDPR compliance.
• MSD (Merck)flagshipStrategic or Co-development PartnerStrategic collaboration announced October 10, 2024 for innovative RWE data analysis projects. Udi Cohen, MSD IL Commercial Operations Director, said: 'Briya's data curation techniques shed new light on analyzing clinical data to generate insights.'
• Cove NeurosciencesminorStrategic or Co-development PartnerJoined the SUDEP Data Alliance (cofounded by Neureka® and Briya) on June 29, 2023 to develop life-saving interventions for SUDEP.
• Galilee Medical CenterminorStrategic or Co-development PartnerPartnered with Briya (Dr. Tzvi Sheleg) on ISPOR Europe 2024 study on aspirin use during pregnancy demonstrating the value of NLP for uncovering critical data in clinical research.
• Shaare Zedek Medical CentercoreStrategic or Co-development PartnerIsraeli medical center using Briya's advanced NLP capabilities to identify patients with 'at-risk MASH' (fibrosis stage ≥ F2) directly from unstructured clinical data, enabling timely referral to hepatology and access to emerging treatments. Gadi Lalazar, M.D., Director of Hepatology, is referenced as a customer advocate.
• Prof. Siegal SadetzkiflagshipOthersRenowned public health expert, epidemiologist, and former Chief Epidemiology Officer at Briya; joined in June 2024 from Israeli MoH where she led during COVID-19. She shapes Briya's epidemiologically-aware AI research vision and is a frequent contributor.
• Prof. Jonathan Samet, MD, MSflagshipOthersAppointed Chief Epidemiologist of Briya (May 27, 2026) to lead integration of epidemiological methodology into the AIRE research engine. Brings 40+ years of experience from Johns Hopkins and the University of Colorado; member of the National Academy of Medicine.
• Fabio Lievano, M.D.minorOthersScientific Advisor to Briya; VP Safety Science at Abbvie. Provides scientific and pharmaceutical industry guidance.
• Moshe Bar Siman TovminorOthersFormer Board Advisor and Former Director General of the Israeli Ministry of Health. Provides policy-level healthcare expertise.

Scale indicators13 records

Recent moves12 records

Expansion highlights7 records

Direct peers

• TriNetX: Global clinical research network enabling protocol design, feasibility, and real-world evidence across 200+ healthcare organizations; competes head-on with Briya AIRE for pharma-sponsored RWE studies.
• Flatiron Health: Roche-owned oncology real-world data and EHR-linked analytics platform; the closest direct competitor in the 'AI-enabled harmonization of clinical real-world data for life sciences' category that Briya targets.
• Datavant: Healthcare data connectivity and de-identification layer for linking real-world data across providers; competes with Briya's blockchain-secured, on-premise data exchange architecture for hospital-to-life-sciences data flows.
• Aetion: Real-world evidence analytics platform used by top biopharma and regulators (including FDA collaborations) for RWE generation; a direct peer for Briya's AI-driven RWE and HEOR use cases.

Broad incumbents

• IQVIA: Largest clinical research and real-world evidence organization globally; overlaps with Briya on biopharma RWE, HEOR, and study feasibility but as part of a much broader CRO and data services portfolio.
• Tempus: Large AI-powered precision medicine platform combining multi-modal clinical and molecular data for biopharma and providers; broader scope than Briya but overlapping on AI-driven clinical research and condition-specific datasets.
• Health Catalyst: Healthcare analytics and data platform for health systems, serving similar enterprise hospital buyers as Briya but with a broader focus on operational and clinical analytics rather than life-sciences RWE.
• Palantir Foundry: Enterprise data platform with deep adoption among large healthcare systems, life sciences, and government health agencies; competes with Briya for hospital data harmonization and analytics workloads at the high end of the market.

Emerging players

• Atropos Health: Real-world evidence generation service using de-identified patient data to answer clinician and life-sciences questions; an emerging peer with strong overlap on the 'chat-with-data' research workflow that Briya AIRE delivers.
• Mendel: AI platform that structures and reasons over unstructured clinical text for life-sciences research; a focused emerging peer to Briya's medically-trained LLM and NLP capabilities.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat7 records

Key risks6 records

Key highlights7 records

Customer concentration

• Facebookfacebook.com/briya.health
• LinkedInlinkedin.com/company/briyahealth
• Xx.com/BriyaHealth

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles10 records

Funding overview

Funding rounds4 records

Investors6 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Briya