Zap Surgical Systems

What Zap Surgical Systems does

ZAP Surgical Systems, Inc. designs, manufactures, and sells the ZAP-X Gyroscopic Radiosurgery platform, a self-shielded, vault-free, cobalt-free dedicated cranial stereotactic radiosurgery (SRS) system. Founded in 2014 by Dr. John R. Adler, Jr., the inventor of the CyberKnife and founder of Accuray (NASDAQ: ARAY), the company is headquartered in San Carlos, California, and operates regional sales entities in Japan, India, and China, with 51-100 employees as of the most recent disclosure.

The ZAP-X system is built around a modern 3MV linear accelerator and a unique dual independent gyroscopic gantry that delivers non-coplanar radiation from thousands of unique beam angles, with a 45 cm source-to-axis distance that reduces beam penumbra by up to 50% relative to whole-body 100 cm systems and a tungsten-shielded collimator with leakage below 0.002%. The platform is complemented by the ZAP-Axon Radiosurgery Planning System (FDA 510(k) and EU CE cleared in November 2025) and the optional PinZ Patient Immobilizer (U.S. FDA cleared). ZAP-X has received U.S. FDA 510(k) clearance in 2017, Japan Shonin in 2020, EU CE in 2021, and Chinese NMPA innovative product registration in 2023.

ZAP operates a direct enterprise sales motion targeting neurosurgeons, radiation oncologists, hospital administrators, and medical physicists, with regional sales leadership across the Americas, EMEA/Central Asia, Japan/APAC, China, and India. Revenue derives primarily from capital equipment sales of ZAP-X systems (quote-based, multi-year contracts) supplemented by service, maintenance, and clinical support contracts. The customer base spans academic medical centers (Gustave Roussy, Peking University International Hospital, MedStar Georgetown), specialty radiosurgery clinics (European Radiosurgery Center Munich, Swiss Neuro Radiosurgery Center), community hospitals (St. Bonifatius Lingen, Haaglanden Medical Center), and large hospital groups (Apollo Hospitals, Larkin/Miami Neuroscience Center), with 30+ global installations and more than 5,000 patients treated as of August 2025.

Name

Zap Surgical Systems

Legal name

ZAP Surgical Systems, Inc.

Website

https://zapsurgical.com

Company type

Private

Founded year

2014

Operating status

Operating

Headcount range

51–100 employees

Short description

ZAP Surgical Systems designs and manufactures the ZAP-X Gyroscopic Radiosurgery platform, a self-shielded, vault-free, cobalt-free dedicated cranial SRS system sold to hospitals and outpatient centers globally.

Ownership category

akta.pro rank

Product category

Radiosurgery Equipment

NAICS

Irradiation Apparatus Manufacturing (334517), Electromedical and Electrotherapeutic Apparatus Manufacturing (334510)

SIC

X-Ray Apparatus & Tubes & Related Irradiation Apparatus (3844), Electromedical & Electrotherapeutic Apparatus (3845), Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Interventional Radiology & Image-Guided Therapy Systems (HLAHABAG)

akta.pro secondary industry

Radiation Therapy Planning & Simulation Imaging (CT Sim/MR Sim) (HLAHABAH)

Keywords

• Cranial radiosurgery systems
• Stereotactic radiosurgery equipment
• Medical linear accelerators
• Radiotherapy planning software
• Neurosurgery medical devices

Headquarters

HQ city

San Carlos

HQ country

United States

HQ region

North America

Offices3 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Supply Chain, Marketing or Sales, Personnel, Operations, Infrastructure

Revenue model

1. Capital equipment sales (ZAP-X systems): Sale of the ZAP-X Gyroscopic Radiosurgery platform as a high-capital medical device to hospitals and outpatient centers; supplemented by multi-system orders and reference-site agreements (e.g., Apollo Hospitals multi-system deal). Multi-year capital purchase cycle.
2. Service, maintenance, and clinical support contracts: Ongoing service, training, and support for installed ZAP-X sites, including the publication program, planning studies, and clinical webinars referenced across global installations.
3. License, trademark, and brand-related IP royalties: Implied IP / trademark licensing around the ZAP, ZAP-X, Z symbol, and GYROSCOPIC RADIOSURGERY brands (registered trademarks of ZAP Surgical Systems, Inc.).

Pricing tiers

Go-to-market motion3 records

Distribution channels7 records

Marketing channels9 records

Core offering

ZAP Surgical Systems designs, manufactures, and sells the ZAP-X Gyroscopic Radiosurgery platform, a self-shielded, vault-free, cobalt-free dedicated cranial stereotactic radiosurgery (SRS) system that uses a modern linear accelerator with a dual independent gyroscopic gantry to deliver non-coplanar radiation from thousands of unique beam angles. The company complements the platform with the ZAP-Axon Radiosurgery Planning System (companion treatment planning software) and the PinZ Patient Immobilizer accessory, and provides related installation, training, and clinical support services to hospitals and outpatient centers globally.

Product overview

ZAP Surgical Systems offers a focused medical-device platform built around a single core product, the ZAP-X Gyroscopic Radiosurgery platform, complemented by the ZAP-Axon Radiosurgery Planning System (the companion treatment-planning software module cleared in November 2025) and the PinZ Patient Immobilizer accessory for additional patient stabilization. The ZAP-X is a self-shielded, vault-free, cobalt-free dedicated cranial radiosurgery robot using a linear accelerator and dual independent gyroscopic gantries; the ZAP-Axon Planning System plugs in as the treatment-planning module for that platform, and the PinZ immobilizer is an optional add-on. Together, these products form a tightly integrated cranial stereotactic radiosurgery (SRS) solution rather than a broad multi-product platform.

Differentiator

Problem solved

Functional benefit

Brands

• ZAP-X: Gyroscopic Radiosurgery platform - a self-shielded, vault-free, cobalt-free dedicated cranial radiosurgery system using a modern linear accelerator.
• ZAP-Axon
• PinZ
• Gyroscopic Radiosurgery

Products and services

• ZAP-X Gyroscopic Radiosurgery Platform Self-shielded, vault-free, cobalt-free robotic radiosurgery platform dedicated exclusively to cranial stereotactic radiosurgery. Uses a modern linear accelerator with a unique dual independent gyroscopic gantry design to deliver non-coplanar radiation from thousands of beam angles, designed to spare healthy brain tissue and protect neurocognitive function. Sold to hospitals, academic medical centers, and outpatient centers.
• ZAP-Axon Radiosurgery Planning System Companion treatment planning software for the ZAP-X platform, designed for cranial stereotactic radiosurgery. Reports approximately 20% reduction in overall planning time with optimal cases planned in as little as five minutes. Sold as a standalone software module integrating with the ZAP-X platform.
• PinZ Patient Immobilizer Optional immobilization accessory for the ZAP-X platform designed for patients requiring additional stabilization during treatment (e.g., patients with Parkinson's disease or tremors). U.S. FDA cleared; clearance pending in other regions.

Quantifiable outcome

• Reduces CO2 emissions to about one-quarter of bunker-based systems by eliminating the concrete vault
• +6 more outcomes

Named customers18 records

Segments5 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature8 records

Partnerships

13 partnerships are on record, tiered core and flagship.

• Kaohsiung Show Chwan Memorial Hospital (KSCH) / Show Chwan Healthcare SystemcoreChannel Partner/ Reseller/ Distributor · 1 May 2026Grand opening of ZAP-X installation at KSCH in Taiwan in May 2026, anchoring the region's next-generation neuro-oncology program with planned patient treatments beginning June 2026.
• Haaglanden Medical Center (Netherlands)flagshipChannel Partner/ Reseller/ Distributor · 1 January 2026First hospital in the Netherlands to install ZAP-X (January 28, 2026).
• Gustave RoussyflagshipChannel Partner/ Reseller/ Distributor · 1 December 2025Gustave Roussy will install the ZAP-X Gyroscopic Radiosurgery platform, completing by the end of 2024 with treatments beginning in early 2025; described as installing the world's most advanced non-invasive brain surgery platform.
• Alfried Krupp Hospital (Germany)coreChannel Partner/ Reseller/ Distributor · 1 November 2025Fourth ZAP-X installation in Germany (November 5, 2025), boosting patient-centered brain tumor care.
• Peking University International HospitalflagshipStrategic or Co-development Partner · 1 October 2025Establishing a next-generation ZAP-X radiosurgery center in China (October 28, 2025), expanding access in the Chinese market following 2023 NMPA innovative product registration.
• AIG HospitalscoreChannel Partner/ Reseller/ Distributor · 1 July 2025Bringing ZAP-X Gyroscopic Radiosurgery to South India (July 16, 2025).
• Ibn Sina Medical Center (Morocco)flagshipChannel Partner/ Reseller/ Distributor · 1 July 2025Brought the ZAP-X platform to Africa as the first African installation (July 1, 2025).
• Gray Medical Institute (Mexico)coreChannel Partner/ Reseller/ Distributor · 1 June 2025First ZAP-X program in Mexico and Latin America, with first patient treatments announced June 19, 2025.
• Dongguk University Ilsan HospitalcoreChannel Partner/ Reseller/ Distributor · 1 July 2024Completed first ZAP-X brain tumor treatments on July 2, 2024, expanding cranial SRS access in South Korea.
• IMS Shin-Matsudo Central HospitalcoreChannel Partner/ Reseller/ Distributor · 1 July 2024Completed first ZAP-X treatment on July 31, 2024, in Japan.
• Apollo Hospitals Enterprise Ltd.flagshipStrategic or Co-development Partner · 1 March 2024Strategic partnership and multi-system ZAP-X order announced in early 2024. First patient treatment completed at Apollo Hospital New Delhi in March 2024, with the site designated as the regional reference site for customer training and facility visits.
• Barrow Brain & SpineflagshipStrategic or Co-development PartnerBarrow Brain & Spine's clinical team is featured in ZAP's "First in Man" documentary, having treated the first patient with ZAP-X. The relationship is foundational for the platform's clinical credibility.
• Stanford University (Adler affiliation)coreStrategic or Co-development PartnerFounder/CEO Dr. John R. Adler, Jr. is Emeritus Dorothy & TK Chan Professor of Neurosurgery and Radiation Oncology at Stanford University since 1987. Stanford connections support clinical-research collaboration.

Scale indicators12 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Accuray: Accuray (NASDAQ: ARAY) sells the CyberKnife robotic radiosurgery system, ZAP-X's closest direct competitor in image-guided radiosurgery. The relationship is uniquely tight because ZAP Surgical's founder/CEO Dr. John R. Adler, Jr. is also Accuray's founder. Both companies sell robotic SRS platforms to neurosurgery and radiation oncology customers globally.
• Elekta: Elekta is the global incumbent in cranial SRS through its Gamma Knife system (Co-60-based) and a major whole-body LINAC vendor (Versa HD). As the dominant legacy cranial SRS supplier with a massive installed base, Elekta is the most direct peer competing for the same neurosurgery/hospital customer budget.
• RaySearch Laboratories: RaySearch develops RayStation and RayCare treatment planning and oncology information systems used across radiation therapy. ZAP-Axon competes in the same treatment planning category, making RaySearch the closest software-side peer — and a potential partner or competitor depending on ZAP's openness to multi-vendor planning environments.

Broad incumbents

• Varian (Siemens Healthineers): Varian (now part of Siemens Healthineers) is the largest radiation oncology platform vendor globally, selling TrueBeam, Edge, and Halcyon LINAC systems that compete against ZAP-X in hospitals capable of performing radiosurgery on whole-body platforms. Varian's scale, installed base, and bundled software (Eclipse) make it the dominant alternative for hospital capex committees.
• IBA (Ion Beam Applications): IBA is a global leader in proton therapy (ProteusONE, ProteusPLUS) and a broader radiopharmaceutical/dosimetry vendor. While primarily a particle therapy player, IBA is an incumbent alternative modality competing for hospital radiation oncology capex and could win against ZAP-X in academic centers evaluating proton over photon SRS.
• Canon Medical Systems (Radiation Oncology): Canon Medical offers the Veloce and Aquilion RT systems integrated into radiation oncology workflows, partnering with multiple LINAC vendors. As a broader radiation therapy ecosystem incumbent, Canon competes at the hospital procurement level for integrated imaging-and-treatment solutions.

Emerging players

• Brainlab: Brainlab offers image-guided surgery and radiosurgery planning software (Elements, ExacTrac) that competes with ZAP-Axon at the planning layer and integrates with multiple LINAC vendors. Brainlab overlaps with ZAP in neurosurgical and SRS treatment-planning workflows but does not sell a dedicated cranial SRS delivery platform.
• ViewRay: ViewRay pioneered MR-guided radiation therapy (MRIdian) for adaptive radiotherapy in cranial and extracranial indications. While not a direct cranial SRS competitor, ViewRay's MR-guided approach represents an alternative technological trajectory that could pull hospital capex and physician mindshare away from dedicated SRS platforms like ZAP-X.
• Mevion Medical Systems: Mevion sells compact proton therapy systems (MEVION S250i with HYPERSCAN pencil beam scanning) targeted at single-room, lower-cost proton deployments. As proton therapy becomes more competitive in cranial indications, Mevion represents an adjacent modality competing for the same hospital capital and cranial patient population.
• RefleXion Medical: RefleXion is developing biology-guided radiotherapy (BgRT) that uses PET signals to track tumors in real time, primarily targeting metastatic disease. While extracranial in focus, RefleXion represents an emerging modality that could shift radiation oncology investment dollars toward next-generation platforms instead of dedicated cranial SRS like ZAP-X.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks7 records

Key highlights8 records

Customer concentration

• Xx.com/ZapSurgical
• YouTubeyoutube.com/channel/UCml4LQV5D2gRCk43XMO-0Cw/videos
• Facebookfacebook.com/zapsurgical
• LinkedInlinkedin.com/company/zapsurgical
• Instagraminstagram.com/zapsurgical

Compliance8 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles13 records

Subsidiaries3 records

Funding overview

Funding rounds3 records

Investors7 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Zap Surgical Systems